External Ids for EPO Gene
This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. [provided by RefSeq, Jul 2008]
GeneCards Summary for EPO Gene
EPO (Erythropoietin) is a Protein Coding gene. Diseases associated with EPO include acquired pure red cell aplasia and microvascular complications of diabetes 2. Among its related pathways are PI3K-Akt signaling pathway and TGF-Beta Pathway. GO annotations related to this gene include hormone activity and erythropoietin receptor binding.
UniProtKB/Swiss-Prot for EPO Gene
Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass