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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

EPYC Gene

protein-coding   GIFtS: 49
GCID: GC12M091357

epiphycan

(Previous names: dermatan sulphate proteoglycan 3, dermatan sulfate proteoglycan...)
(Previous symbol: DSPG3)
 Explore 3 diseases affiliated with
EPYC via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for EPYC    

Aliases
for EPYC gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Epiphycan1     PGLB2 3
DSPG31 2 3 5     Dermatan Sulphate Proteoglycan 31
Dermatan Sulfate Proteoglycan 31 2 3     Epiphycan Proteoglycan2
SLRR3B1 2 3     Proteoglycan-Lb3
Pg-Lb1 2     PG-Lb3
Small Chondroitin/Dermatan Sulfate Proteoglycan2 3     Proteoglycan-Lb3

External Ids:    HGNC: 30531   Entrez Gene: 18332   Ensembl: ENSG000000837827   OMIM: 6016575   UniProtKB: Q996453   

Export aliases for EPYC gene to outside databases

Previous GC identifers: GC12M089881 GC12M088425


Summaries
for EPYC gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for EPYC:
Dermatan sulfate proteoglycan 3 is a member of the small leucine-rich repeat proteoglycan family. This gene is composed
of seven exons. It regulates fibrillogenesis by interacting with collagen fibrils and other extracellular matrix
proteins. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: EPYC_HUMAN, Q99645
Function: May have a role in bone formation and also in establishing the ordered structure of cartilage through matrix
organization




Genomic Views
for EPYC gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.1  NT_029419.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the EPYC gene promoter:
         Nkx3-1   TBP   Nkx3-1 v4   Nkx3-1 v1   CUTL1   Nkx3-1 v2   SRY   S8   HFH-1   Nkx3-1 v3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: EPYC promoter sequence
   Search SABiosciences Chromatin IP Primers for EPYC

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat EPYC


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q21   Ensembl cytogenetic band:  12q21.33   HGNC cytogenetic band: 12q21

EPYC Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
EPYC gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M091357:  view genomic region     (about GC identifiers)

Start:
 91,357,456 bp from pter      End:
 91,398,803 bp from pter
Size:
 41,348 bases      Orientation:
 minus strand

Proteins
for EPYC gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: EPYC_HUMAN, Q99645 (See protein sequence)
Recommended Name: Epiphycan precursor  
Size: 322 amino acids; 36637 Da
Subcellular location: Secreted, extracellular space, extracellular matrix (By similarity)
Secondary accessions: A8K3M7 Q8NEJ5

Explore the universe of human proteins at neXtProt for EPYC: NX_Q99645

Post-translational modifications:

  • The O-linked polysaccharides on Thr-60 and Ser-96 are probably the mucin type linked to GalNAc. There is one
    • glycosaminoglycan chain, known to be dermatan sulfate, and it is probably the O-glycosylation at Ser-64 (By
    similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q99645

    • EPYC Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_004941.2  
    ENSEMBL proteins: 
     ENSP00000261172   ENSP00000448272  

    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: EPYC
    OriGene Custom Protein Services for EPYC 
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    Novus Biologicals EPYC Protein
    Novus Biologicals EPYC Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for EPYC

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005578proteinaceous extracellular matrix IEA--


    EPYC for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for EPYC

    Protein Domains /
    Families
    for EPYC gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    EPYC for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR001611 Leu-rich_rpt
     IPR000372 LRR-contain_N
     IPR027217 Epiphycan

    Graphical View of Domain Structure for InterPro Entry Q99645

    ProtoNet protein and cluster: Q99645

    1 Blocks protein family: IPB000372 Cysteine-rich flanking region

    UniProtKB/Swiss-Prot: EPYC_HUMAN, Q99645
    Similarity: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily
    Similarity: Contains 6 LRR (leucine-rich) repeats
    Similarity: Contains 1 LRRNT domain


    Function
    for EPYC gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: EPYC_HUMAN, Q99645
    Function: May have a role in bone formation and also in establishing the ordered structure of cartilage through matrix
    organization

    miRNA
    Products:            		 OriGene 3'-UTR Clone: EPYC
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat EPYC
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate EPYC
    SwitchGear 3'UTR luciferase reporter plasmid: EPYC 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for EPYC (see all 7)
    OriGene shRNA RFP: EPYC
    OriGene siRNA: EPYC
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat EPYC

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for EPYC

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for EPYC (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for EPYC (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: EPYC (NM_004950)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat EPYC 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for EPYC
    LifeMap BioReagents: cell lines associated with EPYC: Chondrogenic Package 4D20.8,
    Chondrogenic Package 7SMOO32, Chondrogenic Package E15, Chondrogenic Package SM30

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EPYC

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005539glycosaminoglycan binding TAS8975717


    EPYC for ontologies           About GeneDecksing



    Pathways & Interactions
    for EPYC gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for EPYC

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007565female pregnancy TAS8975717


    EPYC for ontologies           About GeneDecksing



    Drugs & Compounds
    for EPYC gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for EPYC
    Search CenterWatch for drugs/clinical trials and news about EPYC 

    Transcripts
    for EPYC gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for EPYC gene: 
    NM_004950.4  

    Unigene Cluster for EPYC:

    Epiphycan
    Hs.435680  [show with all ESTs]
    Unigene Representative Sequence: BC030958
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000261172(uc001tbk.3) ENST00000551767 ENST00000550203

    miRNA
    Products:             		 OriGene 3'-UTR Clone: EPYC
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat EPYC
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate EPYC
    SwitchGear 3'UTR luciferase reporter plasmid: EPYC 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for EPYC (see all 7)
    OriGene shRNA RFP: EPYC
    OriGene siRNA: EPYC
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat EPYC
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for EPYC (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for EPYC (see first 1)
    NM_004950 (human cat#: SC321109)  NM_004950 (human cat#: SC117046)  
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: EPYC (NM_004950)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for EPYC
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat EPYC 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for EPYC
    Browse OriGene validated miRNA SYBR primer pairs
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat EPYC
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat EPYC

    Additional cDNA sequence: 

    AK290642.1 BC030958.1 U59111.1 

    2 DOTS entries:

    DT.409206  DT.75119242 

    24/43 AceView cDNA sequences (see all 43):

    AU099648 AU118100 AA456742 AU118612 BQ006809 AI276878 BQ015670 BX365045 
    AU117240 AU119962 CR598976 CR612682 BX343971 BQ007792 CA412703 U59111 
    BX343970 AI128100 CB215626 BC030958 BQ002814 BF062835 AI376440 AU116867 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for EPYC    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7
    SP1:                                                
    SP2:                                                


    ECgene alternative splicing isoforms for EPYC

    Expression
    for EPYC gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    EPYC expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AAAAAAAGAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    EPYC expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    10/11 LifeMap In Vivo Development Anatomical Compartments/Cells (see all 11) 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BoneZeugopod Epiphyseal EndChondrocytesBone, Cartilage
    OvaryAntral FollicleCumulus CellsOvary
    BoneEndochondral Facial BonesBone
    BoneStylopod Long BoneBone
    BoneThoracic RibBone
    BoneZeugopod Growth PlateBone
    BoneZeugopod Long BoneBone
    BrainMeningesBrain
    EyeOuter Nuclear LayerEye
    Skeletal MuscleExtraocular MusclesSkeletal Muscle
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 10/12 LifeMap Cells (see all 12) 
    NameCategory
    Articular chondrocyte-like cells (HyStem chondrogenic ...)Cartilage
    Micromass-induced chondrocytes (Micromass chondrogen...)Bone, Cartilage
    HyStem+TGF?3+GDF5-induced SM30 cells (HyStem+TGF?3+GDF5 in...)Bone, Cartilage
    Micromass-induced chondrocytes (Micromass chondrogen...)Bone, Cartilage
    HyStem+TGF?3+GDF5-induced 7PEND24 cells (HyStem+TGF?3+GDF5 in...)Bone
    HyStem+BMP4-induced 4D20.8 cells (Chondrogenic inducti...)Bone, Cartilage
    HyStem+TGF?3+GDF5-induced 4D20.8 cells (HyStem+TGF?3+GDF5 in...)Bone, Cartilage
    Micromass-induced chondrocytes (Micromass chondrogen...)Bone, Cartilage
    Micromass-induced chondrocytes (Micromass chondrogen...)Bone, Cartilage
    HyStem+TGF?3+GDF5-induced E15 cells (HyStem+TGF?3+GDF5 in...)Bone, Cartilage

    See EPYC Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for EPYC

    SOURCE GeneReport for Unigene cluster: Hs.435680

    UniProtKB/Swiss-Prot: EPYC_HUMAN, Q99645
    Tissue specificity: Cartilage, ligament, and placenta

        SABiosciences Custom PCR Arrays for EPYC
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EPYC

    Orthologs
    for EPYC gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for EPYC gene from 4/14 species (see all 14)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves EPYC1 epiphycan 70.16(n)
    68.57(a)    		   417890  NM_001004382.1  NP_001004382.1 
    lizard
    (Anolis carolinensis)    		 Reptilia EPYC6
    		 --
    		 65(a)
    		 1 ↔ 1
    		 5(32389428-32417779)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia BX739544.12   -- 74.89(n)    BX739544.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii BX322608.16
    epyc6
    		 epiphycan
    		 8(a)
    46(a)
    		 possible ortholog
    1 ↔ 1
    		 4(15514306-15518163)
    4(15388347-15402128)


    ENSEMBL Gene Tree for EPYC (if available)
    TreeFam Gene Tree for EPYC (if available) 

    Paralogs
    for EPYC gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for EPYC gene
    OGN2  OPTC2  PODN2  PODNL12  FMOD2  PRELP2  KERA2  ASPN2  
    OMD2  BGN2  DCN2  ECM22  LUM2  
    2 SIMAP similar genes for EPYC using alignment to 2 protein entries:     EPYC_HUMAN (see all proteins):
    OGN    OPTC

    EPYC for paralogs           About GeneDecksing



    Genomic Variants
    for EPYC gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/787 NCBI SNPs in EPYC are shown (see all 787)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 12 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1388570921,2
    		Cother91358079(+) ATCTTC/TGTGCA 2 K E mis11Minor allele frequency- T:0.00NA 4538
    rs666002551,2
    		C--88439816(+) ATCTG-/AAAAAA 1 -- int11Minor allele frequency- A:0.00NA 2
    rs1828403781,2
    		--91357152(+) TTCAGC/TTTTGA 1 -- ds50010--------
    rs1469086011,2
    		--91357200(+) AAAGAC/TGAACT 1 -- ds50010--------
    rs111058861,2
    		C,F,A,H,--91357349(+) TCAGCG/TCTTTA 1 -- ds500124Minor allele frequency- T:0.41NA NS EA WA CSA 2488
    rs784931581,2
    		F,--91357369(+) AAAGTT/CATAAT 1 -- ds50011Minor allele frequency- C:0.18WA 118
    rs1884129091,2
    		--91357590(+) CTAAAC/GTGTTC 1 -- ut310--------
    rs779607541,2
    		--91357599(+) TCATTT/CCAAAA 1 -- ut311Minor allele frequency- C:0.01NA 120
    rs1177597171,2
    		F,--91357658(+) CTAAAA/GCTTGC 1 -- ut311Minor allele frequency- G:0.02NA 120
    rs57999681,2
    		C,--91357786(+) TTTTC-/ATTAT 
                ATTAT     		1 -- ut310--------

    HapMap Linkage Disequilibrium report for EPYC (91357456 - 91398803 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for EPYC: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing EPYC
    DNA2.0 Custom Variant and Variant Library Synthesis for EPYC

    Disorders / Diseases
    for EPYC gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    EPYC for disorders           About GeneDecksing

    OMIM gene information: 601657    OMIM disorders: --

    3 diseases for EPYC:    About MalaCards
    corneal dystrophy    gastroenteritis    myopia

    1 disease from the University of Copenhagen DISEASES database for EPYC:
    Myopia
    Human Genome Epidemiology (HuGE) Navigator: EPYC (3 documents)

    Export disorders for EPYC gene to outside databases

    Publications
    for EPYC gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for EPYC gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with EPYC)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of human DSPG3, a small dermatan sulfate proteoglycan. (PubMed id 8975717)1, 2, 3 Deere M.... Hecht J.T. (1996)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Linkage of posterior amorphous corneal dystrophy to c hromosome 12q21.33 and exclusion of coding region mutations in KERA, LUM, DCN, and EPYC. (PubMed id 20357198)1 Aldave A.J....Gorin M.B. (2010)
    4. An evaluation of OPTC and EPYC as candidate genes for high myopia. (PubMed id 19844586)1 Wang P....Zhang Q. (2009)
    5. The association of haplotype at the lumican gene with high myopia susceptibility in Taiwanese patients. (PubMed id 19616852)1 Chen Z.T....Lin L.L. (2009)
    6. Autosomal dominant cornea plana is not associated with pathogenic mutations in DCN, DSPG3, FOXC1, KERA, LUM, or PITX2. (PubMed id 17558846)1 Aldave A.J....Yellore V.S. (2007)
    7. The association of single nucleotide polymorphisms in the 5'-regulatory region of the lumican gene with susceptibility to high myopia in Taiwan. (PubMed id 16902402)1 Wang I.J....Lin L.L. (2006)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Genomic characterization of human DSPG3. (PubMed id 10330124)1 Deere M....Hecht J.T. (1999)

    External Searches for EPYC gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing EPYC gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1833 HGNC: 3053 AceView: DSPG3 Ensembl:ENSG00000083782 euGenes: HUgn1833
    ECgene: EPYC H-InvDB: EPYC

    Other Databases showing EPYC gene

    (According to HUGE)
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    Specialized Databases showing EPYC gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for EPYC Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for EPYC gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for EPYC gene:
    Search GeneIP for patents involving EPYC

    GeneCards and IP:
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    Products
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     EPYC Proteins, Antibodies, CLIAs, and ELISAs
     Cell Lines associated with EPYC: Chondrogenic Package 4D20.8,
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     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat EPYC
           
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