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Aliases for ERICH3 Gene

Aliases for ERICH3 Gene

  • Glutamate-Rich 3 2 3
  • C1orf173 3 4
  • Chromosome 1 Open Reading Frame 173 2
  • Glutamate-Rich Protein 3 3
  • RP11-653A5.1 3

External Ids for ERICH3 Gene

Previous HGNC Symbols for ERICH3 Gene

  • C1orf173

Previous GeneCards Identifiers for ERICH3 Gene

  • GC01M075034

Summaries for ERICH3 Gene

GeneCards Summary for ERICH3 Gene

ERICH3 (Glutamate-Rich 3) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ERICH3 Gene

Genomics for ERICH3 Gene

Genomic Location for ERICH3 Gene

74,568,111 bp from pter
74,674,329 bp from pter
106,219 bases
Minus strand

Genomic View for ERICH3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ERICH3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ERICH3 Gene

No data available for Regulatory Elements for ERICH3 Gene

Proteins for ERICH3 Gene

  • Protein details for ERICH3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Glutamate-rich protein 3
    Protein Accession:
    Secondary Accessions:
    • Q68DL8
    • Q6GMR8
    • Q6ZSF9
    • Q8ND41

    Protein attributes for ERICH3 Gene

    1530 amino acids
    Molecular mass:
    168466 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC86994.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};

    Alternative splice isoforms for ERICH3 Gene


neXtProt entry for ERICH3 Gene

Proteomics data for ERICH3 Gene at MOPED

Post-translational modifications for ERICH3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ERICH3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ERICH3 Gene

Domains for ERICH3 Gene

Protein Domains for ERICH3 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ERICH3: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ERICH3 Gene

Function for ERICH3 Gene

Phenotypes for ERICH3 Gene

GenomeRNAi human phenotypes for ERICH3:
genes like me logo Genes that share phenotypes with ERICH3: view

miRNA for ERICH3 Gene

miRTarBase miRNAs that target ERICH3

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ERICH3

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for ERICH3 Gene

Localization for ERICH3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ERICH3 Gene

Pathways for ERICH3 Gene

SuperPathways for ERICH3 Gene

No Data Available

Interacting Proteins for ERICH3 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000322609 Q5RHP9-ERIC3_HUMAN for ERICH3 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for ERICH3 Gene


No data available for Pathways by source for ERICH3 Gene

Transcripts for ERICH3 Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ERICH3

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ERICH3 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16
SP1: - - - -
SP2: -

Relevant External Links for ERICH3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ERICH3 Gene

mRNA expression in normal human tissues for ERICH3 Gene

mRNA differential expression in normal tissues according to GTEx for ERICH3 Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (5.7), Brain - Anterior cingulate cortex (BA24) (5.6), Brain - Nucleus accumbens (basal ganglia) (5.6), and Testis (4.9).

Protein differential expression in normal tissues for ERICH3 Gene

This gene is overexpressed in Neutrophil (33.4), Adrenal (17.8), and Testis (8.5).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for ERICH3 Gene

genes like me logo Genes that share expressions with ERICH3: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Expression partners for ERICH3 Gene

Orthologs for ERICH3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ERICH3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C3H1orf173 35
  • 77.71 (n)
  • 64.81 (a)
C1orf173 36
  • 73 (a)
(Canis familiaris)
Mammalia ERICH3 35
  • 85.45 (n)
  • 79.36 (a)
C1orf173 36
  • 60 (a)
(Mus musculus)
Mammalia 4922501L14Rik 35
  • 72.11 (n)
  • 62.2 (a)
4922501L14Rik 16
4922501L14Rik 36
  • 60 (a)
(Pan troglodytes)
Mammalia ERICH3 35
  • 98.91 (n)
  • 97.97 (a)
C1orf173 36
  • 98 (a)
(Rattus norvegicus)
Mammalia LOC295528 35
  • 69.45 (n)
  • 55.91 (a)
(Monodelphis domestica)
Mammalia C1orf173 36
  • 21 (a)
(Ornithorhynchus anatinus)
Mammalia C1orf173 36
  • 23 (a)
(Gallus gallus)
Aves C1orf173 36
  • 53 (a)
(Anolis carolinensis)
Reptilia C1orf173 36
  • 30 (a)
(Danio rerio)
Actinopterygii C8H1orf173 36
  • 35 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 53 (a)
Species with no ortholog for ERICH3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ERICH3 Gene

Gene Tree for ERICH3 (if available)
Gene Tree for ERICH3 (if available)

Paralogs for ERICH3 Gene

No data available for Paralogs for ERICH3 Gene

Variants for ERICH3 Gene

Sequence variations from dbSNP and Humsavar for ERICH3 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs471338 -- 74,661,788(-) TTCTT(A/G)TTTTC intron-variant
rs474954 -- 74,649,442(+) TATAT(C/G)TGTTT intron-variant
rs476332 -- 74,656,940(+) TCCTA(C/T)AAGGT intron-variant
rs483164 -- 74,637,165(+) GACTG(A/C)AGCTG intron-variant
rs484449 -- 74,656,290(+) aggtt(C/G)cctta intron-variant

Relevant External Links for ERICH3 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ERICH3 Gene

Disorders for ERICH3 Gene

No disorders were found for ERICH3 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ERICH3 Gene

Publications for ERICH3 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4

Products for ERICH3 Gene

Sources for ERICH3 Gene

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