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EPHA10 Gene

protein-coding   GIFtS: 52
GCID: GC01M038181

EPH Receptor A10

  See EPHA10-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
EPH Receptor A101 2
EC 2.7.10.13 8
EphA10s Protein2
Ephrin Type-A Receptor 102

External Ids:    HGNC: 199871   Entrez Gene: 2846562   Ensembl: ENSG000001833177   OMIM: 6111235   UniProtKB: Q5JZY33   

Export aliases for EPHA10 gene to outside databases

Previous GC identifers: GC01M037895 GC01M037952 GC01M036298


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for EPHA10 Gene:
Ephrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are
important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and
epithelial cells (Aasheim et al., 2005 (PubMed 15777695)). See MIM 179610 for additional background on Eph
receptors and ephrins.(supplied by OMIM, Mar 2008)

GeneCards Summary for EPHA10 Gene:
EPHA10 (EPH receptor A10) is a protein-coding gene. Diseases associated with EPHA10 include duodenum cancer. GO annotations related to this gene include transmembrane-ephrin receptor activity and ephrin receptor activity. An important paralog of this gene is EPHB1.

UniProtKB/Swiss-Prot: EPHAA_HUMAN, Q5JZY3
Function: Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_032977.10  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the EPHA10 gene promoter:
         p53   HFH-1   NRSF form 1   AP-2beta   AP-2gamma   AP-2alpha   NRSF form 2   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidEPHA10 promoter sequence
   Search Chromatin IP Primers for EPHA10

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat EPHA10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34.3   Ensembl cytogenetic band:  1p34.3   HGNC cytogenetic band: 1p34.3

EPHA10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
EPHA10 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M038181:  view genomic region     (about GC identifiers)

Start:
38,179,552 bp from pter      End:
38,230,824 bp from pter
Size:
51,273 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: EPHAA_HUMAN, Q5JZY3 (See protein sequence)
Recommended Name: Ephrin type-A receptor 10 precursor  
Size: 1008 amino acids; 109716 Da
Sequence caution: Sequence=AAI12934.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: A4FU89 J3KPB5 Q6NW42
Alternative splicing: 3 isoforms:  Q5JZY3-1   Q5JZY3-2   Q5JZY3-3   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for EPHA10: NX_Q5JZY3

Explore proteomics data for EPHA10 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn311, Asn486
  • Selected DME Specific Peptides for EPHA10 (Q5JZY3) (see all 12)
     GERPYWD  DTIAADE  ALVSVRV  TYQVCNV 


    See EPHA10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001092909.1  NP_775912.2  

    ENSEMBL proteins: 
     ENSP00000436425   ENSP00000431389   ENSP00000432693   ENSP00000362139   ENSP00000436288  
     ENSP00000316395   ENSP00000330379   ENSP00000397746   ENSP00000441822  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    FN3: Fibronectin type III domain containing
    EPH: EPH receptors
    SAMD: Sterile alpha motif (SAM) domain containing

    IUPHAR Guide to PHARMACOLOGY protein family classification: EPH receptor A10
    Ephrin receptor family
    Ephrin receptor family

    Selected InterPro protein domains (see all 14):
     IPR003961 Fibronectin_type3
     IPR021129 SAM_type1
     IPR011009 Kinase-like_dom
     IPR013783 Ig-like_fold
     IPR000719 Prot_kinase_dom

    Graphical View of Domain Structure for InterPro Entry Q5JZY3

    ProtoNet protein and cluster: Q5JZY3

    4 Blocks protein domains:
    IPB001090 Ephrin receptor
    IPB001426 Receptor tyrosine kinase
    IPB001660 Sterile alpha motif SAM
    IPB008266 Tyrosine protein kinase


    UniProtKB/Swiss-Prot: EPHAA_HUMAN, Q5JZY3
    Domain: The protein kinase domain is predicted to be catalytically inactive
    Similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily
    Similarity: Contains 1 Eph LBD (Eph ligand-binding) domain
    Similarity: Contains 2 fibronectin type-III domains
    Similarity: Contains 1 protein kinase domain
    Similarity: Contains 1 SAM (sterile alpha motif) domain


    Find genes that share domains with EPHA10           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: EPHAA_HUMAN, Q5JZY3
    Function: Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5
    Catalytic activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate

         Enzyme Number (IUBMB): EC 2.7.10.11 2

         Gene Ontology (GO): Selected molecular function terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004672protein kinase activity ----
    GO:0004713protein tyrosine kinase activity ----
    GO:0005003ephrin receptor activity IEA--
    GO:0005005transmembrane-ephrin receptor activity IDA15777695
    GO:0005515protein binding IPI15777695
         
    Find genes that share ontologies with EPHA10           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for EPHA10:
     Decreased substrate adherent c 

    Animal Models:
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    Selected qRT-PCR Assays for microRNAs that regulate EPHA10 (see all 37):
    hsa-miR-194* hsa-miR-3194-5p hsa-miR-29a hsa-miR-301a hsa-miR-764 hsa-miR-4314 hsa-miR-124 hsa-miR-3649
    SwitchGear 3'UTR luciferase reporter plasmidEPHA10 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat EPHA10

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    EPHAA_HUMAN, Q5JZY3: Isoform 1: Cell membrane; Single-pass type I membrane protein (Probable)
    EPHAA_HUMAN, Q5JZY3: Isoform 3: Cell membrane; Single-pass type I membrane protein (Probable)
    EPHAA_HUMAN, Q5JZY3: Isoform 2: Secreted (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    extracellular4
    cytosol1
    endoplasmic reticulum1
    lysosome1
    mitochondrion1
    nucleus1
    peroxisome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005887integral component of plasma membrane IEA--
    GO:0016021integral component of membrane NAS15777695

    Find genes that share ontologies with EPHA10           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for EPHA10
    Interactions:

        Search GeneGlobe Interaction Network for EPHA10

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for EPHA10 (ENSP000003163954) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    --ensp: ENSP000003621394STRING: ensp: ENSP00000362139
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation ----
    GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway ----
    GO:0008150biological_process ND--
    GO:0048013ephrin receptor signaling pathway IDA15777695

    Find genes that share ontologies with EPHA10           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for EPHA10 (EPHAA)

    2 HMDB Compounds for EPHA10    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for EPHA10 gene (3 alternative transcripts): 
    NM_001004338.2  NM_001099439.1  NM_173641.2  

    Unigene Cluster for EPHA10:

    EPH receptor A10
    Hs.129435  [show with all ESTs]
    Unigene Representative Sequence: NM_001099439
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000432874(uc001cbt.3) ENST00000534097(uc009vvh.2) ENST00000437645
    ENST00000444950 ENST00000446149 ENST00000373048(uc009vvi.3) ENST00000453577
    ENST00000525749 ENST00000319637(uc001cbw.4) ENST00000330210(uc001cbv.2)
    ENST00000427468(uc001cbu.3) ENST00000540011
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate EPHA10 (see all 37):
    hsa-miR-194* hsa-miR-3194-5p hsa-miR-29a hsa-miR-301a hsa-miR-764 hsa-miR-4314 hsa-miR-124 hsa-miR-3649
    SwitchGear 3'UTR luciferase reporter plasmidEPHA10 3' UTR sequence
    Inhib. RNA
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      QuantiFast Probe-based Assays in human, mouse, rat EPHA10

    Additional mRNA sequence: 

    AJ781169.1 AK090974.1 AK131215.1 AK309089.1 AY726560.1 BC039363.1 BC041360.1 BC067734.1 
    BC112933.1 

    8 DOTS entries:

    DT.308515  DT.99997449  DT.95257798  DT.101973706  DT.121412103  DT.75117652  DT.121393485  DT.99995546 

    6 AceView cDNA sequences:

    AJ781169 BF966478 AK090974 NM_173641 BC067734 AX746712 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for EPHA10    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16
    SP1:                                                              -     -                                       
    SP2:                          -                                         -                                       
    SP3:                                                                                                            


    ECgene alternative splicing isoforms for EPHA10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    EPHA10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    EPHA10 Expression
    About this image

    EPHA10 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    EPHA10 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.129435

    UniProtKB/Swiss-Prot: EPHAA_HUMAN, Q5JZY3
    Tissue specificity: Mainly expressed in testis

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for EPHA10 gene from Selected species (see all 5)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Epha101 , 5 Eph receptor A101, 5 87.85(n)1
    92.75(a)1
      4 (57.92 cM)5
    2307351  NM_001256432.11  NP_001243361.11 
     1248808995 
    chicken
    (Gallus gallus)
    Aves EPHA101 EPH receptor A10 68.84(n)
    63.29(a)
      428219  XM_425778.4  XP_425778.2 
    zebrafish
    (Danio rerio)
    Actinopterygii epha4b6
    eph receptor A4b
    45(a)
    many ↔ many
    2(40081899-40266727) ENSDARG00000011600


    ENSEMBL Gene Tree for EPHA10 (if available)
    TreeFam Gene Tree for EPHA10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for EPHA10 gene
    EPHB12  EPHA22  EPHB32  EPHA42  EPHA52  EPHB62  EPHA62  EPHA12  
    EPHB22  EPHA82  EPHA32  EPHA72  EPHB42  
    Selected SIMAP similar genes for EPHA10 using alignment to 9 protein entries:     EPHAA_HUMAN (see all proteins) (see all similar genes):
    EPHA7    EPHA3    EPHA4    EPHB1    EPHA5    EPHA2
    EPHB2 variant protein    EPHA6    EPHA8    EPHB3    EPHB2    MAP3K10
    FES    TXK    SRC    EPHB4    tec    ABL1

    Find genes that share paralogs with EPHA10           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for EPHA10 (see all 1255)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0421634
    A breast infiltrating ductal carcinoma sample4--see VAR_0421632 H R mis40--------
    VAR_0421594
    A gastric adenocarcinoma sample4--see VAR_0421592 R H mis40--------
    rs6722071,2
    C,F,A--38181153(+) tctcaC/Tcctgg 1 -- int112Minor allele frequency- T:0.42NA WA CSA EA 374
    rs1872972031,2
    --38181173(+) CCATCC/TGAATG 1 -- int10--------
    rs1908870961,2
    --38181222(+) GCTCCA/GAGGTT 1 -- int10--------
    rs1828465951,2
    --38181265(+) TCTGCC/TGCACA 1 -- int10--------
    rs1458389661,2
    --38181323(+) TTTCCC/TGGTCT 1 -- int10--------
    rs75122421,2
    C,F,A,H--38181503(+) TTTCAC/TGGCAG 1 -- int120Minor allele frequency- T:0.23NS EA NA WA EU 2909
    rs614021721,2
    C,F--38181506(+) CACGGC/GAGGAG 1 -- int12Minor allele frequency- G:0.14WA 120
    rs800090121,2
    C--38181549(+) TCAGAC/TGCAGA 1 -- int12Minor allele frequency- T:0.02WA EU 689

    HapMap Linkage Disequilibrium report for EPHA10 (38179552 - 38230824 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for EPHA10 (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2747241CNV Deletion23290073
    esv2671162CNV Deletion23128226
    esv2660836CNV Deletion23128226
    esv2747264CNV Deletion23290073
    esv1005346CNV Deletion20482838
    esv2747253CNV Deletion23290073
    esv2276987CNV Deletion18987734
    esv2747230CNV Deletion23290073
    nsv519553CNV Loss19592680
    nsv525226CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611123    OMIM disorders: --

    1 disease for EPHA10:    
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    duodenum cancer

    1 disease from the University of Copenhagen DISEASES database for EPHA10:
    Duodenum cancer

    Find genes that share disorders with EPHA10           About GenesLikeMe

    Genetic Association Database (GAD): EPHA10

    Export disorders for EPHA10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for EPHA10 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with EPHA10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of a novel Eph receptor tyrosine kinase, EphA10, expressed in testis. (PubMed id 15777695)1, 2, 9 Aasheim H.-C.... Finne E.F. (Biochim. Biophys. Acta 2005)
    2. A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants. (PubMed id 22219177)1, 4 Tao S....Sun J. (Carcinogenesis 2012)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    5. Expression profile of Eph receptors and ephrin ligands in healthy human B lymphocytes and chronic lymphocytic leukemia B-cells. (PubMed id 18819711)1, 9 Alonso-C L.M....Zapata A.G. (Leuk. Res. 2009)
    6. Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. (PubMed id 24144296)1 Cheng C.Y....Baird P.N. (Am. J. Hum. Genet. 2013)
    7. A paradigm shift in EPH receptor interaction: biological relevance of EPHB6 interaction with EPHA2 and EPHB2 in breast carcinoma cell lines. (PubMed id 21737611)1 Fox B.P. and Kandpal R.P. (amp 2011)
    8. Patterns of somatic mutation in human cancer genomes. (PubMed id 17344846)2 Greenman C.... Stratton M.R. (Nature 2007)
    9. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (Nature 2006)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 284656 HGNC: 19987 AceView: FLJ33655 Ensembl:ENSG00000183317 euGenes: HUgn284656
    ECgene: EPHA10 H-InvDB: EPHA10

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for EPHA10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for EPHA10 gene:
    Search GeneIP for patents involving EPHA10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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