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Aliases for ENKD1 Gene

Aliases for ENKD1 Gene

  • Enkurin Domain Containing 1 2 3 5
  • C16orf48 3 4
  • Chromosome 16 Open Reading Frame 48 2
  • DAKV6410 3

External Ids for ENKD1 Gene

Previous HGNC Symbols for ENKD1 Gene

  • C16orf48

Summaries for ENKD1 Gene

GeneCards Summary for ENKD1 Gene

ENKD1 (Enkurin Domain Containing 1) is a Protein Coding gene.

Gene Wiki entry for ENKD1 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ENKD1 Gene

Genomics for ENKD1 Gene

Regulatory Elements for ENKD1 Gene

Promoters for ENKD1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ENKD1 on UCSC Golden Path with GeneCards custom track

Genomic Location for ENKD1 Gene

67,662,945 bp from pter
67,667,265 bp from pter
4,321 bases
Minus strand

Genomic View for ENKD1 Gene

Genes around ENKD1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ENKD1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ENKD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ENKD1 Gene

Proteins for ENKD1 Gene

  • Protein details for ENKD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Enkurin domain-containing protein 1
    Protein Accession:
    Secondary Accessions:
    • Q6UWD7

    Protein attributes for ENKD1 Gene

    346 amino acids
    Molecular mass:
    38759 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ENKD1 Gene


neXtProt entry for ENKD1 Gene

Proteomics data for ENKD1 Gene at MOPED

Post-translational modifications for ENKD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ENKD1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ENKD1 Gene

Domains & Families for ENKD1 Gene

Protein Domains for ENKD1 Gene


Graphical View of Domain Structure for InterPro Entry



  • Contains 1 enkurin domain.
  • Contains 1 enkurin domain.
genes like me logo Genes that share domains with ENKD1: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for ENKD1 Gene

Function for ENKD1 Gene

Phenotypes for ENKD1 Gene

GenomeRNAi human phenotypes for ENKD1:
genes like me logo Genes that share phenotypes with ENKD1: view

Animal Model Products

miRNA for ENKD1 Gene

miRTarBase miRNAs that target ENKD1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ENKD1 Gene

Localization for ENKD1 Gene

Subcellular locations from

Jensen Localization Image for ENKD1 Gene COMPARTMENTS Subcellular localization image for ENKD1 gene
Compartment Confidence
cytoskeleton 5
cytosol 3
nucleus 2
plasma membrane 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ENKD1 Gene

Pathways & Interactions for ENKD1 Gene

SuperPathways for ENKD1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ENKD1 Gene


No data available for Pathways by source and SIGNOR curated interactions for ENKD1 Gene

Drugs & Compounds for ENKD1 Gene

No Compound Related Data Available

Transcripts for ENKD1 Gene

Unigene Clusters for ENKD1 Gene

Enkurin domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ENKD1 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b · 9c
SP1: - - - -
SP2: - - - -
SP3: - -
SP4: - - -
SP5: - - -
SP6: - - - - - - -

Relevant External Links for ENKD1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ENKD1 Gene

mRNA expression in normal human tissues for ENKD1 Gene

mRNA differential expression in normal tissues according to GTEx for ENKD1 Gene

This gene is overexpressed in Pancreas (x4.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ENKD1 Gene

SOURCE GeneReport for Unigene cluster for ENKD1 Gene Hs.729159

genes like me logo Genes that share expression patterns with ENKD1: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ENKD1 Gene

Orthologs for ENKD1 Gene

This gene was present in the common ancestor of animals.

Orthologs for ENKD1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ENKD1 35
  • 87.54 (n)
  • 89.57 (a)
ENKD1 36
  • 89 (a)
(Canis familiaris)
Mammalia ENKD1 35
  • 87.73 (n)
  • 88.99 (a)
ENKD1 36
  • 89 (a)
(Mus musculus)
Mammalia Enkd1 35
  • 83.86 (n)
  • 84.64 (a)
Enkd1 16
Enkd1 36
  • 84 (a)
(Rattus norvegicus)
Mammalia Enkd1 35
  • 84.64 (n)
  • 86.09 (a)
(Monodelphis domestica)
Mammalia ENKD1 36
  • 55 (a)
(Ornithorhynchus anatinus)
Mammalia ENKD1 36
  • 58 (a)
(Pan troglodytes)
Mammalia ENKD1 36
  • 100 (a)
(Gallus gallus)
Aves C11H16ORF48 35
  • 65.41 (n)
  • 58.67 (a)
ENKD1 36
  • 53 (a)
(Anolis carolinensis)
Reptilia ENKD1 36
  • 53 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia enkd1 35
  • 55.23 (n)
  • 50.58 (a)
(Danio rerio)
Actinopterygii si:ch211-220d9.3 35
  • 57.19 (n)
  • 53.89 (a)
ENKD1 36
  • 49 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG11125 36
  • 19 (a)
Species with no ortholog for ENKD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ENKD1 Gene

Gene Tree for ENKD1 (if available)
Gene Tree for ENKD1 (if available)

Paralogs for ENKD1 Gene

No data available for Paralogs for ENKD1 Gene

Variants for ENKD1 Gene

Sequence variations from dbSNP and Humsavar for ENKD1 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs3833057 -- 67,663,886(+) CCCCC(-/C)ACACC intron-variant
rs5021812 -- 67,664,343(+) GGCTC(C/T)TAACA intron-variant
rs5021813 -- 67,664,269(+) TCCAC(C/T)TCAGT intron-variant
rs12103167 -- 67,663,335(+) GGCCC(A/G)GGAAC intron-variant
rs12599958 -- 67,663,737(+) AGGAC(C/G/T)TGCAG reference, synonymous-codon

Variation tolerance for ENKD1 Gene

Residual Variation Intolerance Score: 81.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.35; 53.73% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ENKD1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ENKD1 Gene

Disorders for ENKD1 Gene

Relevant External Links for ENKD1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ENKD1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ENKD1 Gene

Publications for ENKD1 Gene

  1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4 67
  2. Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. (PMID: 24722188) Corominas R. … Iakoucheva L.M. (Nat. Commun. 2014) 3
  3. Biological insights from 108 schizophrenia-associated genetic loci. (PMID: 25056061) (Nature 2014) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis. (PMID: 23264731) Fong K.W. … Chen J. (J. Cell Sci. 2013) 3

Products for ENKD1 Gene

Sources for ENKD1 Gene

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