Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



ENSG00000230279 Gene

protein-coding   GIFtS: 14
GCID: GC06Po31529          (predicted)

ENSG00000230279


  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
LT-alpha3
TNF-beta3
TNFB3
TNFSF13
Tumor Necrosis Factor Ligand Superfamily Member 13

External Ids:    Ensembl: ENSG000002302797   UniProtKB: P013743   

Export aliases for ENSG00000230279 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for ENSG00000230279 Gene:
ENSG00000230279 is a protein-coding gene. Diseases associated with ENSG00000230279 include psoriatic arthritis.

UniProtKB/Swiss-Prot: TNFB_HUMAN, P01374
Function: Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its
heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a
wide range of tumor cells in vitro and in vivo




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
Regulatory elements:
   Search for regulatory transcription factor binding sites for ENSG00000230279
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for ENSG00000230279

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ENSG00000230279


Genomic Location:
Chromosome:6   

Ensembl cytogenetic band:  HSCHR6_MHC_SSTOp21.33   

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06Po31529:       (about GC identifiers)

Start:
31,529,774 bp from start of contig ALT_REF_LOCI_7      End:
31,532,044 bp from start of contig ALT_REF_LOCI_7
Size:
2,271 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: TNFB_HUMAN, P01374 (See protein sequence)
Recommended Name: Lymphotoxin-alpha precursor  
Size: 205 amino acids; 22297 Da
Subunit: Homotrimer, and heterotrimer of either two LTB and one LTA subunits or (less prevalent) two LTA and one
LTB subunits
3 PDB 3D structures from and Proteopedia for ENSG00000230279:
1TNR (3D)        4MXV (3D)        4MXW (3D)    
Secondary accessions: Q8N4C3 Q9UKS8

Explore the universe of human proteins at neXtProt for ENSG00000230279: NX_P01374


ENSEMBL proteins: 
 ENSP00000402413   ENSP00000412555   ENSP00000449673  

ENSG00000230279 Human Recombinant Protein Products:

Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
Browse OriGene Protein Over-expression Lysates
OriGene Custom MassSpec
OriGene Custom Protein Services for ENSG00000230279
GenScript Custom Purified and Recombinant Proteins Services for ENSG00000230279
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates
Browse ProSpec Recombinant Proteins
Browse Proteins at Cloud-Clone Corp.

 
Search eBioscience for Proteins for ENSG00000230279 

ENSG00000230279 Antibody Products:

EMD Millipore Mono- and Polyclonal Antibodies for the study of ENSG00000230279
Browse R&D Systems for Antibodies
Browse OriGene Antibodies
OriGene Custom Antibody Services for ENSG00000230279
Search for Antibodies for ENSG00000230279 at Abcam
Browse Antibodies at Cloud-Clone Corp.
Search ThermoFisher Antibodies for ENSG00000230279
Search LSBio for Antibodies for ENSG00000230279

ENSG00000230279 Assay Products:

Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for ENSG00000230279
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for ENSG00000230279
Browse Enzo Life Sciences for kits & assays
Browse ELISAs at Cloud-Clone Corp.
Browse CLIAs at Cloud-Clone Corp.
Search eBioscience for ELISAs for ENSG00000230279 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TryGeneCards Plus
5 InterPro protein domains:
 IPR006052 TNF_dom
 IPR002960 TNF_beta
 IPR006053 TNF
 IPR008983 Tumour_necrosis_fac-like_dom
 IPR021184 TNF_CS

Graphical View of Domain Structure for InterPro Entry P01374

ProtoNet protein and cluster: P01374

3 Blocks protein domains:
IPB002960 Tumour necrosis factor beta (lymphotoxin-alpha) signature
IPB006052 Tumor Necrosis Factor
IPB006053 Tumour necrosis factor family signature


UniProtKB/Swiss-Prot: TNFB_HUMAN, P01374
Similarity: Belongs to the tumor necrosis factor family


Find genes that share domains with ENSG00000230279           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Molecular Function:

     UniProtKB/Swiss-Prot Summary: TNFB_HUMAN, P01374
Function: Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its
heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a
wide range of tumor cells in vitro and in vivo

     Gene Ontology (GO): 4 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005102receptor binding ----
GO:0005125cytokine activity ----
GO:0005164tumor necrosis factor receptor binding ----
GO:0005515protein binding ----
     
Find genes that share ontologies with ENSG00000230279           About GenesLikeMe


Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ENSG00000230279
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ENSG00000230279

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ENSG00000230279
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ENSG00000230279

miRNA
Products:
    
Block miRNA regulation of human, mouse, rat ENSG00000230279 using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate ENSG00000230279
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
    
Browse OriGene RNAi
Predesigned siRNA for gene silencing in human, mouse, rat ENSG00000230279

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for ENSG00000230279

Clone
Products:
     
Browse OriGene untagged/tagged cDNA clones in CMV expression vector
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for ENSG00000230279
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for ENSG00000230279
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ENSG00000230279

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for ENSG00000230279
Browse ESI BIO Cell Lines and PureStem Progenitors for ENSG00000230279 
In Situ Assay
Products:
   

 
Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for ENSG00000230279


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Subcellular locations from UniProtKB/Swiss-Prot
TNFB_HUMAN, P01374: Secreted. Membrane. Note=The homotrimer is secreted. The heterotrimer is membrane-associated

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005615extracellular space ----
GO:0016020membrane ----

Find genes that share ontologies with ENSG00000230279           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
About This Section

TryGeneCards Plus



    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ENSG00000230279
Interactions:

    Search GeneGlobe Interaction Network for ENSG00000230279

Selected Interacting proteins for ENSG00000230279 (P013742, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
InteractantInteraction Details
GeneCardExternal ID(s)
LGALS2P051622, 3MINT-49838 MINT-49837 MINT-49836 I2D: score=4 
TUBA1AQ71U362, 3MINT-49840 I2D: score=1 
ENSG00000204487Q066433I2D: score=4 
ENSG00000206437Q066433I2D: score=4 
ENSG00000223448Q066433I2D: score=4 
About this table

Gene Ontology (GO): Selected biological process terms (see all 17):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0001666response to hypoxia ----
GO:0002876positive regulation of chronic inflammatory response to antigenic stimulus ----
GO:0002925positive regulation of humoral immune response mediated by circulating immunoglobulin ----
GO:0006915apoptotic process ----
GO:0006955immune response ----

Find genes that share ontologies with ENSG00000230279           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
About This Section

TryGeneCards Plus
Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for ENSG00000230279 (TNFB)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
About This Section

TryGeneCards Plus

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000426845(uc011jjr.1) ENST00000464086(uc011jjt.2 uc011jju.2 uc011jjv.2 uc011jjw.2)
ENST00000412851(uc011jjs.1) ENST00000473355 ENST00000550792
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat ENSG00000230279 using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate ENSG00000230279
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
Browse OriGene RNAi
Predesigned siRNA for gene silencing in human, mouse, rat ENSG00000230279
Clone
Products:
     
Browse OriGene untagged/tagged cDNA clones in CMV expression vector
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for ENSG00000230279
DNA2.0 Custom Codon Optimized Gene Synthesis Service for ENSG00000230279
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ENSG00000230279
Primer
Products:
    
Browse OriGene qPCR
Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat ENSG00000230279
  QuantiTect SYBR Green Assays in human, mouse, rat ENSG00000230279
  QuantiFast Probe-based Assays in human, mouse, rat ENSG00000230279

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TryGeneCards Plus
See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --

ENSG00000230279 Protein expression data from MOPED1, PaxDb2 and MaxQB3 --
    Custom PCR Arrays for ENSG00000230279
Primer
Products:
Browse OriGene qPCR
Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat ENSG00000230279
QuantiTect SYBR Green Assays in human, mouse, rat ENSG00000230279
QuantiFast Probe-based Assays in human, mouse, rat ENSG00000230279
In Situ
Assay Products:
 

 
Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for ENSG00000230279

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

TryGeneCards Plus
  --

ENSEMBL Gene Tree for ENSG00000230279 (if available)
TreeFam Gene Tree for ENSG00000230279 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section

TryGeneCards Plus
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

TryGeneCards Plus

Polymorphic Variants from UniProtKB/Swiss-Prot
TNFB_HUMAN, P01374: A polymorphism in LTA accounts, in part, for susceptibility to leprosy linked to chromosome 6p21.3
(LPRS4) [MIM:610988]

Site Specific Mutation Identification with PCR Assays
Search QIAGEN SeqTarget long-range PCR primers for resequencing ENSG00000230279
DNA2.0 Custom Variant and Variant Library Synthesis for ENSG00000230279

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TryGeneCards Plus
UniProtKB/Swiss-Prot: TNFB_HUMAN, P01374
  • Psoriatic arthritis (PSORAS) [MIM:607507]: An inflammatory, seronegative arthritis associated with
    psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive,
    erosive arthropathy. Five types of psoriatic arthritis have been defined: asymmetrical oligoarthritis
    characterized by primary involvement of the small joints of the fingers or toes; asymmetrical arthritis which
    involves the joints of the extremities; symmetrical polyarthritis characterized by a rheumatoid like pattern that
    can involve hands, wrists, ankles, and feet; arthritis mutilans, which is a rare but deforming and destructive
    condition; arthritis of the sacroiliac joints and spine (psoriatic spondylitis). Note=Disease susceptibility is
    associated with variations affecting the gene represented in this entry

  • 1 disease for ENSG00000230279:    
    About MalaCards
    psoriatic arthritis


    Find genes that share disorders with ENSG00000230279           About GenesLikeMe


    Export disorders for ENSG00000230279 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for ENSG00000230279 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with ENSG00000230279)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Stepwise replication identifies a low-producing lymphotoxin-alpha allele as a major risk factor for early-onset leprosy. (PubMed id 17353895)2 Alcaies A.... Abel L. (Nat. Genet. 2007)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. (PubMed id 14656967)2 Xie T.... Hood L. (Genome Res. 2003)
    4. Cytokine gene polymorphisms: association with psoriatic arthritis susceptibility and severity. (PubMed id 12746914)2 Balding J.... FitzGerald O. (Arthritis Rheum. 2003)
    5. A new member of the Ig superfamily and a V-ATPase G subunit are among the predicted products of novel genes close to the TNF locus in the human MHC. (PubMed id 10202016)2 Neville M.J. and Campbell R.D. (J. Immunol. 1999)
    6. Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation. (PubMed id 8387891)2 Banner D.W.... Lesslauer W. (Cell 1993)
    7. Dense Alu clustering and a potential new member of the NF kappa B family within a 90 kilobase HLA class III segment. (PubMed id 8499947)2 Iris F.J.M....Cohen D. (Nat. Genet. 1993)
    8. Nucleotide sequence of a cDNA encoding human tumor necrosis factor beta from B lymphoblastoid cell RPMI 1788. (PubMed id 1353024)2 Matsuyama N.... Kaji A. (FEBS Lett. 1992)
    9. Natural human tumor necrosis factor beta (lymphotoxin). Variable O- glycosylation at Thr7, proteolytic processing, and allelic variation. (PubMed id 1451807)2 Voigt C.G.... Adolf G.R. (FEBS Lett. 1992)
    10. The structure of human lymphotoxin (tumor necrosis factor-beta) at 1.9-A resolution. (PubMed id 1733919)2 Eck M.J.... Sprang S.R. (J. Biol. Chem. 1992)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Ensembl:ENSG00000230279

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    ATLAS Chromosomes in Cancer entry for ENSG00000230279 Genetics and Cytogenetics in Oncology and Haematology
    Wikipedia http://en.wikipedia.org/wiki/Lymphotoxin
    NIEHS-SNPshttp://egp.gs.washington.edu/data/lta/
    SeattleSNPshttp://pga.gs.washington.edu/data/lta/
    SHMPDhttp://shmpd.bii.a-star.edu.sg/gene.php?genestart=A&genename=LTA

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for ENSG00000230279 gene:
    Search GeneIP for patents involving ENSG00000230279

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     Browse Small Molecules at EMD Millipore
     EMD Millipore Mono- and Polyclonal Antibodies for the study of ENSG00000230279
     Browse Kits and Assays available from EMD Millipore
     Browse Purified and Recombinant Proteins at EMD Millipore
     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   Browse OriGene RNAi products  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   Browse OriGene clones  
     Browse OriGene qSTAR qPCR primer pairs   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ENSG00000230279   OriGene Custom Protein Services for ENSG00000230279  

     
     
     Block miRNA regulation of human, mouse, rat ENSG00000230279 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing ENSG00000230279
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ENSG00000230279 Predesigned siRNA for gene silencing in human, mouse, rat ENSG00000230279
     QuantiFast Probe-based Assays in human, mouse, rat ENSG00000230279 QuantiTect SYBR Green Assays in human, mouse, rat ENSG00000230279
     Custom PCR Arrays for ENSG00000230279 Search Chromatin IP Primers for ENSG00000230279
     Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat ENSG00000230279 Search GeneGlobe Interaction Network for ENSG00000230279
     Search Regulatory tfbs for ENSG00000230279
     GenScript Custom Purified and Recombinant Proteins Services for ENSG00000230279 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for ENSG00000230279
     GenScript Custom Assay Services for ENSG00000230279 GenScript Custom overexpressing Cell Line Services for ENSG00000230279
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for ENSG00000230279 (TNFB)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Biologicals
     Novus Tissue Slides
     Search for Antibodies for ENSG00000230279 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for ENSG00000230279
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for ENSG00000230279
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for ENSG00000230279
     Browse SwitchGear 3'UTR luciferase reporter plasmids for ENSG00000230279
     Browse SwitchGear Promoter luciferase reporter plasmids for ENSG00000230279
     Search ThermoFisher Antibodies for ENSG00000230279
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ENSG00000230279
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ENSG00000230279
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ENSG00000230279
     Search LSBio for Antibodies for ENSG00000230279
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for ENSG00000230279
      Search eBioscience for proteins for ENSG00000230279
      Search eBioscience for elisas for ENSG00000230279
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ENSG00000230279 gene at Home site.
    Version: 3.12.224 13 Oct 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4