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Aliases for ENSG00000220986 Gene

Subcategory (RNA class) for ENSG00000220986 Gene

snoRNA

Quality Score for this RNA gene is

3

Aliases for ENSG00000220986 Gene

  • Small Nucleolar RNA SNORA50 5
  • SNORA50 5

External Ids for ENSG00000220986 Gene

ORGUL Members for ENSG00000220986 Gene

Previous GeneCards Identifiers for ENSG00000220986 Gene

  • GC05P068492
  • GC05P068456

Summaries for ENSG00000220986 Gene

GeneCards Summary for ENSG00000220986 Gene

ENSG00000220986 is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for ENSG00000220986 Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA76: ACA62 (SNORA76) is a member of the H/ACA class of snoRNAs that guide the sites of modification of uridines to pseudouridines [1]. This snoRNA was identified by computational screening and its expression in mouse experimentally verified by Northern blot and primer extension analysis [2]. ACA62 is proposed to guide the pseudouridylation of 18S rRNA U34 and U105 [2].

  • Small nucleolar RNA SNORA50: ACA50 is a member of the H/ACA class of snoRNA that guide the sites of modification of uridines to pseudouridines [1].

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for ENSG00000220986 Gene

Genomics for ENSG00000220986 Gene

Regulatory Elements for ENSG00000220986 Gene

Enhancers for ENSG00000220986 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05G069188 1.1 ENCODE 12.1 +28.9 28919 2.4 PKNOX1 CREB3L1 ARNT ARID4B SIN3A FEZF1 DMAP1 YY1 SLC30A9 ZNF143 CDK7 CCDC125 CCNB1 ENSG00000220986 MARVELD2 PIR48224 MRPS36
GH05G069093 1.1 ENCODE 11.8 -66.4 -66363 2.4 HDGF PKNOX1 CREB3L1 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ENSG00000220986 CCNB1 CENPH SLC30A5 OCLN SMN2 ENSG00000248664
GH05G069105 1 Ensembl ENCODE 12.1 -54.3 -54345 1.4 HDGF ARNT ZIC2 FOSL1 POLR2A ADNP SMARCE1 ZNF362 NR2F1 JUNB ENSG00000220986 CCNB1 CENPH CDK7 SMN2 OCLN SLC30A5 ENSG00000248664
GH05G069233 1.1 ENCODE 10.6 +74.1 74111 2.2 HDGF PKNOX1 CREB3L1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 CCDC125 CDK7 CENPH CCNB1 ENSG00000220986 CDH12P2 GC05P069259 GC05P069260
GH05G069129 0.9 ENCODE 11.3 -31.2 -31238 0.2 PKNOX1 NFRKB ZNF133 ZNF766 GATA2 ZNF366 ETV6 FOS IKZF2 CREM ENSG00000220986 CCNB1 CENPH ENSG00000248664 SLC30A5
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ENSG00000220986 on UCSC Golden Path with GeneCards custom track

Genomic Location for ENSG00000220986 Gene

Chromosome:
5
Start:
69,160,806 bp from pter
End:
69,160,939 bp from pter
Size:
134 bases
Orientation:
Plus strand

Genomic View for ENSG00000220986 Gene

Genes around ENSG00000220986 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ENSG00000220986 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ENSG00000220986 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

ORGUL Member Location for ENSG00000220986 Gene

ORGUL Member Location for ENSG00000220986 gene

No data available for RefSeq DNA sequence for ENSG00000220986 Gene

Proteins for ENSG00000220986 Gene

Post-translational modifications for ENSG00000220986 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ENSG00000220986 Gene

Domains & Families for ENSG00000220986 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ENSG00000220986 Gene

Function for ENSG00000220986 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ENSG00000220986 Gene

Localization for ENSG00000220986 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ENSG00000220986 Gene

Pathways & Interactions for ENSG00000220986 Gene

SuperPathways for ENSG00000220986 Gene

No Data Available

Interacting Proteins for ENSG00000220986 Gene

Gene Ontology (GO) - Biological Process for ENSG00000220986 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ENSG00000220986 Gene

Drugs & Compounds for ENSG00000220986 Gene

No Compound Related Data Available

Transcripts for ENSG00000220986 Gene

mRNA/cDNA for ENSG00000220986 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ENSG00000220986 Gene

No ASD Table

Relevant External Links for ENSG00000220986 Gene

GeneLoc Exon Structure for
ENSG00000220986

Expression for ENSG00000220986 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ENSG00000220986 Gene

genes like me logo Genes that share expression patterns with ENSG00000220986: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ENSG00000220986 Gene

Orthologs for ENSG00000220986 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ENSG00000220986 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia SNORA50 35
  • 81 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia SNORA50 35
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm23786 35
  • 69 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNORA50 35
  • 57 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA50 35
  • 42 (a)
OneToOne
chicken
(Gallus gallus)
Aves SNORA50 35
  • 58 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SNORA50 35
  • 54 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii SNORA50 35
  • 56 (a)
OneToOne
Species where no ortholog for ENSG00000220986 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ENSG00000220986 Gene

ENSEMBL:
Gene Tree for ENSG00000220986 (if available)
TreeFam:
Gene Tree for ENSG00000220986 (if available)

Paralogs for ENSG00000220986 Gene

No data available for Paralogs for ENSG00000220986 Gene

Variants for ENSG00000220986 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for ENSG00000220986 Gene

Disorders for ENSG00000220986 Gene

No disorders were found for ENSG00000220986 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for ENSG00000220986 Gene

Publications for ENSG00000220986 Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 1
  2. A computational screen for mammalian pseudouridylation guide H/ACA RNAs. (PMID: 16373490) Schattner P. … Lowe T.M. (RNA 2006) 1
  3. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss A.M. … Kiss T. (Mol. Cell. Biol. 2004) 1

Products for ENSG00000220986 Gene

Sources for ENSG00000220986 Gene

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