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Aliases for ELOVL5 Gene

Aliases for ELOVL5 Gene

  • ELOVL Fatty Acid Elongase 5 2 3 4 5
  • ELOVL Family Member 5, Elongation Of Long Chain Fatty Acids (FEN1/Elo2, SUR4/Elo3-Like, Yeast) 2 3
  • Very Long Chain 3-Ketoacyl-CoA Synthase 5 3 4
  • Very Long Chain 3-Oxoacyl-CoA Synthase 5 3 4
  • 3-Keto Acyl-CoA Synthase ELOVL5 3 4
  • Spinocerebellar Ataxia 38 2 3
  • Fatty Acid Elongase 1 3 4
  • ELOVL FA Elongase 5 3 4
  • HELO1 3 4
  • Homolog Of Yeast Long Chain Polyunsaturated Fatty Acid Elongation Enzyme 2 3
  • Elongation Of Very Long Chain Fatty Acids Protein 5 3
  • EC 2.3.1.199 4
  • DJ483K16.1 3
  • ELOVL2 4
  • SCA38 3

External Ids for ELOVL5 Gene

Previous HGNC Symbols for ELOVL5 Gene

  • SCA38

Previous GeneCards Identifiers for ELOVL5 Gene

  • GC06M053074
  • GC06M053179
  • GC06M052964
  • GC06M053132

Summaries for ELOVL5 Gene

Entrez Gene Summary for ELOVL5 Gene

  • This gene belongs to the ELO family. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum. This protein is involved in the elongation of long-chain polyunsaturated fatty acids. Mutations in this gene have been associated with spinocerebellar ataxia-38 (SCA38). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]

GeneCards Summary for ELOVL5 Gene

ELOVL5 (ELOVL Fatty Acid Elongase 5) is a Protein Coding gene. Diseases associated with ELOVL5 include Spinocerebellar Ataxia 38 and Ataxia. Among its related pathways are Fatty acid elongation and Metabolism. GO annotations related to this gene include fatty acid elongase activity. An important paralog of this gene is ELOVL2.

UniProtKB/Swiss-Prot for ELOVL5 Gene

  • Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate in the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.

Gene Wiki entry for ELOVL5 Gene

Additional gene information for ELOVL5 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ELOVL5 Gene

Genomics for ELOVL5 Gene

Regulatory Elements for ELOVL5 Gene

Enhancers for ELOVL5 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06H053306 1.9 FANTOM5 Ensembl ENCODE dbSUPER 20.3 +38.7 38738 8 HDGF PKNOX1 FOXA2 ATF1 FEZF1 DMAP1 YY1 TCF12 ZNF766 GATA2 EFHC1 ELOVL5 RPL31P28 FBXO9 PIR59384 RPS16P5
GH06H053299 1.4 Ensembl ENCODE dbSUPER 18.6 +47.3 47314 5 FOXA2 MLX ARID4B DMAP1 THRB RAD21 RARA YY1 RUNX3 CREM ELOVL5 RPL31P28 PIR59384 RPS16P5
GH06H053321 1.4 Ensembl ENCODE dbSUPER 18.3 +26.2 26183 2 PKNOX1 FOXA2 FEZF1 ZNF48 RARA ZSCAN5C SCRT2 FOS MIXL1 ZNF202 ELOVL5 EFHC1 RPL31P28 RPS16P5 PIR59384
GH06H053332 1.8 FANTOM5 Ensembl ENCODE dbSUPER 12.9 +13.2 13182 6 HDGF FOXA2 SIN3A BMI1 BATF SCRT2 ATF7 ETV6 RUNX3 CREM ELOVL5 FBXO9 RPS16P5 PIR59384
GH06H053432 1.7 FANTOM5 Ensembl ENCODE dbSUPER 11 -83.9 -83853 1 PKNOX1 FOXA2 MLX ARID4B YY1 FOS SP5 MXD4 REST PPARG RPL31P28 ELOVL5 NANOGP3 LOC105375095
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ELOVL5 on UCSC Golden Path with GeneCards custom track

Promoters for ELOVL5 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000198021 679 2600 MLX ARID4B SIN3A DMAP1 YBX1 YY1 ZNF143 ZNF207 FOS SP3

Genomic Location for ELOVL5 Gene

Chromosome:
6
Start:
53,267,398 bp from pter
End:
53,349,179 bp from pter
Size:
81,782 bases
Orientation:
Minus strand

Genomic View for ELOVL5 Gene

Genes around ELOVL5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ELOVL5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ELOVL5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ELOVL5 Gene

Proteins for ELOVL5 Gene

  • Protein details for ELOVL5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NYP7-ELOV5_HUMAN
    Recommended name:
    Elongation of very long chain fatty acids protein 5
    Protein Accession:
    Q9NYP7
    Secondary Accessions:
    • B4DZJ2
    • F6SH78
    • Q59EL3
    • Q5TGH5
    • Q6NXE7
    • Q7L2S5
    • Q8NCG4
    • Q9UI22

    Protein attributes for ELOVL5 Gene

    Size:
    299 amino acids
    Molecular mass:
    35293 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAF16688.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAC11178.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ELOVL5 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ELOVL5 Gene

Post-translational modifications for ELOVL5 Gene

  • Ubiquitination at isoforms=2, 313 and isoforms=2267
  • Modification sites at PhosphoSitePlus

Other Protein References for ELOVL5 Gene

No data available for DME Specific Peptides for ELOVL5 Gene

Domains & Families for ELOVL5 Gene

Gene Families for ELOVL5 Gene

Human Protein Atlas (HPA):
  • Disease related genes
  • Enzymes
  • Potential drug targets
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for ELOVL5 Gene

Suggested Antigen Peptide Sequences for ELOVL5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9NYP7

UniProtKB/Swiss-Prot:

ELOV5_HUMAN :
  • Belongs to the ELO family. ELOVL5 subfamily.
Family:
  • Belongs to the ELO family. ELOVL5 subfamily.
genes like me logo Genes that share domains with ELOVL5: view

Function for ELOVL5 Gene

Molecular function for ELOVL5 Gene

UniProtKB/Swiss-Prot CatalyticActivity:
A very-long-chain acyl-CoA + malonyl-CoA = CoA + a very-long-chain 3-oxoacyl-CoA + CO(2).
UniProtKB/Swiss-Prot Function:
Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate in the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.

Enzyme Numbers (IUBMB) for ELOVL5 Gene

Phenotypes From GWAS Catalog for ELOVL5 Gene

Gene Ontology (GO) - Molecular Function for ELOVL5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 20937905
GO:0009922 fatty acid elongase activity IDA,IEA 20427700
GO:0016740 transferase activity IEA --
GO:0102336 3-oxo-arachidoyl-CoA synthase activity IEA --
GO:0102337 3-oxo-cerotoyl-CoA synthase activity IEA --
genes like me logo Genes that share ontologies with ELOVL5: view
genes like me logo Genes that share phenotypes with ELOVL5: view

Human Phenotype Ontology for ELOVL5 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for ELOVL5
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Animal Models , Transcription Factor Targets and HOMER Transcription for ELOVL5 Gene

Localization for ELOVL5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ELOVL5 Gene

Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell projection, dendrite. Note=In Purkinje cells, the protein localizes to the soma and proximal portion of the dendritic tree. {ECO:0000255 HAMAP-Rule:MF_03205, ECO:0000269 PubMed:25065913}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ELOVL5 gene
Compartment Confidence
endoplasmic reticulum 5
plasma membrane 3
peroxisome 2
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Endoplasmic reticulum (4)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ELOVL5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum IEA,IDA 20937905
GO:0005789 endoplasmic reticulum membrane TAS --
GO:0016020 membrane IEA,IDA 19946888
GO:0016021 integral component of membrane IEA --
GO:0030176 integral component of endoplasmic reticulum membrane IBA --
genes like me logo Genes that share ontologies with ELOVL5: view

Pathways & Interactions for ELOVL5 Gene

genes like me logo Genes that share pathways with ELOVL5: view

UniProtKB/Swiss-Prot Q9NYP7-ELOV5_HUMAN

  • Pathway: Lipid metabolism; polyunsaturated fatty acid biosynthesis.

Interacting Proteins for ELOVL5 Gene

Selected Interacting proteins: Q9NYP7-ELOV5_HUMAN for ELOVL5 Gene via IID

Gene Ontology (GO) - Biological Process for ELOVL5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006629 lipid metabolic process IEA --
GO:0006631 fatty acid metabolic process IEA --
GO:0006633 fatty acid biosynthetic process IEA --
GO:0006636 unsaturated fatty acid biosynthetic process IEA --
GO:0019367 fatty acid elongation, saturated fatty acid IEA,IBA --
genes like me logo Genes that share ontologies with ELOVL5: view

No data available for SIGNOR curated interactions for ELOVL5 Gene

Drugs & Compounds for ELOVL5 Gene

(3) Drugs for ELOVL5 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Carbon dioxide Approved, Vet_approved Pharma 0
Malonyl-CoA Experimental Pharma 0
Coenzyme A Nutra 0
genes like me logo Genes that share compounds with ELOVL5: view

Transcripts for ELOVL5 Gene

Unigene Clusters for ELOVL5 Gene

ELOVL fatty acid elongase 5:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for ELOVL5
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for ELOVL5 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b · 12c ^ 13 ^ 14a ·
SP1: - - - - - - - - -
SP2: - - - - - - -
SP3: - - - - - - - - - -
SP4: - - - - - - -
SP5: - - - - -
SP6: - - - -
SP7: - - - - - - - - - -
SP8: - - - - - - - -
SP9: - - - - - -
SP10: - - - - - - - -
SP11: - - - - -
SP12: - -
SP13: - - - - - - - - - - - - - - - - - - - -
SP14: - -

ExUns: 14b ^ 15a · 15b · 15c · 15d · 15e · 15f
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13: -
SP14: -

Relevant External Links for ELOVL5 Gene

GeneLoc Exon Structure for
ELOVL5
ECgene alternative splicing isoforms for
ELOVL5

Expression for ELOVL5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ELOVL5 Gene

Protein differential expression in normal tissues from HIPED for ELOVL5 Gene

This gene is overexpressed in Breast (22.2) and Liver (6.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ELOVL5 Gene



Protein tissue co-expression partners for ELOVL5 Gene

NURSA nuclear receptor signaling pathways regulating expression of ELOVL5 Gene:

ELOVL5

SOURCE GeneReport for Unigene cluster for ELOVL5 Gene:

Hs.520189

mRNA Expression by UniProt/SwissProt for ELOVL5 Gene:

Q9NYP7-ELOV5_HUMAN
Tissue specificity: Ubiquitous. Highly expressed in the adrenal gland and testis. Weakly expressed in prostate, lung and brain. Expressed in the cerebellum.

Evidence on tissue expression from TISSUES for ELOVL5 Gene

  • Nervous system(5)
  • Liver(4.7)
  • Skin(4.6)
  • Eye(4.4)
  • Kidney(2.9)
  • Blood(2.8)
  • Intestine(2.7)
  • Lung(2.5)
  • Spleen(2.2)
  • Heart(2)

Phenotype-based relationships between genes and organs from Gene ORGANizer for ELOVL5 Gene

Germ Layers:
  • ectoderm
  • mesoderm
Systems:
  • nervous
  • skeletal muscle
  • skeleton
Organs:
Head and neck:
  • brain
  • cerebellum
  • eye
  • head
Limb:
  • lower limb
  • upper limb
General:
  • peripheral nerve
  • peripheral nervous system
  • spinal cord
genes like me logo Genes that share expression patterns with ELOVL5: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for ELOVL5 Gene

Orthologs for ELOVL5 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ELOVL5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ELOVL5 33 34
  • 99.55 (n)
dog
(Canis familiaris)
Mammalia ELOVL5 33 34
  • 91.86 (n)
rat
(Rattus norvegicus)
Mammalia Elovl5 33
  • 88.63 (n)
oppossum
(Monodelphis domestica)
Mammalia ELOVL5 34
  • 88 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ELOVL5 33 34
  • 87.63 (n)
mouse
(Mus musculus)
Mammalia Elovl5 33 16 34
  • 87.29 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia ELOVL5 34
  • 84 (a)
OneToOne
chicken
(Gallus gallus)
Aves ELOVL5 33 34
  • 80.9 (n)
lizard
(Anolis carolinensis)
Reptilia ELOVL5 34
  • 83 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia elovl5 33
  • 73.9 (n)
Str.8538 33
African clawed frog
(Xenopus laevis)
Amphibia Xl.18919 33
zebrafish
(Danio rerio)
Actinopterygii elovl5 33 34
  • 70.9 (n)
zgc63549 33
fruit fly
(Drosophila melanogaster)
Insecta Elo68alpha 34
  • 33 (a)
ManyToMany
Elo68beta 34
  • 32 (a)
ManyToMany
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AFR624W 33
  • 45.43 (n)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0C03542g 33
  • 42.34 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes FEN1 33
  • 41.79 (n)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G06470 33
  • 55.8 (n)
rice
(Oryza sativa)
Liliopsida Os03g0701500 33
  • 45.74 (n)
bread mold
(Neurospora crassa)
Ascomycetes NCU06694 33
  • 48.51 (n)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPAC1B2.03c 33
  • 43.29 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 34 (a)
ManyToMany
Species where no ortholog for ELOVL5 was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ELOVL5 Gene

ENSEMBL:
Gene Tree for ELOVL5 (if available)
TreeFam:
Gene Tree for ELOVL5 (if available)

Paralogs for ELOVL5 Gene

Paralogs for ELOVL5 Gene

(4) SIMAP similar genes for ELOVL5 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ELOVL5: view

Variants for ELOVL5 Gene

Sequence variations from dbSNP and Humsavar for ELOVL5 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs587777670 Pathogenic, Spinocerebellar ataxia 38 (SCA38) [MIM:615957] 53,270,660(+) ACCAA(A/C/T)CAAGA reference, missense, stop-gained
rs587777671 Pathogenic, Spinocerebellar ataxia 38 (SCA38) [MIM:615957] 53,291,808(+) TGTGA(C/G)TCCAA reference, missense
rs41273880 Uncertain significance 53,270,651(+) GGAAA(C/T)ACAAC reference, synonymous-codon, missense
rs3830806 untested 53,269,306(+) CACAG(-/ACAG)TTTTC intron-variant
rs397822160 untested 53,269,310(+) CACAG(-/ACAG)TTTTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ELOVL5 Gene

Variant ID Type Subtype PubMed ID
dgv3514e59 CNV tandem duplication 20981092
esv2763940 CNV gain+loss 21179565
esv3305967 CNV mobile element insertion 20981092
esv3359371 CNV duplication 20981092
esv3390913 CNV insertion 20981092
esv3609024 CNV loss 21293372
nsv1033994 CNV gain 25217958
nsv1077726 CNV insertion 25765185
nsv1114807 CNV deletion 24896259
nsv1119536 CNV insertion 24896259
nsv1143150 CNV tandem duplication 24896259
nsv472566 CNV novel sequence insertion 20440878

Variation tolerance for ELOVL5 Gene

Residual Variation Intolerance Score: 30.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.83; 17.33% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ELOVL5 Gene

Human Gene Mutation Database (HGMD)
ELOVL5
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ELOVL5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ELOVL5 Gene

Disorders for ELOVL5 Gene

MalaCards: The human disease database

(4) MalaCards diseases for ELOVL5 Gene - From: HGMD, OMIM, ClinVar, Orphanet, Swiss-Prot, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
spinocerebellar ataxia 38
  • spinocerebellar ataxia type 38
ataxia
glaucoma, normal tension
  • low tension glaucoma
retinitis pigmentosa
  • retinitis pigmentosa 1
- elite association - COSMIC cancer census association via MalaCards

UniProtKB/Swiss-Prot

ELOV5_HUMAN
  • Spinocerebellar ataxia 38 (SCA38) [MIM:615957]: A form of spinocerebellar ataxia, a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA38 is an autosomal dominant form characterized by adult-onset of slowly progressive gait ataxia accompanied by nystagmus. Brain MRI shows cerebellar atrophy. {ECO:0000269 PubMed:25065913}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for ELOVL5

Genetic Association Database (GAD)
ELOVL5
Human Genome Epidemiology (HuGE) Navigator
ELOVL5
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ELOVL5
genes like me logo Genes that share disorders with ELOVL5: view

No data available for Genatlas for ELOVL5 Gene

Publications for ELOVL5 Gene

  1. ELOVL5 mutations cause spinocerebellar ataxia 38. (PMID: 25065913) Di Gregorio E … Brusco A (American journal of human genetics 2014) 2 3 4 60
  2. Cloning of a human cDNA encoding a novel enzyme involved in the elongation of long-chain polyunsaturated fatty acids. (PMID: 10970790) Leonard AE … Mukerji P (The Biochemical journal 2000) 2 3 4 60
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 45 60
  4. ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis. (PMID: 20937905) Ohno Y … Kihara A (Proceedings of the National Academy of Sciences of the United States of America 2010) 3 4 60
  5. Genome-wide association study of normal tension glaucoma: common variants in SRBD1 and ELOVL5 contribute to disease susceptibility. (PMID: 20363506) Writing Committee for the Normal Tension Glaucoma Genetic Study Group of Japan Glaucoma Society … Bahram S (Ophthalmology 2010) 3 45 60

Products for ELOVL5 Gene

Sources for ELOVL5 Gene

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