Free for academic non-profit institutions. Other users need a Commercial license

Aliases for EP400NL Gene

Aliases for EP400NL Gene

  • EP400 N-Terminal Like 2 3

External Ids for EP400NL Gene

Previous GeneCards Identifiers for EP400NL Gene

  • GC12P131141
  • GC12P132568
  • GC12P129454

Summaries for EP400NL Gene

GeneCards Summary for EP400NL Gene

EP400NL (EP400 N-Terminal Like) is a Pseudogene. An important paralog of this gene is SRCAP.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for EP400NL Gene

Genomics for EP400NL Gene

Regulatory Elements for EP400NL Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for EP400NL Gene

Chromosome:
12
Start:
132,084,283 bp from pter
End:
132,131,639 bp from pter
Size:
47,357 bases
Orientation:
Plus strand

Genomic View for EP400NL Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for EP400NL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for EP400NL Gene

Proteins for EP400NL Gene

  • Protein details for EP400NL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZTU2-E400N_HUMAN
    Recommended name:
    EP400 N-terminal-like protein
    Protein Accession:
    Q6ZTU2
    Secondary Accessions:
    • A6NLB7
    • A8K0Z5
    • B3KQY2
    • Q6NXP1
    • Q8N253
    • Q8N7S7
    • Q9UFJ3

    Protein attributes for EP400NL Gene

    Size:
    488 amino acids
    Molecular mass:
    51753 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAB56026.2; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for EP400NL Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for EP400NL Gene

Proteomics data for EP400NL Gene at MOPED

Post-translational modifications for EP400NL Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for EP400NL Gene

Domains & Families for EP400NL Gene

Protein Domains for EP400NL Gene

ProtoNet:

Suggested Antigen Peptide Sequences for EP400NL Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with EP400NL: view

No data available for Gene Families and UniProtKB/Swiss-Prot for EP400NL Gene

Function for EP400NL Gene

Gene Ontology (GO) - Molecular Function for EP400NL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with EP400NL: view

Phenotypes for EP400NL Gene

GenomeRNAi human phenotypes for EP400NL:
genes like me logo Genes that share phenotypes with EP400NL: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for EP400NL Gene

Localization for EP400NL Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for EP400NL Gene

Pathways & Interactions for EP400NL Gene

SuperPathways for EP400NL Gene

No Data Available

Interacting Proteins for EP400NL Gene

Gene Ontology (GO) - Biological Process for EP400NL Gene

None

No data available for Pathways by source and SIGNOR curated interactions for EP400NL Gene

Drugs & Compounds for EP400NL Gene

No Compound Related Data Available

Transcripts for EP400NL Gene

Unigene Clusters for EP400NL Gene

EP400 N-terminal like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for EP400NL Gene

No ASD Table

Relevant External Links for EP400NL Gene

GeneLoc Exon Structure for
EP400NL
ECgene alternative splicing isoforms for
EP400NL

Expression for EP400NL Gene

mRNA expression in normal human tissues for EP400NL Gene

mRNA differential expression in normal tissues according to GTEx for EP400NL Gene

This gene is overexpressed in Testis (x4.3).

Protein differential expression in normal tissues from HIPED for EP400NL Gene

This gene is overexpressed in Testis (62.2) and CD4 Tcells (6.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for EP400NL Gene



SOURCE GeneReport for Unigene cluster for EP400NL Gene Hs.122115

genes like me logo Genes that share expression patterns with EP400NL: view

Protein tissue co-expression partners for EP400NL Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for EP400NL Gene

Orthologs for EP400NL Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for EP400NL Gene

Organism Taxonomy Gene Similarity Type Details
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 7 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia EP400NL 36
  • 98 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta dom 36
  • 1 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea ssl-1 36
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SWR1 36
  • 1 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 1 (a)
OneToMany
Species with no ortholog for EP400NL:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for EP400NL Gene

ENSEMBL:
Gene Tree for EP400NL (if available)
TreeFam:
Gene Tree for EP400NL (if available)

Paralogs for EP400NL Gene

Paralogs for EP400NL Gene

(1) SIMAP similar genes for EP400NL Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with EP400NL: view

Variants for EP400NL Gene

Sequence variations from dbSNP and Humsavar for EP400NL Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs15882 -- 132,095,913(+) CTGTT(A/C)CCCTG intron-variant
rs1136413 -- 132,095,802(+) TTCCT(A/G)TTCTT intron-variant
rs4072972 -- 132,118,203(-) gcctc(A/G)gcctc intron-variant
rs6598199 -- 132,087,708(+) aaggg(C/T)atgca intron-variant
rs6598200 -- 132,099,641(+) cgcct(A/G)gctaa intron-variant

Structural Variations from Database of Genomic Variants (DGV) for EP400NL Gene

Variant ID Type Subtype PubMed ID
nsv899699 CNV Gain 21882294
dgv1518n71 CNV Loss 21882294
dgv1519n71 CNV Loss 21882294
dgv1520n71 CNV Loss 21882294
nsv899720 CNV Loss 21882294
dgv1521n71 CNV Loss 21882294
nsv428285 CNV Gain 18775914
dgv1522n71 CNV Loss 21882294
esv2746911 CNV Deletion 23290073
esv2288713 CNV Deletion 18987734
esv2746912 CNV Deletion 23290073
dgv1523n71 CNV Loss 21882294
dgv1524n71 CNV Loss 21882294
nsv509493 CNV Insertion 20534489
nsv470333 CNV Loss 18288195
dgv103n21 CNV Loss 19592680
nsv826563 CNV Gain 20364138
nsv899739 CNV Loss 21882294
nsv899740 CNV Loss 21882294
dgv1525n71 CNV Loss 21882294
nsv899743 CNV Loss 21882294

Variation tolerance for EP400NL Gene

Gene Damage Index Score: 4.62; 65.46% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for EP400NL Gene

HapMap Linkage Disequilibrium report
EP400NL

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for EP400NL Gene

Disorders for EP400NL Gene

Relevant External Links for EP400NL

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
EP400NL
genes like me logo Genes that share disorders with EP400NL: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for EP400NL Gene

Publications for EP400NL Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. A genome-wide association meta-analysis of plasma AI^ peptides concentrations in the elderly. (PMID: 24535457) Chouraki V. … Lambert J.C. (Mol. Psychiatry 2014) 67
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 67

Products for EP400NL Gene

Sources for EP400NL Gene

Back to Top

Content