ERBB2IP Gene
protein-coding GIFtS: 60
GCID: GC05P065258
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|
erbb2 interacting protein(Previous name: erbb2-interacting protein )
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Aliases
for ERBB2IP gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Erbb2 Interacting Protein1 2 | | Densin-180-Like Protein2 3 | | ERBIN1 2 3 5 | | Protein LAP22 | | LAP21 2 3 | | Erbin3 | | Erbb2-Interacting Protein1 3 | | KIAA12253 |
Export aliases for ERBB2IP gene to outside databasesPrevious GC identifers: GC05P065374 GC05P066760 GC05P065192 GC05P065238 GC05P065225 GC05P062180 |
Summaries
for ERBB2IP gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ERBB2IP:
This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulatesERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Rafinteraction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.(provided by RefSeq, Nov 2011)
UniProtKB/Swiss-Prot: LAP2_HUMAN, Q96RT1Function: Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated 'Tyr-1248' ofreceptor ERBB2, it may contribute to stabilize this unphosphorylated state
Gene Wiki entry for ERBB2IP (Erbin)
|
Genomic Views
for ERBB2IP gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_006713.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ERBB2IP gene promoter:
AhR NF-1 NF-1/L AML1a HOXA3 Arnt FOXO4 FOXO1a En-1 FOXO1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ERBB2IP
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ERBB2IP |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q12.3 Ensembl cytogenetic band: 5q12.3 HGNC cytogenetic band: 5p14.3-q12.3ERBB2IP Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P065258: view genomic region
(about GC identifiers)
Start:
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65,222,303 bp from pter |
End:
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65,378,377 bp from pter |
Size:
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156,075 bases |
Orientation:
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plus strand |
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Proteins
for ERBB2IP gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: LAP2_HUMAN, Q96RT1 (See
protein sequence)Recommended Name: Protein LAP2 Size: 1412 amino acids; 158298 Da
Subunit: Interacts with ERBB2, BPAG1 and ITGB4. May favor the localization of ERBB2, by restricting its presence to thebasolateral membrane of epithelial cells. Also found to interact with ARVCF and delta catenin. Interacts (viaC-terminus) with DST Isoform 3 (via N-terminus)
Subcellular location: Cell junction, hemidesmosome. Nucleus membrane (By similarity). Note=Found in hemidesmosomes,which are cell-substrate adhesion complexes in stratified epithelia. In transfected cells, either diffuselydistributed over the cytoplasm or concentrated at the basolateral membrane. Colocalizes with the adrenergic receptors,ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes (By similarity)
Sequence caution: Sequence=AAH50692.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-Asequence; Sequence=BAA91538.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
6 PDB 3D structures from  and Proteopedia  for ERBB2IP:1MFG (3D)
1MFL (3D)
1N7T (3D)
2H3L (3D)
2QBW (3D)
3CH8 (3D)
Secondary accessions: A0AVR1 B4E3F1 B7ZLV9 E9PCR8 Q1RMD0 Q86W38 Q9NR18 Q9NW48 Q9ULJ5Alternative splicing: 8 isoforms: Q96RT1-1 Q96RT1-2 Q96RT1-3 Q96RT1-4 Q96RT1-5 Q96RT1-6 Q96RT1-7 Q96RT1-8 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ERBB2IP: NX_Q96RT1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96RT1
ERBB2IP Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (6 alternative transcripts):
NP_001006600.1 NP_001240626.1 NP_001240627.1 NP_001240628.1 NP_001240630.1 NP_061165.1
ENSEMBL proteins: ENSP00000284037 ENSP00000370330 ENSP00000397833 ENSP00000370325 ENSP00000422766 ENSP00000426632 ENSP00000422015 ENSP00000425728 ENSP00000423959 ENSP00000370326 ENSP00000370323 ENSP00000370322 Reactome Protein details: Q96RT1
Human Recombinant Protein Products for ERBB2IP:
Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8): About this table
ERBB2IP for ontologies About GeneDecksing
ERBB2IP Antibody Products:
Assay Products for ERBB2IP: |
Protein
Domains /
Families
for ERBB2IP gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ERBB2IP for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96RT1ProtoNet protein and cluster: Q96RT1 1 Blocks protein family: IPB001478 PDZ/DHR/GLGF domain
UniProtKB/Swiss-Prot: LAP2_HUMAN, Q96RT1Similarity: Belongs to the LAP (LRR and PDZ) protein familySimilarity: Contains 17 LRR (leucine-rich) repeatsSimilarity: Contains 1 PDZ (DHR) domain |
Function
for ERBB2IP gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: LAP2_HUMAN, Q96RT1Function: Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated 'Tyr-1248' ofreceptor ERBB2, it may contribute to stabilize this unphosphorylated state Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
ERBB2IP for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for ERBB2IP:
3 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Erbb2ip):
ERBB2IP for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Erbb2iptm1Line for ERBB2IP
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ERBB2IP (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ERBB2IP (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ERBB2IP (NM_018695) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ERBB2IP | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ERBB2IP |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ERBB2IP |
|
Pathways & Interactions
for ERBB2IP gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | | | 2 | Alpha6-Beta4 Integrin Signaling Pathway | | | 3 | TGF-beta Receptor Signaling Pathway | | | 4 | Signaling by FGFR | | | 5 | Signaling by GPCR | |
Pathway sources
See GeneCards unified pathways
Show all pathways
4  BioSystems Pathways for ERBB2IP
2 
Reactome Pathways for ERBB2IP
1 
Kegg Pathway (Kegg details for ERBB2IP):
ERBB2IP for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ERBB2IP
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/139 Interacting proteins for ERBB2IP (Q96RT12, 3 ENSP000003703304) via UniProtKB, MINT, STRING, and/or I2D (see all 139)About this table
Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table
ERBB2IP for ontologies About GeneDecksing
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Drugs & Compounds
for ERBB2IP gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ERBB2IP for compounds About GeneDecksing
 Browse Tocris compounds for ERBB2IP
2 Novoseek chemical compound relationships for ERBB2IP gene About this table
Search CenterWatch for drugs/clinical trials and news about ERBB2IP / LAP2
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Transcripts
for ERBB2IP gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ERBB2IP gene (6 alternative transcripts): NM_001006600.2 NM_001253697.1 NM_001253698.1 NM_001253699.1 NM_001253701.1 NM_018695.3 Unigene Cluster for ERBB2IP: Erbb2 interacting protein Hs.740465 [show with all ESTs]Unigene Representative Sequence: NM_00125369918/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19): ENST00000284037(uc003juk.2 uc011cqx.2 uc003jui.2 uc003jul.2 uc011cqy.2 uc003juj.2 uc011cqz.2 uc010iwx.2)
ENST00000380943 ENST00000507490 ENST00000416865 ENST00000380938 ENST00000511297
ENST00000506030 ENST00000508515 ENST00000507128 ENST00000515185 ENST00000511671
ENST00000503913 ENST00000512354 ENST00000505822 ENST00000509946 ENST00000506744
ENST00000380939 ENST00000380936
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ERBB2IP (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ERBB2IP (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ERBB2IP (NM_018695) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ERBB2IP | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ERBB2IP |
Additional cDNA sequence: AB033051.2 AF263744.1 AF276423.1 AK001180.1 AK026757.1 AK027077.1 AK074288.1 AK295708.1 AK304693.1 BC050692.1 BC115012.1 BC115015.1 BC126464.1 BC144075.1 14 DOTS entries: DT.100781598 DT.100781595 DT.117180 DT.100781600 DT.95371575 DT.441994 DT.97794126 DT.100855213 DT.120857944 DT.120857948 DT.120857965 DT.95347826 DT.95371692 DT.91740847 24/298 AceView cDNA sequences (see all 298): BE464283 N51334 AW014276 AA311168 AI609780 CN483679 AI433705 AA504086 AA984483 BC050692 BF431503 AL138373 BG287698 AA298158 AL706734 CA443650 AI084006 AL707952 AI419373 BF196604 N25214 AI129162 AI671892 AW297799
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for ERBB2IP About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b | · | 21c | ^ | 22 | ^ | 23 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 24 | ^ | 25 | ^ | 26a | · | 26b | ^ | 27a | · | 27b | · | 27c |
|---|
|
| SP1: | | | | | - | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | |
| SP3: | - | | | | - | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ERBB2IP
|
Expression
for ERBB2IP gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ERBB2IP expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTTATTTGGA
About this image
See ERBB2IP Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ERBB2IP
SOURCE GeneReport for Unigene cluster: Hs.740465
UniProtKB/Swiss-Prot: LAP2_HUMAN, Q96RT1Tissue specificity: Highly expressed in brain, heart, kidney, muscle and stomach, followed by liver, spleen andintestine
SABiosciences Expression via Pathway-Focused PCR Array including ERBB2IP: | Inflammatory Response & Autoimmunity 384HT in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ERBB2IP
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ERBB2IP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ERBB2IP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ERBB2IP | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ERBB2IP |
Orthologs
for ERBB2IP gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ERBB2IP gene from 6/18 species (see all 18) About this table
ENSEMBL Gene Tree for ERBB2IP (if available)
TreeFam Gene Tree for ERBB2IP (if available) |
Paralogs
for ERBB2IP gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ERBB2IP gene
- LRRC72 LRRC22 MFHAS12 LRRC182 LRRC302 LRRC12 PIDD2 LRRIQ42
- SCRIB2 SHOC22 LRRD12 LRRC10B2 LRRC392 LRRC402 LRRC102
10 SIMAP similar genes for ERBB2IP using alignment to 6 protein entries: LAP2_HUMAN (see all proteins):LRRD1 LRRC7 LRRC1 TJP2 LRRC8B RSU1
LRIG3 TAX1BP3 DLG4 LRRC28
ERBB2IP for paralogs About GeneDecksing
|
Genomic Variants
for ERBB2IP gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ERBB2IP (65222303 - 65378377 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 15 variations for ERBB2IP
8 CNVs: 99163 93082 93083 4446 69075 93084 80943 64224
7 Indels: 46910 42830 51724 40761 46911 27980 62382 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ERBB2IP |
|
Disorders
/ Diseases
for ERBB2IP gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ERBB2IP for disorders About GeneDecksing
OMIM gene information: 606944
OMIM disorders: --
10  diseases for ERBB2IP: About MalaCardsepidermolysis bullosa dystrophica epidermolysis bullosa arteriovenous malformation bullous pemphigoid
crohn's disease colon carcinoma cervical cancer cervicitis
breast cancer carcinoma
1 Novoseek disease relationship for ERBB2IP gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tumors |
0 |
7 |
19289088 (2), 17164780 (2), 16595147 (1) |
Human Genome Epidemiology (HuGE) Navigator: ERBB2IP (1 document)
Export disorders for ERBB2IP gene to outside databases
|
Publications
for ERBB2IP gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ERBB2IP gene, integrated from 9 sources (see all 81):
(articles sorted by number of sources associating them with ERBB2IP) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- ERBIN: a basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor. (PubMed id 10878805)1, 2, 3, 9 Borg J.-P....Birnbaum D. (2000)
- Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10574462)1, 2, 3 Nagase T.... Ohara O. (1999)
- The hemidesmosomal protein bullous pemphigoid antigen 1 and the integrin beta 4 subunit bind to ERBIN. Molecular cloning of multiple alternative splice variants of ERBIN and analysis of their tissue expression. (PubMed id 11375975)1, 2, 9 Favre B.... Borradori L. (2001)
- The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of delta-catenin and ARVCF. (PubMed id 11821434)1, 2, 9 Laura R.P.... Lasky L.A. (2002)
- Origins of PDZ domain ligand specificity. Structure determination and mutagenesis of the Erbin PDZ domain. (PubMed id 12446668)1, 2, 9 Skelton N.J.... Sidhu S.S. (2003)
- Comparative structural analysis of the erbin PDZ domain and the first PDZ domain of ZO-1. Insights into determinants of PDZ domain specificity. (PubMed id 16737969)1, 2, 9 Appleton B.A.... Wiesmann C. (2006)
- Novel mode of ligand recognition by the Erbin PDZ domain. (PubMed id 12444095)1, 2, 9 Birrane G.... Ladias J.A. (2003)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
|
External Searches for ERBB2IP gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ERBB2IP gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ERBB2IP gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ERBB2IP gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ERBB2IP gene:
Search GeneIP for patents involving ERBB2IP
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ERBB2IP gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ERBB2IP | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ERBB2IP | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ERBB2IP | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ERBB2IP | | OriGene 3'-UTR Clone for ERBB2IP | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ERBB2IP | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ERBB2IP | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ERBB2IP | | OriGene Custom Protein Services for ERBB2IP | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ERBB2IP | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ERBB2IP | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ERBB2IP | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ERBB2IP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ERBB2IP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ERBB2IP |
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| | | | Search Tocris compounds for ERBB2IP |
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 | | | ERBB2IP Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ERBB2IP |
|  |  |  |  | | | | Search ThermoFisher Antibodies for ERBB2IP |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ERBB2IP |
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