Aliases for EN1 Gene
Aliases for EN1 Gene
External Ids for EN1 Gene
- HGNC: 3342
- Entrez Gene: 2019
- Ensembl: ENSG00000163064
- OMIM: 131290
- UniProtKB: Q05925
Previous GeneCards Identifiers for EN1 Gene
- GC02M116805
- GC02M117520
- GC02M119506
- GC02M119694
- GC02M119315
- GC02M111924
Summaries for EN1 Gene
-
Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008]
GeneCards Summary for EN1 Gene
EN1 (Engrailed Homeobox 1) is a Protein Coding gene. Diseases associated with EN1 include Tyrosinemia, Type Iii and Sudden Infant Death Syndrome. Among its related pathways are Neural Stem Cell Differentiation Pathways and Lineage-specific Markers and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding. An important paralog of this gene is EN2.
Additional gene information for EN1 Gene
- Monarch Initiative
- Search for EN1 at DataMed
- Search for EN1 at HumanCyc
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for EN1 Gene
Genomics for EN1 Gene
GeneHancer (GH) Regulatory Elements for EN1 Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH02I118846 | Promoter/Enhancer | 1.8 | EPDnew Ensembl ENCODE | 550.8 | 0.0 | -1 | 2.8 | PKNOX1 ZNF335 GATA2 EGR1 CREM ZNF362 USF2 ZNF398 SP1 NFIC | EN1 MARCO | |
GH02I118223 | Enhancer | 0.8 | Ensembl ENCODE | 11.9 | +623.4 | 623435 | 3 | PKNOX1 SUZ12 BMI1 CBX8 POLR2A IKZF1 MLLT1 EZH2 SPI1 | LOC105373578 EN1 LOC105373579 GC02M118174 | |
GH02I118222 | Enhancer | 0.6 | ENCODE | 11.9 | +626.0 | 625983 | 0.2 | CTCF ZNF654 ZNF511 TRIM22 SIN3A BMI1 REST RAD21 SMC3 ZNF143 | EN1 LOC105373578 LOC100506797 GC02M118174 | |
GH02I118842 | Enhancer | 0.8 | Ensembl ENCODE | 0.8 | +3.9 | 3905 | 4.4 | L3MBTL2 SUZ12 MAX BMI1 SP1 POLR2A E2F8 CTBP2 MGA EZH2 | EN1 LINC01956 | |
GH02I118855 | Enhancer | 0.8 | ENCODE | 0.4 | -7.6 | -7647 | 0.1 | ELF3 RB1 ARID4B ZNF2 ZNF48 RAD21 ZEB1 ZNF335 ARID2 ZNF143 | EN1 MARCO |
- Top Transcription factor binding sites by QIAGEN in the EN1 gene promoter:
Regulatory Element Products
Genomic Locations for EN1 Gene
- chr2:118,842,171-118,848,183
- (GRCh38/hg38)
- Size:
- 6,013 bases
- Orientation:
- Minus strand
- chr2:119,599,747-119,605,759
- (GRCh37/hg19)
Genomic View for EN1 Gene
- Cytogenetic band:
-
- 2q14.2 by Ensembl
- 2q14.2 by Entrez Gene
- 2q14.2 by HGNC


RefSeq DNA sequence for EN1 Gene
Proteins for EN1 Gene
-
Protein details for EN1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q05925-HME1_HUMAN
- Recommended name:
- Homeobox protein engrailed-1
- Protein Accession:
- Q05925
- Q4ZG44
Protein attributes for EN1 Gene
- Size:
- 392 amino acids
- Molecular mass:
- 40115 Da
- Quaternary structure:
- No Data Available
Protein Expression for EN1 Gene
Post-translational modifications for EN1 Gene
Other Protein References for EN1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for EN1
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-
Abcam antibodies for EN1
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-
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Protein Products
-
OriGene Purified Proteins for EN1
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- Search GeneTex for Proteins for EN1
-
Abcam proteins for EN1
Assay Products
- antibodies-online: Search results for available EN1 related products ranked by validation data
No data available for DME Specific Peptides for EN1 Gene
Domains & Families for EN1 Gene
Gene Families for EN1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for EN1 Gene
Suggested Antigen Peptide Sequences for EN1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q05925- Family:
-
- Belongs to the engrailed homeobox family.
Function for EN1 Gene
Molecular function for EN1 Gene
- GENATLAS Biochemistry:
- Drosophila segment-polarity gene engrailed homolog 1,homeo domain encoding gene,expressed in embryonic ventral limb ectoderm,regulator of the ventral limb patterning,inhibits WNT7A expression in ventral limb bud
Phenotypes From GWAS Catalog for EN1 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IDA | 21672318 |
GO:0001078 | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | IDA | 21672318 |
GO:0003677 | DNA binding | IEA | -- |
GO:0043565 | sequence-specific DNA binding | IEA | -- |
Phenotypes for EN1 Gene
- MGI mutant phenotypes for EN1:
-
inferred from 16 alleles
- nervous system phenotype
- normal phenotype
- homeostasis/metabolism phenotype
- muscle phenotype
- cardiovascular system phenotype
- mortality/aging
- immune system phenotype
- cellular phenotype
- behavior/neurological phenotype
- growth/size/body region phenotype
- endocrine/exocrine gland phenotype
- reproductive system phenotype
- integument phenotype
- embryo phenotype
- hematopoietic system phenotype
- skeleton phenotype
- pigmentation phenotype
- limbs/digits/tail phenotype
- GenomeRNAi human phenotypes for EN1:
Animal Models for EN1 Gene
Animal Model Products
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-
-
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-
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- Search ViGene Biosciences for EN1
CRISPR Products
-
OriGene CRISPR knockouts for EN1
- genomics-online: gRNA clones - Search results for available EN1 gene related products
- Applied Biological Materials CRISPR for EN1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for EN1
- GenScript: Design CRISPR guide RNA sequences for EN1
miRNA for EN1 Gene
- miRTarBase miRNAs that target EN1
-
- hsa-mir-128-2-5p (MIRT493967)
- hsa-mir-6781-5p (MIRT493968)
- hsa-mir-128-1-5p (MIRT493969)
- hsa-mir-4467 (MIRT493970)
- hsa-mir-139-3p (MIRT493971)
- hsa-mir-4746-3p (MIRT493972)
- hsa-mir-8072 (MIRT493973)
- hsa-mir-3960 (MIRT493974)
- hsa-mir-6746-5p (MIRT493975)
- hsa-let-7a-3p (MIRT735560)
- hsa-let-7b-3p (MIRT735589)
- hsa-let-7f-1-3p (MIRT735697)
- hsa-mir-1277-5p (MIRT736964)
- hsa-mir-300 (MIRT739606)
- hsa-mir-3184-5p (MIRT740855)
- hsa-mir-381-3p (MIRT742789)
- hsa-mir-423-5p (MIRT743253)
- hsa-mir-431-3p (MIRT743973)
- hsa-mir-4666a-3p (MIRT746784)
- hsa-mir-5011-5p (MIRT749524)
- hsa-mir-6069 (MIRT751666)
- hsa-mir-624-3p (MIRT752570)
- hsa-mir-98-3p (MIRT760929)
miRNA Products
- Search ViGene Biosciences for EN1
Inhibitory RNA Products
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- genomics-online: shRNA clones - Search results for available EN1 gene related products
-
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Clone Products
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available EN1 gene related products
- orf clones - Search results for available EN1 gene related products
- Applied Biological Materials Clones for EN1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for EN1
-
ViGene Biosciences adenoviral particle packaged cDNA for EN1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for EN1 gene
-
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No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for EN1 Gene
Localization for EN1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for EN1 Gene
- Nucleus.
- Nucleoli (3)
- Nucleus (3)
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IDA | 24399192 |
Pathways & Interactions for EN1 Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Neural Stem Cell Differentiation Pathways and Lineage-specific Markers | ||
2 | Dopaminergic Neurogenesis | ||
3 | Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways |
Pathways by source for EN1 Gene
2 BioSystems pathways for EN1 Gene
1 R&D Systems pathway for EN1 Gene
Interacting Proteins for EN1 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000122 | negative regulation of transcription by RNA polymerase II | IDA | 21672318 |
GO:0001501 | skeletal system development | TAS | 8684466 |
GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
GO:0007275 | multicellular organism development | IEA | -- |
GO:0008344 | adult locomotory behavior | IEA | -- |
No data available for SIGNOR curated interactions for EN1 Gene
Transcripts for EN1 Gene
mRNA/cDNA for EN1 Gene
- (1) REFSEQ mRNAs :
- (0) Additional mRNA sequences :
- -
- (6) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for EN1
- genomics-online: gRNA clones - Search results for available EN1 gene related products
- Applied Biological Materials CRISPR for EN1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for EN1
- GenScript: Design CRISPR guide RNA sequences for EN1
miRNA Products
- Search ViGene Biosciences for EN1
Inhibitory RNA Products
- Origene RNAi, shrna, and sirna products in human, mouse, rat for EN1
- Browse OriGene Inhibitory RNA Products For EN1
- genomics-online: shRNA clones - Search results for available EN1 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for EN1 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for EN1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for EN1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available EN1 gene related products
- orf clones - Search results for available EN1 gene related products
- Applied Biological Materials Clones for EN1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for EN1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Brain (Nervous System)
- Fetal Dopaminergic Neurons Ventral Tegmental Area
- Adult Dopaminergic Neurons Substantia Nigra pars Compacta
- Dopaminergic Progenitor Cells Ventral Tegmental Area
- Adult Dopaminergic Neurons Ventral Tegmental Area
- Early Caudal Floor Plate Cells Diencephalic Floor Plate
-
Dermis (Integumentary System)
- Dermal Mesenchyme Cells Ventral Subectodermal Mesenchyme
- Dermal Fibroblasts Ventral Dermis
- Dermal Progenitor Cells Thoracic Dorsomedial Dermomyotome Lip
- Dermal Progenitor Cells Somatopleure
- Dermal Progenitor Cells Sacral Dorsomedial Dermomyotome Lip
-
Neurons
- Fetal Dopaminergic Neurons Ventral Tegmental Area
- Adult Dopaminergic Neurons Substantia Nigra pars Compacta
- Dopaminergic Progenitor Cells Ventral Tegmental Area
- Adult Dopaminergic Neurons Ventral Tegmental Area
- Dopaminergic Progenitor Cells Substantia Nigra pars Compacta
-
Somite (Muscoskeletal System)
- Dermal Progenitor Cells Thoracic Dorsomedial Dermomyotome Lip
- Dermal Progenitor Cells Sacral Dorsomedial Dermomyotome Lip
- Dermal Progenitor Cells Lumbar Central Dermomyotome
- Dermal Progenitor Cells Thoracic Central Dermomyotome
- Dermal Progenitor Cells Sacral Central Dermomyotome
-
Neural Tube (Nervous System)
- Late Caudal Floor Plate Cells Diencephalic Floor Plate
- Early Caudal Floor Plate Cells Diencephalic Floor Plate
- Isthmus Cells Neural Plate
- Early Floor Plate Cells Mesencephalic Floor Plate
- Meso-diencephalic Dopaminergic Precursor Cells Diencephalic Ventricular Zone
- Dopaminergic Neurons (Nervous System)
-
Fibroblasts
- Dermal Fibroblasts Ventral Dermis
- Dermal Fibroblasts Cranial Dermis
- Dermal Fibroblasts Dorsal Dermis
-
Lateral Plate Mesoderm (Gastrulation Derivatives)
- Dermal Progenitor Cells Somatopleure
-
Neural Ectoderm (Nervous System)
- Isthmus Cells Neural Plate
- Motor Neurons (Nervous System)
- Spinal Cord (Nervous System)
mRNA differential expression in normal tissues according to GTEx for EN1 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for EN1 Gene
NURSA nuclear receptor signaling pathways regulating expression of EN1 Gene:
EN1SOURCE GeneReport for Unigene cluster for EN1 Gene:
Hs.271977Evidence on tissue expression from TISSUES for EN1 Gene
- Nervous system(2.7)
Primer Products
-
OriGene qPCR primer pairs for EN1
- genomics-online: primer clones - Search results for available EN1 gene related products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for EN1 Gene
Orthologs for EN1 Gene
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | EN1 33 34 |
|
||
dog (Canis familiaris) |
Mammalia | EN1 34 |
|
OneToOne | |
platypus (Ornithorhynchus anatinus) |
Mammalia | EN1 34 |
|
OneToOne | |
cow (Bos Taurus) |
Mammalia | EN1 33 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | En1 33 |
|
||
mouse (Mus musculus) |
Mammalia | En1 33 16 34 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | EN1 34 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | EN1 34 |
|
OneToOne | |
lizard (Anolis carolinensis) |
Reptilia | EN1 34 |
|
OneToOne | |
African clawed frog (Xenopus laevis) |
Amphibia | en1-A 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | eng1b 33 34 |
|
||
eng1a 34 |
|
OneToMany | |||
fruit fly (Drosophila melanogaster) |
Insecta | en 35 34 |
|
||
inv 34 35 |
|
ManyToMany | |||
worm (Caenorhabditis elegans) |
Secernentea | ceh-16 34 |
|
OneToMany | |
sea squirt (Ciona savignyi) |
Ascidiacea | CSA.4370 34 |
|
OneToMany |
- Species where no ortholog for EN1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Paralogs for EN1 Gene
Variants for EN1 Gene
SNP ID | Clin | Chr 02 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs749569923 | likely-benign, not specified | 118,846,940(-) | T/C/G | coding_sequence_variant, synonymous_variant | |
rs1000120526 | -- | 118,843,466(-) | G/A | intron_variant | |
rs1000996333 | -- | 118,849,589(-) | C/T | upstream_transcript_variant | |
rs1001293117 | -- | 118,842,766(-) | A/C | 3_prime_UTR_variant | |
rs1001346452 | -- | 118,842,442(-) | G/A | 3_prime_UTR_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
nsv1072021 | CNV | deletion | 25765185 |
nsv1118875 | CNV | deletion | 24896259 |
nsv582783 | CNV | gain | 21841781 |
nsv954799 | CNV | deletion | 24416366 |
Additional Variant Information for EN1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for EN1 Gene
Disorders for EN1 Gene
Disorder | Aliases | PubMed IDs |
---|---|---|
tyrosinemia, type iii |
|
|
sudden infant death syndrome |
|
|
salivary gland adenoid cystic carcinoma |
|
|
benign paroxysmal positional nystagmus |
|
|
Additional Disease Information for EN1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for EN1 Gene
Publications for EN1 Gene
- Polymorphisms of coding trinucleotide repeats of homeogenes in neurodevelopmental psychiatric disorders. (PMID: 19018235) Laroche F … Robel L (Psychiatric genetics 2008) 3 22 44 58
- Sudden infant death syndrome: case-control frequency differences at genes pertinent to early autonomic nervous system embryologic development. (PMID: 15240857) Weese-Mayer DE … Marazita ML (Pediatric research 2004) 3 22 44 58
- Cloning and sequence comparison of the mouse, human, and chicken engrailed genes reveal potential functional domains and regulatory regions. (PMID: 1363401) Logan C … Joyner AL (Developmental genetics 1992) 3 4 22 58
- Association of transcription factor polymorphisms PITX3 and EN1 with Parkinson's disease. (PMID: 19345444) Haubenberger D … Zimprich A (Neurobiology of aging 2011) 3 44 58
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 44 58
Products for EN1 Gene
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- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 26 available EN1 Antibodies ranked by validation data
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- genomics-online: gRNA clones - Search results for available EN1 gene related products
- genomics-online: primer clones - Search results for available EN1 gene related products
- genomics-online: shRNA clones - Search results for available EN1 gene related products
Sources for EN1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew