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Aliases for ENSG00000264813 Gene

Aliases for ENSG00000264813 Gene

  • AC113554.2 5

External Ids for ENSG00000264813 Gene

Previous GeneCards Identifiers for ENSG00000264813 Gene

  • GC17P061562

Summaries for ENSG00000264813 Gene

GeneCards Summary for ENSG00000264813 Gene

ENSG00000264813 is a Protein Coding gene. Diseases associated with ENSG00000264813 include Pancreas Lymphoma and Loeffler Syndrome. GO annotations related to this gene include metallopeptidase activity and peptidyl-dipeptidase activity. An important paralog of this gene is ACE.

Additional gene information for ENSG00000264813 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ENSG00000264813 Gene

Genomics for ENSG00000264813 Gene

Regulatory Elements for ENSG00000264813 Gene

Enhancers for ENSG00000264813 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17H063484 0.6 ENCODE 0.7 +0.1 62 0 CTCF GTF2F1 MAZ TFAP4 ZNF687 RAD21 RFX5 NFYB CREB1 CYB561 DCAF7 TACO1 ENSG00000264813 ACE3P
GH17H063497 0.9 Ensembl ENCODE 0.4 +13.8 13823 2 CTCF PKNOX1 TFE3 FOXA2 ZNF384 RAD21 ZIC2 THRB GLIS2 GLIS1 KCNH6 ACE ACE3P ENSG00000264813
GH17H063503 0.5 ENCODE 0.4 +18.7 18702 0 ZNF217 SMARCE1 ZNF687 DPF2 ACE3P ENSG00000264813
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ENSG00000264813 on UCSC Golden Path with GeneCards custom track

Genomic Location for ENSG00000264813 Gene

Chromosome:
17
Start:
63,484,823 bp from pter
End:
63,521,848 bp from pter
Size:
37,026 bases
Orientation:
Plus strand

Genomic View for ENSG00000264813 Gene

Genes around ENSG00000264813 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ENSG00000264813 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ENSG00000264813 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for ENSG00000264813 Gene

Proteins for ENSG00000264813 Gene

  • Protein details for ENSG00000264813 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    F6X3S4
    Recommended name:
    Angiotensin-converting enzyme
    Protein Accession:
    F6X3S4
    Secondary Accessions:
    • L7MUH0

    Protein attributes for ENSG00000264813 Gene

    Size:
    739 amino acids
    Molecular mass:
    83989 Da
    Cofactor:
    Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
    Quaternary structure:
    No Data Available

neXtProt entry for ENSG00000264813 Gene

Post-translational modifications for ENSG00000264813 Gene

No Post-translational modifications

Other Protein References for ENSG00000264813 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for ENSG00000264813 Gene

Domains & Families for ENSG00000264813 Gene

Protein Domains for ENSG00000264813 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ENSG00000264813: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ENSG00000264813 Gene

Function for ENSG00000264813 Gene

Gene Ontology (GO) - Molecular Function for ENSG00000264813 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004180 carboxypeptidase activity IEA --
GO:0008233 peptidase activity IEA --
GO:0008237 metallopeptidase activity IEA --
GO:0008241 peptidyl-dipeptidase activity IEA --
GO:0016787 hydrolase activity IEA --
genes like me logo Genes that share ontologies with ENSG00000264813: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ENSG00000264813 Gene

Localization for ENSG00000264813 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ENSG00000264813 gene
Compartment Confidence
plasma membrane 2
extracellular 2
cytoskeleton 2
mitochondrion 2
nucleus 2
cytosol 2
peroxisome 1

Gene Ontology (GO) - Cellular Components for ENSG00000264813 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with ENSG00000264813: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for ENSG00000264813 Gene

Pathways & Interactions for ENSG00000264813 Gene

SuperPathways for ENSG00000264813 Gene

No Data Available

Interacting Proteins for ENSG00000264813 Gene

Gene Ontology (GO) - Biological Process for ENSG00000264813 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006508 proteolysis IEA --
genes like me logo Genes that share ontologies with ENSG00000264813: view

No data available for Pathways by source and SIGNOR curated interactions for ENSG00000264813 Gene

Drugs & Compounds for ENSG00000264813 Gene

No Compound Related Data Available

Transcripts for ENSG00000264813 Gene

mRNA/cDNA for ENSG00000264813 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ENSG00000264813 Gene

No ASD Table

Relevant External Links for ENSG00000264813 Gene

GeneLoc Exon Structure for
ENSG00000264813

Expression for ENSG00000264813 Gene

Evidence on tissue expression from TISSUES for ENSG00000264813 Gene

  • Blood(3.1)
  • Heart(3)
  • Kidney(2.6)
  • Muscle(2.6)
  • Nervous system(2.2)
  • Urine(2)
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ENSG00000264813 Gene

Orthologs for ENSG00000264813 Gene

This gene was present in the common ancestor of animals.

Orthologs for ENSG00000264813 Gene

Organism Taxonomy Gene Similarity Type Details
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 56 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia ACE 34
  • 47 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 34
  • 42 (a)
OneToMany
cow
(Bos Taurus)
Mammalia ACE 34
  • 41 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Ace 34
  • 39 (a)
OneToMany
chicken
(Gallus gallus)
Aves ACE 34
  • 33 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 32 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii ace 34
  • 31 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta Ance 34
  • 43 (a)
ManyToMany
Acer 34
  • 39 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea acn-1 34
  • 20 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 53 (a)
ManyToMany
-- 34
  • 46 (a)
ManyToMany
-- 34
  • 28 (a)
ManyToMany
-- 34
  • 22 (a)
ManyToMany
Species where no ortholog for ENSG00000264813 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ENSG00000264813 Gene

ENSEMBL:
Gene Tree for ENSG00000264813 (if available)
TreeFam:
Gene Tree for ENSG00000264813 (if available)

Paralogs for ENSG00000264813 Gene

Paralogs for ENSG00000264813 Gene

genes like me logo Genes that share paralogs with ENSG00000264813: view

Variants for ENSG00000264813 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for ENSG00000264813 Gene

Disorders for ENSG00000264813 Gene

MalaCards: The human disease database

(19) MalaCards diseases for ENSG00000264813 Gene - From: DISEASES

Disorder Aliases PubMed IDs
pancreas lymphoma
  • lymphoma of pancreas
loeffler syndrome
  • loeffler's pneumonia
hypersensitivity reaction type iv disease
  • immunoproliferative disease
urinary system disease
  • non-neoplastic urinary tract disease
fiedler's myocarditis
  • fiedler myocarditis
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with ENSG00000264813: view

No data available for UniProtKB/Swiss-Prot , Genatlas and External Links for ENSG00000264813 Gene

Publications for ENSG00000264813 Gene

No publications were found for ENSG00000264813 Gene.

Products for ENSG00000264813 Gene

Sources for ENSG00000264813 Gene

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