ERI1 Gene
protein-coding GIFtS: 50
GCID: GC08P008900
|
|
exoribonuclease 1(Previous name: three prime histone mRNA exonuclease 1 )
(Previous symbol: THEX1)
| |
Aliases
for ERI1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Exoribonuclease 11 2 | | Eri-1 Homolog2 3 | | THEX11 2 3 | | 3' Exoribonuclease2 | | 3'HEXO1 2 | | 3'-5' Exoribonuclease 12 | | Three Prime Histone MRNA Exonuclease 11 2 | | Enhanced RNAi Three Prime MRNA Exonuclease Homolog 12 | | Histone MRNA 3'-End-Specific Exoribonuclease2 3 | | Histone MRNA 3' End-Specific Exonuclease2 | | Histone MRNA 3'-Exonuclease 12 3 | | Three Prime MRNA Exonuclease 12 | | Protein 3'HExo2 3 | | 3'EXO3 | | 3'-5' Exonuclease ERI12 3 | | EC 3.1.-.-3 | | HEXO2 3 | | |
Export aliases for ERI1 gene to outside databasesPrevious GC identifer: GC08P007785 |
Summaries
for ERI1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ERI1_HUMAN, Q8IV48Function: RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays anessential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of thehistone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of shortinterfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires forbinding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure ofreplication-dependent histone pre-mRNAs
|
Genomic Views
for ERI1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_077531.4
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ERI1 gene promoter:
ATF-2 Pax-2 POU6F1 (c2) Pax-2a HNF-3beta c-Ets-1 CRE-BP1 RORalpha1 Pax-2b Ik-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ERI1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ERI1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8p23.1 Ensembl cytogenetic band: 8p23.1 HGNC cytogenetic band: 8p23.1ERI1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08P008900: view genomic region
(about GC identifiers)
Start:
|
8,859,657 bp from pter |
End:
|
8,974,256 bp from pter |
Size:
|
114,600 bases |
Orientation:
|
plus strand |
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Proteins
for ERI1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ERI1_HUMAN, Q8IV48 (See
protein sequence)Recommended Name: 3'-5' exoribonuclease 1 Size: 349 amino acids; 40064 Da
Cofactor: Binds 2 magnesium ions per subunit
Subunit: Identified in a histone pre-mRNA complex, at least composed of ERI1, LSM11, SLBP, SNRPB, SYNCRIP and YBX1.Interacts in a cooperative manner with SLBP to the mature 3'-end of histone mRNAs (By similarity). Binds to 40S and60S ribosomal subunits and to 80S assembled ribosomes. Found in a ternary complex with SLBP and the stem-loopstructure of the 3'-end of histone mRNAs
Subcellular location: Cytoplasm. Nucleus. Nucleus, nucleolus
Sequence caution: Sequence=CAB70871.2; Type=Erroneous termination; Positions=159; Note=Translated as Leu;Sequence=CAB70871.2; Type=Frameshift; Positions=117;
4 PDB 3D structures from  and Proteopedia  for ERI1:1W0H (3D)
1ZBH (3D)
1ZBU (3D)
4HXH (3D)
Secondary accessions: A8K4U7 Q9NSX3Explore the universe of human proteins at neXtProt for ERI1: NX_Q8IV48
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IV48
ERI1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_699163.2
ENSEMBL proteins: ENSP00000429615 ENSP00000430190 ENSP00000429043 ENSP00000430651 ENSP00000250263
Human Recombinant Protein Products for ERI1:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
ERI1 for ontologies About GeneDecksing
ERI1 Antibody Products:
Assay Products for ERI1: |
Protein
Domains /
Families
for ERI1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ERI1 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8IV48ProtoNet protein and cluster: Q8IV48 2 Blocks protein families: IPB003034 DNA-binding SAP IPB006055 Exonuclease
UniProtKB/Swiss-Prot: ERI1_HUMAN, Q8IV48Domain: The SAP domain is necessary for binding to the stem-loop structure of histone mRNAs and to form the ternarycomplex with SLBP, but not for 3'-end histone mRNA exonuclease activitySimilarity: Contains 1 exonuclease domainSimilarity: Contains 1 SAP domain |
Function
for ERI1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ERI1_HUMAN, Q8IV48Function: RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays anessential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of thehistone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of shortinterfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires forbinding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure ofreplication-dependent histone pre-mRNAsEnzyme regulation: Although it can bind simultaneously with SLBP to the 3'-end of histone mRNA, the presence of SLBPprevents the exonuclease activity Enzyme Number (IUBMB): EC 3.1.-.-1
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
ERI1 for ontologies About GeneDecksing
Phenotypes:
4 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Eri1):
ERI1 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Eri1tm1.2Anse for ERI1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ERI1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ERI1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ERI1 (NM_153332) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ERI1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ERI1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ERI1 |
|
Pathways & Interactions
for ERI1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Chromatin Regulation / Acetylation | | | 2 | Translational Control | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Cell Signaling Technology (CST) Pathways for ERI1
ERI1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ERI1
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for ERI1 (Q8IV483 ENSP000002502634) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
ERI1 for ontologies About GeneDecksing
|
Drugs & Compounds
for ERI1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ERI1
1 HMDB Compound for ERI1 About this table
Search CenterWatch for drugs/clinical trials and news about ERI1
|
Transcripts
for ERI1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ERI1 gene: NM_153332.3 Unigene Cluster for ERI1: Exoribonuclease 1 Hs.20000 [show with all ESTs]Unigene Representative Sequence: NM_1533329 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000523898 ENST00000519292 ENST00000521844 ENST00000520684 ENST00000520332
ENST00000518663 ENST00000522612 ENST00000522258 ENST00000250263(uc003wsk.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ERI1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ERI1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ERI1 (NM_153332) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ERI1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ERI1 |
Additional cDNA sequence: AK024646.1 AK226180.1 AK291062.1 AK301506.1 AL137679.1 AY310909.1 BC035279.1 11 DOTS entries: DT.214460 DT.101957634 DT.100788000 DT.100034162 DT.121471129 DT.86835774 DT.86839753 DT.95369395 DT.102826518 DT.425684 DT.70101834 24/154 AceView cDNA sequences (see all 154): AY310909 CB106489 CA425553 AL603275 BC035279 BM148154 BG198861 AI290582 CR593780 NM_153332 AI733576 AW193640 BX475163 BG209306 BX955782 BI764357 CD107156 BU620343 CF994236 AA535614 AI784638 AA588412 BX955796 BG283229
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for ERI1 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 |
|---|
|
| SP1: | | | | | - | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ERI1
|
Expression
for ERI1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ERI1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTTTGAAATA
About this image
See ERI1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ERI1
SOURCE GeneReport for Unigene cluster: Hs.20000
SABiosciences Custom PCR Arrays for ERI1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ERI1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ERI1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ERI1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ERI1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ERI1 |
Orthologs
for ERI1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ERI1 gene from 7/23 species (see all 23) About this table
ENSEMBL Gene Tree for ERI1 (if available)
TreeFam Gene Tree for ERI1 (if available) |
Paralogs
for ERI1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ERI1 gene
- ERI22 ERI32
ERI1 for paralogs About GeneDecksing
|
Genomic Variants
for ERI1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ERI1 (8859657 - 8974256 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 16 variations for ERI1
15/16 Inversions (see all 16): 37318 37316 37307 37317 37311 37319 37320 37315 37312 37321 37304 37313 37314 37305 37306 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ERI1 |
|
Disorders
/ Diseases
for ERI1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ERI1 for disorders About GeneDecksing
OMIM gene information: 608739
OMIM disorders: --
1  disease for ERI1: About MalaCardsneuronitis
Human Genome Epidemiology (HuGE) Navigator: ERI1 (1 document)
Export disorders for ERI1 gene to outside databases
|
Publications
for ERI1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ERI1 gene, integrated from 9 sources (see all 21):
(articles sorted by number of sources associating them with ERI1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A 3' exonuclease that specifically interacts with the 3' end of histone mRNA. (PubMed id 14536070)1, 2, 3 Dominski Z.... Marzluff W.F. (2003)
- Characterization of 3'hExo, a 3' exonuclease specifically interacting with the 3' end of histone mRNA. (PubMed id 16912046)1, 2, 9 Yang X.-C.... Dominski Z. (2006)
- Crystallographic structure of the nuclease domain of 3'hExo, a DEDDh family member, bound to rAMP. (PubMed id 15451662)1, 2, 9 Cheng Y. and Patel D.J. (2004)
- A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans. (PubMed id 14961122)1, 2 Kennedy S.... Ruvkun G. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Structure of histone mRNA stem-loop, human stem-loop b inding protein, and 3'hExo ternary complex. (PubMed id 23329046)1 Tan D....Tong L. (2013)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- A protein array screen for Kaposi's sarcoma-associated herpesvirus LANA interactors links LANA to TIP60, PP2A activity, and telomere s hortening. (PubMed id 22379092)1 Shamay M....Hayward S.D. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
|
External Searches for ERI1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ERI1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ERI1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ERI1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ERI1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ERI1 gene:
Search GeneIP for patents involving ERI1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ERI1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for ERI1 | | OriGene shRNA RFP for ERI1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ERI1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ERI1 | | | OriGene Protein Over-expression Lysate for ERI1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for ERI1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ERI1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ERI1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ERI1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ERI1 | | OriGene Custom Protein Services for ERI1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ERI1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ERI1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ERI1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ERI1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ERI1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ERI1 |
| |
 |  |  |  | |
| | Antibodies & Assays for ERI1 (THEX1) |
| | | | Search Tocris compounds for ERI1 |
| |  |  |  |  | | | | |
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 |
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 | | | ERI1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ERI1 |
|  |  |  |  | | | | ThermoFisher Antibodies for ERI1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ERI1 |
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