ENSG00000250264 Gene
protein-coding GIFtS: 12
GCID: GC06M032785 (predicted)
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ENSG00000250264
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Aliases
for ENSG00000250264 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
Export aliases for ENSG00000250264 gene to outside databasesPrevious GC identifer: GC06M032784 |
Summaries
for ENSG00000250264 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ENSG00000250264 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ENSG00000250264
Other transcription factors
Search SABiosciences Chromatin IP Primers for ENSG00000250264
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ENSG00000250264 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Ensembl cytogenetic band: 6p21.32 ENSG00000250264 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06M032785: view genomic region
(about GC identifiers)
Start:
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32,781,544 bp from pter |
End:
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32,806,599 bp from pter |
Size:
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25,056 bases |
Orientation:
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minus strand |
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Proteins
for ENSG00000250264 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB/TrEMBL: E7EUZ6 (See
protein sequence)Recommended Name: Antigen peptide transporter 2 Size: 769 amino acids; 84731 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered aspreliminary dataUniProtKB/TrEMBL: E7ENX8 (See
protein sequence) Recommended Name: Uncharacterized protein Size: 843 amino acids; 92999 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered aspreliminary dataUniProtKB/TrEMBL: B6VNV2 (See
protein sequence) Recommended Name: Truncated antigen peptide transporter 2 Size: 209 amino acids; 22450 DaENSG00000250264 Protein expression data from MOPED and PaxDb: --
ENSEMBL proteins: ENSP00000391806
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
ENSG00000250264 for ontologies About GeneDecksing
ENSG00000250264 Antibody Products:
Assay Products for ENSG00000250264: |
Protein
Domains /
Families
for ENSG00000250264 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
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ENSG00000250264 for domains About GeneDecksing
5/15 InterPro domains/families (see all 15):Graphical View of Domain Structure for InterPro Entry E7EUZ6Graphical View of Domain Structure for InterPro Entry E7ENX8Graphical View of Domain Structure for InterPro Entry B6VNV2ProtoNet protein and cluster: E7EUZ6 UniProtKB/TrEMBL: E7ENX8 Similarity: Contains 1 Ig-like C1-type (immunoglobulin-like) domain |
Function
for ENSG00000250264 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
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| GO:0005524 | ATP binding |
-- | -- | | GO:0015197 | peptide transporter activity |
-- | -- | | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances |
-- | -- |
ENSG00000250264 for ontologies About GeneDecksing
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Pathways & Interactions
for ENSG00000250264 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ENSG00000250264
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0002504 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II |
-- | -- | | GO:0006955 | immune response |
-- | -- |
ENSG00000250264 for ontologies About GeneDecksing
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Drugs & Compounds
for ENSG00000250264 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
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 Browse Tocris compounds for ENSG00000250264
Search CenterWatch for drugs/clinical trials and news about ENSG00000250264 
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Transcripts
for ENSG00000250264 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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1 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000452392(uc011dqf.1)
GeneLoc Exon Structure
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Expression
for ENSG00000250264 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ENSG00000250264 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image SABiosciences Custom PCR Arrays for ENSG00000250264
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat ENSG00000250264 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ENSG00000250264 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ENSG00000250264 |
Orthologs
for ENSG00000250264 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of eukaryotes.
Orthologs for ENSG00000250264 gene from 5/12 species (see all 12) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
51(a) |
1 → many |
GL344036.1(47936-69742) |
zebrafish
(Danio rerio) |
Actinopterygii |
abcb3l16BX324231.16 |
-- |
41(a)36(a) |
many ↔ manymany ↔ many |
19(7746873-7753954) 12(28118319-28129069) |
worm
(Caenorhabditis elegans) |
Secernentea |
haf-86haf-76 |
HAlF transporter (PGP related) family member (haf-...HAlF transporter (PGP related) family member (haf-... |
26(a)20(a) |
possible orthologpossible ortholog |
IV(14694001-14699909) V(14773342-14777316) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
ATTAP16 |
ABC transporter B family member 26 |
26(a) |
1 → many |
1(26621961-26626503) |
rice
(Oryza sativa) |
Liliopsida |
-- |
antigen peptide transporter-like 1, chloroplast pr... |
33(a) |
1 → many |
1(39702262-39707007) |
ENSEMBL Gene Tree for ENSG00000250264 (if available)
TreeFam Gene Tree for ENSG00000250264 (if available) |
Paralogs
for ENSG00000250264 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ENSG00000250264 gene
- TAP22 ABCB102 TAP12 ABCB92 ABCB82
ENSG00000250264 for paralogs About GeneDecksing
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Genomic Variants
for ENSG00000250264 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for ENSG00000250264 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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ENSG00000250264 for disorders About GeneDecksing
3  diseases for ENSG00000250264: About MalaCardspneumonia tuberculosis mycobacterium tuberculosis
Export disorders for ENSG00000250264 gene to outside databases
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Publications
for ENSG00000250264 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
| -- |
External Searches for ENSG00000250264 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing ENSG00000250264 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing ENSG00000250264 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ENSG00000250264 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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About This Section
| Patent Information for ENSG00000250264 gene:
Search GeneIP for patents involving ENSG00000250264
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ENSG00000250264 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ENSG00000250264 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ENSG00000250264 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ENSG00000250264 | | | Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ENSG00000250264 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ENSG00000250264 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ENSG00000250264 |
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 | | | | |  |  |  | | | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ENSG00000250264 |
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