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EPB41L3 Gene

protein-coding GIFtS: 65

GC18M005382

erythrocyte membrane protein band 4.1-like 3
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
4.1B ^¹, ², ³
DAL-1 ^², ³
DAL1 ^¹, ², ³, ⁵
FLJ37633 ^²
KIAA0987 ^¹, ², ³

Descriptions
Differentially expressed in adenocarcinoma of the lung protein 1 ^³
differentially expressed in adenocarcinoma of the lung ^²
erythrocyte membrane protein band 4.1-like 3 ^²

External Ids
HGNC: 3380¹
Entrez Gene: 23136²
UniProtKB: Q9Y2J2³
Ensembl: ENSG00000082397⁷

Search outside databases for aliases for EPB41L3 gene

Previous GC identifers: GC18P005437 GC18M005456

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: E41L3_HUMAN, Q9Y2J2

Function: Critical growth regulator in the pathogenesis of meningiomas

Gene Wiki entry for EPB41L3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the EPB41L3 gene

Entrez Gene cytogenetic band: 18p11.32 Ensembl cytogenetic band: 18p11.31 HGNC cytogenetic band: 18p11.32

EPB41L3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 18 GeneLoc Exon Structure

GeneLoc location for GC18M005382: (about GC identifiers)

Start:	5,382,388 bp from pter
End:	5,620,640 bp from pter
Size:	238,253 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000018.8 NT_010859.14

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: E41L3_HUMAN, Q9Y2J2 (See protein sequence)

Recommended Name: Band 4.1-like protein 3

Size: 1087 amino acids; 120678 Da

Subunit: Interacts with CADM1

Subcellular location: Cytoplasm, cytoskeleton (By similarity)

Sequence caution: Sequence=AAC79806.1; Type=Frameshift; Positions=29, 59;

PDB structure from and Proteopedia :

2HE7 (3D)

3BIN (3D)

Secondary accessions: O95713 Q9BRP5

Alternative splicing: 3 isoforms: Q9Y2J2-1 Q9Y2J2-2 Q9Y2J2-3 (Additional isoforms seem to exist)

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_036439.2

ENSEMBL proteins:

ENSP00000382981 ENSP00000343158 ENSP00000341138

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (EPB41L3)
	Human Recombinant Proteins from Abnova (EPB41L3)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

5 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0005856	cytoskeleton	IEA	--
GO:0005886	plasma membrane	NAS	9892180
GO:0005911	cell-cell junction	IDA	12234973
GO:0019898	extrinsic to membrane	IEA	--

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Antibodies for EPB41L3:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for EPB41L3
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (EPB41L3), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (EPB41L3)
	Novus Biologicals Antibodies for EPB41L3

Assays for EPB41L3:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q9Y2J2

ProtoNet protein and cluster: Q9Y2J2

2 Blocks protein families:

IPB000299 Band 4.1 domain

IPB007477 SAB

UniProtKB/Swiss-Prot: E41L3_HUMAN, Q9Y2J2

Similarity: Contains 1 FERM domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (EPB41L3)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (EPB41L3)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_012307

Applied Biosystems Silencer® siRNAs for EPB41L3

Sigma-Aldrich siRNA for EPB41L3

Sigma-Aldrich shRNA for EPB41L3

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for EPB41L3
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_012307
Myc/DDK tagged cDNA clone in CMV expression vector: NM_012307
untagged cDNA clone in CMV expression vector: NM_012307

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_012307

UniProtKB/Swiss-Prot: E41L3_HUMAN, Q9Y2J2

Function: Critical growth regulator in the pathogenesis of meningiomas

Genatlas biochemistry entry for EPB41L3:

erythrocyte surface protein 4.1-like 3,expressed in the brain

3 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Epb4.1l3):

endocrine/exocrine gland

normal

tumorigenesis

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003779	actin binding	IEA	--
GO:0005198	structural molecule activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Gene Network Central^TM Interacting Genes and Proteins Network for EPB41L3

5/22 Interacting proteins for EPB41L3 (Q9Y2J2^{1, 2} ENSP00000343158³) via UniProtKB, MINT, and/or STRING (see all 22 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
YWHAB	P31946¹^,², ENSP00000361930³	EBI-310986, EBI-359815 MINT-50963 EBI-310986, EBI-359815 MINT-50963 STRING (score=.905)
YWHAG	P61981¹^,², ENSP00000306330³	EBI-310986, EBI-359832 MINT-50838 EBI-310986, EBI-359832 MINT-50838 STRING (score=.735)
YWHAZ	P63104¹^,², ENSP00000309503³	EBI-310986, EBI-347088 MINT-51018 EBI-310986, EBI-347088 MINT-51018 STRING (score=.735)
ABL1	P00519¹	EBI-310986, EBI-375543
CRK	P46108¹	EBI-310986, EBI-886

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2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008150	biological_process	ND	--
GO:0030866	cortical actin cytoskeleton organization	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for EPB41L3
2 Novoseek chemical compound relationships for EPB41L3 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
progesterone	18.10	3	11589430 (1), 11079777 (1)
thymidine	10.94	2	15116094 (1), 15688033 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (EPB41L3)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (EPB41L3)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_012307

Sigma-Aldrich siRNA for EPB41L3

Sigma-Aldrich shRNA for EPB41L3

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_012307

REFSEQ mRNAs for EPB41L3 gene:

NM_012307.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_012307

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_012307
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_012307
                                 untagged cDNA clone in CMV expression vector: NM_012307

Additional cDNA sequence:

AB023204.1 AF069072.1 AF515797.1 AK090875.1 AK094952.1 AK128531.1 AK292583.1 AK294610.1

AK294690.1 AK295453.1 AK297406.1 AK303679.1 AK307751.1 AK307904.1 AK314438.1 AL832598.2

BC006141.1 BC008377.1 BC144531.1

21 DOTS entries:

DT.100811666 DT.100680879 DT.448097 DT.102839096 DT.91651680 DT.100811665 DT.100037099 DT.100760852

DT.121103773 DT.121103834 DT.95255086 DT.100746176 DT.91756598 DT.91756605 DT.97801097 DT.100675153

DT.102839110 DT.121103786 DT.121103787 DT.121103845 DT.86853288

24/188 AceView cDNA sequences (see all 188 ):

NM_012307 CA392588 AA961368 AA137177 CA389788 Z39205 AI004767 AA918413

BU170106 AI089001 AA946867 CA397120 BQ723106 BQ718050 AA926990 AW949363

Z43119 AA969754 BE790193 BQ721327 BG164458 AB023204 AW022746 AA757612

highest scoring ESTs for EPB41L3:

AB023204 AF069072 BC006141 BE798638 AA135872 AA137177 AA173170 AA297012 AA302629 AA307056

Unigene Cluster for EPB41L3:

Erythrocyte membrane protein band 4.1-like 3

Hs.213394 [show with all ESTs]

Unigene Representative Sequence: AL832598

GeneLoc Exon Structure

5/18 Alternative Splicing Database (ASD) splice patterns (SP) for EPB41L3 (see all 18 )

ExUns:	1	^	2	^	3a	·	3b	^	4a	·	4b	^	5	^	6	^	7	^	8	^	9	^	10a	·	10b	^	11	^	12	^	13	^	14	^	15a	·	15b	·	15c	·	15d	·	15e	^	16	^	17a	·	17b	^	18	^
SP1:									-		-		-																																-		-				-
SP2:																																													-		-				-
SP3:									-		-		-												-		-		-		-		-		-		-		-		-		-		-		-		-		-
SP4:																																													-		-				-
SP5:									-		-		-

ExUns:	19a	·	19b	·	19c	^	20a	·	20b	·	20c	^	21	^	22a	·	22b	^	23a	·	23b	·	23c	^	24a	·	24b	^	25a	·	25b	^	26	^	27	^	28a	·	28b	^	29a	·	29b	·	29c	·	29d	·	29e
SP1:					-		-		-		-		-		-		-
SP2:							-		-		-		-		-		-
SP3:	-		-		-		-		-		-		-		-		-		-		-		-		-		-		-		-		-		-		-
SP4:					-		-		-		-				-
SP5:

About this scheme

ECgene alternative splicing isoforms for EPB41L3

3 Ensembl transcripts including schematic representations:

ENST00000400111 ENST00000341928 ENST00000342933

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

EPB41L3 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for EPB41L3

¹ / ² / ³

8 probe-sets matching EPB41L3 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
41385_at²^{, 3}	U95-A	1	1.00	1.00	0.99	0.94	AB023204	1.00	1.00	1.00	1
59615_f_at²^{, 3}	U95-C	1	0.44	1.00	0.98	1.06	AI679988	0.40	1.00	0.76	1
206710_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_012307	0.60	1.00	0.82	1
211776_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	BC006141	0.80	1.00	0.91	1
212681_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AI770004	0.40	1.00	0.76	1
206710_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
211776_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
212681_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks EPB41L3 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GTGAATGTAT

SOURCE GeneReport for Unigene cluster: Hs.213394
Expression variation in blood from EXPOLDB for EPB41L3
UniProtKB/Swiss-Prot: E41L3_HUMAN, Q9Y2J2
Tissue specificity: Expressed at high levels in brain, with lower levels in kidney, intestine, and
testis

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for EPB41L3 gene from 5/10 species (see all 10 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
chimpanzee (Pan troglodytes)	EPB41L3¹	--	erythrocyte membrane protein band 4.1-like 3	99.26(n) 98.9(a)	455309 XM_512036.2 XP_512036.2
cow (Bos taurus)	EPB41L3¹	--	erythrocyte membrane protein band 4.1-like 3	86.7(n) 90.05(a)	532616 XM_865681.2 XP_870774.2
rat (Rattus norvegicus)	Epb4.1l3¹	--	erythrocyte protein band 4.1-like 3	84.62(n) 88.42(a)	116724 NM_053927.1 NP_446379.1
mouse (Mus musculus)	Epb4.1l3^{1, 5}	17 (42.50 cM)⁵	erythrocyte protein band 4.1-like 3^{1, 5}	83.7(n)¹ 88.66(a)¹	13823¹ NM_013813.1¹ NP_038841.1¹ AB370264⁵ AF152247⁵ (see all 22)
chicken (Gallus gallus)	EPB41L3¹	--	erythrocyte membrane protein band 4.1-like 3	77.19(n) 78.99(a)	421055 XM_419142.2 XP_419142.2

About this table Species with no ortholog for EPB41L3

ENSEMBL Gene Tree for EPB41L3

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for EPB41L3 gene

EPB41² EPB41L2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/802 NCBI SNPs in EPB41L3 are shown (see all 802 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 295)

AB	SNP ID	Valid	Chr 18 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs1626709^1,2	A,C,F,H	5535820(+)	`GTTGCG/ATATGA`	1	--	ng3¹		3		EU EA	300
	rs9953490^1,2	A,C,F,H	5382653(+)	`AAAAGT/AAACTA`	1	--	ut3¹		4		EU EA WA	418
	rs8096452^1,2	A,C,F,H	5387323(+)	`CTCCTC/GCACCA`	1	E/Q	mis¹ ese³		7		EU EA WA NA	556
	rs8082898^1,2	C,F,H	5406160(+)	`GTCTGT/CAGCTA`	1	C/Y	mis¹ ese³		11		EU EA WA NA	976
	rs9966357^1,2	C,F,H	5406221(+)	`CAAGGC/TGGGCT`	1	A/T	mis¹		8		EU EA WA	824
--	rs1617446^1,2	A,C	5534785(-)	`actttA/Ctttta`	1	--	ng3¹		0	--	--	--	--
	rs1719968^1,2	A,C	5535836(-)	`TATATA/GTCTCT`	1	--	ng3¹		0	--	--	--	--
	rs1140836^1,2	C,F	5382523(-)	`TTTCCA/CCTGTA`	1	--	ut3¹ ese³		1		MN	184
--	rs3638^1,2	C	5534830(-)	`aaatcC/Tatcct`	1	--	ng3¹		0	--	--	--	--
	rs11873015^1,2	C	5381912(+)	`TTCAAA/CTTCAC`	1	--	ng5¹		1		NA	90

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HapMap Linkage Disequilibrium images for EPB41L3 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 605331

10/13 Novoseek disease relationships for EPB41L3 gene (see all 13 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
meningioma	76.07	34	10888600 (4), 15116094 (3), 15688033 (3), 16707455 (3) (see all 12)
neurofibromatosis type 2	74.63	3	15674477 (1), 15542977 (1), 15535129 (1)
benign meningioma	69.12	1	16707455 (1)
carcinoma non-small cell lung	57.52	4	9892180 (2), 15334060 (1), 10888600 (1)
adenocarcinoma	51.59	15	15837747 (2), 15116094 (1), 17415786 (1), 18554153 (1) (see all 11)
lung tumor	45.11	3	12234973 (2), 15837747 (1)
tumors	41.30	40	11300722 (4), 15837747 (3), 18554153 (2), 12478663 (2) (see all 20)
brain tumors	41.28	4	16420693 (1), 10888600 (1)
neoplastic transformation	41.14	1	15517334 (1)
cancer lung	36.25	13	15837747 (3), 17415786 (2), 12234973 (2), 16205641 (2) (see all 6)

About this table

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/56 PubMed articles for EPB41L3 gene (see all 56 ):

A novel member of the NF2/ERM/4.1 superfamily with growth suppressing properties in lung cancer. (PubMed id 9892180)^{1, 2, 3, 4} Tran Y.K....Newsham I.F. (1999)
Direct association of TSLC1 and DAL-1, two distinct tumor suppressor proteins in lung cancer. (PubMed id 12234973)^{1, 3, 4} Yageta M.... Murakami Y. (2002)
A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)^{3, 4} Beausoleil S.A.... Gygi S.P. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)^{3, 4} Nagase T....Ohara O. (1999)
Four paralogous protein 4.1 genes map to distinct chromosomes in mouse and human. (PubMed id 9828140)^{2, 3} Peters L.L....Conboy J.G. (1998)
Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer. (PubMed id 17260099)^{1, 3} Heller G....Zochbauer-Muller S. (2007)
Promoter methylation of DAL-1/4.1B predicts poor prognosis in non-small cell lung cancer. (PubMed id 15837747)^{1, 3} Kikuchi S....Murakami Y. (2005)
Immunolocalization of protein 4.1B/DAL-1 during neoplastic transformation of mouse and human intestinal epithelium. (PubMed id 15517334)^{1, 3} Ohno N....Ohno S. (2004)
Disruption of 14-3-3 binding does not impair Protein 4.1B growth suppression. (PubMed id 15116094)^{1, 3} Robb V.A....Gutmann D.H. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 23136	HGNC: 3380	AceView: EPB41L3	Ensembl:ENSG00000082397	euGenes: HUgn23136
ECgene: EPB41L3	H-InvDB: EPB41L3

(According to HUGE)
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HUGE: KIAA0987

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for EPB41L3	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for EPB41L3
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for EPB41L3:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for EPB41L3-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
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Antibodies for EPB41L3

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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EPB41L3 Gene at Home site.
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EPB41L3 Gene

protein-coding GIFtS: 65

Aliases &
Descriptions
for EPB41L3

Summaries
for EPB41L3

Genomic Location
for EPB41L3

Proteins
for EPB41L3

Protein Domains/
Families
for EPB41L3

Gene Function
for EPB41L3

Pathways & Interactions
for EPB41L3

Drugs & Compounds
for EPB41L3

Transcripts
for EPB41L3

Expression
for EPB41L3

Orthologs
for EPB41L3

Paralogs
for EPB41L3

SNPs/Variants
for EPB41L3

Disorders & Mutations
for EPB41L3

Medical News
for EPB41L3

Publications
for EPB41L3

Search for EPB41L3

Genome Databases showing EPB41L3

Other Databases showing EPB41L3

Specialized Databases showing EPB41L3

Licensable Technologies
for EPB41L3

Services
for EPB41L3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

EPB41L3 Gene

protein-coding GIFtS: 65

Aliases & Descriptionsfor EPB41L3

Summariesfor EPB41L3

Genomic Locationfor EPB41L3

Proteinsfor EPB41L3

Protein Domains/Familiesfor EPB41L3

Gene Functionfor EPB41L3

Pathways & Interactionsfor EPB41L3

Drugs & Compoundsfor EPB41L3

Transcriptsfor EPB41L3

Expression for EPB41L3

Orthologsfor EPB41L3

Paralogsfor EPB41L3

SNPs/Variantsfor EPB41L3

Disorders & Mutationsfor EPB41L3

Medical Newsfor EPB41L3

Publicationsfor EPB41L3

Search for EPB41L3

Genome Databases showing EPB41L3

Other Databases showing EPB41L3

Specialized Databases showing EPB41L3

Licensable Technologiesfor EPB41L3

Servicesfor EPB41L3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for EPB41L3

Summaries
for EPB41L3

Genomic Location
for EPB41L3

Proteins
for EPB41L3

Protein Domains/
Families
for EPB41L3

Gene Function
for EPB41L3

Pathways & Interactions
for EPB41L3

Drugs & Compounds
for EPB41L3

Transcripts
for EPB41L3

Expression
for EPB41L3

Orthologs
for EPB41L3

Paralogs
for EPB41L3

SNPs/Variants
for EPB41L3

Disorders & Mutations
for EPB41L3

Medical News
for EPB41L3

Publications
for EPB41L3

Licensable Technologies
for EPB41L3

Services
for EPB41L3