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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ENSG00000096150 Gene

protein-coding   GIFtS: 18
GCID: GC06Pn33168          (predicted)

ENSG00000096150


  Search for ENSG00000096150
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
D6S218E3
Ke-33
Ke33

External Ids:    Ensembl: ENSG000000961507   UniProtKB: P622693   

Export aliases for ENSG00000096150 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ENSG00000096150 Gene: 
ENSG00000096150 is a protein-coding gene.

UniProtKB/Swiss-Prot: RS18_HUMAN, P62269
Function: Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for ENSG00000096150
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for ENSG00000096150

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ENSG00000096150


Genomic Location:
Chromosome:6   

Ensembl cytogenetic band:  HSCHR6_MHC_QBLp21.32   

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06Pn33168:       (about GC identifiers)

Start:
33,168,626 bp from pter      End:
33,173,129 bp from pter
Size:
4,504 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RS18_HUMAN, P62269 (See protein sequence)
Recommended Name: 40S ribosomal protein S18  
Size: 152 amino acids; 17719 Da
Subcellular location: Cytoplasm
1 PDB 3D structure from and Proteopedia for ENSG00000096150:
3J3A (3D)    
Secondary accessions: P25232 Q5SUJ3 Q6IPF8

Explore the universe of human proteins at neXtProt for ENSG00000096150: NX_P62269

Explore proteomics data for ENSG00000096150 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P62269

  • ENSG00000096150 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ENSG00000096150 Protein Expression

    ENSEMBL proteins: 
     ENSP00000211372   ENSP00000437050   ENSP00000431986  
    Reactome Protein details: P62269
    Human Recombinant Protein Products for ENSG00000096150: 
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    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005581collagen ----
    GO:0005622intracellular ----
    GO:0005829cytosol ----
    GO:0005840ribosome ----
    GO:0015935small ribosomal subunit ----

    ENSG00000096150 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR027437 30s_Rbsml_prot_S13_C
     IPR010979 Ribosomal_S13-like_H2TH
     IPR018269 Ribosomal_S13_CS
     IPR001892 Ribosomal_S13

    Graphical View of Domain Structure for InterPro Entry P62269

    ProtoNet protein and cluster: P62269

    UniProtKB/Swiss-Prot: RS18_HUMAN, P62269
    Similarity: Belongs to the ribosomal protein S13P family


    ENSG00000096150 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RS18_HUMAN, P62269
    Function: Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA (By
    similarity)

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ----
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding ----
    GO:0003735structural constituent of ribosome ----
    GO:0019843rRNA binding ----
         
    ENSG00000096150 for ontologies           About GeneDecksing


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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    Pathways by sourceSee SuperPaths
    Show all pathways


    5/27        Reactome Pathways for ENSG00000096150 (see all 27)
        Formation of the ternary complex, and subsequently, the 43S complex
    Nonsense Mediated Decay Independent of the Exon Junction Complex
    Nonsense-Mediated Decay
    Translation
    SRP-dependent cotranslational protein targeting to membrane



    ENSG00000096150 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ENSG00000096150

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/829 Interacting proteins for ENSG00000096150 (P622692, 3 ENSP000002113724) via UniProtKB, MINT, STRING, and/or I2D (see all 829)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPS3P233962, 3, ENSP000002785724MINT-7945693 I2D: score=4 STRING: ENSP00000278572
    KPNA2P522922, 3MINT-7945693 I2D: score=3 
    RPL8P629172, 3MINT-7945693 I2D: score=3 
    RPS17LP0CW222, 3MINT-8395092 I2D: score=3 
    RPS2P158802, 3MINT-6541718 I2D: score=3 
    About this table

    Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ----
    GO:0006412translation ----
    GO:0006413translational initiation ----
    GO:0006414translational elongation ----
    GO:0006415translational termination ----

    ENSG00000096150 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ENSG00000096150 (RS18)

    Search CenterWatch for drugs/clinical trials and news about ENSG00000096150 / RS18

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000211372(uc011jad.1) ENST00000477055 ENST00000481330 ENST00000476288(uc011jae.1)
    ENST00000464447 ENST00000470852 ENST00000489474 ENST00000477733
    miRNA
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    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ENSG00000096150    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b ^ 5
    SP1:                                                      
    SP2:                                -     -               
    SP3:        -     -                                       
    SP4:                                                      



    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section
    See probesets specificity/sensitivity at GeneAnnot
    CGAP TAG: --


    See ENSG00000096150 Protein Expression from SPIRE MOPED and PaxDB    SABiosciences Custom PCR Arrays for ENSG00000096150
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
      --

    ENSEMBL Gene Tree for ENSG00000096150 (if available)
    TreeFam Gene Tree for ENSG00000096150 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ENSG00000096150 gene

    ENSG00000096150 for paralogs           About GeneDecksing


    5/15 Pseudogenes.org Pseudogenes for ENSG00000096150 (see all 15)
    PGOHUM00000248253 PGOHUM00000236925 PGOHUM00000234539 PGOHUM00000245071 PGOHUM00000245228


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ENSG00000096150 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with ENSG00000096150)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    2. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (2009)
    3. Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    5. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)2 Mungall A.J.... Beck S. (2003)
    6. Characterization of the human small-ribosomal-subunit proteins by N- terminal and internal sequencing, and mass spectrometry. (PubMed id 8706699)2 Vladimirov S.N.... Otto A. (1996)
    7. The human homolog of ribosomal protein S18. (PubMed id 8441687)2 Chassin D.... Koman A. (1993)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Ensembl:ENSG00000096150

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
      --

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ENSG00000096150 gene:
    Search GeneIP for patents involving ENSG00000096150

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    About This Section

     
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     Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for ENSG00000096150
     Browse SwitchGear 3'UTR luciferase reporter plasmids for ENSG00000096150
     Browse SwitchGear Promoter luciferase reporter plasmids for ENSG00000096150
     Search ThermoFisher Antibodies for ENSG00000096150
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ENSG00000096150
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ENSG00000096150
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ENSG00000096150
    Customized:
     lentivirus for stable overexpression of ENSG00000096150
     lentivirus expression plasmids for stable overexpression of ENSG00000096150
     adenovirus for overexpression of ENSG00000096150
     Search LSBio for Antibodies for ENSG00000096150
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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