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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ERAL1 Gene

protein-coding   GIFtS: 53
GCID: GC17P027182

Era-Like 12S Mitochondrial RRNA Chaperone 1

(Previous names: Era (E. coli G-protein homolog)-like 1, Era G-protein-like...)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Era-Like 12S Mitochondrial RRNA Chaperone 11 2     ERA2
Era (E. Coli G-Protein Homolog)-Like 11 2     ERAL1A2
Conserved ERA-Like GTPase2 3     HERA-A2
CEGA2 3     HERA-B2
ERA-W2 3     Era G-Protein-Like 12
H-ERA2 3     GTP-Binding Protein Era Homolog2
ERA-Like Protein 12 3     GTPase Era, Mitochondrial2
hERA2 3     GTPase, Human Homolog Of E. Coli Essential Cell Cycle Protein Era2
Era G-Protein-Like 1 (E. Coli)1     HERA3

External Ids:    HGNC: 34241   Entrez Gene: 262842   Ensembl: ENSG000001325917   OMIM: 6074355   UniProtKB: O756163   

Export aliases for ERAL1 gene to outside databases

Previous GC identifers: GC17P027027 GC17P029081 GC17P027327 GC17P024206 GC17P023390


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ERAL1 Gene: 
ERAL1 (Era-like 12S mitochondrial rRNA chaperone 1) is a protein-coding gene. Diseases associated with ERAL1 include alopecia areata, and hepatitis a. GO annotations related to this gene include RNA binding and rRNA binding.

UniProtKB/Swiss-Prot: ERAL1_HUMAN, O75616
Function: Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically
binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop
region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal
small subunit assembly




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.2  NT_010799.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ERAL1 gene promoter:
         ER-alpha   AREB6   C/EBPbeta   p53   AML1a   CUTL1   ZIC2/Zic2   Roaz   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidERAL1 promoter sequence
   Search SABiosciences Chromatin IP Primers for ERAL1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ERAL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q11.2   Ensembl cytogenetic band:  17q11.2   HGNC cytogenetic band: 17q11.2

ERAL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ERAL1 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P027182:  view genomic region     (about GC identifiers)

Start:
27,181,956 bp from pter      End:
27,188,085 bp from pter
Size:
6,130 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ERAL1_HUMAN, O75616 (See protein sequence)
Recommended Name: GTPase Era, mitochondrial precursor  
Size: 437 amino acids; 48350 Da
Subcellular location: Mitochondrion matrix. Mitochondrion inner membrane; Peripheral membrane protein.
Note=Localizes on the matrix side on the mitochondrial inner membrane
Sequence caution: Sequence=AAG12978.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: B3KN21 C9JEC6 O75617 Q8WUY4 Q96LE2 Q96TC0
Alternative splicing: 2 isoforms:  O75616-1   O75616-2   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for ERAL1: NX_O75616

Explore proteomics data for ERAL1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O75616

  • ERAL1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ERAL1 Protein Expression
    REFSEQ proteins: NP_005693.1  
    ENSEMBL proteins: 
     ENSP00000254928   ENSP00000396125   ENSP00000464607   ENSP00000464402   ENSP00000467860  

    Human Recombinant Protein Products for ERAL1: 
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    Novus Biologicals ERAL1 Protein
    Novus Biologicals ERAL1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ERAL1 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005743mitochondrial inner membrane IEA--
    GO:0005759mitochondrial matrix IDA--
    GO:0016021integral to membrane ----

    ERAL1 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for ERAL1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5/6 InterPro protein domains (see all 6):
     IPR009019 KH_prok-type
     IPR005662 GTP-bd_Era
     IPR005225 Small_GTP-bd_dom
     IPR027417 P-loop_NTPase
     IPR006073 GTP_binding_domain

    Graphical View of Domain Structure for InterPro Entry O75616

    ProtoNet protein and cluster: O75616

    2 Blocks protein domains:
    IPB002917 GTP-binding protein
    IPB006073 GTP1/OBG GTP-binding protein family signature


    UniProtKB/Swiss-Prot: ERAL1_HUMAN, O75616
    Similarity: Belongs to the Era/MnmE GTP-binding protein family. Era subfamily
    Similarity: Contains 1 G (guanine nucleotide-binding) domain
    Similarity: Contains 1 KH type-2 domain


    ERAL1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ERAL1_HUMAN, O75616
    Function: Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically
    binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop
    region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal
    small subunit assembly

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding NAS--
    GO:0003924GTPase activity ----
    GO:0005525GTP binding NAS--
    GO:0015093ferrous iron transmembrane transporter activity ----
    GO:0019843rRNA binding IDA--
         
    ERAL1 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for ERAL1:
     Decreased cilium length  Decreased cilium length after   Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ERAL1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ERAL1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ERAL1 
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    5 QIAGEN miScript miRNA Assays for microRNAs that regulate ERAL1:
    hsa-miR-1266 hsa-miR-610 hsa-miR-3125 hsa-miR-3916 hsa-miR-646
    SwitchGear 3'UTR luciferase reporter plasmidERAL1 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ERAL1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ERAL1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Integrated Breast Cancer Pathway
    Integrated Breast Cancer Pathway


    1 BioSystems Pathway for ERAL1
        Integrated Breast Cancer Pathway



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ERAL1

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/801 Interacting proteins for ERAL1 (O756162, 3 ENSP000002549284) via UniProtKB, MINT, STRING, and/or I2D (see all 801)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ICT1Q141972, 3, ENSP000003015854MINT-8079030 I2D: score=1 STRING: ENSP00000301585
    CDC5LQ994592, ENSP000003605324MINT-7947479 STRING: ENSP00000360532
    HSPD1P108092MINT-8079030 MINT-7947479
    TFB1MQ8WVM02, ENSP000003561344MINT-8079030 STRING: ENSP00000356134
    TMLHEQ9NVH63I2D: score=5 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000028ribosomal small subunit assembly IMP--
    GO:0007264small GTPase mediated signal transduction ----
    GO:0015684ferrous iron transport ----

    ERAL1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ERAL1

    1 HMDB Compound for ERAL1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--

    Search CenterWatch for drugs/clinical trials and news about ERAL1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ERAL1 gene: 
    NM_005702.2  

    Unigene Cluster for ERAL1:

    Era G-protein-like 1 (E. coli)
    Hs.3426  [show with all ESTs]
    Unigene Representative Sequence: BX537542
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000254928(uc002hcy.1 uc002hcz.1) ENST00000412138(uc002hcx.1)
    ENST00000578001 ENST00000461894 ENST00000580917 ENST00000577942 ENST00000471992(uc002hda.1)
    ENST00000583487
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ERAL1
    5 QIAGEN miScript miRNA Assays for microRNAs that regulate ERAL1:
    hsa-miR-1266 hsa-miR-610 hsa-miR-3125 hsa-miR-3916 hsa-miR-646
    SwitchGear 3'UTR luciferase reporter plasmidERAL1 3' UTR sequence
    Inhib. RNA
    Products:
         
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ERAL1
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    OriGene clones in human, mouse for ERAL1 (see all 8)
    OriGene ORF clones in mouse, rat for ERAL1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ERAL1 (NM_005702)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ERAL1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ERAL1
    Sirion Biotech Customized lentivirus for stable overexpression of ERAL1 
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    OriGene qPCR primer pairs and template standards for ERAL1
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ERAL1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ERAL1

    Additional mRNA sequence: 

    AB049388.1 AF082657.1 AF082658.1 AK023342.1 AY007435.1 BC019094.2 BX537542.1 

    14 DOTS entries:

    DT.95262445  DT.453317  DT.100757764  DT.97847786  DT.120891892  DT.100885111  DT.100029293  DT.100885106 
    DT.86854990  DT.100727289  DT.120891874  DT.120891915  DT.91760690  DT.91760692 

    24/401 AceView cDNA sequences (see all 401):

    AI936052 CR600900 BE206995 BG325844 CR614207 BU502559 BU956992 BP350163 
    BC019094 CR611953 CR609444 AA195006 BM712482 BU553826 T32992 BQ648204 
    AA887140 BM843949 BQ068079 AI336172 BM842728 R19122 D79048 AI720327 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for ERAL1 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10
    SP1:                          -           -     -                                                   
    SP2:                          -           -     -                       -     -                     
    SP3:                          -           -     -                                                   
    SP4:                          -     -     -     -                                                   
    SP5:                                                                                                


    ECgene alternative splicing isoforms for ERAL1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ERAL1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AACACTGACT
    ERAL1 Expression
    About this image


    See ERAL1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ERAL1

    SOURCE GeneReport for Unigene cluster: Hs.3426
        SABiosciences Custom PCR Arrays for ERAL1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ERAL1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ERAL1 gene from 7/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Eral11 , 5 Era (G-protein)-like 1 (E. coli)1, 5 82.91(n)1
    78.26(a)1
      11 (46.74 cM)5
    578371  NM_022313.21  NP_071708.21 
     780733765 
    chicken
    (Gallus gallus)
    Aves ERAL11 Era G-protein-like 1 (E. coli) 61.58(n)
    58.62(a)
      374084  NM_204239.1  NP_989570.1 
    lizard
    (Anolis carolinensis)
    Reptilia ERAL16
    Uncharacterized protein
    70(a)
    1 ↔ 1
    GL344494.1(30310-32155)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.119032 Transcribed sequence with weak similarity to protein more 74.58(n)    CF222733.1 
    zebrafish
    (Danio rerio)
    Actinopterygii eral11 Era G-protein-like 1 (E. coli) 57.03(n)
    54.32(a)
      569087  NM_001128747.1  NP_001122219.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG74881 CG7488 45.85(n)
    32.69(a)
      41597  NM_141991.2  NP_650248.1 
    worm
    (Caenorhabditis elegans)
    Secernentea E02H1.21 Protein E02H1.2 41.15(n)
    30(a)
      174508  NM_063659.1  NP_496060.1 


    ENSEMBL Gene Tree for ERAL1 (if available)
    TreeFam Gene Tree for ERAL1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/160 SNPs in ERAL1 are shown (see all 160)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs3715426401,2
    C--27180212(+) TGTCT-/AAAAAAA 1 -- us2k10--------
    rs1485257311,2
    C--27180320(+) GAGGCC/TGTAGT 1 -- us2k10--------
    rs604499321,2
    C--27180343(+) CACCAA/CTGCAC 1 -- us2k10--------
    rs1893034091,2
    --27180376(+) GACCCC/TGTCTC 1 -- us2k10--------
    rs99150531,2
    C,F,H--27180615(+) tactgT/Cattgt 1 -- us2k19Minor allele frequency- C:0.02NS EA NA WA 1190
    rs1169000051,2
    F--27180653(+) TAGAGA/GTGGGG 1 -- us2k11Minor allele frequency- G:0.01NA 120
    rs47954671,2
    C,F,A,H--27180784(+) tgtgcC/Ttgtag 1 -- us2k121Minor allele frequency- T:0.19NS EA NA WA 2328
    rs343932471,2
    C--27180960(+) GTTTC-/TTTTTT 1 -- us2k12Minor allele frequency- T:0.25NA 4
    rs1156294131,2
    --27180964(+) CTTTTC/TTTTTT 1 -- us2k10--------
    rs1817243141,2
    --27181151(+) AGAGAA/CCGGGT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ERAL1 (27181956 - 27188085 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for ERAL1: --
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607435    OMIM disorders: --

    7 diseases for ERAL1:    About MalaCards
    alopecia areata    hepatitis a    alopecia    pneumonia
    tuberculosis    hepatitis    breast cancer


    ERAL1 for disorders           About GeneDecksing


    Export disorders for ERAL1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ERAL1 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with ERAL1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human ERAL1 is a mitochondrial RNA chaperone involved in the assembly of the 28S small mitochondrial ribosomal subunit. (PubMed id 20604745)1, 2, 3 Dennerlein S....Lightowlers R.N. (2010)
    2. Isolation and preliminary characterization of the human and mouse homologues of the bacterial cell cycle gene era. (PubMed id 10945472)1, 2, 3 Britton R.A....Lupski J.R. (2000)
    3. Mammalian homologue of E. coli Ras-like GTPase (ERA) is a possible apoptosis regulator with RNA binding activity. (PubMed id 11733036)1, 2, 9 Akiyama T....Inoue J. (2001)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. An unappreciated role for RNA surveillance. (PubMed id 14759258)1, 2 Hillman R.T.... Brenner S.E. (2004)
    7. p32/gC1qR is indispensable for fetal development and m itochondrial translation: importance of its RNA-binding ability. (PubMed id 22904065)1 Yagi M....Kang D. (2012)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    9. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
    10. Biochemical and phosphoproteomic analysis of the helix -loop-helix protein E47. (PubMed id 22354994)1 Teachenor R....Murre C. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26284 HGNC: 3424 AceView: ERAL1 Ensembl:ENSG00000132591 euGenes: HUgn26284
    ECgene: ERAL1 H-InvDB: ERAL1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ERAL1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ERAL1 gene:
    Search GeneIP for patents involving ERAL1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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