Aliases for ERCC5 Gene
Aliases for ERCC5 Gene
- Excision Repair Cross-Complementation Group 5 2 3 5
- Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 5 2 3
- Xeroderma Pigmentosum, Complementation Group G 2 3
- DNA Excision Repair Protein ERCC-5 3 4
- ERCM2 3 4
- XPGC 3 4
- XPG 3 4
- Xeroderma Pigmentosum Group G-Complementing Protein 4
External Ids for ERCC5 Gene
- HGNC: 3437
- Entrez Gene: 2073
- Ensembl: ENSG00000134899
- OMIM: 133530
- UniProtKB: P28715
Previous HGNC Symbols for ERCC5 Gene
- ERCM2
- XPGC
Previous GeneCards Identifiers for ERCC5 Gene
- GC13P101858
- GC13P097885
- GC13P102334
- GC13P101196
- GC13P102296
- GC13P103497
- GC13P084090
- GC13P103459
Summaries for ERCC5 Gene
-
This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene. [provided by RefSeq, Feb 2011]
GeneCards Summary for ERCC5 Gene
ERCC5 (Excision Repair Cross-Complementation Group 5) is a Protein Coding gene. Diseases associated with ERCC5 include Xeroderma Pigmentosum, Group G and Cerebrooculofacioskeletal Syndrome 3. Among its related pathways are p53 Pathway (RnD) and Transcription-Coupled Nucleotide Excision Repair (TC-NER). GO annotations related to this gene include protein homodimerization activity and protein N-terminus binding. An important paralog of this gene is BIVM-ERCC5.
UniProtKB/Swiss-Prot for ERCC5 Gene
-
Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ERCC5 Gene
Genomics for ERCC5 Gene
Regulatory Elements for ERCC5 Gene
Enhancers for ERCC5 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around ERCC5 on UCSC Golden Path with GeneCards custom track
Promoters for ERCC5 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around ERCC5 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for ERCC5 Gene
- Chromosome:
- 13
- Start:
- 102,844,844 bp from pter
- End:
- 102,876,001 bp from pter
- Size:
- 31,158 bases
- Orientation:
- Plus strand
Genomic View for ERCC5 Gene
Genes around ERCC5 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 13q33.1 by Ensembl
- 13q33 by Entrez Gene
- 13q22-q34 by HGNC
ERCC5 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ERCC5 Gene
Proteins for ERCC5 Gene
-
Protein details for ERCC5 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P28715-ERCC5_HUMAN
- Recommended name:
- DNA repair protein complementing XP-G cells
- Protein Accession:
- P28715
- A6NGT4
- Q5JUS4
- Q5JUS5
- Q7Z2V3
- Q8IZL6
- Q8N1B7
- Q9HD59
- Q9HD60
Protein attributes for ERCC5 Gene
- Size:
- 1186 amino acids
- Molecular mass:
- 133108 Da
- Cofactor:
- Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
- Quaternary structure:
-
- Interacts with PCNA.
Protein Expression for ERCC5 Gene
Post-translational modifications for ERCC5 Gene
Other Protein References for ERCC5 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for ERCC5
- Novus Biologicals Antibodies for ERCC5
-
Cloud-Clone Corp. Antibodies for ERCC5
- Invitrogen Antibodies for ERCC5
- antibodies-online Antibodies for ERCC5: See all 70
- GeneTex ERCC5 antibody for ERCC5
-
Santa Cruz Biotechnology (SCBT) Antibodies for ERCC5
Protein Products
-
OriGene Purified Proteins for ERCC5
- Search Origene for MassSpec and Protein Over-expression Lysates for ERCC5
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-
Cloud-Clone Corp. Proteins for ERCC5
- antibodies-online Proteins for ERCC5: See all 3
- Search antibodies-online for peptides
- Search GeneTex for Proteins for ERCC5
Assay Products
- antibodies-online Kits for ERCC5: See all 5
No data available for DME Specific Peptides for ERCC5 Gene
Domains & Families for ERCC5 Gene
Gene Families for ERCC5 Gene
Protein Domains for ERCC5 Gene
Suggested Antigen Peptide Sequences for ERCC5 Gene
- GenScript: Design optimal peptide antigens:
-
- Xeroderma pigmentosum group G-complementing protein (ERCC5_HUMAN)
- Excision repair cross-complementing rodent repair deficiency, complementation group 5 (Xeroderma pigmentosum, complementation group G (Cockayne syndrome)) (Q5JUS1_HUMAN)
- Xeroderma pigmentosum complementation group G protein splice variant (Q9HD60_HUMAN)
- Xeroderma pigmentosum complementation group G protein splice variant (Q9NR54_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P28715- Family:
-
- Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
Function for ERCC5 Gene
Molecular function for ERCC5 Gene
- GENATLAS Biochemistry:
- excision repair cross-complementing rodent repair defect in CHO cells,complementation group 5,yeast RAD2 homolog (see XPG),deleted in metastatic prostate carcinomas
- UniProtKB/Swiss-Prot Function:
- Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too.
Enzyme Numbers (IUBMB) for ERCC5 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003690 | double-stranded DNA binding | IDA | 8090225 |
| GO:0003697 | single-stranded DNA binding | IDA | 12644470 |
| GO:0004518 | nuclease activity | IEA | -- |
| GO:0042803 | protein homodimerization activity | IPI | 10026181 |
Phenotypes for ERCC5 Gene
- MGI mutant phenotypes for ERCC5:
- inferred from 4 alleles
- GenomeRNAi human phenotypes for ERCC5:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for ERCC5 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ERCC5 gene
- Search ViGene Biosciences for ERCC5
CRISPR Products
-
OriGene CRISPR knockouts for ERCC5
-
Santa Cruz Biotechnology (SCBT) CRISPR for ERCC5
- GenScript: Design CRISPR guide RNA sequences for ERCC5
miRNA for ERCC5 Gene
- miRTarBase miRNAs that target ERCC5
miRNA Products
- Search ViGene Biosciences for ERCC5
Clone Products
- OriGene clones in human for ERCC5
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Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for ERCC5 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ERCC5 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ERCC5 gene
Flow Cytometry Products
No data available for Transcription Factor Targets and HOMER Transcription for ERCC5 Gene
Localization for ERCC5 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ERCC5 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytoskeleton | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005675 | colocalizes_with holo TFIIH complex | IDA | 11259578 |
Pathways & Interactions for ERCC5 Gene
More details on SuperPathways for ERCC5| Superpath | Contained pathways | ||
|---|---|---|---|
| 1 | Transcription-Coupled Nucleotide Excision Repair (TC-NER) | ||
| 2 | Nucleotide excision repair | ||
| 3 | p53 Pathway (RnD) | ||
| 4 | Chks in Checkpoint Regulation | ||
| 5 | DNA Double-Strand Break Repair |
.53
|
Pathways by source for ERCC5 Gene
7 Reactome pathways for ERCC5 Gene
1 KEGG pathway for ERCC5 Gene
1 R&D Systems pathway for ERCC5 Gene
2 Qiagen pathways for ERCC5 Gene
Interacting Proteins for ERCC5 Gene
Selected Interacting proteins:
P28715-ERCC5_HUMAN
ENSP00000347978
for ERCC5 Gene via
MINT
STRING
I2D
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006281 | DNA repair | IEA | -- |
| GO:0006293 | nucleotide-excision repair, preincision complex stabilization | TAS | -- |
| GO:0006296 | nucleotide-excision repair, DNA incision, 5-to lesion | TAS | -- |
| GO:0009650 | UV protection | IGI | 7510366 |
| GO:0033683 | nucleotide-excision repair, DNA incision | TAS | -- |
No data available for SIGNOR curated interactions for ERCC5 Gene
Drugs & Compounds for ERCC5 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| platinum | Pharma | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for ERCC5 Gene
mRNA/cDNA for ERCC5 Gene
- (1) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (9) Selected AceView cDNA sequences:
- (8) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ERCC5 Gene
- Excision repair cross-complementing rodent repair deficiency, complementation group 5:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for ERCC5
-
Santa Cruz Biotechnology (SCBT) CRISPR for ERCC5
- GenScript: Design CRISPR guide RNA sequences for ERCC5
miRNA Products
- Search ViGene Biosciences for ERCC5
Clone Products
- OriGene clones in human for ERCC5
- OriGene ORF clones in human,mouse,rat for ERCC5
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for ERCC5
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP7: |
Expression for ERCC5 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Heart (Cardiovascular System)
- Atrioventricular Node Cells Atrioventricular Node
-
Testis (Reproductive System)
- Leydig Cells Testis Interstitium
- Brain (Nervous System)
- Thyroid (Endocrine System)
- Intestine (Gastrointestinal Tract)
- Ovary (Reproductive System)
This gene is overexpressed in CD8 Tcells (16.3), Peripheral blood mononuclear cells (7.6), and Pancreas (7.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ERCC5 Gene
SOURCE GeneReport for Unigene cluster for ERCC5 Gene Hs.258429
- Elite partner
Primer Products
-
OriGene qPCR primer pairs and template standards for ERCC5
-
OriGene qPCR primer pairs for ERCC5
No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ERCC5 Gene
Orthologs for ERCC5 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | ERCC5 35 |
|
||
| ERCC5 36 |
|
OneToMany | |||
| dog (Canis familiaris) |
Mammalia | ERCC5 35 |
|
||
| BIVM 36 |
|
OneToMany | |||
| mouse (Mus musculus) |
Mammalia | Ercc5 35 |
|
||
| Ercc5 16 |
|
||||
| Ercc5 36 |
|
OneToMany | |||
| chimpanzee (Pan troglodytes) |
Mammalia | ERCC5 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ercc5 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 36 |
|
OneToMany | |
| chicken (Gallus gallus) |
Aves | ERCC5 35 |
|
||
| ERCC5 36 |
|
OneToMany | |||
| lizard (Anolis carolinensis) |
Reptilia | -- 36 |
|
OneToMany | |
| African clawed frog (Xenopus laevis) |
Amphibia | XPGC 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | ercc5 36 |
|
OneToMany | |
| fruit fly (Drosophila melanogaster) |
Insecta | mus201 37 |
|
|
|
| mus201 36 |
|
OneToMany | |||
| worm (Caenorhabditis elegans) |
Secernentea | gen-1 36 |
|
ManyToMany | |
| xpg-1 36 |
|
ManyToMany | |||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | RAD2 36 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 36 |
|
OneToMany |
- Species with no ortholog for ERCC5:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Paralogs for ERCC5 Gene
Paralogs for ERCC5 Gene
(1) SIMAP similar genes for ERCC5 Gene using alignment to 3 proteins:
Variants for ERCC5 Gene
| SNP ID | Clin | Chr 13 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| VAR_007732 | - | ||||
| VAR_007733 | Xeroderma pigmentosum complementation group G (XP-G) | ||||
| VAR_007734 | - | ||||
| VAR_014829 | - | ||||
| VAR_015280 | Xeroderma pigmentosum complementation group G (XP-G) |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv900972 | CNV | Loss | 21882294 |
| esv2661939 | CNV | Deletion | 23128226 |
Residual Variation Intolerance Score:
97.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
9.30;
88.25% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ERCC5 Gene
- Human Gene Mutation Database (HGMD)
- ERCC5
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ERCC5 Gene
Disorders for ERCC5 Gene
(14) MalaCards diseases for ERCC5 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| xeroderma pigmentosum, group g |
|
|
| cerebrooculofacioskeletal syndrome 3 |
|
|
| ercc5-related xeroderma pigmentosum |
|
|
| cockayne syndrome |
|
|
| xeroderma pigmentosum, variant type |
|
Search ERCC5 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
ERCC5_HUMAN- Xeroderma pigmentosum complementation group G (XP-G) [MIM:278780]: An autosomal recessive pigmentary skin disorder characterized by solar hypersensitivity of the skin, high predisposition for developing cancers on areas exposed to sunlight and, in some cases, neurological abnormalities. The skin develops marked freckling and other pigmentation abnormalities. Some XP-G patients present features of Cockayne syndrome, cachectic dwarfism, pigmentary retinopathy, ataxia, decreased nerve conduction velocities. The phenotype combining xeroderma pigmentosum and Cockayne syndrome traits is referred to as XP-CS complex. {ECO:0000269 PubMed:11228268, ECO:0000269 PubMed:11841555, ECO:0000269 PubMed:12060391, ECO:0000269 PubMed:7951246, ECO:0000269 PubMed:9096355}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Relevant External Links for ERCC5
No data available for Genatlas for ERCC5 Gene
Publications for ERCC5 Gene
- The human gene for Xeroderma pigmentosum complementation group G (XPG) maps to 13q33 by fluorescence in situ hybridization. (PMID: 8088806) Samec S. … Clarkson S.G. (Genomics 1994) 2 3 4 67
- Association and impact of XPG Asp 1104 His gene polymorphism in HIV 1 disease progression to AIDS among north Indian HIV seropositive individuals. (PMID: 19693700) Sobti R.C. … Wanchu A. (Mol. Biol. Rep. 2010) 3 23
- Polymorphisms in XRCC1 and XPG and response to platinum-based chemotherapy in advanced non-small cell lung cancer patients. (PMID: 19157633) Sun X. … Yingfeng Z. (Lung Cancer 2009) 3 23
- XPG mRNA expression levels modulate prognosis in resected non-small-cell lung cancer in conjunction with BRCA1 and ERCC1 expression. (PMID: 19289372) Bartolucci R. … Rosell R. (Clin Lung Cancer 2009) 3 23
- Sequential recruitment of the repair factors during NER: the role of XPG in initiating the resynthesis step. (PMID: 18079701) Mocquet V. … Egly J.M. (EMBO J. 2008) 3 23
Products for ERCC5 Gene
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- OriGene Purified Proteins for ERCC5
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- OriGene qPCR primer pairs for ERCC5
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- OriGene CRISPR knockouts for ERCC5
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- OriGene ORF clones in human,mouse,rat for ERCC5
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- Novus Biologicals Antibodies for ERCC5
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- Cloud-Clone Corp. Antibodies for ERCC5
- Cloud-Clone Corp. Proteins for ERCC5
- Addgene plasmids for ERCC5
- antibodies-online Antibodies for ERCC5: See all 70
- antibodies-online Kits for ERCC5: See all 5
- antibodies-online Proteins for ERCC5: See all 3
- Search antibodies-online for peptides
- GeneTex ERCC5 antibody for ERCC5
- Search GeneTex for Proteins for ERCC5
- ViGene Biosciences adenoviral particle packaged cDNA for ERCC5 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ERCC5 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ERCC5 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ERCC5 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ERCC5 gene
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- Santa Cruz Biotechnology (SCBT) Antibodies for ERCC5
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- Santa Cruz Biotechnology (SCBT) CRISPR for ERCC5
Sources for ERCC5 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
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