Aliases for ERCC5 Gene
Aliases for ERCC5 Gene
- ERCC Excision Repair 5, Endonuclease 2 3 5
- Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 5 2 3
- Xeroderma Pigmentosum, Complementation Group G 2 3
- Excision Repair Cross-Complementation Group 5 2 3
- DNA Excision Repair Protein ERCC-5 3 4
- ERCM2 3 4
- XPGC 3 4
- XPG 3 4
- Xeroderma Pigmentosum Group G-Complementing Protein 4
External Ids for ERCC5 Gene
- HGNC: 3437
- Entrez Gene: 2073
- Ensembl: ENSG00000134899
- OMIM: 133530
- UniProtKB: P28715
Previous HGNC Symbols for ERCC5 Gene
- ERCM2
- XPGC
Previous GeneCards Identifiers for ERCC5 Gene
- GC13P101858
- GC13P097885
- GC13P102334
- GC13P101196
- GC13P102296
- GC13P103497
- GC13P084090
- GC13P103459
Summaries for ERCC5 Gene
-
This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, cognitive disability, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene. [provided by RefSeq, Feb 2011]
GeneCards Summary for ERCC5 Gene
ERCC5 (ERCC Excision Repair 5, Endonuclease) is a Protein Coding gene. Diseases associated with ERCC5 include Xeroderma Pigmentosum, Complementation Group G and Cerebrooculofacioskeletal Syndrome 3. Among its related pathways are Nucleotide excision repair and Transcription-Coupled Nucleotide Excision Repair (TC-NER). Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein N-terminus binding. An important paralog of this gene is BIVM-ERCC5.
UniProtKB/Swiss-Prot for ERCC5 Gene
-
Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too.
Additional gene information for ERCC5 Gene
- Monarch Initiative
- Search for ERCC5 at DataMed
- Search for ERCC5 at HumanCyc
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ERCC5 Gene
Genomics for ERCC5 Gene
GeneHancer (GH) Regulatory Elements for ERCC5 Gene
Regulatory Element Products
Genomic Locations for ERCC5 Gene
- chr13:102,844,844-102,876,001
- (GRCh38/hg38)
- Size:
- 31,158 bases
- Orientation:
- Plus strand
- chr13:103,497,194-103,528,351
- (GRCh37/hg19)
Genomic View for ERCC5 Gene
- Cytogenetic band:
-
- 13q33.1 by Ensembl
- 13q33.1 by Entrez Gene
- 13q33.1 by HGNC


RefSeq DNA sequence for ERCC5 Gene
Proteins for ERCC5 Gene
-
Protein details for ERCC5 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P28715-ERCC5_HUMAN
- Recommended name:
- DNA repair protein complementing XP-G cells
- Protein Accession:
- P28715
- A6NGT4
- Q5JUS4
- Q5JUS5
- Q7Z2V3
- Q8IZL6
- Q8N1B7
- Q9HD59
- Q9HD60
Protein attributes for ERCC5 Gene
- Size:
- 1186 amino acids
- Molecular mass:
- 133108 Da
- Cofactor:
- Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
- Quaternary structure:
-
- Interacts with PCNA.
Protein Expression for ERCC5 Gene
Post-translational modifications for ERCC5 Gene
- Ubiquitination at posLast=172172, posLast=293293, posLast=298298, and posLast=313313
Other Protein References for ERCC5 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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Assay Products
No data available for DME Specific Peptides for ERCC5 Gene
Domains & Families for ERCC5 Gene
Gene Families for ERCC5 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Disease related genes
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for ERCC5 Gene
Suggested Antigen Peptide Sequences for ERCC5 Gene
- GenScript: Design optimal peptide antigens:
-
- Xeroderma pigmentosum group G-complementing protein (ERCC5_HUMAN)
- Excision repair cross-complementing rodent repair deficiency, complementation group 5 (Xeroderma pigmentosum, complementation group G (Cockayne syndrome)) (Q5JUS1_HUMAN)
- Xeroderma pigmentosum complementation group G protein splice variant (Q9HD60_HUMAN)
- Xeroderma pigmentosum complementation group G protein splice variant (Q9NR54_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P28715- Family:
-
- Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
Function for ERCC5 Gene
Molecular function for ERCC5 Gene
- GENATLAS Biochemistry:
- excision repair cross-complementing rodent repair defect in CHO cells,complementation group 5,yeast RAD2 homolog (see XPG),deleted in metastatic prostate carcinomas
- UniProtKB/Swiss-Prot Function:
- Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too.
Enzyme Numbers (IUBMB) for ERCC5 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000405 | bubble DNA binding | IDA | 16246722 |
GO:0003677 | DNA binding | IEA | -- |
GO:0003690 | double-stranded DNA binding | IDA | 8090225 |
GO:0003697 | single-stranded DNA binding | IDA | 12644470 |
GO:0003824 | catalytic activity | IEA | -- |
Phenotypes for ERCC5 Gene
- MGI mutant phenotypes for ERCC5:
- inferred from 4 alleles
- GenomeRNAi human phenotypes for ERCC5:
Animal Model Products
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miRNA for ERCC5 Gene
- miRTarBase miRNAs that target ERCC5
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-
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No data available for Phenotypes From GWAS Catalog , Transcription Factor Targets and HOMER Transcription for ERCC5 Gene
Localization for ERCC5 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ERCC5 Gene
- Nucleus.
- Nucleoplasm (3)
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IDA | 8710877 |
GO:0005654 | nucleoplasm | TAS | -- |
GO:0005662 | colocalizes_with DNA replication factor A complex | IDA | 7700386 |
GO:0005675 | colocalizes_with holo TFIIH complex | IDA | 11259578 |
GO:0016591 | colocalizes_with DNA-directed RNA polymerase II, holoenzyme | IDA | 16246722 |
Pathways & Interactions for ERCC5 Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Transcription-Coupled Nucleotide Excision Repair (TC-NER) | ||
2 | Nucleotide excision repair | ||
3 | Chks in Checkpoint Regulation | ||
4 | DNA Double-Strand Break Repair |
.53
|
Pathways by source for ERCC5 Gene
7 Reactome pathways for ERCC5 Gene
1 KEGG pathway for ERCC5 Gene
2 Qiagen pathways for ERCC5 Gene
Interacting Proteins for ERCC5 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006281 | DNA repair | IEA | -- |
GO:0006283 | transcription-coupled nucleotide-excision repair | TAS,IMP | -- |
GO:0006289 | nucleotide-excision repair | IEA | -- |
GO:0006293 | nucleotide-excision repair, preincision complex stabilization | TAS | -- |
GO:0006294 | nucleotide-excision repair, preincision complex assembly | TAS | -- |
No data available for SIGNOR curated interactions for ERCC5 Gene
Drugs & Compounds for ERCC5 Gene
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
platinum | Investigational | Pharma | 0 |
Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
---|
Transcripts for ERCC5 Gene
mRNA/cDNA for ERCC5 Gene
- (1) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (9) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ERCC5 Gene
- Excision repair cross-complementing rodent repair deficiency, complementation group 5:
- Representative Sequences:
CRISPR Products
-
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Clone Products
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- Applied Biological Materials Clones for ERCC5
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
SP2: | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
SP3: | - | ||||||||||||||||||||||||||||||||||||||||||||||||
SP4: | |||||||||||||||||||||||||||||||||||||||||||||||||
SP5: | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
SP6: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
SP7: |
Expression for ERCC5 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Heart (Cardiovascular System)
- Atrioventricular Node Cells Atrioventricular Node
-
Testis (Reproductive System)
- Leydig Cells Testis Interstitium
- Brain (Nervous System)
- Thyroid (Endocrine System)
- Intestine (Gastrointestinal Tract)
- Ovary (Reproductive System)
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ERCC5 Gene
NURSA nuclear receptor signaling pathways regulating expression of ERCC5 Gene:
ERCC5SOURCE GeneReport for Unigene cluster for ERCC5 Gene:
Hs.258429Evidence on tissue expression from TISSUES for ERCC5 Gene
- Bone marrow(4.3)
- Eye(4.1)
- Nervous system(4)
- Lung(2.2)
Phenotype-based relationships between genes and organs from Gene ORGANizer for ERCC5 Gene
- ectoderm
- endoderm
- mesoderm
- cardiovascular
- endocrine
- immune
- integumentary
- lymphatic
- nervous
- reproductive
- respiratory
- skeletal muscle
- skeleton
- brain
- cerebellum
- chin
- cranial nerve
- ear
- eye
- eyelid
- face
- forehead
- head
- jaw
- lip
- mandible
- maxilla
- mouth
- neck
- nose
- outer ear
- skull
- breast
- chest wall
- clavicle
- lung
- rib
- rib cage
- scapula
- sternum
- pelvis
- penis
- testicle
- ankle
- arm
- digit
- elbow
- femur
- fibula
- finger
- foot
- forearm
- hand
- hip
- humerus
- knee
- lower limb
- radius
- shin
- shoulder
- thigh
- tibia
- toe
- ulna
- upper limb
- wrist
- blood vessel
- hair
- peripheral nerve
- peripheral nervous system
- skin
- spinal column
- spinal cord
- vertebrae
Primer Products
-
OriGene qPCR primer pairs for ERCC5
-
OriGene qPCR primer pairs and template standards for ERCC5
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No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ERCC5 Gene
Orthologs for ERCC5 Gene
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | ERCC5 33 |
|
||
dog (Canis familiaris) |
Mammalia | ERCC5 33 |
|
||
BIVM 34 |
|
OneToMany | |||
cow (Bos Taurus) |
Mammalia | ERCC5 33 34 |
|
||
mouse (Mus musculus) |
Mammalia | Ercc5 33 16 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | Ercc5 33 |
|
||
platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
chicken (Gallus gallus) |
Aves | ERCC5 34 33 |
|
OneToMany | |
lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToMany | |
African clawed frog (Xenopus laevis) |
Amphibia | XPGC 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | ercc5 34 |
|
OneToMany | |
fruit fly (Drosophila melanogaster) |
Insecta | mus201 35 34 |
|
||
worm (Caenorhabditis elegans) |
Secernentea | gen-1 34 |
|
ManyToMany | |
xpg-1 34 |
|
ManyToMany | |||
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | RAD2 34 |
|
OneToMany | |
sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for ERCC5 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Paralogs for ERCC5 Gene
Paralogs for ERCC5 Gene
(1) SIMAP similar genes for ERCC5 Gene using alignment to 3 proteins:
Variants for ERCC5 Gene
SNP ID | Clin | Chr 13 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1047768 | conflicting-interpretations-of-pathogenicity, benign, not specified, Xeroderma pigmentosum | 102,852,167(+) | T/C | coding_sequence_variant, synonymous_variant | |
rs1047769 | not-provided, conflicting-interpretations-of-pathogenicity, likely-benign, not specified, Xeroderma pigmentosum | 102,861,594(+) | A/G | coding_sequence_variant, missense_variant | |
rs1057518813 | likely-pathogenic, Abnormality of the corpus callosum, Cerebellar atrophy, Cognitive impairment, Dysarthria, Pectus excavatum, Pes cavus, Polyneuropathy, Spastic paraplegia | 102,873,305(+) | TCTCT/TCT | coding_sequence_variant, frameshift | |
rs121434570 | pathogenic, Xeroderma pigmentosum, group G | 102,872,397(+) | G/A/T | coding_sequence_variant, missense_variant, stop_gained | |
rs121434571 | pathogenic, Xeroderma pigmentosum, group G, Xeroderma pigmentosum complementation group G (XP-G) [MIM:278780] | 102,866,687(+) | C/A/T | coding_sequence_variant, missense_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2661939 | CNV | deletion | 23128226 |
esv3633382 | CNV | loss | 21293372 |
nsv562981 | CNV | gain | 21841781 |
Additional Variant Information for ERCC5 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ERCC5 Gene
Disorders for ERCC5 Gene

(15) MalaCards diseases for ERCC5 Gene - From: HGMD, OMIM, ClinVar, GTR, Swiss-Prot, DISEASES, Novoseek, and GeneCards
Disorder | Aliases | PubMed IDs |
---|---|---|
xeroderma pigmentosum, complementation group g |
|
|
cerebrooculofacioskeletal syndrome 3 |
|
|
cockayne syndrome |
|
|
xeroderma pigmentosum, variant type |
|
|
cerebro-oculo-facio-skeletal syndrome |
|
|
UniProtKB/Swiss-Prot
ERCC5_HUMAN- Cerebro-oculo-facio-skeletal syndrome 3 (COFS3) [MIM:616570]: A disorder of prenatal onset characterized by microcephaly, congenital cataracts, facial dysmorphism, neurogenic arthrogryposis, growth failure and severe psychomotor retardation. COFS is considered to be part of the nucleotide-excision repair disorders spectrum that include also xeroderma pigmentosum, trichothiodystrophy and Cockayne syndrome. {ECO:0000269 PubMed:24700531}. Note=The disease is caused by mutations affecting the gene represented in this entry.
- Xeroderma pigmentosum complementation group G (XP-G) [MIM:278780]: An autosomal recessive pigmentary skin disorder characterized by solar hypersensitivity of the skin, high predisposition for developing cancers on areas exposed to sunlight and, in some cases, neurological abnormalities. The skin develops marked freckling and other pigmentation abnormalities. Some XP-G patients present features of Cockayne syndrome, cachectic dwarfism, pigmentary retinopathy, ataxia, decreased nerve conduction velocities. The phenotype combining xeroderma pigmentosum and Cockayne syndrome traits is referred to as XP-CS complex. {ECO:0000269 PubMed:10447254, ECO:0000269 PubMed:11228268, ECO:0000269 PubMed:11841555, ECO:0000269 PubMed:12060391, ECO:0000269 PubMed:23255472, ECO:0000269 PubMed:7951246, ECO:0000269 PubMed:9096355}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for ERCC5
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for ERCC5 Gene
Publications for ERCC5 Gene
- Association and impact of XPG Asp 1104 His gene polymorphism in HIV 1 disease progression to AIDS among north Indian HIV seropositive individuals. (PMID: 19693700) Sobti RC … Wanchu A (Molecular biology reports 2010) 3 22 44 58
- Polymorphisms in XRCC1 and XPG and response to platinum-based chemotherapy in advanced non-small cell lung cancer patients. (PMID: 19157633) Sun X … Yingfeng Z (Lung cancer (Amsterdam, Netherlands) 2009) 3 22 44 58
- Polymorphisms in nucleotide excision repair genes, polycyclic aromatic hydrocarbon-DNA adducts, and breast cancer risk. (PMID: 17932351) Crew KD … Santella RM (Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007) 3 22 44 58
- Single nucleotide polymorphism analysis of the nucleotide excision repair genes XPC, XPA, and XPG in the Indian population. (PMID: 18478970) Gowda S … Rao MR (Human biology 2007) 3 22 44 58
- Influence of polymorphisms in xenobiotic-metabolizing genes and DNA-repair genes on diepoxybutane-induced SCE frequency. (PMID: 17078101) Laczmanska I … Sasiadek MM (Environmental and molecular mutagenesis 2006) 3 22 44 58
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- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for ERCC5
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for ERCC5
- antibodies-online: Search results for 92 available ERCC5 Antibodies ranked by validation data
- Compare Top ERCC5 Antibodies
- antibodies-online: Search results for 9 available ERCC5 Elisa Kits ranked by validation data
- Compare Top ERCC5 Elisa Kits
- Recommended
- antibodies-online: Search results for 5 available ERCC5 Proteins ranked by validation data
- Compare Top ERCC5 Proteins
- GeneTex ERCC5 antibody for ERCC5
- Search GeneTex for Proteins for ERCC5
- ViGene Biosciences adenoviral particle packaged cDNA for ERCC5 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ERCC5 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ERCC5 gene
- Search ViGene Biosciences for ERCC5
- Santa Cruz Biotechnology (SCBT) Antibodies for ERCC5
- Search Santa Cruz Biotechnology (SCBT) for ERCC5 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ERCC5
- Horizon Cell Lines for ERCC5
- genomics-online: cdna clones - Search results for available ERCC5 gene related products
- orf clones - Search results for available ERCC5 gene related products
- genomics-online: gRNA clones - Search results for available ERCC5 gene related products
- genomics-online: primer clones - Search results for available ERCC5 gene related products
- genomics-online: shRNA clones - Search results for available ERCC5 gene related products
Sources for ERCC5 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew