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ENSG00000228284 Gene

protein-coding   GIFtS: 12
GCID: GC06Pm32632          (predicted)

ENSG00000228284


  Search for ENSG00000228284
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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External Ids:    Ensembl: ENSG000002282847   UniProtKB: Q67AE84   UniProtKB: Q67AB04   UniProtKB: Q67AF04   UniProtKB: Q67AB14   
UniProtKB: Q67AF44   UniProtKB: Q67AA44   UniProtKB: Q67AB24   UniProtKB: Q67AA24   UniProtKB: Q67AF54   
UniProtKB: Q67AB34   UniProtKB: Q9UEF54   UniProtKB: Q67AA84   UniProtKB: Q67AF24   UniProtKB: Q67AA34   
UniProtKB: Q67AE94   UniProtKB: Q67AF34   UniProtKB: Q67AF14   UniProtKB: Q5Y7H04   UniProtKB: Q9UM304   

Export aliases for ENSG00000228284 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ENSG00000228284 Gene:
ENSG00000228284 is a protein-coding gene.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Search for regulatory transcription factor binding sites for ENSG00000228284
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for ENSG00000228284

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ENSG00000228284


Genomic Location:
Chromosome:6   

Ensembl cytogenetic band:  HSCHR6_MHC_MCFp21.32   

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06Pm32632:       (about GC identifiers)

Start:
32,631,439 bp from start of contig ALT_REF_LOCI_5      End:
32,652,184 bp from start of contig ALT_REF_LOCI_5
Size:
20,746 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/TrEMBL: Q67AE8 (See protein sequence)
Recommended Name: MHC class II antigen  
Size: 227 amino acids; 25393 Da

UniProtKB/TrEMBL: Q67AB0 (See protein sequence)

Recommended Name: MHC class II antigen  
Size: 27 amino acids; 2762 Da

UniProtKB/TrEMBL: Q67AF0 (See protein sequence)

Recommended Name: MHC class II antigen  
Size: 227 amino acids; 25393 Da

UniProtKB/TrEMBL: Q67AB1 (See protein sequence)

Recommended Name: MHC class II antigen  
Size: 27 amino acids; 2762 Da

UniProtKB/TrEMBL: Q67AF4 (See protein sequence)

Recommended Name: MHC class II antigen  
Size: 227 amino acids; 25393 Da

UniProtKB/TrEMBL: Q67AA4 (See protein sequence)

Recommended Name: MHC class II antigen  
Size: 27 amino acids; 2762 Da

UniProtKB/TrEMBL: Q67AB2 (See protein sequence)

Recommended Name: MHC class II antigen  
Size: 27 amino acids; 2762 Da

UniProtKB/TrEMBL: Q67AA2 (See protein sequence)

Recommended Name: MHC class II antigen  
Size: 27 amino acids; 2762 Da

UniProtKB/TrEMBL: Q67AF5 (See protein sequence)

Recommended Name: MHC class II antigen  
Size: 227 amino acids; 25393 Da

UniProtKB/TrEMBL: Q67AB3 (See protein sequence)

Recommended Name: MHC class II antigen  
Size: 27 amino acids; 2762 Da

UniProtKB/TrEMBL: Q9UEF5 (See protein sequence)

Recommended Name: HMC class II surface glycoprotein  
Size: 27 amino acids; 2762 Da

UniProtKB/TrEMBL: Q67AA8 (See protein sequence)

Recommended Name: MHC class II antigen  
Size: 27 amino acids; 2762 Da

UniProtKB/TrEMBL: Q67AF2 (See protein sequence)

Recommended Name: MHC class II antigen  
Size: 227 amino acids; 25393 Da

UniProtKB/TrEMBL: Q67AA3 (See protein sequence)

Recommended Name: MHC class II antigen  
Size: 27 amino acids; 2762 Da

UniProtKB/TrEMBL: Q67AE9 (See protein sequence)

Recommended Name: MHC class II antigen  
Size: 227 amino acids; 25393 Da

UniProtKB/TrEMBL: Q67AF3 (See protein sequence)

Recommended Name: MHC class II antigen  
Size: 227 amino acids; 25393 Da

UniProtKB/TrEMBL: Q67AF1 (See protein sequence)

Recommended Name: MHC class II antigen  
Size: 227 amino acids; 25393 Da

UniProtKB/TrEMBL: Q5Y7H0 (See protein sequence)

Recommended Name: MHC class II antigen  
Size: 255 amino acids; 28208 Da

UniProtKB/TrEMBL: Q9UM30 (See protein sequence)

Recommended Name: Cell surface glycoprotein  
Size: 82 amino acids; 9583 Da

Explore proteomics data for ENSG00000228284 at MOPED


See ENSG00000228284 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB


ENSEMBL proteins: 
 ENSP00000413815   ENSP00000392580   ENSP00000399068   ENSP00000404172   ENSP00000414360  
 ENSP00000436724  

ENSG00000228284 Human Recombinant Protein Products:

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Search eBioscience for ELISAs for ENSG00000228284 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Selected InterPro protein domains (see all 7):
 IPR007110 Ig-like_dom
 IPR001003 MHC_II_a_N
 IPR003006 Ig/MHC_CS
 IPR011162 MHC_I/II-like_Ag-recog
 IPR013783 Ig-like_fold

Graphical View of Domain Structure for InterPro Entry Q67AE8
Graphical View of Domain Structure for InterPro Entry Q67AB0
Graphical View of Domain Structure for InterPro Entry Q67AF0
Graphical View of Domain Structure for InterPro Entry Q67AB1
Graphical View of Domain Structure for InterPro Entry Q67AF4
Graphical View of Domain Structure for InterPro Entry Q67AA4
Graphical View of Domain Structure for InterPro Entry Q67AB2
Graphical View of Domain Structure for InterPro Entry Q67AA2
Graphical View of Domain Structure for InterPro Entry Q67AF5
Graphical View of Domain Structure for InterPro Entry Q67AB3
Graphical View of Domain Structure for InterPro Entry Q9UEF5
Graphical View of Domain Structure for InterPro Entry Q67AA8
Graphical View of Domain Structure for InterPro Entry Q67AF2
Graphical View of Domain Structure for InterPro Entry Q67AA3
Graphical View of Domain Structure for InterPro Entry Q67AE9
Graphical View of Domain Structure for InterPro Entry Q67AF3
Graphical View of Domain Structure for InterPro Entry Q67AF1
Graphical View of Domain Structure for InterPro Entry Q5Y7H0
Graphical View of Domain Structure for InterPro Entry Q9UM30

ProtoNet protein and cluster: Q67AE8

2 Blocks protein domains:
IPB001003 MHC Class II alpha chain
IPB003597 Immunoglobulin C-type


UniProtKB/TrEMBL: Q67AE8
Similarity: Belongs to the MHC class II family
Similarity: Contains Ig-like C1-type (immunoglobulin-like) domain

UniProtKB/TrEMBL: Q67AF0
Similarity: Belongs to the MHC class II family
Similarity: Contains Ig-like C1-type (immunoglobulin-like) domain

UniProtKB/TrEMBL: Q67AF4
Similarity: Belongs to the MHC class II family
Similarity: Contains Ig-like C1-type (immunoglobulin-like) domain

UniProtKB/TrEMBL: Q67AF5
Similarity: Belongs to the MHC class II family
Similarity: Contains Ig-like C1-type (immunoglobulin-like) domain

UniProtKB/TrEMBL: Q67AF2
Similarity: Belongs to the MHC class II family
Similarity: Contains Ig-like C1-type (immunoglobulin-like) domain

UniProtKB/TrEMBL: Q67AE9
Similarity: Belongs to the MHC class II family
Similarity: Contains Ig-like C1-type (immunoglobulin-like) domain

UniProtKB/TrEMBL: Q67AF3
Similarity: Belongs to the MHC class II family
Similarity: Contains Ig-like C1-type (immunoglobulin-like) domain

UniProtKB/TrEMBL: Q67AF1
Similarity: Belongs to the MHC class II family
Similarity: Contains Ig-like C1-type (immunoglobulin-like) domain

UniProtKB/TrEMBL: Q5Y7H0
Similarity: Belongs to the MHC class II family
Similarity: Contains Ig-like C1-type (immunoglobulin-like) domain


Find genes that share domains with ENSG00000228284           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005515protein binding ----
     
Find genes that share ontologies with ENSG00000228284           About GenesLikeMe


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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0016020membrane ----
GO:0042613MHC class II protein complex ----

Find genes that share ontologies with ENSG00000228284           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ENSG00000228284
Interactions:

    Search GeneGlobe Interaction Network for ENSG00000228284

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for ENSG00000228284 (ENSP000004143604) via UniProtKB, MINT, STRING, and/or I2D (see all 32)
InteractantInteraction Details
GeneCardExternal ID(s)
ENSG00000230726ENSP000004029514STRING: ENSP00000402951
ENSG00000233209ENSP000003820254STRING: ENSP00000382025
ADAMTSL4-AS1ENSP000003580314STRING: ENSP00000358031
ATPIF1ENSP000003352034STRING: ENSP00000335203
C1orf105ENSP000003567004STRING: ENSP00000356700
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Gene Ontology (GO): 2 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006955immune response ----
GO:0019882antigen processing and presentation ----

Find genes that share ontologies with ENSG00000228284           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for ENSG00000228284



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000445944 ENST00000456258(uc011hzr.1 uc011hzs.1) ENST00000450614
ENST00000486605 ENST00000441297(uc011hzt.2) ENST00000463379 ENST00000420385
ENST00000484643 ENST00000474698 ENST00000481936
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GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --

ENSG00000228284 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

ENSG00000228284 Protein Expression
    Custom PCR Arrays for ENSG00000228284
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In Situ
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(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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  --

ENSEMBL Gene Tree for ENSG00000228284 (if available)
TreeFam Gene Tree for ENSG00000228284 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Site Specific Mutation Identification with PCR Assays
Search QIAGEN SeqTarget long-range PCR primers for resequencing ENSG00000228284
DNA2.0 Custom Variant and Variant Library Synthesis for ENSG00000228284

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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  --

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Ensembl:ENSG00000228284

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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  --

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for ENSG00000228284 gene:
Search GeneIP for patents involving ENSG00000228284

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 Search ThermoFisher Antibodies for ENSG00000228284
 Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ENSG00000228284
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ENSG00000228284
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