Aliases for EPN1 Gene
External Ids for EPN1 Gene
Previous GeneCards Identifiers for EPN1 Gene
The protein encoded by this gene binds clathrin and is involved in the endocytosis of clathrin-coated vesicles. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
GeneCards Summary for EPN1 Gene
EPN1 (Epsin 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Interleukin receptor SHC signaling. GO annotations related to this gene include transcription factor binding and phospholipid binding. An important paralog of this gene is EPN3.
UniProtKB/Swiss-Prot for EPN1 Gene
Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations (By similarity). Regulates receptor-mediated endocytosis.