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Aliases for EP400P1 Gene

Aliases for EP400P1 Gene

  • EP400 Pseudogene 1 2 3
  • EP400 N-Terminal Like 2 3 5
  • EP400NL 3 5
  • E1A Binding Protein P400 Pseudogene 3

External Ids for EP400P1 Gene

Previous HGNC Symbols for EP400P1 Gene

  • EP400NL

Summaries for EP400P1 Gene

GeneCards Summary for EP400P1 Gene

EP400P1 (EP400 Pseudogene 1) is a Pseudogene.

Additional gene information for EP400P1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for EP400P1 Gene

Genomics for EP400P1 Gene

GeneHancer (GH) Regulatory Elements for EP400P1 Gene

Promoters and enhancers for EP400P1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12I132083 Promoter/Enhancer 1.6 Ensembl ENCODE 608.5 +0.4 393 2.2 HDGF PKNOX1 CLOCK FOXA2 MLX ARID4B SIN3A DMAP1 YY1 POLR2B EP400P1 ENSG00000274670 DDX51 ENSG00000279640
GH12I131927 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 58.6 -155.1 -155060 3.3 HDGF MLX ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B E2F8 ZNF207 PUS1 ENSG00000255992 EP400P1 EP400 GOLGA3 NOC4L ANKLE2 SFSWAP POLE ENSG00000255933
GH12I132597 Enhancer 1.2 Ensembl ENCODE 83.6 +514.0 514031 1.8 HDGF ARNT YBX1 ZNF2 ZNF143 ZNF548 SP3 ZNF662 REST ZNF592 ZNF140 EP400 ZNF84 ZNF268 ZNF891 ZNF26 GOLGA3 ZNF605 ANKLE2 DDX51
GH12I132487 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 27.2 +407.8 407795 9.3 FOXA2 ARID4B NEUROD1 SIN3A ZBTB7B IRF4 ZNF48 TCF12 GLIS2 GATA2 FBRSL1 ZNF140 EP400P1 EP400 ZNF891 GOLGA3 ANKLE2 ZNF26 ENSG00000256875 NOC4L
GH12I132886 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 33.3 +803.7 803719 3.2 HDGF PKNOX1 CLOCK SMAD1 ARID4B SIN3A DMAP1 ZNF2 YY1 CBX5 CHFR LOC101928530 ZNF140 ANKLE2 EP400 ZNF26 ZNF891 EP400P1 GOLGA3 ZNF268
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around EP400P1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for EP400P1 Gene

Genomic Locations for EP400P1 Gene
chr12:132,084,283-132,131,639
(GRCh38/hg38)
Size:
47,357 bases
Orientation:
Plus strand
chr12:132,568,828-132,613,029
(GRCh37/hg19)

Genomic View for EP400P1 Gene

Genes around EP400P1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
EP400P1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for EP400P1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for EP400P1 Gene

Proteins for EP400P1 Gene

Post-translational modifications for EP400P1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for EP400P1 Gene

Domains & Families for EP400P1 Gene

Gene Families for EP400P1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Suggested Antigen Peptide Sequences for EP400P1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with EP400P1: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for EP400P1 Gene

Function for EP400P1 Gene

Phenotypes From GWAS Catalog for EP400P1 Gene

Phenotypes for EP400P1 Gene

genes like me logo Genes that share phenotypes with EP400P1: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for EP400P1 Gene

Localization for EP400P1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for EP400P1 gene
Compartment Confidence
nucleus 2
cytosol 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for EP400P1 Gene

Pathways & Interactions for EP400P1 Gene

SuperPathways for EP400P1 Gene

No Data Available

Interacting Proteins for EP400P1 Gene

Gene Ontology (GO) - Biological Process for EP400P1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for EP400P1 Gene

Drugs & Compounds for EP400P1 Gene

No Compound Related Data Available

Transcripts for EP400P1 Gene

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for EP400P1 Gene

No ASD Table

Relevant External Links for EP400P1 Gene

GeneLoc Exon Structure for
EP400P1
ECgene alternative splicing isoforms for
EP400P1

Expression for EP400P1 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for EP400P1 Gene

Orthologs for EP400P1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for EP400P1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia EP400NL 34
  • 98 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 7 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta dom 34
  • 1 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea ssl-1 34
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SWR1 34
  • 1 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 1 (a)
OneToMany
Species where no ortholog for EP400P1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for EP400P1 Gene

ENSEMBL:
Gene Tree for EP400P1 (if available)
TreeFam:
Gene Tree for EP400P1 (if available)

Paralogs for EP400P1 Gene

No data available for Paralogs for EP400P1 Gene

Variants for EP400P1 Gene

Sequence variations from dbSNP and Humsavar for EP400P1 Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs1000012895 -- 132,088,541(+) C/T intron_variant
rs1000043884 -- 132,101,674(+) G/C intron_variant
rs1000096641 -- 132,107,022(+) A/G intron_variant
rs1000219450 -- 132,085,836(+) G/C intron_variant
rs1000252635 -- 132,083,168(+) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for EP400P1 Gene

Variant ID Type Subtype PubMed ID
dgv103n21 CNV loss 19592680
esv2288713 CNV deletion 18987734
esv2746911 CNV deletion 23290073
esv2746912 CNV deletion 23290073
nsv1041402 CNV gain 25217958
nsv1070570 CNV deletion 25765185
nsv1121492 CNV deletion 24896259
nsv428285 CNV gain 18775914
nsv470333 CNV loss 18288195
nsv473425 CNV novel sequence insertion 20440878
nsv509493 CNV insertion 20534489
nsv826563 CNV gain 20364138

Variation tolerance for EP400P1 Gene

Gene Damage Index Score: 4.62; 65.46% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for EP400P1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
EP400P1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for EP400P1 Gene

Disorders for EP400P1 Gene

Additional Disease Information for EP400P1

No disorders were found for EP400P1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for EP400P1 Gene

Publications for EP400P1 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
  4. A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly. (PMID: 24535457) Chouraki V … Lambert JC (Molecular psychiatry 2014) 3 58
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58

Products for EP400P1 Gene

Sources for EP400P1 Gene

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