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Aliases for ENKD1 Gene

Aliases for ENKD1 Gene

  • Enkurin Domain Containing 1 2 3
  • C16orf48 3 4
  • Chromosome 16 Open Reading Frame 48 2
  • Enkurin Domain-Containing Protein 1 3
  • DAKV6410 3

External Ids for ENKD1 Gene

Previous Symbols for ENKD1 Gene

  • C16orf48

Summaries for ENKD1 Gene

GeneCards Summary for ENKD1 Gene

ENKD1 (Enkurin Domain Containing 1) is a Protein Coding gene.

Gene Wiki entry for ENKD1 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ENKD1 Gene

Genomics for ENKD1 Gene

Genomic Location for ENKD1 Gene

Start:
67,662,945 bp from pter
End:
67,667,265 bp from pter
Size:
4,321 bases
Orientation:
Minus strand

Genomic View for ENKD1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ENKD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ENKD1 Gene

No data available for Regulatory Elements for ENKD1 Gene

Proteins for ENKD1 Gene

  • Protein details for ENKD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H0I2-ENKD1_HUMAN
    Recommended name:
    Enkurin domain-containing protein 1
    Protein Accession:
    Q9H0I2
    Secondary Accessions:
    • Q6UWD7

    Protein attributes for ENKD1 Gene

    Size:
    346 amino acids
    Molecular mass:
    38759 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ENKD1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ENKD1 Gene

Proteomics data for ENKD1 Gene at MOPED

Post-translational modifications for ENKD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ENKD1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ENKD1 Gene

Domains for ENKD1 Gene

Protein Domains for ENKD1 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

ENKD1_HUMAN
Domain:
  • Contains 1 enkurin domain.:
    • Q9H0I2
genes like me logo Genes that share domains with ENKD1: view

No data available for Gene Families for ENKD1 Gene

Function for ENKD1 Gene

Gene Ontology (GO) - Molecular Function for ENKD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with ENKD1: view

Phenotypes for ENKD1 Gene

GenomeRNAi human phenotypes for ENKD1:
genes like me logo Genes that share phenotypes with ENKD1: view

miRNA for ENKD1 Gene

miRTarBase miRNAs that target ENKD1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ENKD1 Gene

Localization for ENKD1 Gene

Gene Ontology (GO) - Cellular Components for ENKD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005881 cytoplasmic microtubule IDA 23264731
GO:0015630 microtubule cytoskeleton IDA --
genes like me logo Genes that share ontologies with ENKD1: view

Pathways for ENKD1 Gene

SuperPathways for ENKD1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ENKD1 Gene

None

No data available for Pathways by source for ENKD1 Gene

Transcripts for ENKD1 Gene

mRNA/cDNA for ENKD1 Gene

Unigene Clusters for ENKD1 Gene

Enkurin domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ENKD1 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b · 9c
SP1: - - - -
SP2: - - - -
SP3: - -
SP4: - - -
SP5: - - -
SP6: - - - - - - -
SP7:

Relevant External Links for ENKD1 Gene

GeneLoc Exon Structure for
ENKD1
ECgene alternative splicing isoforms for
ENKD1

Expression for ENKD1 Gene

mRNA expression in normal human tissues for ENKD1 Gene

mRNA differential expression in normal tissues according to GTEx for ENKD1 Gene

This gene is overexpressed in Pancreas (4.8).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ENKD1 Gene

SOURCE GeneReport for Unigene cluster for ENKD1 Gene Hs.729159

genes like me logo Genes that share expressions with ENKD1: view

Orthologs for ENKD1 Gene

This gene was present in the common ancestor of animals.

Orthologs for ENKD1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ENKD1 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ENKD1 36
  • 87.54 (n)
  • 89.57 (a)
ENKD1 37
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ENKD1 36
  • 87.73 (n)
  • 88.99 (a)
ENKD1 37
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Enkd1 36
  • 83.86 (n)
  • 84.64 (a)
Enkd1 16
Enkd1 37
  • 84 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ENKD1 37
  • 55 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ENKD1 37
  • 58 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Enkd1 36
  • 84.64 (n)
  • 86.09 (a)
chicken
(Gallus gallus)
Aves C11H16ORF48 36
  • 65.41 (n)
  • 58.67 (a)
ENKD1 37
  • 53 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ENKD1 37
  • 53 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia enkd1 36
  • 55.23 (n)
  • 50.58 (a)
zebrafish
(Danio rerio)
Actinopterygii ENKD1 37
  • 49 (a)
OneToOne
si:ch211-220d9.3 36
  • 57.19 (n)
  • 53.89 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG11125 37
  • 19 (a)
OneToOne
Species with no ortholog for ENKD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ENKD1 Gene

ENSEMBL:
Gene Tree for ENKD1 (if available)
TreeFam:
Gene Tree for ENKD1 (if available)

Paralogs for ENKD1 Gene

No data available for Paralogs for ENKD1 Gene

Variants for ENKD1 Gene

Sequence variations from dbSNP and Humsavar for ENKD1 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs3833057 -- 67,663,886(+) CCCCC(-/C)ACACC intron-variant
rs5021812 -- 67,664,343(+) GGCTC(C/T)TAACA intron-variant
rs5021813 -- 67,664,269(+) TCCAC(C/T)TCAGT intron-variant
rs12103167 -- 67,663,335(+) GGCCC(A/G)GGAAC intron-variant
rs12599958 -- 67,663,737(+) AGGAC(C/G/T)TGCAG synonymous-codon, missense, reference

Relevant External Links for ENKD1 Gene

HapMap Linkage Disequilibrium report
ENKD1

No data available for Structural Variations from Database of Genomic Variants (DGV) for ENKD1 Gene

Disorders for ENKD1 Gene

No disorders were found for ENKD1 Gene.

No data available for UniProtKB/Swiss-Prot for ENKD1 Gene

Publications for ENKD1 Gene

  1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4
  2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. From ORFeome to biology: a functional genomics pipeline. (PMID: 15489336) Wiemann S. … Poustka A. (Genome Res. 2004) 3
  5. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3

Products for ENKD1 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ENKD1
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ENKD1
    • Block miRNA regulation of ENKD1 using miScript Target Protectors

    Sources for ENKD1 Gene

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