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ERH Gene

protein-coding   GIFtS: 55
GCID: GC14M069846

Enhancer Of Rudimentary Homolog (Drosophila)

(Previous name: enhancer of rudimentary (Drosophila) homolog)
  Search for ERH
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Enhancer Of Rudimentary Homolog (Drosophila)1 2
Enhancer Of Rudimentary (Drosophila) Homolog1
DROER2
Enhancer Of Rudimentary Homolog2

External Ids:    HGNC: 34471   Entrez Gene: 20792   Ensembl: ENSG000001006327   OMIM: 6011915   UniProtKB: P840903   

Export aliases for ERH gene to outside databases

Previous GC identifers: GC14M067352 GC14M063643 GC14M067836 GC14M068916 GC14M050015


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ERH Gene:
ERH (enhancer of rudimentary homolog (Drosophila)) is a protein-coding gene.

UniProtKB/Swiss-Prot: ERH_HUMAN, P84090
Function: May have a role in the cell cycle

Gene Wiki entry for ERH Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000014.9  NC_018925.2  NT_026437.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the ERH gene promoter:
         GR   LHX3b/Lhx3b   p300   HNF-1A   E2F-1   E2F   deltaCREB   HNF-1   LHX3a/Lhx3a   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ERH promoter sequence
   Search Chromatin IP Primers for ERH

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ERH


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q24.1|7q34   Ensembl cytogenetic band:  14q24.1   HGNC cytogenetic band: 14q24.1

ERH Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ERH gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M069846:  view genomic region     (about GC identifiers)

Start:
69,846,840 bp from pter      End:
69,865,344 bp from pter
Size:
18,505 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ERH_HUMAN, P84090 (See protein sequence)
Recommended Name: Enhancer of rudimentary homolog  
Size: 104 amino acids; 12259 Da
Subunit: Homodimer (By similarity). Interacts with POLDIP3
2 PDB 3D structures from and Proteopedia for ERH:
1W9G (3D)        2NML (3D)    
Secondary accessions: B2R5H2 P70659 Q14259

Explore the universe of human proteins at neXtProt for ERH: NX_P84090

Explore proteomics data for ERH at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys12, Lys41, Lys84, Lys90
  • Modification sites at PhosphoSitePlus

  • See ERH Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_004441.1  
    ENSEMBL proteins: 
     ENSP00000451080   ENSP00000450503  

    ERH Human Recombinant Protein Products:

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    Novus Biologicals ERH Lysate
    Sino Biological Recombinant Protein for ERH
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for ERH
    Cloud-Clone Corp. Proteins for ERH

     
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    LSBio Antibodies in human, mouse, rat for ERH

    ERH Assay Products:

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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ERH
    Cloud-Clone Corp. CLIAs for ERH
    Search eBioscience for ELISAs for ERH 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR000781 Enh_rudimentary

    Graphical View of Domain Structure for InterPro Entry P84090

    ProtoNet protein and cluster: P84090

    UniProtKB/Swiss-Prot: ERH_HUMAN, P84090
    Similarity: Belongs to the E(R) family


    Find genes that share domains with ERH           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ERH_HUMAN, P84090
    Function: May have a role in the cell cycle

         Genatlas biochemistry entry for ERH:
    Drosophila enhancer of the rudimentary gene DROER,homolog,ubiquitously expressed

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with ERH           About GenesLikeMe


    Phenotypes:
         6 GenomeRNAi human phenotypes for ERH:
     Cell cycle / mitosis defect  Cell division defect  Increased G2M DNA content  Increased gamma-H2AX phosphory 
     Increased number of mitotic ce  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ERH
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ERH

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ERH
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ERH

    miRNA
    Products:
        
    miRTarBase miRNAs that target ERH:
    hsa-mir-92a-3p (MIRT049758)

    Block miRNA regulation of human, mouse, rat ERH using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate ERH:
    hsa-miR-4261 hsa-miR-362-3p hsa-miR-1323 hsa-miR-548o hsa-miR-329
    SwitchGear 3'UTR luciferase reporter plasmidERH 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ERH
    Predesigned siRNA for gene silencing in human, mouse, rat ERH

    Gene Editing
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    OriGene ORF clones in mouse, rat for ERH
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ERH (NM_004450)
    Sino Biological Human cDNA Clone for ERH
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ERH
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ERH

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for ERH 
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ERH


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    plasma membrane2
    extracellular1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030496midbody IDA15166316

    Find genes that share ontologies with ERH           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ERH
    Interactions:

        GeneGlobe Interaction Network for ERH

    Selected Interacting proteins for ERH (P840902, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 64)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CTDP1Q9Y5B02, 3MINT-51652 MINT-51649 I2D: score=4 
    COPS6Q7L5N12, 3MINT-64024 I2D: score=5 
    HSPA8P111422, 3MINT-63448 I2D: score=5 
    MED31Q9Y3C72, 3MINT-64028 I2D: score=5 
    SETDB1Q150472, 3MINT-64023 I2D: score=5 
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006139nucleobase-containing compound metabolic process TAS9074495
    GO:0006213pyrimidine nucleoside metabolic process TAS8786099
    GO:0007049cell cycle IEA--

    Find genes that share ontologies with ERH           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ERH



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ERH gene: 
    NM_004450.2  

    Unigene Cluster for ERH:

    Enhancer of rudimentary homolog (Drosophila)
    Hs.509791  [show with all ESTs]
    Unigene Representative Sequence: BQ956733
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000557016(uc001xlc.2) ENST00000216520 ENST00000557697 ENST00000555373

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ERH using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate ERH:
    hsa-miR-4261 hsa-miR-362-3p hsa-miR-1323 hsa-miR-548o hsa-miR-329
    SwitchGear 3'UTR luciferase reporter plasmidERH 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ERH
    Predesigned siRNA for gene silencing in human, mouse, rat ERH
    Clone
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    OriGene clones in human, mouse for ERH (see all 6)
    OriGene ORF clones in mouse, rat for ERH
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ERH (NM_004450)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ERH
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ERH
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ERH
    OriGene qSTAR qPCR primer pairs in human, mouse for ERH
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ERH
      QuantiTect SYBR Green Assays in human, mouse, rat ERH
      QuantiFast Probe-based Assays in human, mouse, rat ERH

    Additional mRNA sequence: 

    AK130850.1 AK312186.1 BC014301.2 BC071709.1 BT006877.1 CR450298.1 CR542178.1 D85758.1 
    U66871.1 

    19 DOTS entries:

    DT.100033245  DT.100033139  DT.418339  DT.95319046  DT.100815696  DT.120778709  DT.95247009  DT.120778739 
    DT.120778758  DT.100045840  DT.92441639  DT.95246991  DT.100815690  DT.92441638  DT.95247003  DT.100704839 
    DT.100815689  DT.101985095  DT.121128839 

    Selected AceView cDNA sequences (see all 471):

    AA304707 AI357037 AI468145 CA848811 BM723352 CA421504 N90271 BU726586 
    AA251041 BU622711 CA430757 CB126653 AA991960 BU682272 AK130850 BQ773898 
    BM791946 BM509606 BU152992 BU951006 CA773307 BC014301 CR542178 CA308241 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for ERH    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b
    SP1:                                -               
    SP2:                                                
    SP3:                    -           -               


    ECgene alternative splicing isoforms for ERH

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ERH expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCCTCAAGAT
    ERH Expression
    About this image


    ERH expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 13) fully expand
     
     Brain (Nervous System)    fully expand to see all 6 entries
             Cerebral Cortex
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Metencephalon
     
     Lung (Respiratory System)    fully expand to see all 2 entries
             Stem Bronchi
     
     Kidney (Urinary System)
             Metanephros
     
     Thymus (Hematopoietic System)
             Thymus
    ERH Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ERH Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.509791

    UniProtKB/Swiss-Prot: ERH_HUMAN, P84090
    Tissue specificity: Expressed in all tissues examined

        Custom PCR Arrays for ERH
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    QuantiFast Probe-based Assays in human, mouse, rat ERH
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ERH

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ERH gene from Selected species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Erh1 , 5 enhancer of rudimentary homolog (Drosophila)1, 5 92.95(n)1
    100(a)1
      12 (36.90 cM)5
    138771  NM_007951.31  NP_031977.11 
     806340225 
    chicken
    (Gallus gallus)
    Aves ERH1 enhancer of rudimentary homolog (Drosophila) 84.62(n)
    98.08(a)
      423262  NM_001006475.1  NP_001006475.1 
    lizard
    (Anolis carolinensis)
    Reptilia ERH6
    enhancer of rudimentary homolog (Drosophila)
    99(a)
    1 ↔ 1
    GL343318.1(430949-440717)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.44232 Xenopus laevis enhancer of rudimentary homologue ERH more 83.28(n)    AF124330.1 
    zebrafish
    (Danio rerio)
    Actinopterygii e(r)2 enhancer of rudimentary 84.23(n)   30475  BC059528.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta e(r)1 , 3 regulation of transcription from Pol II
    promoter more3
    enhancer of rudimentary1
    79(a)3
    67.68(n)1
    79.8(a)1
      1 8B73
    439511  NM_001272434.11  NP_001259363.11 
    worm
    (Caenorhabditis elegans)
    Secernentea T21C9.41 T21C9.4 53.06(n)
    56.12(a)
      179476  NM_073312.5  NP_505713.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons ER1 ER 51.33(n)
    45(a)
      830948  NM_121119.2  NP_568240.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g06114501 Os02g0611450 53.54(n)
    45.45(a)
      9270484  NM_001186141.1  NP_001173070.1 


    ENSEMBL Gene Tree for ERH (if available)
    TreeFam Gene Tree for ERH (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ERH gene

    Find genes that share paralogs with ERH           About GenesLikeMe


    3 Pseudogenes.org Pseudogenes for ERH
    PGOHUM00000261957 PGOHUM00000243206 PGOHUM00000233594


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ERH (see all 414)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1906166501,2
    --69846424(+) ACTTTC/TTTGTG 1 -- ds50010--------
    rs784748201,2
    F--69846460(+) CCTACA/GGTAGT 1 -- ds50011Minor allele frequency- G:0.02WA 118
    rs788233811,2
    C,F--69846473(+) GTAACT/CAGTAT 1 -- ds50013Minor allele frequency- C:0.18NA CSA 124
    rs770250341,2
    F--69846532(+) TTCATC/TTGATC 1 -- ds50011Minor allele frequency- T:0.02WA 118
    rs1835887031,2
    --69846581(+) GACAAA/GCTTTA 1 -- ds50010--------
    rs1402470621,2
    --69846604(+) CATTTA/GTAACG 1 -- ds50010--------
    rs1889819231,2
    --69846614(+) GTTTGC/TGTCAA 1 -- ds50010--------
    rs2000790701,2
    --69846696(+) TTAGC-/TTCACA
            
    TTCAC
    1 -- cds10--------
    rs1118406781,2
    C--69846697(+) TAGCTTCACA   
      TAAA
    /-
    TCACA
    1 -- cds11Minor allele frequency- -:0.50CSA 2
    rs1995862741,2
    C--69846704(-) ATTTTG/TCTGTG 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for ERH (69846840 - 69865344 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for ERH: --
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing ERH
    DNA2.0 Custom Variant and Variant Library Synthesis for ERH

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 601191    OMIM disorders: --


    Find genes that share disorders with ERH           About GenesLikeMe


    Export disorders for ERH gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ERH gene, integrated from 10 sources (see all 44):
    (articles sorted by number of sources associating them with ERH)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and mapping of a novel human cDNA homologous to DROER, the enhancer of the Drosophila melanogaster rudimentary gene. (PubMed id 8786099)1, 2, 3, 9 Isomura M.... Nakamura Y. (Genomics 1996)
    2. The putative cell cycle gene, enhancer of rudimentary, encodes a highly conserved protein found in plants and animals. (PubMed id 9074495)1, 2, 3 Gelsthorpe M.... Tsubota S.I. (Gene 1997)
    3. Structure of the conserved transcriptional repressor enhancer of rudimentary homolog. (PubMed id 15794639)1, 2 Wan C.... Rose R.B. (Biochemistry 2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    6. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    7. Identification and functional analysis of the erh1(+) gene encoding enhancer of rudimentary homolog from the fission yeast Schizosaccharomyces pombe. (PubMed id 23145069)1 Krzyzanowski M.K....Kozlowski P. (PLoS ONE 2012)
    8. The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus. (PubMed id 23084401)1 Singh G....Moore M.J. (Cell 2012)
    9. Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production. (PubMed id 22174317)1 Naji S....Gerace L. (amp 2012)
    10. Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells. (PubMed id 23236152)1 Weng M.T....Luo J. (Proc. Natl. Acad. Sci. U.S.A. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 2079 HGNC: 3447 AceView: ERH Ensembl:ENSG00000100632 euGenes: HUgn2079
    ECgene: ERH H-InvDB: ERH

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ERH Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ERH Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ERH gene:
    Search GeneIP for patents involving ERH

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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