Aliases for ELP2 Gene
External Ids for ELP2 Gene
Previous HGNC Symbols for ELP2 Gene
Previous GeneCards Identifiers for ELP2 Gene
The protein encoded by this gene is a core subunit of the elongator complex, a histone acetyltransferase complex that associates with RNA polymerase II. In addition to histone acetylation, the encoded protein effects transcriptional elongation and may help remodel chromatin. [provided by RefSeq, May 2016]
GeneCards Summary for ELP2 Gene
ELP2 (Elongator Acetyltransferase Complex Subunit 2) is a Protein Coding gene. Among its related pathways are Chromatin organization and TGF-Beta Pathway. GO annotations related to this gene include protein kinase binding and RNA polymerase II core binding.
UniProtKB/Swiss-Prot for ELP2 Gene
Regulates the ligand-dependent activation of STAT3.
Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.