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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

EPYC Gene

protein-coding GIFtS: 52
GCID: GC12M091357

Epiphycan

(Previous names: dermatan sulphate proteoglycan 3, dermatan sulfate proteoglycan...)
(Previous symbol: DSPG3)

4 related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
epiphycan¹ ²		SLRR3B² ³
DSPG3¹ ² ³ ⁵		Dermatan Sulphate Proteoglycan 3¹
Dermatan Sulfate Proteoglycan 3¹ ² ³		Pg-Lb²
Epiphycan Proteoglycan¹ ²		proteoglycan-lb²
Small Chondroitin/Dermatan Sulfate Proteoglycan² ³		PG-Lb³
PGLB² ³		Proteoglycan-Lb³

External Ids:	HGNC: 3053¹	Entrez Gene: 1833²	Ensembl: ENSG00000083782⁷	OMIM: 601657⁵	UniProtKB: Q99645³

Export aliases for EPYC gene to outside databases

Previous GC identifers: GC12M089881 GC12M088425

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for EPYC Gene:

Dermatan sulfate proteoglycan 3 is a member of the small leucine-rich repeat proteoglycan family. This gene is composed

of seven exons. It regulates fibrillogenesis by interacting with collagen fibrils and other extracellular matrix

proteins. (provided by RefSeq, Jul 2008)

GeneCards Summary for EPYC Gene:

EPYC (epiphycan) is a protein-coding gene. Diseases associated with EPYC include posterior amorphous corneal dystrophy, and corneal dystrophy. GO annotations related to this gene include glycosaminoglycan binding. An important paralog of this gene is OGN.

UniProtKB/Swiss-Prot: EPYC_HUMAN, Q99645

Function: May have a role in bone formation and also in establishing the ordered structure of cartilage through matrix

organization

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000012.11 NC_018923.2 NT_029419.12

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the EPYC gene promoter:
Nkx3-1 TBP Nkx3-1 v4 Nkx3-1 v1 CUTL1 Nkx3-1 v2 SRY S8 HFH-1 Nkx3-1 v3
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: EPYC promoter sequence

Search SABiosciences Chromatin IP Primers for EPYC

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat EPYC

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q21 Ensembl cytogenetic band: 12q21.33 HGNC cytogenetic band: 12q21

EPYC Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
EPYC gene location

GeneLoc information about chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12M091357: view genomic region (about GC identifiers)

Start:	91,357,456 bp from pter	End:	91,398,803 bp from pter
Size:	41,348 bases	Orientation:	minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: EPYC_HUMAN, Q99645 (See protein sequence)

Recommended Name: Epiphycan precursor

Size: 322 amino acids; 36637 Da

Subcellular location: Secreted, extracellular space, extracellular matrix (By similarity)

Secondary accessions: A8K3M7 Q8NEJ5

Explore the universe of human proteins at neXtProt for EPYC: NX_Q99645

Explore proteomics data for EPYC at MOPED

Post-translational modifications:

UniProtKB: The O-linked polysaccharides on Thr-60 and Ser-96 are probably the mucin type linked to GalNAc. There is one

glycosaminoglycan chain, known to be dermatan sulfate, and it is probably the O-glycosylation at Ser-64 (By

similarity)

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q99645

EPYC Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins: NP_004941.2

ENSEMBL proteins:

ENSP00000261172 ENSP00000448272

Human Recombinant Protein Products for EPYC:

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	Novus Biologicals EPYC Protein Novus Biologicals EPYC Lysate
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	Browse ProSpec Recombinant Proteins
	Cloud-Clone Corp. Proteins for EPYC

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005578	proteinaceous extracellular matrix	IEA	--

EPYC for ontologies About GeneDecksing

EPYC Antibody Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HGNC Gene Families:

SLRR: Proteoglycans / Extracellular Matrix : Small leucine-rich repeats

3 InterPro protein domains:

IPR001611 Leu-rich_rpt

IPR000372 LRR-contain_N

IPR027217 Epiphycan

Graphical View of Domain Structure for InterPro Entry Q99645

ProtoNet protein and cluster: Q99645

1 Blocks protein domain: IPB000372 Cysteine-rich flanking region

UniProtKB/Swiss-Prot: EPYC_HUMAN, Q99645

Similarity: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily

Similarity: Contains 6 LRR (leucine-rich) repeats

Similarity: Contains 1 LRRNT domain

EPYC for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: EPYC_HUMAN, Q99645

Function: May have a role in bone formation and also in establishing the ordered structure of cartilage through matrix

organization

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	--	--
GO:0005539	glycosaminoglycan binding	TAS	8975717

EPYC for ontologies About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Custom generated mouse model solutions for EPYC

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for EPYC

miRNA Products:
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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for EPYC
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EPYC

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for EPYC

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007565	female pregnancy	TAS	8975717

EPYC for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, IUPHAR, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for EPYC

Search CenterWatch for drugs/clinical trials and news about EPYC

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for EPYC gene:

NM_004950.4

Unigene Cluster for EPYC:

Epiphycan

Hs.435680 [show with all ESTs]

Unigene Representative Sequence: BC030958

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000261172(uc001tbk.3) ENST00000551767 ENST00000550203

miRNA Products:
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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for EPYC
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		Sirion Biotech Custom design and validation of potent shRNA sequences against EPYC

Clone Products:		OriGene clones in human, mouse for EPYC (see all 8) OriGene ORF clones in mouse, rat for EPYC OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: EPYC (NM_004950)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for EPYC
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat EPYC

Primer Products:		OriGene qPCR primer pairs and template standards for EPYC OriGene qSTAR qPCR primer pairs in human, mouse for EPYC
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat EPYC
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat EPYC
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat EPYC

Additional mRNA sequence:

AK290642.1 BC030958.1 U59111.1

2 DOTS entries:

DT.409206 DT.75119242

24/43 AceView cDNA sequences (see all 43):

CR612682 AU117240 BQ015670 AA456742 BX343971 AI276878 AU118612 AU099648

AU119962 BQ006809 AU118100 CR598976 BX365045 BQ011892 NM_004950 BQ574964

AA628497 AI376440 BQ007792 AL549460 BQ002814 BQ448017 BF062835 AU116867

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for EPYC About this scheme

ExUns:	1	^	2	^	3a	·	3b	^	4	^	5	^	6	^	7
SP1:
SP2:

ECgene alternative splicing isoforms for EPYC

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

EPYC expression in normal human tissues (normalized intensities) EPYC embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: AAAAAAAGAA

About this image

EPYC expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database

5/15 selected tissues (see all 15) fully expand


Bone (Muscoskeletal System) fully expand to see all 28 entries
Chondrocytes Zeugopod Epiphyseal End
Zeugopod Long Bone
HyStem+BMP4-induced 4D20.8 cells
skeleton/pectoral girdle and thoracic body wall/scapula

Cartilage (Muscoskeletal System) fully expand to see all 23 entries
Mesenchymal Condensate Cells Zeugopod
HyStem+BMP4-induced 4D20.8 cells
sensory organ/nose/nasal septum

Brain (Nervous System) fully expand to see all 13 entries
Medulla Oblongata
Midbrain

Somite (Muscoskeletal System) fully expand to see all 4 entries
skeleton/axial skeleton/sacral region

Paraxial Mesoderm (Gastrulation Derivatives) fully expand to see all 4 entries
skeleton/axial skeleton/sacral region

See EPYC Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for EPYC

SOURCE GeneReport for Unigene cluster: Hs.435680

UniProtKB/Swiss-Prot: EPYC_HUMAN, Q99645

Tissue specificity: Cartilage, ligament, and placenta

SABiosciences Custom PCR Arrays for EPYC

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat EPYC

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EPYC

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for EPYC gene from 5/12 species (see all 12) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Epyc^{1 , 5}	epiphycan^{1, 5}	83.95(n)¹ 82.3(a)¹		10 (50.35 cM)⁵ 13516¹ NM_007884.2¹ NP_031910.1¹ 97644068⁵
chicken (Gallus gallus)	Aves	EPYC¹	epiphycan	70.16(n) 68.57(a)		417890 NM_001004382.1 NP_001004382.1
lizard (Anolis carolinensis)	Reptilia	EPYC⁶	Uncharacterized protein	74(a)	1 ↔ 1	5(32387315-32418960)
tropical clawed frog (Xenopus tropicalis)	Amphibia	BX739544.1²	--	74.89(n)		BX739544.1
zebrafish (Danio rerio)	Actinopterygii	epyc⁶	epiphycan	51(a)	1 ↔ 1	4(15388347-15402128)

ENSEMBL Gene Tree for EPYC (if available)
TreeFam Gene Tree for EPYC (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for EPYC gene

OGN² OPTC²

2 SIMAP similar genes for EPYC using alignment to 2 protein entries: EPYC_HUMAN (see all proteins):

OGN OPTC

EPYC for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 12 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs138857092^1,2	C	untested¹	91358079(+)	`ATCTTC/TGTGCA`	2	K E	mis¹		1		NA	4538
rs182840378^1,2		--	91357152(+)	`TTCAGC/TTTTGA`	1	--	ds500¹		0	--	--	--	--
rs146908601^1,2		--	91357200(+)	`AAAGAC/TGAACT`	1	--	ds500¹		0	--	--	--	--
rs11105886^1,2	C,F,A,H	--	91357349(+)	`TCAGCG/TCTTTA`	1	--	ds500¹		24		NA NS EA WA CSA	2488
rs78493158^1,2	C,F	--	91357369(+)	`AAAGTT/CATAAT`	1	--	ds500¹		1		WA	118
rs188412909^1,2		--	91357590(+)	`CTAAAC/GTGTTC`	1	--	ut3¹		0	--	--	--	--
rs77960754^1,2	C,F	--	91357599(+)	`TCATTT/CCAAAA`	1	--	ut3¹		1		NA	120
rs117759717^1,2	C,F	--	91357658(+)	`CTAAAA/GCTTGC`	1	--	ut3¹		1		NA	120
rs3047073^1,2	C	--	91357787(+)	`TTATA-/ATTA T/TTATAACATT`	2	--	ut3¹		1		NA	2
rs202019480^1,2		--	91357907(+)	`TAGCCA/GTCGTA`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for EPYC (91357456 - 91398803 bp)

Structural Variations
Database of Genomic Variants (DGV) 2 variations for EPYC: About this table

Variant ID	Type	Subtype	PubMed ID
nsv832483	CNV	Gain	17160897
nsv899425	CNV	Gain	21882294

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing EPYC

DNA2.0 Custom Variant and Variant Library Synthesis for EPYC

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

EPYC for disorders           About GeneDecksing

OMIM gene information: 601657    OMIM disorders: --

4 diseases for EPYC:    About MalaCards

posterior amorphous corneal dystrophy corneal dystrophy gastroenteritis myopia

1 disease from the University of Copenhagen DISEASES database for EPYC:

Myopia

Genetic Association Database (GAD): EPYC
Human Genome Epidemiology (HuGE) Navigator: EPYC (3 documents)

Export disorders for EPYC gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for EPYC gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with EPYC)

Utopia: connect your pdf to the dynamic
world of online information

Characterization of human DSPG3, a small dermatan sulfate proteoglycan. (PubMed id 8975717)^{1, 2, 3} Deere M.... Hecht J.T. (1996)
An evaluation of OPTC and EPYC as candidate genes for high myopia. (PubMed id 19844586)^{1, 4} Wang P....Zhang Q. (2009)
The association of haplotype at the lumican gene with high myopia susceptibility in Taiwanese patients. (PubMed id 19616852)^{1, 4} Chen Z.T....Lin L.L. (2009)
The association of single nucleotide polymorphisms in the 5'-regulatory region of the lumican gene with susceptibility to high myopia in Taiwan. (PubMed id 16902402)^{1, 4} Wang I.J....Lin L.L. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Linkage of posterior amorphous corneal dystrophy to c hromosome 12q21.33 and exclusion of coding region mutations in KERA, LUM, DCN, and EPYC. (PubMed id 20357198)¹ Aldave A.J....Gorin M.B. (2010)
Autosomal dominant cornea plana is not associated with pathogenic mutations in DCN, DSPG3, FOXC1, KERA, LUM, or PITX2. (PubMed id 17558846)¹ Aldave A.J....Yellore V.S. (2007)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)² Ota T.... Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Genomic characterization of human DSPG3. (PubMed id 10330124)¹ Deere M....Hecht J.T. (1999)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 1833	HGNC: 3053	AceView: DSPG3	Ensembl:ENSG00000083782	euGenes: HUgn1833
ECgene: EPYC	H-InvDB: EPYC

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for EPYC	Pharmacogenomics, SNPs, Pathways

Intellectual Property for EPYC gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for EPYC gene:
Search GeneIP for patents involving EPYC

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section


	EMD Millipore Custom Antibody & Bulk Services
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	Regulatory tfbs in EPYC promoter
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Search Tocris compounds for EPYC

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	Proteins for EPYC
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Cell Lines associated with EPYC: Chondrogenic Package 4D20.8,
Chondrogenic Package 7SMOO32, Chondrogenic Package E15,
Chondrogenic Package SM30

	Gene Synthesis
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EPYC

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Search ThermoFisher Antibodies for EPYC

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat EPYC

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LSBio Antibodies in human, mouse, rat for EPYC

GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013

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EPYC Gene

Epiphycan

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Specialized Databases showing EPYC gene

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Summaries
for EPYC gene

Genomic Views
for EPYC gene

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for EPYC gene

Protein Domains /
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for EPYC gene

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for EPYC gene

Pathways & Interactions
for EPYC gene

Drugs & Compounds
for EPYC gene

Transcripts
for EPYC gene

Expression
for EPYC gene

Orthologs
for EPYC gene

Paralogs
for EPYC gene

Genomic Variants
for EPYC gene

Disorders / Diseases
for EPYC gene

Publications
for EPYC gene

Intellectual Property
for EPYC gene

Products
for EPYC gene