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EOGT Gene

protein-coding   GIFtS: 44
GCID: GC03M069025

EGF Domain-Specific O-Linked N-Acetylglucosamine (GlcNAc)...

(Previous name: chromosome 3 open reading frame 64)
(Previous symbol: C3orf64)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
EGF Domain-Specific O-Linked N-Acetylglucosamine (GlcNAc)
Transferase1 2
     AOS42 5
C3orf641 2 3 5     Chromosome 3 Open Reading Frame 641
EOGT12 3 5     EGF Domain-Specific O-Linked N-Acetylglucosamine Transferase2
AER61 Glycosyltransferase1 2     EGF-O-GlcNAc Transferase2
Extracellular O-Linked N-Acetylglucosamine Transferase2 3     EC 2.4.1.2553
AER612 3     

External Ids:    HGNC: 285261   Entrez Gene: 2852032   Ensembl: ENSG000001633787   OMIM: 6147895   UniProtKB: Q5NDL23   

Export aliases for EOGT gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for EOGT Gene:
EOGT (EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase) is a protein-coding gene. Diseases associated with EOGT include adams-oliver syndrome 4, and adams-oliver syndrome 3. GO annotations related to this gene include protein N-acetylglucosaminyltransferase activity. An important paralog of this gene is POMGNT2.

UniProtKB/Swiss-Prot: EOGT_HUMAN, Q5NDL2
Function: Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue
in extracellular proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc).
Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded
EGF-like domains (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NT_022517.19  NC_018914.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for EOGT
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for EOGT

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat EOGT


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p14.1   Ensembl cytogenetic band:  3p14.1   HGNC cytogenetic band: 3p14.1

EOGT Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
EOGT gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M069025:  view genomic region     (about GC identifiers)

Start:
69,024,365 bp from pter      End:
69,063,112 bp from pter
Size:
38,748 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: EOGT_HUMAN, Q5NDL2 (See protein sequence)
Recommended Name: EGF domain-specific O-linked N-acetylglucosamine transferase precursor  
Size: 527 amino acids; 62011 Da
Secondary accessions: Q6MZY0 Q6P985 Q6ZTV0
Alternative splicing: 3 isoforms:  Q5NDL2-1   Q5NDL2-2   Q5NDL2-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for EOGT: NX_Q5NDL2

Explore proteomics data for EOGT at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn354

  • See EOGT Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001265618.1  NP_775925.1  

    ENSEMBL proteins: 
     ENSP00000373206   ENSP00000295571   ENSP00000384124   ENSP00000408090   ENSP00000411832  
     ENSP00000443780   ENSP00000444264  

    EOGT Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR007657 Glycosyltransferase_AER61

    Graphical View of Domain Structure for InterPro Entry Q5NDL2

    ProtoNet protein and cluster: Q5NDL2

    UniProtKB/Swiss-Prot: EOGT_HUMAN, Q5NDL2
    Similarity: Belongs to the glycosyltransferase 61 family


    EOGT for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: EOGT_HUMAN, Q5NDL2
    Function: Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue
    in extracellular proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc).
    Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded
    EGF-like domains (By similarity)
    Catalytic activity: UDP-N-acetyl-D-glucosamine + [protein]-L-serine = UDP +
    [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine
    Catalytic activity: UDP-N-acetyl-D-glucosamine + [protein]-L-threonine = UDP +
    [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine

         Enzyme Number (IUBMB): EC 2.4.1.2551

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016262protein N-acetylglucosaminyltransferase activity ISS--
    GO:0016757transferase activity, transferring glycosyl groups ----
         
    EOGT for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for EOGT:
     G0/1 arrest  Increased G1 DNA content  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for EOGT
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    miRNA
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    miRTarBase miRNAs that target EOGT:
    hsa-mir-132-3p (MIRT021748), hsa-mir-155-5p (MIRT020654), hsa-mir-124-3p (MIRT022493), hsa-mir-192-5p (MIRT026413), hsa-mir-9-5p (MIRT021350)

    Block miRNA regulation of human, mouse, rat EOGT using miScript Target Protectors
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    SwitchGear 3'UTR luciferase reporter plasmidEOGT 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat EOGT

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EOGT


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    EOGT_HUMAN, Q5NDL2: Endoplasmic reticulum lumen (By similarity)

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005788endoplasmic reticulum lumen IEA--

    EOGT for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for EOGT About    
    See pathways by source

    SuperPathContained pathways About
    1Other types of O-glycan biosynthesis
    Other types of O-glycan biosynthesis

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for EOGT):
        Other types of O-glycan biosynthesis


    EOGT for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for EOGT
    Interactions:

        Search GeneGlobe Interaction Network for EOGT

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for EOGT (ENSP000002955714) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYH10ENSP000002692434STRING: ENSP00000269243
    MYH11ENSP000003796164STRING: ENSP00000379616
    MYH9ENSP000002161814STRING: ENSP00000216181
    CGNENSP000002716364STRING: ENSP00000271636
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006493protein O-linked glycosylation ISS--
    GO:0008152metabolic process ----

    EOGT for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for EOGT



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for EOGT gene (2 alternative transcripts): 
    NM_001278689.1  NM_173654.2  

    Unigene Cluster for EOGT:

    EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
    Hs.518059  [show with all ESTs]
    Unigene Representative Sequence: BX648818
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000383701(uc003dnl.3 uc011bfw.2 uc003dnm.1) ENST00000295571(uc003dnk.3)
    ENST00000496647(uc003dnj.3) ENST00000403140 ENST00000480846 ENST00000424374
    ENST00000456376 ENST00000540764 ENST00000540955
    miRNA
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    Block miRNA regulation of human, mouse, rat EOGT using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate EOGT
    SwitchGear 3'UTR luciferase reporter plasmidEOGT 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat EOGT
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    GenScript Custom all cDNA clones Services for EOGT
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for EOGT
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat EOGT
    Primer
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    OriGene qPCR primer pairs and template standards for EOGT
    OriGene qSTAR qPCR primer pairs in human, mouse for EOGT
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat EOGT
      QuantiTect SYBR Green Assays in human, mouse, rat EOGT
      QuantiFast Probe-based Assays in human, mouse, rat EOGT

    Additional mRNA sequence: 

    AJ868234.1 AK091089.1 AK123213.1 AK126187.1 AK290356.1 AK294101.1 AK304102.1 AL833467.1 
    BC028935.1 BC060887.1 BX640821.1 BX648818.1 KC347596.1 

    8 DOTS entries:

    DT.101982765  DT.100715361  DT.101965379  DT.411622  DT.95159140  DT.102822548  DT.95123788  DT.97824659 

    Selected AceView cDNA sequences (see all 73):

    BX092228 AK091089 AI554339 BU159745 AA298169 CB157369 CD676955 BU685915 
    AK023140 CB242424 NM_173654 BC060887 CB321975 BX648818 BQ218677 CB243059 
    BX399512 AX746774 AI332513 AI868024 BQ016149 AI819191 AK123213 BX489762 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for EOGT (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b · 16c ^ 17a · 17b ^ 18 ^ 19 ^
    SP1:                          -                                                                 -                       -                       -               
    SP2:                          -                                                                 -     -     -     -     -                       -               
    SP3:                                                                          -     -                                   -                                       
    SP4:                                                                                            -                       -                       -               
    SP5:                    -     -                                                                                                                                 

    ExUns: 20
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for EOGT

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    EOGT expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    EOGT Expression
    About this image


    EOGT expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 4 entries
             Metencephalon
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Medulla Oblongata
     
     Heart (Cardiovascular System)
             Dorsal Aorta
    EOGT Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    EOGT Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.518059
        Custom PCR Arrays for EOGT
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EOGT

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for EOGT gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Eogt1 , 5 RIKEN cDNA A130022J15 gene5
    EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) more1
    84.82(n)1
    87.86(a)1
      6 (44.88 cM)5
    1013511  NM_175313.41  NP_780522.11 
     971100245 
    chicken
    (Gallus gallus)
    Aves C3ORF641 chromosome 12 open reading frame, human C3orf64 74.58(n)
    78.54(a)
      426961  NM_001031409.1  NP_001026580.1 
    lizard
    (Anolis carolinensis)
    Reptilia EOGT6
    EGF domain-specific O-linked N-acetylglucosamine (...
    50(a)
    1 ↔ 1
    2(182400926-182428216)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.71602 Xenopus laevis transcribed sequence with weak similarity more 73.58(n)    BG346696.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC7980871 EGF domain-specific O-linked N-acetylglucosamine transferase-like 64.74(n)
    66.28(a)
      798087  XM_005155820.1  XP_005155877.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Eogt1 EGF-domain O-GlcNAc transferase 53.32(n)
    50.9(a)
      33424  NM_001273005.1  NP_001259934.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_H12D21.101 CELE_H12D21.10 51.99(n)
    44.44(a)
      179990  NM_074276.5  NP_506677.3 


    ENSEMBL Gene Tree for EOGT (if available)
    TreeFam Gene Tree for EOGT (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for EOGT gene
    POMGNT22  

    EOGT for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for EOGT (see all 1028)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0700914
    Adams-Oliver syndrome 4 (AOS4)4--see VAR_0700912 R Q mis40--------
    VAR_0700904
    Adams-Oliver syndrome 4 (AOS4)4--see VAR_0700902 W S mis40--------
    rs615689491,2
    C,F--69023882(+) TTACTA/GAATGA 1 -- int16Minor allele frequency- G:0.23NA WA EA 364
    rs603597891,2
    C--69023919(+) GTGAAC/TATGGA 1 -- int14Minor allele frequency- T:0.22NA WA EA 360
    rs584176641,2
    C,F--69023920(+) TGAACA/GTGGAA 1 -- int13Minor allele frequency- G:0.24WA NA EA 358
    rs1380799621,2
    C--69024002(+) CGAATA/GGAAGA 1 -- int10--------
    rs1843712961,2
    --69024010(+) AGACTA/GTGAAC 1 -- int10--------
    rs1877309561,2
    --69024015(+) GTGAAC/GGTGGA 1 -- int10--------
    rs1925706991,2
    --69024044(+) TTCAGA/GGAAGT 1 -- int10--------
    rs1425699651,2
    --69024056(+) CCATAA/TCTTCC 1 -- int10--------

    HapMap Linkage Disequilibrium report for EOGT (69024365 - 69063112 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for EOGT: --
    Human Gene Mutation Database (HGMD): EOGT
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing EOGT
    DNA2.0 Custom Variant and Variant Library Synthesis for EOGT

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614789   
    OMIM disorders: 615297  
    UniProtKB/Swiss-Prot: EOGT_HUMAN, Q5NDL2
  • Adams-Oliver syndrome 4 (AOS4) [MIM:615297]: A form of Adams-Oliver syndrome, a disorder characterized by
    the congenital absence of skin (aplasia cutis congenita) in combination with transverse limb defects. Aplasia
    cutis congenita can be located anywhere on the body, but in the vast majority of the cases, it is present on the
    posterior parietal region where it is often associated with an underlying defect of the parietal bones. Limb
    abnormalities are typically limb truncation defects affecting the distal phalanges or entire digits (true
    ectrodactyly). Only rarely, metatarsals/metacarpals or more proximal limb structures are also affected. Apart
    from transverse limb defects, syndactyly, most commonly of second and third toes, can also be observed. The
    clinical features are highly variable and can also include cardiovascular malformations, brain abnormalities and
    vascular defects such as cutis marmorata and dilated scalp veins. Note=The disease is caused by mutations
    affecting the gene represented in this entry

  • 6 diseases for EOGT:    
    About MalaCards
    adams-oliver syndrome 4    adams-oliver syndrome 3    adams-oliver syndrome 1    oliver syndrome
    adams oliver syndrome    meningitis


    EOGT for disorders           About GeneDecksing


    Export disorders for EOGT gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for EOGT gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with EOGT)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mutations in EOGT confirm the genetic heterogeneity of autosomal-recessive Adams-Oliver syndrome. (PubMed id 23522784)1, 2 Shaheen R....Alkuraya F.S. (Am. J. Hum. Genet. 2013)
    2. O-linked-N-acetylglucosamine modification of mammalian Notch receptors by an atypical O-GlcNAc transferase Eogt1. (PubMed id 22310717)1, 3 Sakaidani Y....Okajima T. (Biochem. Biophys. Res. Commun. 2012)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. The EGF Repeat-Specific O-GlcNAc-Transferase Eogt Interacts with Notch Signaling and Pyrimidine Metabolism Pathways in Drosophila. (PubMed id 23671640)1 Muller R.... Stanley P. (PLoS ONE 2013)
    5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    6. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    7. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    8. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
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      Query String
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    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 285203 HGNC: 28526 AceView: MGC34132 Ensembl:ENSG00000163378 euGenes: HUgn285203
    ECgene: EOGT Kegg: 285203 H-InvDB: EOGT

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for EOGT Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for EOGT gene:
    Search GeneIP for patents involving EOGT

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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