Aliases for ERAS Gene
External Ids for ERAS Gene
Previous HGNC Symbols for ERAS Gene
Previous GeneCards Identifiers for ERAS Gene
This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012]
GeneCards Summary for ERAS Gene
ERAS (ES Cell Expressed Ras) is a Protein Coding gene. Diseases associated with ERAS include median neuropathy and intracranial abscess. GO annotations related to this gene include GTP binding. An important paralog of this gene is HRAS.
UniProtKB/Swiss-Prot for ERAS Gene
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells (By similarity).