ELP3 Gene
protein-coding GIFtS: 54
GCID: GC08P028006
|
|
elongator acetyltransferase complex subunit 3(Previous name: elongation protein 3 homolog (S. cerevisiae) )
| |
Aliases for ELP3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Elongator Acetyltransferase Complex Subunit 31 2 | | FLJ104221 | | KAT91 2 5 | | Elongation Protein 3 Homolog (S. Cerevisiae)1 | | HELP31 | | Elongation Protein 3 Homolog2 | | EC 2.3.1.483 8 | | Elongator Complex Protein 32 |
Export aliases for ELP3 gene to outside databasesPrevious GC identifers: GC08P027733 GC08P028455 GC08P027972 GC08P026496 |
Summaries for ELP3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for ELP3: ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcriptelongation and also regulates the maturation of projection neurons (Creppe et al., 2009 (PubMed 19185337)).(suppliedby OMIM, Apr 2009) UniProtKB/Swiss-Prot: ELP3_HUMAN, Q9H9T3Function: Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a componentof the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a rolein chromatin remodeling and is involved in acetylation of histones H3 and probably H4. May also have amethyltransferase activity. Involved in cell migration Gene Wiki entry for ELP3
|
Genomic Views for ELP3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_167187.1
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ELP3 gene promoter: USF1 HOXA3 IRF-1 HNF-3beta IRF-2 POU2F1 POU2F1a Cart-1 Other transcription factors
Search SABiosciences Chromatin IP Primers for ELP3
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ELP3 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8p21.1 Ensembl cytogenetic band: 8p21.1 HGNC cytogenetic band: 8p21.1ELP3 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08P028006: view genomic region
(about GC identifiers)
Start:
|
27,947,190 bp from pter |
End:
|
28,048,673 bp from pter |
Size:
|
101,484 bases |
Orientation:
|
plus strand |
|
Proteins for ELP3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: ELP3_HUMAN, Q9H9T3 (See
protein sequence)Recommended Name: Elongator complex protein 3 Size: 547 amino acids; 62259 Da
Cofactor: Binds 1 4Fe-4S cluster. The cluster is coordinated with 3 cysteines and an exchangeableS-adenosyl-L-methionine (By similarity)
Subunit: Component of the RNA polymerase II elongator complex (Elongator), which consists of IKBKAP/ELP1, STIP1/ELP2,ELP3, ELP4, ELP5 and ELP6. IKBKAP/ELP1, STIP1/ELP2 and ELP3 form the Elongator core complex. Elongator associates withthe C-terminal domain (CTD) of Pol II largest subunit. Interacts with IKBKAP/ELP1
Subcellular location: Isoform 1: Nucleus
Subcellular location: Isoform 2: Cytoplasm. Nucleus
Sequence caution: Sequence=BAA91600.1; Type=Miscellaneous discrepancy; Note=Aberrant splicing; Sequence=CAH10573.1;Type=Frameshift; Positions=279;
Secondary accessions: Q53G84 Q6AWB0 Q9BVF7 Q9NVZ1Alternative splicing: 2 isoforms: Q9H9T3-1 Q9H9T3-2 Explore the universe of human proteins at neXtProt for ELP3: NX_Q9H9T3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H9T3 4/23 DME Specific Peptides for ELP3 (Q9H9T3) (see all 23)
ELP3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_060561.3 ENSEMBL proteins: ENSP00000429446 ENSP00000428449 ENSP00000428532 ENSP00000256398 ENSP00000430253 ENSP00000429180 ENSP00000429465 ENSP00000428357 ENSP00000430681 ENSP00000429248 ENSP00000429573 ENSP00000427833 ENSP00000430942 ENSP00000369711 ENSP00000445558 ENSP00000439242 Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
ELP3 for ontologies About GeneDecksing
ELP3 Antibody Products: Assay Products for ELP3: |
Protein
Domains / Families for ELP3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ELP3 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q9H9T3ProtoNet protein and cluster: Q9H9T3 2 Blocks protein families: IPB000182 GCN5-related N-acetyltransferase IPB006638 Elongator protein 3/MiaB/NifB
UniProtKB/Swiss-Prot: ELP3_HUMAN, Q9H9T3Similarity: Belongs to the ELP3 familySimilarity: Contains 1 N-acetyltransferase domain |
Function for ELP3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: ELP3_HUMAN, Q9H9T3Function: Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a componentof the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a rolein chromatin remodeling and is involved in acetylation of histones H3 and probably H4. May also have amethyltransferase activity. Involved in cell migrationCatalytic activity: Acetyl-CoA + [histone] = CoA + acetyl-[histone]Enzyme Number (IUBMB): EC 2.3.1.481 2
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ELP3 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ELP3 (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ELP3 (NM_018091) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ELP3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ELP3  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ELP3 |
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
ELP3 for ontologies About GeneDecksing
Animal Models: 1 MGI phenotypic allele for Elp3 (no phenotypes)
ELP3 for phenotypes About GeneDecksing
|
Pathways & Interactions for ELP3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Chromatin Regulation / Acetylation | |
Pathway sources See GeneCards unified pathways Show all pathways
1
Cell Signaling Technology (CST) Pathway for ELP3
ELP3 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ELP3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/163 Interacting proteins for ELP3 (Q9H9T31, 3 ENSP000002563984) via UniProtKB, MINT, STRING, and/or I2D (see all 163)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006357 | regulation of transcription from RNA polymerase II promoter |
TAS | 11714725 | | GO:0006368 | transcription elongation from RNA polymerase II promoter |
IDA | 11714725 | | GO:0030335 | positive regulation of cell migration |
ISS | -- |
ELP3 for ontologies About GeneDecksing
|
Drugs & Compounds for ELP3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for ELP3
3 HMDB Compounds for ELP3 About this table Search CenterWatch for drugs/clinical trials and news about ELP3 
|
Transcripts for ELP3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for ELP3 gene: NM_018091.5 Unigene Cluster for ELP3: Elongator acetyltransferase complex subunit 3 Hs.491336 [show with all ESTs]Unigene Representative Sequence: NM_01809118/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21): ENST00000520270 ENST00000521015(uc003xgn.4) ENST00000521570 ENST00000256398(uc003xgo.4 uc011laq.2 uc011lar.2 uc011las.2 uc011lat.2) ENST00000523687 ENST00000523760 ENST00000524103 ENST00000518112 ENST00000519261 ENST00000524024 ENST00000521938 ENST00000520288 ENST00000521099 ENST00000522063 ENST00000520110 ENST00000520011 ENST00000523357 ENST00000517975
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ELP3 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ELP3 (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ELP3 (NM_018091) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ELP3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ELP3  |
Additional cDNA sequence: AK001284.1 AK022626.1 AK223047.1 AK293424.1 AK295574.1 AK296475.1 AK298265.1 AK302140.1 AK315985.1 AK316053.1 AL834273.1 BC001240.1 BX648011.1 13 DOTS entries: DT.454535 DT.100811712 DT.101983588 DT.100811719 DT.100802493 DT.121480432 DT.95288288 DT.97861876 DT.97776032 DT.86839177 DT.86855236 DT.97810312 DT.97822259 24/214 AceView cDNA sequences (see all 214): BP378418 AI810734 BQ064911 AA922599 BQ440313 AA580821 BP366303 BU632220 AA411348 CK725091 AU186102 AW439052 CR618264 AI288057 BX280249 BM930840 AA337527 BM824411 CB119076 BX390272 CB216924 BM663362 AI370380 AL834273 GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ELP3 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ | 15a | · | 15b | ^ | 16 | ^ | 17a | · | 17b | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | - |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for ELP3
|
Expression for ELP3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ELP3 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CAATAAAACT
About this image See ELP3 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ELP3
SOURCE GeneReport for Unigene cluster: Hs.491336 SABiosciences Custom PCR Arrays for ELP3
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ELP3 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ELP3 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ELP3 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ELP3 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ELP3 |
Orthologs for ELP3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ELP3 gene from 10/41 species (see all 41) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Elp31 , 5 |
elongation protein 3 homolog (S. cerevisiae)5 elongator acetyltransferase complex subunit 31 |
88.06(n)1 95.8(a)1 |
  |
14 (34.33 cM)5 741951 NM_028811.31 NP_083087.11 655304465 |
chicken (Gallus gallus) |
Aves |
ELP31 |
elongation protein 3 homolog (S. cerevisiae) |
79.24(n) 91.58(a) |
  |
422021 NM_001039293.1 NP_001034382.1 |
lizard (Anolis carolinensis) |
Reptilia |
ELP36 |
-- |
91(a) |
1 ↔ 1 |
GL343529.1(139732-267657) |
African clawed frog (Xenopus laevis) |
Amphibia |
Xl.167502 |
Xenopus laevis transcribed sequence with moderate similarity more |
77.43(n) |
  |
BU913269.1 |
zebrafish (Danio rerio) |
Actinopterygii |
elp31 |
elongation protein 3 homolog (S. cerevisiae) |
75.84(n) 90.46(a) |
  |
541509 NM_001014322.2 NP_001014344.2 |
fruit fly (Drosophila melanogaster) |
Insecta |
Elp31 |
Elongator complex protein 3 |
67.4(n) 82.63(a) |
  |
33649 NM_134990.3 NP_608834.1 |
worm (Caenorhabditis elegans) |
Secernentea |
elpc-31 |
Protein ELPC-3 |
66.42(n) 80.07(a) |
  |
179669 NM_073654.3 NP_506055.2 |
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes |
ELP3(YPL086C)4 ELP31 |
Subunit of Elongator complex, which is required for more4 Elp3p1 |
65.8(n)1 75.23(a)1 |
  |
16(386446-384773)4 8560191, 4 NP_015239.11, 4 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
ELO31 |
Elongator complex protein 3 |
65.55(n) 73.98(a) |
  |
835098 NM_124412.2 NP_568725.1 |
rice (Oryza sativa) |
Liliopsida |
Os.175162 |
Oryza sativa (japonica cultivar-group) cDNA cloneJ more |
71.94(n) |
  |
AK122179.1 |
ENSEMBL Gene Tree for ELP3 (if available) TreeFam Gene Tree for ELP3 (if available)  |
Paralogs for ELP3 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for ELP3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 8 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for ELP3 (27947190 - 28048673 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for ELP3: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ELP3 |
|
Disorders
/ Diseases for ELP3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ELP3 for disorders About GeneDecksing
OMIM gene information: 612722
OMIM disorders: --
4 diseases for ELP3: About MalaCardsriley-day syndrome dysautonomia neuronitis malaria 1 disease from the University of Copenhagen DISEASES database for ELP3:Riley-Day syndrome Human Genome Epidemiology (HuGE) Navigator: ELP3 (2 documents) Export disorders for ELP3 gene to outside databases
|
Publications for ELP3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ELP3 gene, integrated from 9 sources (see all 38): (articles sorted by number of sources associating them with ELP3) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Purification and characterization of the human elongator complex. (PubMed id 11714725)1, 2, 3 Hawkes N.A.... Svejstrup J.Q. (2002)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Human Elongator facilitates RNA polymerase II transcription through chromatin. (PubMed id 11818576)1, 2 Kim J.H.... Reinberg D. (2002)
- hELP3 subunit of the Elongator complex regulates the transcription of HSP70 gene in human cells. (PubMed id 17558451)1, 9 Han Q....Lu J. (2007)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicit y and migration of melanoma cells as subunits of Elongator. (PubMed id 22854966)2 Close P....Chariot A. (2012)
- Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization. (PubMed id 22002106)2 Ahmad Y.... Lamond A.I. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
|
External Searches for ELP3 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing ELP3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ELP3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ELP3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for ELP3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ELP3 gene: Search GeneIP for patents involving ELP3
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for ELP3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
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| | | | OriGene Antibodies for ELP3 | | OriGene shRNA RFP for ELP3 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ELP3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ELP3 | | OriGene Protein Over-expression Lysate for ELP3 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for ELP3 | | OriGene 3'-UTR Clone for ELP3 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ELP3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ELP3 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for ELP3 | | OriGene Custom Protein Services for ELP3 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ELP3 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ELP3 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ELP3 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ELP3 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ELP3 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ELP3 |
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| Antibodies & Assays for ELP3  |
| | | Search Tocris compounds for ELP3 |
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 | | ELP3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ELP3 |
|  |  |  | | | ThermoFisher Antibodies for ELP3 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ELP3 |
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