ENSG00000174093 Gene
protein-coding GIFtS: 16
GCID: GC17M036341 (predicted)
|
|
ENSG00000174093
| |
Aliases
for ENSG00000174093 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 1
| External Ids: | Ensembl: ENSG000001740937 | UniProtKB: E7EWZ24 | UniProtKB: F5GZY44 | UniProtKB: E5RJ244 | | ORGUL members: | |
|---|
| NONCODE:n383172 | |
Export aliases for ENSG00000174093 gene to outside databasesPrevious GC identifers: GC17P035972 GC17M036997 GC17M036734 GC17M033605 GC17M036351
|---|
Summaries
for ENSG00000174093 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ENSG00000174093 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ENSG00000174093
Other transcription factors
Search SABiosciences Chromatin IP Primers for ENSG00000174093
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ENSG00000174093 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Ensembl cytogenetic band: 17q12 ENSG00000174093 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M036341: view genomic region
(about GC identifiers)
Start:
|
36,337,717 bp from pter |
End:
|
36,421,858 bp from pter |
Size:
|
84,142 bases |
Orientation:
|
minus strand |
|
Proteins
for ENSG00000174093 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/TrEMBL: E7EWZ2 (See
protein sequence)Recommended Name: TBC1 domain family member 3 Size: 478 amino acids; 53718 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered aspreliminary dataUniProtKB/TrEMBL: F5GZY4 (See
protein sequence) Recommended Name: TBC1 domain family member 3 Size: 324 amino acids; 36957 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered aspreliminary dataUniProtKB/TrEMBL: E5RJ24 (See
protein sequence) Recommended Name: TBC1 domain family member 3 Size: 471 amino acids; 53145 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered aspreliminary dataENSG00000174093 Protein expression data from MOPED and PaxDb: About this image 
ENSEMBL proteins: ENSP00000429970 ENSP00000428199 ENSP00000428560 ENSP00000428261 ENSP00000427867 ENSP00000428330 ENSP00000444117 ENSP00000308540
Human Recombinant Protein Products:
ENSG00000174093 Antibody Products:
Assay Products for ENSG00000174093: |
Protein
Domains /
Families
for ENSG00000174093 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ENSG00000174093 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry E7EWZ2Graphical View of Domain Structure for InterPro Entry F5GZY4Graphical View of Domain Structure for InterPro Entry E5RJ24ProtoNet protein and cluster: E7EWZ2 |
Function
for ENSG00000174093 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ENSG00000174093 for ontologies About GeneDecksing
|
Pathways & Interactions
for ENSG00000174093 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ENSG00000174093
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006508 | proteolysis |
-- | -- |
ENSG00000174093 for ontologies About GeneDecksing
|
Drugs & Compounds
for ENSG00000174093 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ENSG00000174093
Search CenterWatch for drugs/clinical trials and news about ENSG00000174093 
|
Transcripts
for ENSG00000174093 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
9 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000523258(uc002hpr.2 uc010cvk.2) ENST00000523052 ENST00000520499
ENST00000520237 ENST00000400815(uc002hpx.2) ENST00000523089 ENST00000518004
ENST00000544906(uc010wdn.1) ENST00000312412
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for ENSG00000174093 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 |
|---|
|
| SP1: | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
|
Expression
for ENSG00000174093 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ENSG00000174093 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See ENSG00000174093 Protein Expression from SPIRE MOPED and PaxDB SABiosciences Custom PCR Arrays for ENSG00000174093
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat ENSG00000174093 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ENSG00000174093 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ENSG00000174093 |
Orthologs
for ENSG00000174093 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ENSG00000174093 gene from 7/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
NPEPPS6 |
Uncharacterized protein |
45(a) |
1 → many |
27(3824329-3849587) |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
44(a) |
1 → many |
6(74116455-74177355) |
zebrafish
(Danio rerio) |
Actinopterygii |
npepps6 |
aminopeptidase puromycin sensitive |
41(a) |
1 → many |
11(12298986-12349043) |
fruit fly
(Drosophila melanogaster) |
Insecta |
Psa6 |
Puromycin sensitive aminopeptidase |
26(a) |
1 → many |
3L(1502843-1523380) |
worm
(Caenorhabditis elegans) |
Secernentea |
pam-16 |
Puromycin-sensitive AMinopeptidase family member (... |
20(a) |
1 → many |
IV(7543970-7550793) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
APM16 |
aminopeptidase M1 |
27(a) |
1 → many |
4(15965741-15970456) |
rice
(Oryza sativa) |
Liliopsida |
----(see all 4) |
aminopeptidase, putativepuromycin-sensitive aminopeptidase, putative, expr...(see all 4) |
43(a)26(a)(see all 4) |
many ↔ manymany ↔ many(see all 4) |
9(11852027-11856936) 8(19019102-19029143) |
ENSEMBL Gene Tree for ENSG00000174093 (if available)
TreeFam Gene Tree for ENSG00000174093 (if available) |
Paralogs
for ENSG00000174093 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ENSG00000174093 gene
- LNPEP2 ENPEP2 ANPEP2 TRHDE2 ERAP12 AQPEP2 NPEPPS2 ERAP22
ENSG00000174093 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for ENSG00000174093
PGOHUM00000257058
|
Genomic Variants
for ENSG00000174093 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for ENSG00000174093 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ENSG00000174093 for disorders About GeneDecksing
4  diseases for ENSG00000174093: About MalaCardspneumonia tuberculosis neuronitis mycobacterium tuberculosis
Export disorders for ENSG00000174093 gene to outside databases
|
Publications
for ENSG00000174093 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
| -- |
External Searches for ENSG00000174093 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ENSG00000174093 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ENSG00000174093 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ENSG00000174093 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ENSG00000174093 gene:
Search GeneIP for patents involving ENSG00000174093
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ENSG00000174093 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 |
| | | | |
 |
 |
|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ENSG00000174093 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ENSG00000174093 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ENSG00000174093 | | | Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ENSG00000174093 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ENSG00000174093 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ENSG00000174093 |
| |
 |  |  |  | |
| | | |  |  |  |  | | | | |
 |
 |
 |
 | | | | |  |  |  | | | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ENSG00000174093 |
|
|
|
|
GeneCards Homepage -
Last full update: 19 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013
View Random Gene
|
Category
|
|
|
von Willebrand factor
|
| GIFtS Group |
|
Developed at the Crown Human Genome Center,
Department of Molecular Genetics,
the Weizmann Institute of Science
Copyright © 1996-2013
, Weizmann Institute of Science. All Rights Reserved.
hostname: 356980-web2.xennexinc.com
index build: 100 solr: 1.4
|
