Aliases for ELOVL7 Gene
External Ids for ELOVL7 Gene
Previous GeneCards Identifiers for ELOVL7 Gene
GeneCards Summary for ELOVL7 Gene
ELOVL7 (ELOVL Fatty Acid Elongase 7) is a Protein Coding gene. Among its related pathways are Fatty acid elongation and Metabolism. GO annotations related to this gene include transferase activity. An important paralog of this gene is ELOVL1.
UniProtKB/Swiss-Prot for ELOVL7 Gene
Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate in the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.