Aliases for ELOVL2 Gene
- ELOVL Fatty Acid Elongase 2 2 3 4 5
- Elongation Of Very Long Chain Fatty Acids (FEN1/Elo2, SUR4/Elo3, Yeast)-Like 2 2 3
- Very Long Chain 3-Ketoacyl-CoA Synthase 2 3 4
- Very Long Chain 3-Oxoacyl-CoA Synthase 2 3 4
- 3-Keto Acyl-CoA Synthase ELOVL2 3 4
- ELOVL FA Elongase 2 3 4
- SSC2 3 4
- Elongation Of Very Long Chain Fatty Acids Protein 2 3
- EC 188.8.131.52 4
External Ids for ELOVL2 Gene
Previous GeneCards Identifiers for ELOVL2 Gene
GeneCards Summary for ELOVL2 Gene
ELOVL2 (ELOVL Fatty Acid Elongase 2) is a Protein Coding gene. Diseases associated with ELOVL2 include Malignant Melanoma, Somatic. Among its related pathways are Fatty acid elongation and Metabolism. GO annotations related to this gene include transferase activity, transferring acyl groups other than amino-acyl groups and fatty acid elongase activity. An important paralog of this gene is ELOVL5.
UniProtKB/Swiss-Prot for ELOVL2 Gene
Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate in the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.