Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ENSG00000250264 Gene

Aliases for ENSG00000250264 Gene

  • XXbac-BPG246D15.9 5

External Ids for ENSG00000250264 Gene

Previous GeneCards Identifiers for ENSG00000250264 Gene

  • GC06M032784

Summaries for ENSG00000250264 Gene

GeneCards Summary for ENSG00000250264 Gene

ENSG00000250264 is a Protein Coding gene. GO annotations related to this gene include ATPase activity and MHC protein binding. An important paralog of this gene is TAP2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ENSG00000250264 Gene

Genomics for ENSG00000250264 Gene

Regulatory Elements for ENSG00000250264 Gene

Enhancers for ENSG00000250264 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06F032940 1.4 FANTOM5 ENCODE 11.6 -105.4 -105375 8.8 HDGF ATF1 WRNIP1 SIN3A ARID4B BRCA1 ZNF2 YY1 ZNF143 ZNF207 HLA-DMA BRD2 PSMB9 TAP1 TAP2 HLA-DMB BRD2-IT1 HLA-DPA1 ENSG00000250264 MIR6873
GH06F032983 0.4 ENCODE 11.1 -143.7 -143737 0.2 KLF1 BMI1 FEZF1 BCL11B POLR2A SCRT2 KLF8 SCRT1 CBFB CEBPB HLA-DMB ENSG00000250264 TAP2 TAP1 PSMB9 RNY4P10 RXRB SLC39A7 HSD17B8 MIR219A1
GH06F032950 0.2 ENCODE 11.1 -111.3 -111337 0.2 SCRT1 SCRT2 SPI1 TAP1 PSMB9 ENSG00000250264 TAP2 HLA-DRB1 ENSG00000248993 HLA-DMB
GH06F032982 0.5 Ensembl ENCODE 11.1 -145.4 -145366 2.7 HDGF PKNOX1 ATF1 ARID4B SIN3A FEZF1 ZNF2 SLC30A9 GLIS2 ZNF143 HLA-DMA HLA-DMB ENSG00000250264 TAP2 TAP1 PSMB9 RNY4P10 RXRB SLC39A7 HSD17B8
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ENSG00000250264 on UCSC Golden Path with GeneCards custom track

Promoters for ENSG00000250264 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000025363 322 1401 PKNOX1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF207 ZNF143

Genomic Location for ENSG00000250264 Gene

Chromosome:
6
Start:
32,813,767 bp from pter
End:
32,838,822 bp from pter
Size:
25,056 bases
Orientation:
Minus strand

Genomic View for ENSG00000250264 Gene

Genes around ENSG00000250264 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ENSG00000250264 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ENSG00000250264 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for ENSG00000250264 Gene

Proteins for ENSG00000250264 Gene

  • Protein details for ENSG00000250264 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    E7ENX8
    Recommended name:
    Uncharacterized protein
    Protein Accession:
    E7ENX8

    Protein attributes for ENSG00000250264 Gene

    Size:
    843 amino acids
    Molecular mass:
    92999 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ENSG00000250264 Gene

Post-translational modifications for ENSG00000250264 Gene

No Post-translational modifications

Other Protein References for ENSG00000250264 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for ENSG00000250264 Gene

Domains & Families for ENSG00000250264 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ENSG00000250264: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ENSG00000250264 Gene

Function for ENSG00000250264 Gene

Gene Ontology (GO) - Molecular Function for ENSG00000250264 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005524 ATP binding IEA --
GO:0015197 peptide transporter activity IEA --
GO:0015440 peptide-transporting ATPase activity IEA --
GO:0016887 ATPase activity IEA --
GO:0042287 MHC protein binding IEA --
genes like me logo Genes that share ontologies with ENSG00000250264: view

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ENSG00000250264 Gene

Localization for ENSG00000250264 Gene

Gene Ontology (GO) - Cellular Components for ENSG00000250264 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IBA --
GO:0030176 integral component of endoplasmic reticulum membrane IEA --
GO:0042613 MHC class II protein complex IEA --
GO:0042825 TAP complex IEA --
genes like me logo Genes that share ontologies with ENSG00000250264: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for ENSG00000250264 Gene

Pathways & Interactions for ENSG00000250264 Gene

SuperPathways for ENSG00000250264 Gene

No Data Available

Interacting Proteins for ENSG00000250264 Gene

Gene Ontology (GO) - Biological Process for ENSG00000250264 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002376 immune system process IEA --
GO:0002481 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent IBA --
GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent IBA --
GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent IBA --
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II IEA --
genes like me logo Genes that share ontologies with ENSG00000250264: view

No data available for Pathways by source and SIGNOR curated interactions for ENSG00000250264 Gene

Transcripts for ENSG00000250264 Gene

mRNA/cDNA for ENSG00000250264 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ENSG00000250264 Gene

No ASD Table

Relevant External Links for ENSG00000250264 Gene

GeneLoc Exon Structure for
ENSG00000250264

Expression for ENSG00000250264 Gene

mRNA expression in normal human tissues for ENSG00000250264 Gene

mRNA expression in normal human tissues for ENSG00000250264 Gene
genes like me logo Genes that share expression patterns with ENSG00000250264: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ENSG00000250264 Gene

Orthologs for ENSG00000250264 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ENSG00000250264 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 95 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 75 (a)
ManyToMany
TAP2 35
  • 71 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia TAP2 35
  • 75 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Tap2 35
  • 74 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 68 (a)
ManyToMany
-- 35
  • 64 (a)
ManyToMany
-- 35
  • 63 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 57 (a)
OneToMany
chicken
(Gallus gallus)
Aves TAP2 35
  • 49 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 53 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii abcb3l1 35
  • 41 (a)
ManyToMany
si:dkey-57h18.2 35
  • 37 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea haf-2 35
  • 30 (a)
ManyToMany
haf-9 35
  • 30 (a)
ManyToMany
haf-8 35
  • 29 (a)
ManyToMany
haf-4 35
  • 28 (a)
ManyToMany
haf-7 35
  • 25 (a)
ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes MDL1 35
  • 25 (a)
ManyToMany
MDL2 35
  • 25 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 31 (a)
ManyToMany
CSA.2338 35
  • 30 (a)
ManyToMany
Species where no ortholog for ENSG00000250264 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ENSG00000250264 Gene

ENSEMBL:
Gene Tree for ENSG00000250264 (if available)
TreeFam:
Gene Tree for ENSG00000250264 (if available)

Paralogs for ENSG00000250264 Gene

Paralogs for ENSG00000250264 Gene

genes like me logo Genes that share paralogs with ENSG00000250264: view

Variants for ENSG00000250264 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for ENSG00000250264 Gene

Disorders for ENSG00000250264 Gene

No disorders were found for ENSG00000250264 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for ENSG00000250264 Gene

Publications for ENSG00000250264 Gene

No publications were found for ENSG00000250264 Gene.

Products for ENSG00000250264 Gene

Sources for ENSG00000250264 Gene

Content
Loading form....