Aliases for EPPK1 Gene
External Ids for EPPK1 Gene
Previous GeneCards Identifiers for EPPK1 Gene
The protein encoded by this gene belongs to the plakin family of proteins, which play a role in the organization of cytoskeletal architecture. This family member is composed of several highly homologous plakin repeats. It may function to maintain the integrity of keratin intermediate filament networks in epithelial cells. Studies of the orthologous mouse protein suggest that it accelerates keratinocyte migration during wound healing. [provided by RefSeq, Oct 2013]
GeneCards Summary for EPPK1 Gene
EPPK1 (Epiplakin 1) is a Protein Coding gene. Diseases associated with EPPK1 include melanotic medulloblastoma and vacterl association. Among its related pathways are EGFR1 Signaling Pathway and Cytoskeleton remodeling Neurofilaments. GO annotations related to this gene include poly(A) RNA binding. An important paralog of this gene is DST.