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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ENOPH1 Gene

protein-coding   GIFtS: 54
GCID: GC04P083351

enolase-phosphatase 1

 Explore 7 diseases affiliated with
ENOPH1 via our new
 Human Malady Compendium 
Biological research products
for ENOPH1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Enolase-Phosphatase 11 2     EC 3.1.3.773 8
MASA1 2 3     MST1452
E11 2     Acireductone Synthase2
2,3-Diketo-5-Methylthio-1-Phosphopentane Phosphatase2 3     Enolase-Phosphatase E12
MASA Homolog2 3     

External Ids:    HGNC: 245991   Entrez Gene: 584782   Ensembl: ENSG000001452937   UniProtKB: Q9UHY73   

Export aliases for ENOPH1 gene to outside databases

Previous GC identifers: GC04P083570 GC04P079093


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ENOPH_HUMAN, Q9UHY7
Function: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P)
into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then
dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.1  NT_016354.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ENOPH1 gene promoter:
         E2F-4   E2F-3a   HFH-3   E2F-1   E2F   E2F-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidENOPH1 promoter sequence
   Search SABiosciences Chromatin IP Primers for ENOPH1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ENOPH1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q21.22   Ensembl cytogenetic band:  4q21.22   HGNC cytogenetic band: 4q21.3

ENOPH1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ENOPH1 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P083351:  view genomic region     (about GC identifiers)

Start:
83,351,715 bp from pter      End:
83,382,244 bp from pter
Size:
30,530 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ENOPH_HUMAN, Q9UHY7 (See protein sequence)
Recommended Name: Enolase-phosphatase E1  
Size: 261 amino acids; 28933 Da
Cofactor: Binds 1 magnesium ion per subunit
Subunit: Monomer
Subcellular location: Cytoplasm (By similarity). Nucleus (By similarity)
Sequence caution: Sequence=AAQ13671.1; Type=Frameshift; Positions=235;
2 PDB 3D structures from and Proteopedia for ENOPH1:
1YNS (3D)        1ZS9 (3D)    
Secondary accessions: Q7Z4C5 Q9BVC2
Alternative splicing: 2 isoforms:  Q9UHY7-1   Q9UHY7-2   

Explore the universe of human proteins at neXtProt for ENOPH1: NX_Q9UHY7

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UHY7

  • 4/10 DME Specific Peptides for ENOPH1 (Q9UHY7) (see all 10)
     LLDIEGT  IGHKVES  NILFLTDV  SSGSVEAQ 

    ENOPH1 Protein expression data from MOPED and PaxDb:    About this image 
    ENOPH1 Protein Expression
    REFSEQ proteins: NP_067027.1  
    ENSEMBL proteins: 
     ENSP00000273920   ENSP00000422005   ENSP00000427209  
    Reactome Protein details: Q9UHY7
    Human Recombinant Protein Products for ENOPH1: 
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    Novus Biologicals ENOPH1 Lysates
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    ProSpec Recombinant Protein for ENOPH1
    Uscn Proteins for ENOPH1

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005634nucleus IEA--
    GO:0005829cytosol TAS--

    ENOPH1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ENOPH1 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR006439 HAD-SF_hydro_IA_v1
     IPR023214 HAD-like_dom
     IPR023943 Enolase-ppase_E1

    Graphical View of Domain Structure for InterPro Entry Q9UHY7

    ProtoNet protein and cluster: Q9UHY7

    UniProtKB/Swiss-Prot: ENOPH_HUMAN, Q9UHY7
    Similarity: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ENOPH_HUMAN, Q9UHY7
    Function: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P)
    into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then
    dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene)
    Catalytic activity: 5-(methylthio)-2,3-dioxopentyl phosphate + H(2)O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one +
    phosphate

         Enzyme Number (IUBMB): EC 3.1.3.771 2

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000287magnesium ion binding IEA--
    GO:0008967phosphoglycolate phosphatase activity IEA--
    GO:00437152,3-diketo-5-methylthiopentyl-1-phosphate enolase activity ----
    GO:00437162-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity ----
    GO:0043874acireductone synthase activity TAS--
         
    ENOPH1 for ontologies           About GeneDecksing


    Animal Models:
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ENOPH1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Methionine salvage pathway
    Methionine salvage pathway1.00
    Metabolism of polyamines0.40
    S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation0.67
    2Sulfur amino acid metabolism
    Sulfur amino acid metabolism1.00
    Cysteine and methionine metabolism0.36
    3Metabolism of amino acids and derivatives
    Metabolism of amino acids and derivatives1.00
    4Metabolism
    Metabolism1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for ENOPH1 
        S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation

    5        Reactome Pathways for ENOPH1
        Metabolism of polyamines
    Metabolism
    Methionine salvage pathway
    Sulfur amino acid metabolism
    Metabolism of amino acids and derivatives


    1         Kegg Pathway  (Kegg details for ENOPH1):
        Cysteine and methionine metabolism

    UniProtKB/Swiss-Prot: ENOPH_HUMAN, Q9UHY7
    Pathway: Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from
    S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 3/6
    Pathway: Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from
    S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 4/6


    ENOPH1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ENOPH1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/22 Interacting proteins for ENOPH1 (Q9UHY72, 3 ENSP000002739204) via UniProtKB, MINT, STRING, and/or I2D (see all 22)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPS27P426772, 3, ENSP000003575554MINT-8269318 I2D: score=4 STRING: ENSP00000357555
    RAB10P610262, 3, ENSP000002647104MINT-8267731 I2D: score=2 STRING: ENSP00000264710
    ADI1Q9BV573, ENSP000003336664I2D: score=1 STRING: ENSP00000333666
    APIPQ96GX93, ENSP000002783594I2D: score=1 STRING: ENSP00000278359
    VBP1P617583, ENSP000002864284I2D: score=1 STRING: ENSP00000286428
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000096sulfur amino acid metabolic process TAS--
    GO:0006595polyamine metabolic process TAS--
    GO:0019509L-methionine salvage from methylthioadenosine TAS--
    GO:0034641cellular nitrogen compound metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--

    ENOPH1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    ENOPH1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for ENOPH1

    3 HMDB Compounds for ENOPH1    About this table
    CompoundSynonyms CAS #PubMed Ids
    MagnesiumMagnesium (see all 2)7439-95-4--
    PhosphateNFB Orthophosphate (see all 13)14265-44-2--
    WaterDihydrogen oxide (see all 2)7732-18-5--

    1 DrugBank Compound for ENOPH1    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    2-OXOHEPTYLPHOSPHONIC ACID-- --target--10592235

    3 Novoseek chemical compound relationships for ENOPH1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cysteine 48.4 4 8321287 (1), 11890701 (1), 1515036 (1), 20164921 (1)
    pyruvate 25 3 8344439 (1), 9007715 (1)
    atp 15.8 3 1649632 (1), 20448897 (1)

    Search CenterWatch for drugs/clinical trials and news about ENOPH1 / ENOPH 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ENOPH1 gene: 
    NM_021204.3  

    Unigene Cluster for ENOPH1:

    Enolase-phosphatase 1
    Hs.18442  [show with all ESTs]
    Unigene Representative Sequence: NM_021204
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000273920(uc003hmv.3 uc003hmx.3) ENST00000509635 ENST00000505846


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    Additional cDNA sequence: 

    AF087881.1 AF113125.1 AF177286.1 AK022656.1 AL110167.1 BC001317.1 BC065815.1 CR457141.1 

    23 DOTS entries:

    DT.95215271  DT.99955049  DT.121220779  DT.75136185  DT.91759671  DT.100645207  DT.100815443  DT.121220876 
    DT.91759674  DT.100815445  DT.95215269  DT.95215272  DT.100815444  DT.121220687  DT.121220706  DT.121220710 
    DT.121220861  DT.121220899  DT.121220932  DT.91976208  DT.95148785  DT.97796737  DT.91746894 

    24/255 AceView cDNA sequences (see all 255):

    BU615698 AI263019 AL529358 BC001317 CR623426 AA360888 BQ053059 AI702502 
    AI248672 BM849398 CR615673 AA370221 AI382666 AI270773 AF177286 BF195902 
    AI985488 CD679581 AI695232 R18965 AA338858 AI204417 BC065815 BG499942 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for ENOPH1 (see all 10)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c · 9d ^ 10a · 10b · 10c · 10d · 10e
    SP1:              -     -     -     -     -     -     -                                         -                                                   
    SP2:                                      -     -     -                                         -                                                   
    SP3:                                -     -     -     -                 -                       -                                                   
    SP4:                                -     -     -     -                                         -                                                   
    SP5:                                                  -                                                                                             


    ECgene alternative splicing isoforms for ENOPH1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ENOPH1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTGTGATTAA
    ENOPH1 Expression
    About this image
    See ENOPH1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ENOPH1

    SOURCE GeneReport for Unigene cluster: Hs.18442
        SABiosciences Expression via Pathway-Focused PCR Array including ENOPH1: 

              Amino Acid Metabolism I in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ENOPH1 gene from 10/26 species (see all 26)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Enoph11 , 5 enolase-phosphatase 11, 5 85.34(n)1
    94.55(a)1
      5 (48.46 cM)5
    678701  NM_001163035.11  NP_001156507.11 
     1000399945 
    chicken
    (Gallus gallus)
    Aves ENOPH11 enolase-phosphatase 1 72.8(n)
    78.54(a)
      422600  XM_420559.3  XP_420559.3 
    lizard
    (Anolis carolinensis)
    Reptilia ENOPH16
    --
    72(a)
    1 ↔ 1
    5(42929817-42935950)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.135902 Xenopus laevis transcribed sequence with weak similarity more 73.83(n)    BX847718.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BI890272.12   -- 71.76(n)    BI890272.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG121731 CG12173 52.36(n)
    42.92(a)
      40630  NM_141266.2  NP_649523.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F58H1.31 Protein F58H1.3 51.4(n)
    44.96(a)
      179634  NM_001047673.1  NP_001041138.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes UTR4(YEL038W)4
    UTR41
    Protein with sequence similarity to 2,3-diketo-5-methylthiopentyl-1-phosphate more4
    Utr4p1
    48.57(n)1
    38.57(a)1
      5(80462-81145)4
    8566731, 4  NP_010876.21, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G538506
    Enolase-phosphatase E1
    23(a)
    1 ↔ 1
    5(21860997-21864973)
    rice
    (Oryza sativa)
    Liliopsida Os01g01012001 hypothetical protein 52.06(n)
    49.79(a)
      4326460  NM_001048276.1  NP_001041741.1 


    ENSEMBL Gene Tree for ENOPH1 (if available)
    TreeFam Gene Tree for ENOPH1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ENOPH1 gene

    ENOPH1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for ENOPH1
    PGOHUM00000237900


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/453 NCBI SNPs in ENOPH1 are shown (see all 453    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1412663301,2
    --83353475(+) AAGAAA/CTCGAG 1 -- int10--------
    rs1875370121,2
    --83353530(+) TCTCGC/TTCTGT 1 -- int10--------
    rs1927896031,2
    --83353616(+) TCGCAC/GCCTCT 1 -- int10--------
    rs1854337401,2
    --83353727(+) AAGTGA/GTTCAC 1 -- int10--------
    rs1890580831,2
    --83353863(+) GAATAC/TAGTGG 1 -- int10--------
    rs76731561,2
    C--83353944(+) cgcacA/Caccac 1 -- int10--------
    rs1483274501,2
    --83353958(+) CGGCTA/GATTTT 1 -- int10--------
    rs1919087651,2
    --83354045(+) GGCGCA/GAGCCA 1 -- int10--------
    rs1842958611,2
    --83354054(+) CACCGC/TGCCTG 1 -- int10--------
    rs1891157541,2
    --83354091(+) CAGAGA/GCCTCT 1 -- int10--------

    HapMap Linkage Disequilibrium report for ENOPH1 (83351715 - 83382244 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for ENOPH1
         2 CNVs: 92225 92224

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ENOPH1
    DNA2.0 Custom Variant and Variant Library Synthesis for ENOPH1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ENOPH1 for disorders           About GeneDecksing

    7 diseases for ENOPH1:    About MalaCards
    primary biliary cirrhosis    multiple myeloma    papilloma    parkinson's disease
    myeloma    retinoblastoma    leukemia


    Export disorders for ENOPH1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ENOPH1 gene, integrated from 9 sources (see all 61):
    (articles sorted by number of sources associating them with ENOPH1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Crystal structure of human E1 enzyme and its complex with a substrate analog reveals the mechanism of its phosphatase/enolase activity. (PubMed id 15843022)1, 2, 3, 9 Wang H.... Rao Z. (2005)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (2000)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    8. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. The Protein Data Bank. (PubMed id 10592235)7 Berman H.M....Bourne P.E. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 58478 HGNC: 24599 AceView: MASA Ensembl:ENSG00000145293 euGenes: HUgn58478
    ECgene: ENOPH1 Kegg: 58478 H-InvDB: ENOPH1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ENOPH1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ENOPH1 gene:
    Search GeneIP for patents involving ENOPH1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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