Aliases for ERC2 Gene
External Ids for ERC2 Gene
Previous GeneCards Identifiers for ERC2 Gene
This gene encodes a protein that belongs to the Rab3-interacting molecule (RIM)-binding protein family. Members of this protein family form part of the cytomatrix at the active zone (CAZ) complex and function as regulators of neurotransmitter release. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
GeneCards Summary for ERC2 Gene
ERC2 (ELKS/RAB6-Interacting/CAST Family Member 2) is a Protein Coding gene. Among its related pathways are Degradation of the extracellular matrix and DREAM Repression and Dynorphin Expression. An important paralog of this gene is ERC1.
UniProtKB/Swiss-Prot for ERC2 Gene
Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ.