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EPHA1 Gene

protein-coding GIFtS: 63

GC07M142798

EPH receptor A1
(Previous name: EphA1 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbols: EPHT, EPHT1)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
EC 2.7.10.1 ^³
EPH ^¹, ², ³
EPHT ^², ³
EPHT1 ^², ³, ⁵
EphA1 ^¹
MGC163163 ^²

Descriptions
EPH receptor A1 ^²
Tyrosine-protein kinase receptor EPH ^², ³
eph tyrosine kinase 1 ^²
ephrin receptor EphA1 ^²
ephrin type-A receptor 1 ^²
erythropoietin-producing hepatoma amplified sequence ^²
oncogene EPH ^²
soluble EPHA1 variant 1 ^²
soluble EPHA1 variant 2 ^²

External Ids
HGNC: 3385¹
Entrez Gene: 2041²
UniProtKB: P21709³
Ensembl: ENSG00000146904⁷

Search outside databases for aliases for EPHA1 gene

Previous GC identifers: GC07M141414 GC07M142482 GC07M142559 GC07M142605

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for EPHA1:

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and

EPH-related receptors have been implicated in mediating developmental events, particularly in the

nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an

extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin

receptors are divided into 2 groups based on the similarity of their extracellular domain

sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed

in some human cancer cell lines and has been implicated in carcinogenesis. [provided by RefSeq]

UniProtKB/Swiss-Prot: EPHA1_HUMAN, P21709

Function: Receptor for members of the ephrin-A family. Binds with a low affinity to ephrin-A1

Gene Wiki entry for EPHA1 (EPH_receptor_A1)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the EPHA1 gene

Entrez Gene cytogenetic band: 7q34 Ensembl cytogenetic band: 7q35 HGNC cytogenetic band: 7q32-q36

EPHA1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07M142798: (about GC identifiers)

Start:	142,798,327 bp from pter
End:	142,816,107 bp from pter
Size:	17,781 bases
Orientation:	minus strand

1 alternative location:

Chr7-,CRA_TCAG 142,490,337-142,508,118

RefSeq DNA sequence:

NC_000007.12 NT_007914.14 NT_079596.2

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: EPHA1_HUMAN, P21709 (See protein sequence)

Recommended Name: Ephrin type-A receptor 1 precursor

Size: 976 amino acids; 108067 Da

Subcellular location: Membrane; Single-pass type I membrane protein

PDB structure from and Proteopedia :

2K1K (3D)

2K1L (3D)

Secondary accessions: Q15405

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_005223.4

ENSEMBL proteins:

ENSP00000275815

Human Recombinant Proteins

	Invitrogen human recombinant proteins for EPHA1
	Millipore Purified and/or Recombinant EPHA1 Protein
	Sigma-Aldrich Proteins for EPHA1
	R&D Systems Recombinant & Natural Proteins for EPHA1
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Eph receptor A1)
	Human Recombinant Proteins from Abnova (EPHA1)

OriGene Purified Recombinant Human Protein: EPHA1

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005887	integral to plasma membrane	TAS	2825356
GO:0016020	membrane	IEA	--

About this table

Antibodies for EPHA1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for EPHA1
	R&D Systems Antibodies for EPHA1
	Cell Signaling Technology (CST) Antibodies for EPHA1
	Antibodies from Abcam (Eph receptor A1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (EPHA1)
	Novus Biologicals Antibodies for EPHA1

Assays for EPHA1:

	Invitrogen Assays for EPHA1
	Browse Kits and Assays available from Millipore
	R&D Systems ELISAs for EPHA1 (see all)
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P21709

ProtoNet protein and cluster: P21709

2 Blocks protein families:

IPB001660 Sterile alpha motif SAM

IPB008266 Tyrosine protein kinase

UniProtKB/Swiss-Prot: EPHA1_HUMAN, P21709

Similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor

subfamily

Similarity: Contains 2 fibronectin type-III domains

Similarity: Contains 1 protein kinase domain

Similarity: Contains 1 SAM (sterile alpha motif) domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (EPHA1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (EPHA1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005232

Applied Biosystems Silencer® siRNAs for EPHA1

Sigma-Aldrich siRNA and siRNA Panels for EPHA1

Sigma-Aldrich shRNA Panels and shRNA for EPHA1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_005232
Myc/DDK tagged cDNA clone in CMV expression vector: NM_005232
untagged cDNA clones in CMV expression vector (see all 2): NM_005232

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_005232

UniProtKB/Swiss-Prot: EPHA1_HUMAN, P21709

Function: Receptor for members of the ephrin-A family. Binds with a low affinity to ephrin-A1

Catalytic activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate

Enzyme Number (IUBMB): EC 2.7.10.1

Genatlas biochemistry entry for EPHA1:

EPH-related tyrosine kinase receptor 1,binding ephrin A1,expressed in projecting neurons and their

target fields,involved in short-range contact-mediated axonal guidance

6 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Epha1):

growth/size	homeostasis/metabolism	immune system	limbs/digits/tail	reproductive system
skeleton

5 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0004872	receptor activity	IEA	--
GO:0005003	ephrin receptor activity	IEA	--
GO:0005524	ATP binding	IEA	--
GO:0016740	transferase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

2 Sigma-Aldrich "Your Favorite Gene" Pathways for EPHA1 (Your Favorite Gene powered by Ingenuity)

Axonal Guidance Signaling
Ephrin Receptor Signaling

GeneDecks EPHA1 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for EPHA1

5/36 Interacting proteins for EPHA1 (ENSP00000275815³) via UniProtKB, MINT, and/or STRING (see all 36 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
EFNA1	ENSP00000357392³	STRING (score=.999)
EFNA2	ENSP00000215368³	STRING (score=.995)
EFNA3	ENSP00000357393³	STRING (score=.995)
EFNA4	ENSP00000357394³	STRING (score=.995)
EFNA5	ENSP00000328777³	STRING (score=.995)

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006468	protein amino acid phosphorylation	IEA	--
GO:0007165	signal transduction	TAS	2825356
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for EPHA1
4 Novoseek chemical compound relationships for EPHA1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
tyrosine	82.98	183	16680165 (2), 8589679 (2), 9053851 (2), 7515363 (2) (see all 99)
nitric oxide	4.22	1	14499344 (1)
pd 98,059	0.14	1	12235151 (1)
fibrinogen	0.00	1	14576067 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (EPHA1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (EPHA1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005232

Sigma-Aldrich siRNA and siRNA Panels for EPHA1

Sigma-Aldrich shRNA Panels and shRNA for EPHA1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_005232

REFSEQ mRNAs for EPHA1 gene:

NM_005232.4

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_005232

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_005232
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_005232
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_005232

Additional cDNA sequence:

AK290351.1 AK313263.1 BC130291.1 BC144156.1 EU826604.1 EU826605.1 M18391.1 Z27409.1

7 DOTS entries:

DT.91721993 DT.100045554 DT.100664350 DT.121640668 DT.100729784 DT.91827212 DT.91721988

24/74 AceView cDNA sequences (see all 74 ):

BM741169 BM741187 W31887 BM710193 BM756676 AI565251 BX090074 BM756648

AW630929 BM671614 AI003571 BI489574 NM_005232 BM742869 BM853008 AA323650

CA433359 AU131228 BM975549 AA843803 BP355458 BX496012 AA777651 C00200

highest scoring ESTs for EPHA1:

M18391 AU131228 AA158380 AA203510 AA682887 AA772015 AA777651 AA843802 AA843803 AA843957

Unigene Cluster for EPHA1:

EPH receptor A1

Hs.89839 [show with all ESTs]

Unigene Representative Sequence: M18391

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000275815

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

EPHA1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for EPHA1

¹ / ² / ³

3 probe-sets matching EPHA1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
1108_s_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	M18391	1.00	1.00	1.00	1
205977_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_005232	0.60	1.00	0.82	1
205977_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks EPHA1 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: AGGGCTGCAG

SOURCE GeneReport for Unigene cluster: Hs.89839
Expression variation in blood from EXPOLDB for EPHA1
UniProtKB/Swiss-Prot: EPHA1_HUMAN, P21709
Tissue specificity: Overexpressed in several carcinomas

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for EPHA1 gene from 5/6 species (see all 6 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	EPHA1¹	--	EPH receptor A1	86.6(n) 89.26(a)	482735 XM_539851.2 XP_539851.2
chimpanzee (Pan troglodytes)	EPHA1¹	--	EPH receptor A1	99.32(n) 99.39(a)	463808 XM_519451.2 XP_519451.2
cow (Bos taurus)	EPHA1¹	--	EPH receptor A1	86.58(n) 88.73(a)	525946 XM_604305.3 XP_604305.2
rat (Rattus norvegicus)	Epha1¹	--	Eph receptor A1	85.42(n) 88.32(a)	312279 XM_231658.4 XP_231658.3
mouse (Mus musculus)	Epha1^{1, 5}	6⁵	Eph receptor A1^{1, 5}	85.66(n)¹ 88.32(a)¹	13835¹ NM_023580.3¹ NP_076069.2¹ AF131197⁵ AK028478⁵ (see all 8)

About this table Species with no ortholog for EPHA1

ENSEMBL Gene Tree for EPHA1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for EPHA1 gene

EPHA2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/114 NCBI SNPs in EPHA1 are shown (see all 114 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 29)

AB	SNP ID	Valid	Chr 7 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs4725617^1,2	A,C,F,H	142807222(+)	`CAGACG/ACAAGG`	1	V/A	mis¹ ese³		11		EU EA WA NA	954
	rs6967117^1,2	A,C,F,H	142798989(+)	`AGTCAC/TCCTGT`	1	M/V	mis¹		8		EU EA WA	818
	rs11768549^1,2	C,F,H	142805275(+)	`GGTACC/TGTTCT`	1	R/Q	mis¹ ese³		8		EU EA WA	826
	rs12703526^1,2	C,F,H	142817710(+)	`CATCAG/TTTCTT`	1	--	ng3¹		16		EU EA WA NA	1620
	rs7792901^1,2	C,F,H	142817441(+)	`CAGGGG/ATCACA`	1	--	ng3¹		8		EU EA WA	834
--	rs7806047^1,2	A,C	142817006(+)	`tggttC/Gaaacg`	1	--	ng3¹		0	--	--	--	--
	rs34178823^1,2	C,F	142804537(+)	`GGTGGC/TGCGGT`	1	A/T	mis¹		4		EU EA WA	420
--	rs11762262^1,2	C	142817998(+)	`ACACAC/TATTGC`	1	--	ng3¹		0	--	--	--	--
--	rs7792781^1,2	C	142817148(+)	`gacctC/Taggtg`	1	--	ng3¹ tfbs³		0	--	--	--	--
	rs35719334^1,2	C	142804566(+)	`TCTGCT/CGCTGG`	1	Q/R	mis¹		4		EU EA WA	420

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HapMap Linkage Disequilibrium images for EPHA1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 179610

10/13 Novoseek disease relationships for EPHA1 gene (see all 13 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
neovascularization	42.83	4	17260020 (1), 11146556 (1), 12351647 (1), 17049832 (1)
cancer	30.08	13	14767510 (1), 15892616 (1), 16516143 (1), 18797510 (1) (see all 13)
glioblastoma	28.99	1	10064801 (1)
tumors	28.25	23	11146556 (2), 16862074 (2), 18366728 (2), 19144211 (2) (see all 12)
metastasis	15.00	5	17260020 (1), 18797510 (1), 15561600 (1), 19144211 (1)
glioma	14.41	1	15126357 (1)
colorectal cancer	7.38	2	19277044 (2)
breast carcinoma	3.09	1	12209731 (1)
melanoma	0.00	2	12209731 (1), 11870224 (1)
carcinoma	0.00	2	19144211 (1)

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Tumor Gene Database: EPHA1

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/210 PubMed articles for EPHA1 gene (see all 210 ):

Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee. (PubMed id 9267020)^{1, 2, 3} (1997)
A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)^{3, 4} Beausoleil S.A.... Gygi S.P. (2006)
Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules. (PubMed id 15951569)^{3, 4} Zhang Y.... White F.M. (2005)
The DNA sequence of human chromosome 7. (PubMed id 12853948)^{3, 4} Hillier L.W.... Wilson R.K. (2003)
Genomic structure of the EPHA1 receptor tyrosine kinase gene. (PubMed id 10369740)^{3, 4} Owshalimpur D. and Kelley M.J. (1999)
A novel putative tyrosine kinase receptor encoded by the eph gene. (PubMed id 2825356)^{3, 4} Hirai H.... Takaku F. (1987)
Epigenetic silencing of EphA1 expression in colorectal cancer is correlated with poor survival. (PubMed id 19277044)^{1, 3} Herath N.I....Boyd A.W. (2009)
Expression profile of Eph receptors and ephrin ligands in human skin and downregulation of EphA1 in nonmelanoma skin cancer. (PubMed id 16862074)^{1, 3} Hafner C....Vogt T. (2006)
EphA1 interacts with integrin-linked kinase and regulates cell morphology and motility. (PubMed id 19118217)^{1, 3} Yamazaki T....Maru Y. (2009)
Over-expression of Eph and ephrin genes in advanced ovarian cancer: ephrin gene expression correlates with shortened survival. (PubMed id 16737551)^{1, 3} Herath N.I....Boyd A.W. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 2041	HGNC: 3385	AceView: EPHA1	Ensembl:ENSG00000146904	euGenes: HUgn2041
ECgene: EPHA1	H-InvDB: EPHA1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for EPHA1	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for EPHA1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for EPHA1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for EPHA1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for EPHA1		Antibodies for EPHA1
	Explore super-pooled esiRNAs		Proteins for EPHA1
	Lentivirus-delivered shRNAs for EPHA1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (EPHA1)
	Antibodies (EPHA1)
	Chimera RNAi (EPHA1)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Antibodies & Assays for EPHA1

	Recombinant Proteins (Eph receptor A1)
	Antibodies (Eph receptor A1)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for EPHA1

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for EPHA1

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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EPHA1 Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for EPHA1

Summaries
for EPHA1

Genomic Location
for EPHA1

Proteins
for EPHA1

Protein Domains/
Families
for EPHA1

Gene Function
for EPHA1

Pathways & Interactions
for EPHA1

Drugs & Compounds
for EPHA1

Transcripts
for EPHA1

Expression
for EPHA1

Orthologs
for EPHA1

Paralogs
for EPHA1

SNPs/Variants
for EPHA1

Disorders & Mutations
for EPHA1

Medical News
for EPHA1

Publications
for EPHA1

Search for EPHA1

Genome Databases showing EPHA1

Other Databases showing EPHA1

Specialized Databases showing EPHA1

Licensable Technologies
for EPHA1

Services
for EPHA1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

EPHA1 Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor EPHA1

Summariesfor EPHA1

Genomic Locationfor EPHA1

Proteinsfor EPHA1

Protein Domains/Familiesfor EPHA1

Gene Functionfor EPHA1

Pathways & Interactionsfor EPHA1

Drugs & Compoundsfor EPHA1

Transcriptsfor EPHA1

Expression for EPHA1

Orthologsfor EPHA1

Paralogsfor EPHA1

SNPs/Variantsfor EPHA1

Disorders & Mutationsfor EPHA1

Medical Newsfor EPHA1

Publicationsfor EPHA1

Search for EPHA1

Genome Databases showing EPHA1

Other Databases showing EPHA1

Specialized Databases showing EPHA1

Licensable Technologiesfor EPHA1

Servicesfor EPHA1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for EPHA1

Summaries
for EPHA1

Genomic Location
for EPHA1

Proteins
for EPHA1

Protein Domains/
Families
for EPHA1

Gene Function
for EPHA1

Pathways & Interactions
for EPHA1

Drugs & Compounds
for EPHA1

Transcripts
for EPHA1

Expression
for EPHA1

Orthologs
for EPHA1

Paralogs
for EPHA1

SNPs/Variants
for EPHA1

Disorders & Mutations
for EPHA1

Medical News
for EPHA1

Publications
for EPHA1

Licensable Technologies
for EPHA1

Services
for EPHA1