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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

EPYC Gene

protein-coding   GIFtS: 52
GCID: GC12M091357

Epiphycan

(Previous names: dermatan sulphate proteoglycan 3, dermatan sulfate proteoglycan...)
(Previous symbol: DSPG3)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
epiphycan1 2     SLRR3B2 3
DSPG31 2 3 5     Dermatan Sulphate Proteoglycan 31
Dermatan Sulfate Proteoglycan 31 2 3     Pg-Lb2
Epiphycan Proteoglycan1 2     proteoglycan-lb2
Small Chondroitin/Dermatan Sulfate Proteoglycan2 3     PG-Lb3
PGLB2 3     Proteoglycan-Lb3

External Ids:    HGNC: 30531   Entrez Gene: 18332   Ensembl: ENSG000000837827   OMIM: 6016575   UniProtKB: Q996453   

Export aliases for EPYC gene to outside databases

Previous GC identifers: GC12M089881 GC12M088425


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for EPYC Gene:
Dermatan sulfate proteoglycan 3 is a member of the small leucine-rich repeat proteoglycan family. This gene is
composed of seven exons. It regulates fibrillogenesis by interacting with collagen fibrils and other
extracellular matrix proteins. (provided by RefSeq, Jul 2008)

GeneCards Summary for EPYC Gene: 
EPYC (epiphycan) is a protein-coding gene. Diseases associated with EPYC include posterior amorphous corneal dystrophy, and corneal dystrophy. GO annotations related to this gene include glycosaminoglycan binding. An important paralog of this gene is OGN.

UniProtKB/Swiss-Prot: EPYC_HUMAN, Q99645
Function: May have a role in bone formation and also in establishing the ordered structure of cartilage through
matrix organization




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.2  NT_029419.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the EPYC gene promoter:
         Nkx3-1   TBP   Nkx3-1 v4   Nkx3-1 v1   CUTL1   Nkx3-1 v2   SRY   S8   HFH-1   Nkx3-1 v3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidEPYC promoter sequence
   Search SABiosciences Chromatin IP Primers for EPYC

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat EPYC


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q21   Ensembl cytogenetic band:  12q21.33   HGNC cytogenetic band: 12q21

EPYC Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
EPYC gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M091357:  view genomic region     (about GC identifiers)

Start:
91,357,456 bp from pter      End:
91,398,803 bp from pter
Size:
41,348 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: EPYC_HUMAN, Q99645 (See protein sequence)
Recommended Name: Epiphycan precursor  
Size: 322 amino acids; 36637 Da
Subcellular location: Secreted, extracellular space, extracellular matrix (By similarity)
Secondary accessions: A8K3M7 Q8NEJ5

Explore the universe of human proteins at neXtProt for EPYC: NX_Q99645

Explore proteomics data for EPYC at MOPED 

Post-translational modifications:

  • UniProtKB: The O-linked polysaccharides on Thr-60 and Ser-96 are probably the mucin type linked to GalNAc. There is one
    glycosaminoglycan chain, known to be dermatan sulfate, and it is probably the O-glycosylation at Ser-64 (By
    similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q99645

  • EPYC Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    EPYC Protein Expression
    REFSEQ proteins: NP_004941.2  
    ENSEMBL proteins: 
     ENSP00000261172   ENSP00000448272  

    Human Recombinant Protein Products for EPYC: 
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    OriGene MassSpec for EPYC 
    OriGene Custom Protein Services for EPYC
    GenScript Custom Purified and Recombinant Proteins Services for EPYC
    Novus Biologicals EPYC Protein
    Novus Biologicals EPYC Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for EPYC 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005578proteinaceous extracellular matrix IEA--

    EPYC for ontologies           About GeneDecksing



    EPYC Antibody Products: 
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    Cloud-Clone Corp. CLIAs for EPYC


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SLRR: Proteoglycans / Extracellular Matrix : Small leucine-rich repeats

    3 InterPro protein domains:
     IPR001611 Leu-rich_rpt
     IPR000372 LRR-contain_N
     IPR027217 Epiphycan

    Graphical View of Domain Structure for InterPro Entry Q99645

    ProtoNet protein and cluster: Q99645

    1 Blocks protein domain: IPB000372 Cysteine-rich flanking region

    UniProtKB/Swiss-Prot: EPYC_HUMAN, Q99645
    Similarity: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily
    Similarity: Contains 6 LRR (leucine-rich) repeats
    Similarity: Contains 1 LRRNT domain


    EPYC for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: EPYC_HUMAN, Q99645
    Function: May have a role in bone formation and also in establishing the ordered structure of cartilage through
    matrix organization

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0005539glycosaminoglycan binding TAS8975717
         
    EPYC for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for EPYC 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for EPYC

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for EPYC 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for EPYC 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat EPYC
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate EPYC
    SwitchGear 3'UTR luciferase reporter plasmidEPYC 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
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    Gene Editing
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    OriGene ORF clones in mouse, rat for EPYC
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: EPYC (NM_004950)
    Sino Biological Human cDNA Clone for EPYC
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for EPYC
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat EPYC
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                         Customized lentivirus expression plasmids for stable overexpression of EPYC 

    Cell Line
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    LifeMap BioReagents: cell lines associated with EPYC: Chondrogenic Package 4D20.8,
    Chondrogenic Package 7SMOO32, Chondrogenic Package E15,
    Chondrogenic Package SM30
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EPYC


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for EPYC

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007565female pregnancy TAS8975717

    EPYC for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for EPYC

    Search CenterWatch for drugs/clinical trials and news about EPYC

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for EPYC gene: 
    NM_004950.4  

    Unigene Cluster for EPYC:

    Epiphycan
    Hs.435680  [show with all ESTs]
    Unigene Representative Sequence: BC030958
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000261172(uc001tbk.3) ENST00000551767 ENST00000550203
    miRNA
    Products:
         
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    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for EPYC
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat EPYC
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for EPYC
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                         Customized lentivirus expression plasmids for stable overexpression of EPYC 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for EPYC
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat EPYC
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat EPYC

    Additional mRNA sequence: 

    AK290642.1 BC030958.1 U59111.1 

    2 DOTS entries:

    DT.409206  DT.75119242 

    24/43 AceView cDNA sequences (see all 43):

    CR612682 AU117240 BQ015670 AA456742 BX343971 AI276878 AU118612 AU099648 
    AU119962 BQ006809 AU118100 CR598976 BX365045 BQ011892 NM_004950 BQ574964 
    AA628497 AI376440 BQ007792 AL549460 BQ002814 BQ448017 BF062835 AU116867 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for EPYC    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7
    SP1:                                                
    SP2:                                                


    ECgene alternative splicing isoforms for EPYC

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    EPYC expression in normal human tissues (normalized intensities)      EPYC embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAAAAAAGAA
    EPYC Expression
    About this image


    EPYC expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/14 selected tissues (see all 14) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 25 entries
             Chondrocytes Zeugopod Epiphyseal End
             Zeugopod Long Bone
             HyStem+BMP4-induced 4D20.8 cells
             skeleton/pectoral girdle and thoracic body wall/scapula   
     
     Cartilage (Muscoskeletal System)    fully expand to see all 19 entries
             Mesenchymal Condensate Cells Zeugopod
             HyStem+BMP4-induced 4D20.8 cells
             sensory organ/nose/nasal septum   
     
     Brain (Nervous System)    fully expand to see all 11 entries
             Medulla Oblongata
             Midbrain   
     
     Somite (Muscoskeletal System)    fully expand to see all 4 entries
             skeleton/axial skeleton/sacral region   
     
     Paraxial Mesoderm (Muscoskeletal System)    fully expand to see all 4 entries
             skeleton/axial skeleton/sacral region   

    See EPYC Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for EPYC

    SOURCE GeneReport for Unigene cluster: Hs.435680

    UniProtKB/Swiss-Prot: EPYC_HUMAN, Q99645
    Tissue specificity: Cartilage, ligament, and placenta

        SABiosciences Custom PCR Arrays for EPYC
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EPYC

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for EPYC gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Epyc1 , 5 epiphycan1, 5 83.95(n)1
    82.3(a)1
      10 (50.35 cM)5
    135161  NM_007884.21  NP_031910.11 
     976440685 
    chicken
    (Gallus gallus)
    Aves EPYC1 epiphycan 70.16(n)
    68.57(a)
      417890  NM_001004382.1  NP_001004382.1 
    lizard
    (Anolis carolinensis)
    Reptilia EPYC6
    Uncharacterized protein
    74(a)
    1 ↔ 1
    5(32387315-32418960)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia BX739544.12   -- 74.89(n)    BX739544.1 
    zebrafish
    (Danio rerio)
    Actinopterygii epyc6
    epiphycan
    51(a)
    1 ↔ 1
    4(15388347-15402128)


    ENSEMBL Gene Tree for EPYC (if available)
    TreeFam Gene Tree for EPYC (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for EPYC gene
    OGN2  OPTC2  
    2 SIMAP similar genes for EPYC using alignment to 2 protein entries:     EPYC_HUMAN (see all proteins):
    OGN    OPTC

    EPYC for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/945 SNPs in EPYC are shown (see all 945)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1388570921,2
    Cuntested191358079(+) ATCTTC/TGTGCA 2 K E mis11Minor allele frequency- T:0.00NA 4538
    rs1828403781,2
    --91357152(+) TTCAGC/TTTTGA 1 -- ds50010--------
    rs1469086011,2
    --91357200(+) AAAGAC/TGAACT 1 -- ds50010--------
    rs111058861,2
    C,F,A,H--91357349(+) TCAGCG/TCTTTA 1 -- ds500124Minor allele frequency- T:0.41NA NS EA WA CSA 2488
    rs784931581,2
    C,F--91357369(+) AAAGTT/CATAAT 1 -- ds50011Minor allele frequency- C:0.18WA 118
    rs1884129091,2
    --91357590(+) CTAAAC/GTGTTC 1 -- ut310--------
    rs779607541,2
    C,F--91357599(+) TCATTT/CCAAAA 1 -- ut311Minor allele frequency- C:0.01NA 120
    rs1177597171,2
    C,F--91357658(+) CTAAAA/GCTTGC 1 -- ut311Minor allele frequency- G:0.02NA 120
    rs30470731,2
    C--91357787(+) TTATA-/ATTA  
     T
    /TTATA
    ACATT
    2 -- ut311NA 2
    rs2020194801,2
    --91357907(+) TAGCCA/GTCGTA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for EPYC (91357456 - 91398803 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for EPYC:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv832483CNV Gain17160897
    nsv899425CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing EPYC
    DNA2.0 Custom Variant and Variant Library Synthesis for EPYC

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 601657    OMIM disorders: --

    4 diseases for EPYC:    About MalaCards
    posterior amorphous corneal dystrophy    corneal dystrophy    gastroenteritis    myopia

    1 disease from the University of Copenhagen DISEASES database for EPYC:
    Myopia

    EPYC for disorders           About GeneDecksing

    Genetic Association Database (GAD): EPYC
    Human Genome Epidemiology (HuGE) Navigator: EPYC (3 documents)

    Export disorders for EPYC gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for EPYC gene integrated from 9 sources (see top 10):
    (articles sorted by number of sources associating them with EPYC)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of human DSPG3, a small dermatan sulfate proteoglycan. (PubMed id 8975717)1, 2, 3 Deere M.... Hecht J.T. (1996)
    2. An evaluation of OPTC and EPYC as candidate genes for high myopia. (PubMed id 19844586)1, 4 Wang P....Zhang Q. (2009)
    3. The association of haplotype at the lumican gene with high myopia susceptibility in Taiwanese patients. (PubMed id 19616852)1, 4 Chen Z.T....Lin L.L. (2009)
    4. The association of single nucleotide polymorphisms in the 5'-regulatory region of the lumican gene with susceptibility to high myopia in Taiwan. (PubMed id 16902402)1, 4 Wang I.J....Lin L.L. (2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Linkage of posterior amorphous corneal dystrophy to c hromosome 12q21.33 and exclusion of coding region mutations in KERA, LUM, DCN, and EPYC. (PubMed id 20357198)1 Aldave A.J....Gorin M.B. (2010)
    7. Autosomal dominant cornea plana is not associated with pathogenic mutations in DCN, DSPG3, FOXC1, KERA, LUM, or PITX2. (PubMed id 17558846)1 Aldave A.J....Yellore V.S. (2007)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Genomic characterization of human DSPG3. (PubMed id 10330124)1 Deere M....Hecht J.T. (1999)
    11. Molecular cloning and expression of two small leucine-rich proteoglycan (SLRP) genes, dspg3l and optcl, in zebrafish. (PubMed id 16458084)9 Zhou W....Kuwada J.Y. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1833 HGNC: 3053 AceView: DSPG3 Ensembl:ENSG00000083782 euGenes: HUgn1833
    ECgene: EPYC H-InvDB: EPYC

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for EPYC Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for EPYC gene:
    Search GeneIP for patents involving EPYC

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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