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ELL Gene

protein-coding GIFtS: 62

GC19M018416

elongation factor RNA polymerase II
(Previous name: chromosome 19 open reading frame 17 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: C19orf17)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
C19orf17 ^², ³
DKFZp434I1916 ^²
ELL1 ^¹, ²
MEN ^²
Men ^¹

Descriptions
ELL gene (11-19 lysine-rich leukemia gene) ^²
Eleven-nineteen lysine-rich leukemia protein ^³
chromosome 19 open reading frame 17 ^¹
eleven-nineteen lysine-rich leukemia ^²
elongation factor RNA polymerase II ^²

External Ids
HGNC: 23114¹
Entrez Gene: 8178²
UniProtKB: P55199³
Ensembl: ENSG00000105656⁷

Search outside databases for aliases for ELL gene

Previous GC identifers: GC19M019048 GC19M018947 GC19M018399 GC19M018415

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ELL_HUMAN, P55199

Function: Elongation factor that can increase the catalytic rate of RNA polymerase II transcription

by suppressing transient pausing by the polymerase at multiple sites along the DNA

Gene Wiki entry for ELL

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ELL gene

Entrez Gene cytogenetic band: 19p13.1 Ensembl cytogenetic band: 19p13.11 HGNC cytogenetic band: 19p13.1

ELL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19M018416: (about GC identifiers)

Start:	18,414,473 bp from pter
End:	18,493,918 bp from pter
Size:	79,446 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000019.8 NT_011295.10

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: ELL_HUMAN, P55199 (See protein sequence)

Recommended Name: RNA polymerase II elongation factor ELL

Size: 621 amino acids; 68265 Da

Subunit: Interacts with EAF1 and EAF2

Subcellular location: Nucleus speckle. Nucleus, Cajal body. Note=Colocalizes with EAF2 to nuclear

speckles. Also localized to Cajal (coiled) bodies

PDB structures from and Proteopedia :

2DOA (3D)

Post-translational modifications:

Phosphorylated upon DNA damage, probably by ATM or ATR¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_006523.1

ENSEMBL proteins:

ENSP00000262809 ENSP00000376196

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (ELL)
	Human Recombinant Proteins from Abnova (ELL)

OriGene Purified Recombinant Human Protein: ELL

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--
GO:0005654	nucleoplasm	EXP	12676794
GO:0016607	nuclear speck	IEA	--

About this table

Antibodies for ELL:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for ELL
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (ELL), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (ELL)
	Novus Biologicals Antibodies for ELL

Assays for ELL:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P55199

ProtoNet protein and cluster: P55199

1 Blocks protein family: IPB010844 Occludin and RNA polymerase II elongation factor ELL

UniProtKB/Swiss-Prot: ELL_HUMAN, P55199

Similarity: Belongs to the ELL/occludin family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ELL)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ELL)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_006532

Applied Biosystems Silencer® siRNAs for ELL

Sigma-Aldrich siRNA for ELL

Sigma-Aldrich shRNA for ELL

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for ELL
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_006532
Myc/DDK tagged cDNA clone in CMV expression vector: NM_006532
untagged cDNA clones in CMV expression vector (see all 2): BC010010

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_006532

UniProtKB/Swiss-Prot: ELL_HUMAN, P55199

Function: Elongation factor that can increase the catalytic rate of RNA polymerase II transcription

by suppressing transient pausing by the polymerase at multiple sites along the DNA

Genatlas biochemistry entry for ELL:

eleven-nineteen lysine-rich leukemia gene,fused with HRX(MLL) in t(11;19) acute lymphoblastic

leukemia

1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Ell):

lethality-prenatal/perinatal

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	17395368
GO:0008159	positive transcription elongation factor activity	TAS	8596958

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for ELL

5/53 Interacting proteins for ELL (ENSP00000262809³ P55199¹) via UniProtKB, MINT, and/or STRING (see all 53 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TFPT	P0C1Z6¹	EBI-1245868, EBI-1245626
SNF8	ENSP00000290330³	STRING (score=.995)
EAF2	ENSP00000273668³	STRING (score=.978)
POLR2A	ENSP00000314949³	STRING (score=.975)
CDK9	ENSP00000362362³	STRING (score=.951)

About this table

3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006350	transcription	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	IEA	--
GO:0006368	RNA elongation from RNA polymerase II promoter	TAS	8596958

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for ELL

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ELL)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ELL)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_006532

Sigma-Aldrich siRNA for ELL

Sigma-Aldrich shRNA for ELL

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_006532

REFSEQ mRNAs for ELL gene:

NM_006532.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_006532

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_006532
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_006532
                                 untagged cDNA clones in CMV expression vector (see all 2): BC010010

Additional cDNA sequence:

AB208794.1 AF157562.1 AK225481.1 AK293105.1 AK309878.1 AL136771.1 BC010010.2 BC033673.1

BC049195.1 BC064558.1 BC108256.1 CR606202.1 S77880.1 S77889.1 U16282.1

8 DOTS entries:

DT.100746195 DT.411268 DT.100739993 DT.121456731 DT.97841700 DT.91681518 DT.91731190 DT.75102546

24/166 AceView cDNA sequences (see all 166 ):

F11595 CA434042 NM_006532 BC064558 AI676084 BX100377 BE326983 CF131209

U16282 AL118983 BM680583 CF593337 BX417969 BM806318 BE514345 CR606202

BE293594 BF593292 BC049195 BQ008204 AL543671 BE293597 BM553152 BC033673

highest scoring ESTs for ELL:

U16282 AI830319 AL118983 AL543671 AL557978 AL570404 BC049195 BE242864 BE514345 BF898251

Unigene Cluster for ELL:

Elongation factor RNA polymerase II

Hs.515260 [show with all ESTs]

Unigene Representative Sequence: NM_006532

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for ELL

ExUns:	1a	·	1b	^	2	^	3a	·	3b	^	4	^	5	^	6	^	7	^	8	^	9	^	10a	·	10b	^	11	^	12a	·	12b	^	13	^	14a	·	14b	·	14c
SP1:					-				-																						-
SP2:					-				-		-																				-
SP3:									-		-																				-
SP4:
SP5:					-

About this scheme

ECgene alternative splicing isoforms for ELL

2 Ensembl transcripts including schematic representations:

ENST00000262809 ENST00000392395

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

ELL expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ELL

¹ / ² / ³

7 probe-sets matching ELL gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
62568_at²^{, 3}	U95-C	1	1.00	1.00	0.91	1.18	AI830319	0.80	1.00	0.91	1
40044_at²^{, 3}	U95-A	1	1.00	1.00	0.81	0.82	U16282	1.00	1.00	1.00	1
204095_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AL521391	0.60	1.00	0.82	1
204096_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AL136771	0.60	1.00	0.82	1
204095_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
1565254_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
204096_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks ELL for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GGGTTGGTGT

SOURCE GeneReport for Unigene cluster: Hs.515260
Expression variation in blood from EXPOLDB for ELL
UniProtKB/Swiss-Prot: ELL_HUMAN, P55199
Tissue specificity: Expressed in all tissues tested. Highest levels found in placenta, skeletal
muscle, testis and peripheral blood leukocytes

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ELL gene from 5/9 species (see all 9 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	ELL¹	--	elongation factor RNA polymerase II	86.13(n) 89.89(a)	484820 XM_541936.2 XP_541936.2
cow (Bos taurus)	ELL¹	--	elongation factor RNA polymerase II	87.93(n) 88.96(a)	506578 XM_583044.3 XP_583044.2
rat (Rattus norvegicus)	Ell¹	--	elongation factor RNA polymerase II	80.49(n) 84.41(a)	306347 XM_224727.4 XP_224727.4
mouse (Mus musculus)	Ell^{1, 5}	8⁵	elongation factor RNA polymerase II^{1, 5}	80.7(n)¹ 84.19(a)¹	13716¹ NM_007924.2¹ NP_031950.2¹ AA175554⁵ AK159027⁵ (see all 15)
chicken (Gallus gallus)	ELL¹	--	elongation factor RNA polymerase II	72.61(n) 73.5(a)	420124 NM_001012847.1 NP_001012865.1

About this table Species with no ortholog for ELL

ENSEMBL Gene Tree for ELL

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for ELL gene

ELL3² ELL2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/392 NCBI SNPs in ELL are shown (see all 392 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 124)

AB	SNP ID	Valid	Chr 19 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs1043327^1,2	C,F,H	18415972(-)	`CTCCTT/CGGGCA`	1	--	ut3¹ trp³		8		MN NA EU EA WA	738
--	rs7252130^1,2	A,C	18494436(+)	`AAACGA/GAGCGC`	1	--	ng3¹		0	--	--	--	--
--	rs172032^1,2	A,C	18494755(+)	`ctgggC/Tctgct`	1	--	ng3¹		0	--	--	--	--
	rs2303694^1,2	C,F	18423438(+)	`CAGTGC/TTCTGT`	1	S/N	mis¹ ese³		5		NA EU EA WA	490
	rs35245196^1,2	C,F	18422593(+)	`CAGCCG/ACGGGG`	1	W/R	mis¹		5		NA EU EA WA	490
--	rs35568470^1,2	F	18415207(+)	`CAACA-/CATCTGT`	1	--	ut3¹		5		EU EA NA MN	430
	rs35328461^1,2	F	18433616(+)	`GGCACC/AGCGTC`	1	A/A	syn¹		1		NA	74
	rs2013069^1,2	A,C,F,H,O	18460757(-)	`AGGACT/ACTGGT`	1	--	int¹		8		EU EA WA NA	630
	rs875396^1,2	A,C,F,H,O	18472147(-)	`CATGGT/CCACAC`	1	--	int¹		10		NA EA EU WA	792
	rs1971093^1,2	A,C,F,H,O	18448157(-)	`CCTCAG/CCATCA`	1	--	int¹		7		NA EU EA WA	554

About this table

HapMap Linkage Disequilibrium images for ELL (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 600284

UniProtKB/Swiss-Prot: ELL_HUMAN, P55199

A chromosomal translocation involving ELL is found in acute leukemias. Translocation

t(11;19)(q23;p13.1) with MLL/HRX. The result is a rogue activator protein

5 Novoseek disease relationships for ELL gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
myeloid leukemia	67.58	2	9478981 (1)
acute leukemia	31.79	2	15650021 (1)
leukemia	17.43	6	15650021 (1), 11520560 (1)
shock	2.66	2	15611125 (2)
tumors	0.00	1	10765922 (1)

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Human Gene Mutation Database: ELL

(Possibly Related Articles in Doctor's Guide)
About This Section

European Advisory Panel Backs Myocet (Liposome Encapsulated Doxorubicin Citrate Complex) For Breast Cancer

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/48 PubMed articles for ELL gene (see all 48 ):

An RNA polymerase II elongation factor encoded by the human ELL gene. (PubMed id 8596958)^{1, 2, 3, 4} Shilatifard A....Conaway J.W. (1996)
Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia. (PubMed id 7991593)^{2, 3, 4} Thirman M.J.... Rowley J.D. (1994)
ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL. (PubMed id 16006523)^{1, 3, 4} Kong S.E.... Conaway R.C. (2005)
ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties. (PubMed id 12446457)^{1, 3, 4} Simone F.... Thirman M.J. (2003)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
ELL and EAF1 are Cajal body components that are disrupted in MLL-ELL leukemia. (PubMed id 12686606)^{3, 4} Polak P.E.... Thirman M.J. (2003)
EAF1, a novel ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein. (PubMed id 11418481)^{3, 4} Simone F....Thirman M.J. (2001)
Structure and function of RNA polymerase II elongation factor ELL. Identification of two overlapping ELL functional domains that govern its interaction with polymerase and the ternary elongation complex. (PubMed id 9268387)^{1, 3} Shilatifard A....Conaway J.W. (1997)
Identification and purification of the Holo-ELL complex. Evidence for the presence of ELL-associated proteins that suppress the transcriptional inhibitory activity of ELL. (PubMed id 9556611)^{1, 3} Shilatifard A. (1998)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)⁴ Dephoure N.... Gygi S.P. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 8178	HGNC: 23114	AceView: ELL	Ensembl:ENSG00000105656	euGenes: HUgn8178
ECgene: ELL	H-InvDB: ELL

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for ELL	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for ELL
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for ELL:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ELL-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ELL		Antibodies for ELL
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ELL		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (ELL)
	Antibodies (ELL)
	Chimera RNAi (ELL)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (ELL)
	Antibodies (ELL)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for ELL

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for ELL

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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ELL Gene

protein-coding GIFtS: 62

Aliases &
Descriptions
for ELL

Summaries
for ELL

Genomic Location
for ELL

Proteins
for ELL

Protein Domains/
Families
for ELL

Gene Function
for ELL

Pathways & Interactions
for ELL

Drugs & Compounds
for ELL

Transcripts
for ELL

Expression
for ELL

Orthologs
for ELL

Paralogs
for ELL

SNPs/Variants
for ELL

Disorders & Mutations
for ELL

Medical News
for ELL

Publications
for ELL

Search for ELL

Genome Databases showing ELL

Other Databases showing ELL

Specialized Databases showing ELL

Licensable Technologies
for ELL

Services
for ELL

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ELL Gene

protein-coding GIFtS: 62

Aliases & Descriptionsfor ELL

Summariesfor ELL

Genomic Locationfor ELL

Proteinsfor ELL

Protein Domains/Familiesfor ELL

Gene Functionfor ELL

Pathways & Interactionsfor ELL

Drugs & Compoundsfor ELL

Transcriptsfor ELL

Expression for ELL

Orthologsfor ELL

Paralogsfor ELL

SNPs/Variantsfor ELL

Disorders & Mutationsfor ELL

Medical Newsfor ELL

Publicationsfor ELL

Search for ELL

Genome Databases showing ELL

Other Databases showing ELL

Specialized Databases showing ELL

Licensable Technologiesfor ELL

Servicesfor ELL

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ELL

Summaries
for ELL

Genomic Location
for ELL

Proteins
for ELL

Protein Domains/
Families
for ELL

Gene Function
for ELL

Pathways & Interactions
for ELL

Drugs & Compounds
for ELL

Transcripts
for ELL

Expression
for ELL

Orthologs
for ELL

Paralogs
for ELL

SNPs/Variants
for ELL

Disorders & Mutations
for ELL

Medical News
for ELL

Publications
for ELL

Licensable Technologies
for ELL

Services
for ELL