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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ELK4 Gene

protein-coding   GIFtS: 54
GCID: GC01M205577

ELK4, ETS-domain protein (SRF accessory protein 1)

 Explore 3 diseases affiliated with
ELK4 via our new
 Human Malady Compendium 
Biological research products
for ELK4
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
ELK4, ETS-Domain Protein (SRF Accessory Protein 1)1 2
SAP11 2 3 5
Serum Response Factor Accessory Protein 12 3
SAP-12 3
ETS Domain-Containing Protein Elk-42
SRF Accessory Protein 13

External Ids:    HGNC: 33261   Entrez Gene: 20052   Ensembl: ENSG000001587117   OMIM: 6002465   UniProtKB: P283243   

Export aliases for ELK4 gene to outside databases

Previous GC identifers: GC01M203506 GC01M201046 GC01M201927 GC01M202744 GC01M202762 GC01M202298 GC01M203833 GC01M203851 GC01M176751


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ELK4:
This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily.
Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse
element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is phosphorylated by the
kinases, MAPK1 and MAPK8. Several transcript variants have been described for this gene. (provided by RefSeq, Jul
2008)

UniProtKB/Swiss-Prot: ELK4_HUMAN, P28324
Function: Involved in both transcriptional activation and repression. Interaction with SIRT7 leads to recruitment and
stabilization of SIRT7 at promoters, followed by deacetylation of histone H3 at 'Lys-18' (H3K18Ac) and subsequent
transcription repression. Forms a ternary complex with the serum response factor (SRF). Requires DNA-bound SRF for
ternary complex formation and makes extensive DNA contacts to the 5'side of SRF, but does not bind DNA autonomously

Gene Wiki entry for ELK4


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ELK4 gene promoter:
         p53   FOXF2   GATA-1   S8   POU2F1   FOXO4   POU2F1b   POU2F1a   POU2F1c   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ELK4 promoter sequence
   Search SABiosciences Chromatin IP Primers for ELK4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ELK4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32   Ensembl cytogenetic band:  1q32.1   HGNC cytogenetic band: 1q32

ELK4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ELK4 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M205577:  view genomic region     (about GC identifiers)

Start:
205,577,071 bp from pter      End:
205,602,000 bp from pter
Size:
24,930 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ELK4_HUMAN, P28324 (See protein sequence)
Recommended Name: ETS domain-containing protein Elk-4  
Size: 431 amino acids; 46900 Da
Subunit: Interacts with SIRT7
Subcellular location: Nucleus
4 PDB 3D structures from and Proteopedia for ELK4:
1BC7 (3D)        1BC8 (3D)        1HBX (3D)        1K6O (3D)    
Secondary accessions: P28323 Q6GSJ2
Alternative splicing: 2 isoforms:  P28324-1   P28324-2   

Explore the universe of human proteins at neXtProt for ELK4: NX_P28324

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P28324

  • ELK4 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001964.2  NP_068567.1  

    ENSEMBL proteins: 
     ENSP00000350681   ENSP00000289703  

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    Uscn Proteins for ELK4

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--


    ELK4 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for ELK4


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ELK4 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR011991 WHTH_trsnscrt_rep_DNA-bd_dom
     IPR000418 Ets_dom

    Graphical View of Domain Structure for InterPro Entry P28324

    ProtoNet protein and cluster: P28324

    UniProtKB/Swiss-Prot: ELK4_HUMAN, P28324
    Similarity: Belongs to the ETS family
    Similarity: Contains 1 ETS DNA-binding domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: ELK4_HUMAN, P28324
    Function: Involved in both transcriptional activation and repression. Interaction with SIRT7 leads to recruitment and
    stabilization of SIRT7 at promoters, followed by deacetylation of histone H3 at 'Lys-18' (H3K18Ac) and subsequent
    transcription repression. Forms a ternary complex with the serum response factor (SRF). Requires DNA-bound SRF for
    ternary complex formation and makes extensive DNA contacts to the 5'side of SRF, but does not bind DNA autonomously

         Genatlas biochemistry entry for ELK4:
    ets related protooncogene 4,homologous to murine Sap1,ubiquitously expressed,associating with a ternary complex factor
    1 and SRF transcription factor and recruited to the c-fos serum response element,divergent member of the winged
    helix-turn-helix superfamily

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    hsa-miR-124* hsa-miR-520f hsa-miR-106a hsa-miR-1260b hsa-miR-519a hsa-miR-3622b-3p hsa-miR-200b hsa-miR-92b
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    Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001047core promoter binding TAS--
    GO:0003677DNA binding TAS1339307
    GO:0003682chromatin binding IDA--
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0003712transcription cofactor activity TAS7851904


    ELK4 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Elk4tm1Rtr for ELK4
         9 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Elk4):
     behavior/neurological  cellular  growth/size  hematopoietic system  homeostasis/metabolism 
     immune system  other  skeleton  vision/eye 

    ELK4 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/14 super-pathways (see all 14About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Signal transduction_JNK pathway
    Signal transduction_JNK pathway1.00
    Signal transduction JNK pathway0.98
    2Apoptotic Pathways in Synovial Fibroblasts
    ERK5 Signaling0.61
    Rac1 Pathway0.58
    3Rho Family GTPases
    ERK Signaling0.61
    Molecular Mechanisms of Cancer0.51
    4Development_CNTF receptor signaling
    Development_Growth hormone signaling via PI3K/AKT and MAPK cascades0.34
    Development Growth hormone signaling via PI3K/AKT and MAPK cascades0.34
    5TRKA Signaling
    TRKA Signaling1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    2 EMD Millipore Pathways for ELK4
        Development Growth hormone signaling via PI3K/AKT and MAPK cascades
    Signal transduction JNK pathway

    5/8 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for ELK4 (see all 8)
        FLT3 Signaling
    Rac1 Pathway
    ERK Signaling
    Molecular Mechanisms of Cancer
    TRKA Signaling

    2 GeneGo (Thomson Reuters) Pathways for ELK4
        Signal transduction JNK pathway
    Development Growth hormone signaling via PI3K/AKT and MAPK cascades

    5 BioSystems Pathways for ELK4 
        Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
    Serotonin Receptor 4/6/7 and NR3C Signaling
    EGFR1 Signaling Pathway
    Id Signaling Pathway
    Signaling mediated by p38-alpha and p38-beta


    1         Kegg Pathway  (Kegg details for ELK4):
        MAPK signaling pathway


    ELK4 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ELK4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

    5/16 Interacting proteins for ELK4 (P283243 ENSP000003506814) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SRFP118313, ENSP000002653544I2D: score=3 STRING: ENSP00000265354
    MAPK11Q157593, ENSP000003336854I2D: score=2 STRING: ENSP00000333685
    MAPK3P273613, ENSP000002630254I2D: score=2 STRING: ENSP00000263025
    BRCA1P383983, ENSP000003502834I2D: score=1 STRING: ENSP00000350283
    ID3Q025353, ENSP000003636894I2D: score=1 STRING: ENSP00000363689
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IMP--
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0070932histone H3 deacetylation IDA--


    ELK4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ELK4
    Search CenterWatch for drugs/clinical trials and news about ELK4 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ELK4 gene (2 alternative transcripts): 
    NM_001973.3  NM_021795.2  

    Unigene Cluster for ELK4:

    ELK4, ETS-domain protein (SRF accessory protein 1)
    Hs.497520  [show with all ESTs]
    Unigene Representative Sequence: NM_001973
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000357992(uc021pid.1 uc001hcy.2) ENST00000289703(uc001hcz.3)
    ENST00000468523(uc010prq.1)

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    8/132 QIAGEN miScript miRNA Assays for microRNAs that regulate ELK4 (see all 132):
    hsa-miR-124* hsa-miR-520f hsa-miR-106a hsa-miR-1260b hsa-miR-519a hsa-miR-3622b-3p hsa-miR-200b hsa-miR-92b
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    Inhib. RNA
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    Additional cDNA sequence: 

    AF075044.1 AK024944.1 AL117645.1 BC063676.1 M85164.1 M85165.1 

    10 DOTS entries:

    DT.97838796  DT.92423912  DT.112518  DT.97819121  DT.40298893  DT.92423913  DT.100751161  DT.91773250 
    DT.100799986  DT.100848809 

    24/81 AceView cDNA sequences (see all 81):

    AA970359 AW945159 CK821104 AW150970 BI793265 BM458403 BC040145 BI792972 
    BC063676 NM_021795 CR623173 T27937 NM_001973 CK821103 AW950095 BE676052 
    BG290746 M85164 BX346360 AA230039 AW612508 BE675475 AI689765 AA228919 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ELK4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TAACCAAAAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See ELK4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ELK4

    SOURCE GeneReport for Unigene cluster: Hs.497520
        SABiosciences Expression via Pathway-Focused PCR Array including ELK4: 
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ELK4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ELK4 gene from 5/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves ELK41 ELK4, ETS-domain protein (SRF accessory protein 1) 75.66(n)
    79.07(a)
      419832  XM_417965.2  XP_417965.2 
    lizard
    (Anolis carolinensis)
    Reptilia ELK46
    --
    70(a)
    1 ↔ 1
    GL343228.1(396439-403160)
    African clawed frog
    (Xenopus laevis)
    Amphibia elk4-A2 ELK4, ETS-domain protein (SRF accessory protein 1) 79.54(n)    AY029410.1 
    zebrafish
    (Danio rerio)
    Actinopterygii elk42 ELK4, ETS-domain protein 75.68(n)   30093  AJ249170.1 
    worm
    (Caenorhabditis elegans)
    Secernentea ets-86
    ets-76
    (see all 4)
    Protein ETS-7
    (see all 4)
    18(a)
    17(a)
    (see all 4)
    possible ortholog
    possible ortholog
    (see all 4)
    IV(1159637-1161545)
    V(7557738-7558764)


    ENSEMBL Gene Tree for ELK4 (if available)
    TreeFam Gene Tree for ELK4 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ELK4 gene
    ETV12  ETV32  ERF2  ETV52  ETV3L2  ETS12  GABPA2  ETS22  
    ERG2  ELK12  FEV2  ETV42  ETV22  FLI12  ELK32  
    2 SIMAP similar genes for ELK4 using alignment to 1 protein entry:     ELK4_HUMAN:
    ELF5    ELK3

    ELK4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/490 NCBI SNPs in ELK4 are shown (see all 490    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1846621911,2
    --205576587(+) CCCCAC/GCACGT 1 -- ds50010--------
    rs1891797671,2
    --205576728(+) CACTGC/TACCCA 1 -- ds50010--------
    rs1407590681,2
    --205576777(+) AAACAA/GAAAGA 1 -- ds50010--------
    rs28678921,2
    C,A,--205576917(+) TACATA/GTCAAA 1 -- ds50018Minor allele frequency- G:0.29NA EA WA 722
    rs1113410641,2
    --205576921(+) TATCAG/AATTGT 1 -- ds50011Minor allele frequency- A:0.50CSA 2
    rs1454747371,2
    --205577082(+) TGTTAA/CAAATA 1 -- ut310--------
    rs1822231791,2
    --205577263(+) AATGTA/GTATCT 1 -- ut310--------
    rs1872374471,2
    --205577317(+) TTTGCA/GTAAAA 1 -- ut310--------
    rs1888268591,2
    --205577413(+) CATTTA/TTTTTT 1 -- ut310--------
    rs1402252001,2
    --205577430(+) AGCATA/TTTATT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for ELK4 (205577071 - 205602000 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for ELK4: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ELK4 for disorders           About GeneDecksing

    OMIM gene information: 600246    OMIM disorders: --

    3 diseases for ELK4:    About MalaCards
    prostate cancer    breast cancer    prostatitis


    Export disorders for ELK4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ELK4 gene, integrated from 9 sources (see all 46):
    (articles sorted by number of sources associating them with ELK4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mapping of the human SAP1 (SRF accessory protein 1) gene and SAP2, a gene encoding a related protein, to chromosomal bands 1q32 and 12q23, respectively. (PubMed id 7851904)1, 3, 9 Shipley J....Patel K. (1994)
    2. Structures of SAP-1 bound to DNA targets from the E74 and c-fos promoters: insights into DNA sequence discrimination by Ets proteins. (PubMed id 9734357)1, 2, 9 Mo Y.... Marmorstein R. (1998)
    3. Locations of the ets subfamily members net, elk1, and sap1 (ELK3, ELK1, and ELK4) on three homologous regions of the mouse and human genomes. (PubMed id 8575773)1, 3 Giovane A....Wasylyk B. (1995)
    4. Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element. (PubMed id 8293474)1, 2 Dalton S. and Treisman R. (1994)
    5. Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element. (PubMed id 1339307)1, 2 Dalton S. and Treisman R. (1992)
    6. Crystal structure of a ternary SAP-1/SRF/c-fos SRE DNA complex. (PubMed id 11846562)1, 9 Mo Y....Marmorstein R. (2001)
    7. c-Fos oncogene regulator Elk-1 interacts with BRCA1 splice variants BRCA1a/1b and enhances BRCA1a/1b-mediated growth suppression in breast cancer cells. (PubMed id 11313879)1, 9 Chai Y....Rao V.N. (2001)
    8. Identification of ETS-like transcription factor 4 as a novel androgen receptor target in prostate cancer cells. (PubMed id 18469865)1, 9 Makkonen H....Palvimo J.J. (2008)
    9. Comparative analysis of the ternary complex factors Elk-1, SAP-1a and SAP-2 (ERP/NET). (PubMed id 7540136)1, 9 Price M.A.... Treisman R. (1995)
    10. Chimeric transcript generated by cis-splicing of adjac ent genes regulates prostate cancer cell proliferation. (PubMed id 22719019)1 Zhang Y....Li H. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2005 HGNC: 3326 AceView: ELK4 Ensembl:ENSG00000158711 euGenes: HUgn2005
    ECgene: ELK4 Kegg: 2005 H-InvDB: ELK4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ELK4 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ELK4 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ELK4 gene:
    Search GeneIP for patents involving ELK4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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