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ERAF Gene

protein-coding GIFtS: 53

GC16P031446

erythroid associated factor
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
AHSP ^¹, ², ⁵
EDRF ^¹, ², ³, ⁵

Descriptions
Erythroid differentiation-related factor ^², ³
Erythroid-associated factor ^³
alpha hemoglobin stabilising protein ^²
erythroid associated factor ^²
erythroid differentiation associated factor ^²

External Ids
HGNC: 18075¹
Entrez Gene: 51327²
UniProtKB: Q9NZD4³
Ensembl: ENSG00000169877⁷

Search outside databases for aliases for ERAF gene

Previous GC identifers: GC16P030620 GC16P032035 GC16P031536 GC16P031575

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: AHSP_HUMAN, Q9NZD4

Function: Act as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal

erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is

predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia

Gene Wiki entry for ERAF

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ERAF gene

Entrez Gene cytogenetic band: 16p11.2 Ensembl cytogenetic band: 16p11.2 HGNC cytogenetic band: 16p11.1

ERAF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 16 GeneLoc Exon Structure

GeneLoc location for GC16P031446: (about GC identifiers)

Start:	31,446,680 bp from pter
End:	31,447,625 bp from pter
Size:	946 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000016.8 NT_010393.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: AHSP_HUMAN, Q9NZD4 (See protein sequence)

Recommended Name: Alpha-hemoglobin-stabilizing protein

Size: 102 amino acids; 11840 Da

Subunit: Monomer. Forms an heterodimer with free alpha-hemoglobin. Does not bind beta-hemoglobin

nor alpha(2)beta(2) hemoglobin A

Subcellular location: Cytoplasm

PDB structures from and Proteopedia :

1W09 (3D)

1W0A (3D)

1W0B (3D)

1XZY (3D)

1Y01 (3D)

1Z8U (3D)

Secondary accessions: Q8TD01

REFSEQ proteins: NP_057717.1

ENSEMBL proteins:

ENSP00000307199

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Ahsp)
	Human Recombinant Proteins from Abnova (ERAF)

OriGene Purified Recombinant Human Protein: ERAF

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0005833	hemoglobin complex	NAS	12066189

About this table

Antibodies for ERAF:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Ahsp), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (ERAF)
	Novus Biologicals Antibodies for ERAF

Assays for ERAF:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q9NZD4

ProtoNet protein and cluster: Q9NZD4

UniProtKB/Swiss-Prot: AHSP_HUMAN, Q9NZD4

Similarity: Belongs to the AHSP family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ERAF)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ERAF)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_016633

Applied Biosystems Silencer® siRNAs for ERAF

Sigma-Aldrich siRNA for ERAF

Sigma-Aldrich shRNA for ERAF

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for ERAF
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_016633
Myc/DDK tagged cDNA clone in CMV expression vector: NM_016633
untagged cDNA clone in CMV expression vector: NM_016633

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_016633

UniProtKB/Swiss-Prot: AHSP_HUMAN, Q9NZD4

Function: Act as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal

erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is

predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia

Induction: By GATA-1 during erythroid maturation

5 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Eraf):

cellular

hematopoietic system

immune system

lethality-prenatal/perinatal

skin/coat/nails

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0030492	hemoglobin binding	NAS	12066189
GO:0051082	unfolded protein binding	NAS	12066189

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for ERAF

5/11 Interacting proteins for ERAF (ENSP00000307199³ Q9NZD4^{1, 2}) via UniProtKB, MINT, and/or STRING (see all 11 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
HBA1	P69905¹	STRING (score=.96) EBI-720250, EBI-714680
GATA1	ENSP00000365858³	STRING (score=.996)
NGB	ENSP00000298352³	STRING (score=.948)
HBA2	ENSP00000251595³	STRING (score=.943)
HBZ	ENSP00000252951³	STRING (score=.943)

About this table

4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006457	protein folding	IEA	--
GO:0020027	hemoglobin metabolic process	NAS	12066189
GO:0030097	hemopoiesis	NAS	12066189
GO:0050821	protein stabilization	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for ERAF
10/29 Novoseek chemical compound relationships for ERAF gene (see all 29 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
nitric oxide	77.67	306	8107883 (4), 7743332 (4), 15714750 (4), 8845443 (2) (see all 99)
cgmp	76.80	44	1311528 (4), 1868189 (2), 1794204 (2), 1318427 (2) (see all 27)
guanylate	76.07	22	1681884 (2), 1868189 (2), 8447442 (1), 8638522 (1) (see all 18)
dbnbs	61.00	2	8282215 (1)
methylene	57.95	14	1629068 (1), 8447442 (1), 2162879 (1), 1991651 (1) (see all 10)
thromboxane a2	52.75	11	1296206 (3), 1318427 (2), 8044917 (1), 10072715 (1) (see all 6)
superoxide	51.81	11	7685446 (1), 1658794 (1), 8461525 (1), 1309423 (1) (see all 6)
adp	42.82	12	8017760 (2), 1697386 (1), 9402468 (1), 9515109 (1) (see all 7)
thromboxane	40.00	5	17048133 (1), 1756024 (1), 1717768 (1), 1395116 (1)
calcium	37.97	50	1376838 (4), 2381766 (3), 7947609 (3), 1794204 (2) (see all 23)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ERAF)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ERAF)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_016633

Sigma-Aldrich siRNA for ERAF

Sigma-Aldrich shRNA for ERAF

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_016633

REFSEQ mRNAs for ERAF gene:

NM_016633.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_016633

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_016633
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_016633
                                 untagged cDNA clone in CMV expression vector: NM_016633

Additional cDNA sequence:

AF112995.1 AF147435.1 AF208865.1 AF364517.1 BC035842.1 CR599801.1

3 DOTS entries:

DT.100033632 DT.95130651 DT.95130637

24/92 AceView cDNA sequences (see all 92 ):

N64110 AI370497 CR599801 BU658045 BG940214 BG943419 H52289 BG944377

AF208865 BX422380 BG940046 C21225 BG942798 BQ189659 T53200 BC035842

BG942782 BG939943 CK300787 H52526 BG943368 H94872 BG943964 R91558

highest scoring ESTs for ERAF:

H94872 AA033701 AA033702 AA092294 AA328577 AA338152 AA339867 AA723496 AF208865 AF364517

Unigene Cluster for ERAF:

Erythroid associated factor

Hs.274309 [show with all ESTs]

Unigene Representative Sequence: BI834180

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for ERAF

ExUns:	1a	·	1b	^	2	^	3a	·	3b
SP1:
SP2:

About this scheme

ECgene alternative splicing isoforms for ERAF

1 Ensembl transcript including schematic representation:

ENST00000302312

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

ERAF expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ERAF

¹ / ² / ³

3 probe-sets matching ERAF gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
55072_at²^{, 3}	U95-B	1	1.00	1.00	1.00	1.00	H94872	1.00	1.00	1.00	1
219672_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_016633	0.60	1.00	0.82	1
219672_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks ERAF for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TCCTTAGGCT

SOURCE GeneReport for Unigene cluster: Hs.274309
UniProtKB/Swiss-Prot: AHSP_HUMAN, Q9NZD4
Tissue specificity: Expressed in blood and bone marrow

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ERAF gene from 4 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
chimpanzee (Pan troglodytes)	ERAF¹	--	erythroid associated factor	100(n) 100(a)	454073 XM_001159573.1 XP_001159573.1
cow (Bos taurus)	ERAF¹	--	erythroid associated factor	81.68(n) 70.33(a)	338381 NM_177522.2 NP_803488.1
rat (Rattus norvegicus)	Eraf¹	--	erythroid associated factor	75.82(n) 66.67(a)	293522 XM_215059.3 XP_215059.1
mouse (Mus musculus)	Eraf⁵	--	erythroid associated factor	--	BC110627

About this table Species with no ortholog for ERAF

ENSEMBL Gene Tree for ERAF

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/29 NCBI SNPs in ERAF are shown (see all 29 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 22)

AB	SNP ID	Valid	Chr 16 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs4499252^1,2	A,C,F,H	31446483(+)	`ACTGAA/GATATG`	1	--	ng5¹		4		EU EA WA	416
	rs10843^1,2	A,C,F,H	31447531(+)	`GCCCCT/CCCTCT`	1	--	ut3¹ ese³ trp³		4		EU EA WA	412
	rs8046452^1,2	A,C,F	31446240(+)	`CCACAC/TGCTTA`	1	--	ng5¹		4		NA EA	362
	rs4319784^1,2	A,C	31446683(+)	`TCTTAA/GGCTGA`	1	--	ng5¹ ese³		0	--	--	--	--
	rs36018996^1,2	C,F	31447502(-)	`GGAGGG/TCGGTG`	1	P/T	mis¹		5		NA EU EA WA	498
--	rs7202020^1,2	A	31445156(+)	`ATACTA/GTATGA`	1	--	ng5¹ tfbs³		0	--	--	--	--
	rs10920^1,2	H	31447338(+)	`CTGGAT/AGAACT`	1	K/M	mis¹		5		MN EU EA WA	580
--	rs7203199^1,2	A	31445075(+)	`TGTGTC/GCACTG`	1	--	ng5¹		0	--	--	--	--
--	rs9921592^1,2	A	31445960(+)	`AAAGAA/GGAAAA`	1	--	ng5¹ trp³		0	--	--	--	--
	rs17677^1,2	A,C,F,H	31447435(+)	`ACTCTG/TGCCAA`	1	L/L	syn¹ ese³		6		MN EU EA WA NA	672

About this table

HapMap Linkage Disequilibrium images for ERAF (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 605821

10/35 Novoseek disease relationships for ERAF gene (see all 35 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
vasospasm	64.15	5	9402468 (1), 9515109 (1), 1717775 (1), 7568903 (1) (see all 5)
vascular dilation	58.05	2	1928200 (1), 1343264 (1)
atherosclerosis	53.56	20	7568903 (2), 2045172 (1), 1868189 (1), 8222147 (1) (see all 15)
coronary vasospasm	49.18	1	11543600 (1)
vascular diseases	41.61	5	14650203 (2), 1868189 (1), 1921472 (1)
hypercholesterolemia	38.70	2	7568903 (1), 9340578 (1)
myocardial ischemia	36.64	5	8461525 (1), 2194809 (1), 7832112 (1), 10094179 (1)
beta-thalassemia	34.44	12	17874450 (3), 15545996 (2), 16696909 (2), 16186125 (1)
coronary spasm	30.00	1	8488083 (1)
hypertension pulmonary	28.34	4	1868189 (1), 1921472 (1), 2117136 (1), 1424046 (1)

About this table

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/254 PubMed articles for ERAF gene (see all 254 ):

An abundant erythroid protein that stabilizes free alpha-haemoglobin. (PubMed id 12066189)^{2, 3, 4} Kihm A.J....Weiss M.J. (2002)
A novel erythroid-specific marker of transmissible spongiform encephalopathies. (PubMed id 11231637)^{2, 3, 4} Miele G.... Clinton M. (2001)
Biophysical characterization of the alpha-globin binding protein alpha-hemoglobin stabilizing protein. (PubMed id 12192002)^{1, 3, 4} Gell D.... Mackay J.P. (2002)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)^{3, 4} Zhang Q.H....Chen Z. (2000)
Reduction of AHSP synthesis in hemin-induced K562 cells and EPO-induced CD34(+) cells leads to alpha-globin precipitation, impairment of normal hemoglobin production, and increased cell death. (PubMed id 18179859)^{1, 3} Pinho F.O....Costa F.F. (2008)
Population analysis of the alpha hemoglobin stabilizing protein (AHSP) gene identifies sequence variants that alter expression and function. (PubMed id 17874450)^{1, 3} dos Santos C.O....Weiss M.J. (2008)
GATA-1 and Oct-1 are required for expression of the human alpha-hemoglobin-stabilizing protein gene. (PubMed id 16186125)^{1, 3} Gallagher P.G....Bodine D.M. (2005)
Evaluation of alpha hemoglobin stabilizing protein (AHSP) as a genetic modifier in patients with beta thalassemia. (PubMed id 14715623)^{1, 3} Viprakasit V....Higgs D.R. (2004)
An iron responsive element-like stem-loop regulates alpha-hemoglobin-stabilizing protein mRNA. (PubMed id 18676996)^{1, 3} dos Santos C.O....Weiss M.J. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 51327	HGNC: 18075	AceView: ERAF	Ensembl:ENSG00000169877	euGenes: HUgn51327
ECgene: ERAF	H-InvDB: ERAF

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for ERAF
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for ERAF:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ERAF-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ERAF		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ERAF		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (ERAF)
	Antibodies (ERAF)
	Chimera RNAi (ERAF)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (Ahsp)
	Antibodies (Ahsp)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for ERAF

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for ERAF

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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ERAF Gene at Home site.
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ERAF Gene

protein-coding GIFtS: 53

Aliases &
Descriptions
for ERAF

Summaries
for ERAF

Genomic Location
for ERAF

Proteins
for ERAF

Protein Domains/
Families
for ERAF

Gene Function
for ERAF

Pathways & Interactions
for ERAF

Drugs & Compounds
for ERAF

Transcripts
for ERAF

Expression
for ERAF

Orthologs
for ERAF

Paralogs
for ERAF

SNPs/Variants
for ERAF

Disorders & Mutations
for ERAF

Medical News
for ERAF

Publications
for ERAF

Search for ERAF

Genome Databases showing ERAF

Other Databases showing ERAF

Specialized Databases showing ERAF

Licensable Technologies
for ERAF

Services
for ERAF

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ERAF Gene

protein-coding GIFtS: 53

Aliases & Descriptionsfor ERAF

Summariesfor ERAF

Genomic Locationfor ERAF

Proteinsfor ERAF

Protein Domains/Familiesfor ERAF

Gene Functionfor ERAF

Pathways & Interactionsfor ERAF

Drugs & Compoundsfor ERAF

Transcriptsfor ERAF

Expression for ERAF

Orthologsfor ERAF

Paralogsfor ERAF

SNPs/Variantsfor ERAF

Disorders & Mutationsfor ERAF

Medical Newsfor ERAF

Publicationsfor ERAF

Search for ERAF

Genome Databases showing ERAF

Other Databases showing ERAF

Specialized Databases showing ERAF

Licensable Technologiesfor ERAF

Servicesfor ERAF

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ERAF

Summaries
for ERAF

Genomic Location
for ERAF

Proteins
for ERAF

Protein Domains/
Families
for ERAF

Gene Function
for ERAF

Pathways & Interactions
for ERAF

Drugs & Compounds
for ERAF

Transcripts
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