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Aliases for ENSG00000250264 Gene

Aliases for ENSG00000250264 Gene

  • AL669918.1 5

External Ids for ENSG00000250264 Gene

Previous GeneCards Identifiers for ENSG00000250264 Gene

  • GC06M032784

Summaries for ENSG00000250264 Gene

GeneCards Summary for ENSG00000250264 Gene

ENSG00000250264 is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include ATPase activity and MHC protein binding. An important paralog of this gene is TAP2.

Additional gene information for ENSG00000250264 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ENSG00000250264 Gene

Genomics for ENSG00000250264 Gene

GeneHancer (GH) Regulatory Elements for ENSG00000250264 Gene

Promoters and enhancers for ENSG00000250264 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06I032940 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 11.6 -105.4 -105375 8.8 HDGF ATF1 ARID4B ZNF2 IRF4 BRCA1 ZNF207 ZNF143 ATF7 FOS HLA-DMB HLA-DMA BRD2 PSMB9 TAP1 TAP2 PSMB8 RING1 HLA-DOB ENSG00000223837
GH06I032984 Enhancer 1.3 Ensembl ENCODE dbSUPER 11.1 -146.1 -146065 1.3 PKNOX1 CLOCK ATF1 ARID4B SIN3A ZNF2 IRF4 GLIS2 ARID2 ZNF143 HLA-DMB RING1 ENSG00000250264 TAP2 TAP1 PSMB9 HSD17B8 RXRB SLC39A7 RNY4P10
GH06I032982 Enhancer 1.1 Ensembl ENCODE dbSUPER 11.1 -144.7 -144706 1.4 FOXA2 CEBPG BMI1 FEZF1 ZNF664 POLR2A NFATC1 ZSCAN5C PRDM10 BCLAF1 HLA-DMA HLA-DMB ENSG00000250264 TAP2 TAP1 PSMB9 RNY4P10 RXRB SLC39A7 HSD17B8
GH06I032983 Enhancer 0.9 ENCODE dbSUPER 11.1 -143.7 -143737 0.2 KLF1 ZBTB6 ZNF449 CEBPG BMI1 FEZF1 BCL11B POLR2B POLR2A SCRT2 HLA-DMB ENSG00000250264 TAP2 TAP1 PSMB9 RNY4P10 RXRB SLC39A7 MIR219A1 HSD17B8
GH06I032950 Enhancer 0.9 Ensembl ENCODE dbSUPER 11.1 -111.4 -111420 0.3 SCRT1 SCRT2 CREB1 ATF2 SPI1 TAP1 PSMB9 TAP2 ENSG00000250264 HLA-DRB1 ENSG00000248993 HLA-DMB HLA-DMA GC06M032900
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ENSG00000250264 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ENSG00000250264 Gene

Genomic Locations for ENSG00000250264 Gene
chr6:32,813,767-32,838,822
(GRCh38/hg38)
Size:
25,056 bases
Orientation:
Minus strand
chr6:32,781,544-32,806,599
(GRCh37/hg19)

Genomic View for ENSG00000250264 Gene

Genes around ENSG00000250264 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ENSG00000250264 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ENSG00000250264 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for ENSG00000250264 Gene

Proteins for ENSG00000250264 Gene

  • Protein details for ENSG00000250264 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    E7ENX8
    Recommended name:
    Uncharacterized protein
    Protein Accession:
    E7ENX8

    Protein attributes for ENSG00000250264 Gene

    Size:
    843 amino acids
    Molecular mass:
    92999 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ENSG00000250264 Gene

Post-translational modifications for ENSG00000250264 Gene

No Post-translational modifications

Other Protein References for ENSG00000250264 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for ENSG00000250264 Gene

Domains & Families for ENSG00000250264 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ENSG00000250264: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ENSG00000250264 Gene

Function for ENSG00000250264 Gene

Phenotypes From GWAS Catalog for ENSG00000250264 Gene

Gene Ontology (GO) - Molecular Function for ENSG00000250264 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005524 ATP binding IEA --
GO:0015197 peptide transporter activity IEA --
GO:0015440 peptide-transporting ATPase activity IEA --
GO:0016887 ATPase activity IEA --
GO:0042287 MHC protein binding IEA --
genes like me logo Genes that share ontologies with ENSG00000250264: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ENSG00000250264 Gene

Localization for ENSG00000250264 Gene

Subcellular locations from the

Human Protein Atlas (HPA)
  • Endoplasmic reticulum (2)
  • Nuclear speckles (1)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ENSG00000250264 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum IDA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0016607 nuclear speck IDA --
GO:0030176 integral component of endoplasmic reticulum membrane IEA --
genes like me logo Genes that share ontologies with ENSG00000250264: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for ENSG00000250264 Gene

Pathways & Interactions for ENSG00000250264 Gene

SuperPathways for ENSG00000250264 Gene

No Data Available

Interacting Proteins for ENSG00000250264 Gene

Gene Ontology (GO) - Biological Process for ENSG00000250264 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002376 immune system process IEA --
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II IEA --
GO:0006955 immune response IEA --
GO:0015833 peptide transport IEA --
GO:0019882 antigen processing and presentation IEA --
genes like me logo Genes that share ontologies with ENSG00000250264: view

No data available for Pathways by source and SIGNOR curated interactions for ENSG00000250264 Gene

Drugs & Compounds for ENSG00000250264 Gene

No Compound Related Data Available

Transcripts for ENSG00000250264 Gene

mRNA/cDNA for ENSG00000250264 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ENSG00000250264 Gene

No ASD Table

Relevant External Links for ENSG00000250264 Gene

GeneLoc Exon Structure for
ENSG00000250264

Expression for ENSG00000250264 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ENSG00000250264 Gene

mRNA expression in normal human tissues for ENSG00000250264 Gene
genes like me logo Genes that share expression patterns with ENSG00000250264: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ENSG00000250264 Gene

Orthologs for ENSG00000250264 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ENSG00000250264 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 34
  • 95 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 34
  • 75 (a)
ManyToMany
TAP2 34
  • 71 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia TAP2 34
  • 75 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Tap2 34
  • 74 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 68 (a)
ManyToMany
-- 34
  • 64 (a)
ManyToMany
-- 34
  • 63 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 57 (a)
OneToMany
chicken
(Gallus gallus)
Aves TAP2 34
  • 49 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 53 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii abcb3l1 34
  • 41 (a)
ManyToMany
si:dkey-57h18.2 34
  • 37 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea haf-2 34
  • 30 (a)
ManyToMany
haf-9 34
  • 30 (a)
ManyToMany
haf-8 34
  • 29 (a)
ManyToMany
haf-4 34
  • 28 (a)
ManyToMany
haf-7 34
  • 25 (a)
ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes MDL1 34
  • 25 (a)
ManyToMany
MDL2 34
  • 25 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 31 (a)
ManyToMany
CSA.2338 34
  • 30 (a)
ManyToMany
Species where no ortholog for ENSG00000250264 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ENSG00000250264 Gene

ENSEMBL:
Gene Tree for ENSG00000250264 (if available)
TreeFam:
Gene Tree for ENSG00000250264 (if available)

Paralogs for ENSG00000250264 Gene

Paralogs for ENSG00000250264 Gene

genes like me logo Genes that share paralogs with ENSG00000250264: view

Variants for ENSG00000250264 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for ENSG00000250264 Gene

Disorders for ENSG00000250264 Gene

No disorders were found for ENSG00000250264 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for ENSG00000250264 Gene

Publications for ENSG00000250264 Gene

No publications were found for ENSG00000250264 Gene.

Products for ENSG00000250264 Gene

Sources for ENSG00000250264 Gene

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