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ELK3 Gene

protein-coding GIFtS: 60

GC12P095090

ELK3, ETS-domain protein (SRF accessory protein 2)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
ERP ^¹, ², ⁵
NET ^¹, ², ³
SAP-2 ^³
SAP2 ^¹, ², ³, ⁵

Descriptions
ELK3 protein ^²
ELK3, ETS-domain protein (SRF accessory protein 2) ^²
ETS-domain protein ^²
ETS-related protein ERP ^³
ETS-related protein NET ^³
SRF accessory protein 2 ^², ³

External Ids
HGNC: 3325¹
Entrez Gene: 2004²
UniProtKB: P41970³
Ensembl: ENSG00000111145⁷

Search outside databases for aliases for ELK3 gene

Previous GC identifers: GC12P096023 GC12P096951 GC12P096521

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for ELK3:

The protein encoded by this gene is a member of the ETS-domain transcription factor family and the

ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when

recruited by serum response factor to bind to serum response elements. This protein is activated

by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional

inhibitor in the absence of Ras, but activates transcription when Ras is present. [provided by

RefSeq]

UniProtKB/Swiss-Prot: ELK3_HUMAN, P41970

Function: May be a negative regulator of transcription, but can activate transcription when

coexpressed with Ras, Src or Mos. Forms a ternary complex with the serum response factor and the

ETS and SRF motifs of the Fos serum response element

Gene Wiki entry for ELK3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ELK3 gene

Entrez Gene cytogenetic band: 12q23 Ensembl cytogenetic band: 12q23.1 HGNC cytogenetic band: 12q23

ELK3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12P095090: (about GC identifiers)

Start:	95,112,338 bp from pter
End:	95,185,740 bp from pter
Size:	73,403 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000012.10 NT_019546.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: ELK3_HUMAN, P41970 (See protein sequence)

Recommended Name: ETS domain-containing protein Elk-3

Size: 407 amino acids; 44240 Da

Subunit: Interacts with CTBP1

Subcellular location: Nucleus

Secondary accessions: Q6FG57 Q6GU29 Q9UD17

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_005221.2

ENSEMBL proteins:

ENSP00000228741

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (ELK3)
	Human Recombinant Proteins from Abnova (ELK3)

OriGene Purified Recombinant Human Protein: ELK3

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IC	12933792
GO:0005730	NOT nucleolus	IDA	18029348
GO:0005739	mitochondrion	IDA	18029348

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Antibodies for ELK3:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for ELK3
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (ELK3), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (ELK3)
	Novus Biologicals Antibodies for ELK3

Assays for ELK3:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry P41970

ProtoNet protein and cluster: P41970

UniProtKB/Swiss-Prot: ELK3_HUMAN, P41970

Similarity: Belongs to the ETS family

Similarity: Contains 1 ETS DNA-binding domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ELK3)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ELK3)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005230

Applied Biosystems Silencer® siRNAs for ELK3

Sigma-Aldrich siRNA for ELK3

Sigma-Aldrich shRNA for ELK3

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for ELK3
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_005230
Myc/DDK tagged cDNA clone in CMV expression vector: NM_005230
untagged cDNA clone in CMV expression vector: NM_005230

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_005230

UniProtKB/Swiss-Prot: ELK3_HUMAN, P41970

Function: May be a negative regulator of transcription, but can activate transcription when

coexpressed with Ras, Src or Mos. Forms a ternary complex with the serum response factor and the

ETS and SRF motifs of the Fos serum response element

Genatlas biochemistry entry for ELK3:

ets related protooncogene 3,homologous to murine Net (Erp),ubiquitous but expressed primarily at

early stages of B-lymphocyte development with a drastic decline,upon B-cell maturation,activated

by RAS,divergent member of the winged helix-turn-helix superfamily

6 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Elk3):

	behavior/neurological	immune system	lethality-postnatal	life span-post-weaning/aging
respiratory system

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	transcription factor activity	NAS	7851904
GO:0003714	transcription corepressor activity	IDA	12933792
GO:0005515	protein binding	IPI	17474147
GO:0032422	purine-rich negative regulatory element binding	IDA	12933792

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

2 Sigma-Aldrich "Your Favorite Gene" Pathways for ELK3 (Your Favorite Gene powered by Ingenuity)

HGF Signaling
ERK/MAPK Signaling

GeneDecks ELK3 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for ELK3

5/6 Interacting proteins for ELK3 (P41970¹ ENSP00000228741³) via UniProtKB, MINT, and/or STRING (see all 6 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GRB2	P62993¹	EBI-1758534, EBI-401755
NCK1	P16333¹	EBI-1758534, EBI-389883
PIK3R1	P27986¹	EBI-1758534, EBI-79464
CFH	ENSP00000356399³	STRING (score=.951)
PLG	ENSP00000308938³	STRING (score=.846)

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5 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001525	angiogenesis	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	IEA	--
GO:0007165	signal transduction	TAS	7958835
GO:0016481	negative regulation of transcription	IDA	12933792
GO:0042060	wound healing	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Compounds for ELK3 available from Tocris Bioscience

Compound	Action	CAS number
XRP44X	Ras-Net pathway inhibitor	[729605-21-4]

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ELK3)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ELK3)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005230

Sigma-Aldrich siRNA for ELK3

Sigma-Aldrich shRNA for ELK3

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_005230

REFSEQ mRNAs for ELK3 gene:

NM_005230.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_005230

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_005230
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_005230
                                 untagged cDNA clone in CMV expression vector: NM_005230

Additional cDNA sequence:

AK026078.1 AK312694.1 BC017371.1 CR542251.1 Z36715.1

9 DOTS entries:

DT.317487 DT.99932846 DT.40124776 DT.100044669 DT.121214954 DT.40204463 DT.40272038 DT.91938037

DT.100791197

24/205 AceView cDNA sequences (see all 205 ):

AI754275 BQ448099 AA921966 AW303921 BM921503 AI499197 CA393990 AW295741

AA983721 CR542251 AI077590 AK026078 BI091429 AI682746 F10001 CB852715

AA599413 BU902349 BU683844 NM_005230 AA724402 AA344225 CA418141 AA557143

highest scoring ESTs for ELK3:

Z36715 AA029744 AA091123 AA262193 AA296894 AA577263 AA744497 AA912448 AI076964 AI077590

Unigene Cluster for ELK3:

ELK3, ETS-domain protein (SRF accessory protein 2)

Hs.46523 [show with all ESTs]

Unigene Representative Sequence: NM_005230

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for ELK3

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7a	·	7b	^	8	^	9	^	10	^	11a	·	11b	·	11c
SP1:					-		-		-												-
SP2:					-
SP3:							-		-
SP4:																					-
SP5:

About this scheme

ECgene alternative splicing isoforms for ELK3

1 Ensembl transcript including schematic representation:

ENST00000228741

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

ELK3 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ELK3

¹ / ² / ³

8 probe-sets matching ELK3 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
37527_at²^{, 3}	U95-A	1	0.94	1.00	0.93	0.68	Z36715	1.00	1.00	1.00	1
65708_at*²^{, 3}	U95-C	1	1.00	1.00	0.97	1.32	AA029744	0.80	1.00	0.91	1
206127_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_005230	0.60	1.00	0.82	1
221773_at*²^{, 3}	U133-A	1	1.00	1.00	--	--	AW575374	0.60	1.00	0.82	1
202015_x_at*²	U133-A	8	1.00	0.19	--	--	--	--	--	--	--
206127_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
221773_at*²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
202015_x_at*²	U133Plus2	8	1.00	0.19	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TGTGTGTTAG

SOURCE GeneReport for Unigene cluster: Hs.46523
Expression variation in blood from EXPOLDB for ELK3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ELK3 gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	ELK3¹	--	ELK3, ETS-domain protein (SRF accessory protein 2)	92.7(n) 95.27(a)	482613 XM_539730.2 XP_539730.2
chimpanzee (Pan troglodytes)	ELK3¹	--	ELK3, ETS-domain protein (SRF accessory protein 2)	99.59(n) 99.75(a)	467100 XM_001146216.1 XP_001146216.1
cow (Bos taurus)	ELK3¹	--	ELK3, ETS-domain protein (SRF accessory protein 2)	92.37(n) 96.02(a)	541125 XM_614669.3 XP_614669.2
rat (Rattus norvegicus)	Elk3¹	--	ELK3, member of ETS oncogene family	89.27(n) 93.37(a)	362871 XM_343198.3 XP_343199.3
mouse (Mus musculus)	Elk3^{1, 5}	10 (51.00 cM)⁵	ELK3, member of ETS oncogene family^{1, 5}	89.11(n)¹ 91.15(a)¹	13713¹ NM_013508.1¹ NP_038536.1¹ AK052546⁵ AK088129⁵ (see all 14)

About this table Species with no ortholog for ELK3

ENSEMBL Gene Tree for ELK3

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for ELK3 gene

SPDEF²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/373 NCBI SNPs in ELK3 are shown (see all 373 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 124)

AB	SNP ID	Valid	Chr 12 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs7132101^1,2	A,C,F,H	95110752(+)	`TGCCCA/GAAGGA`	1	--	ng5¹ tfbs³		3		EU EA	300
	rs11833332^1,2	C,F,H	95185895(+)	`CAAGAA/CTATCT`	1	--	ng3¹		4		EU EA WA	420
	rs11831643^1,2	C,F,H	95186169(+)	`CTTGCT/CGTAAT`	1	--	ng3¹		4		EU EA WA	408
	rs2302901^1,2	C,F,H	95185145(-)	`TAGCCC/TGTGGG`	1	--	ut3¹ ese³		13		EA NA EU WA	2548
--	rs6538704^1,2	A,C	95185832(+)	`AGATGC/TCTCCC`	1	--	ng3¹		0	--	--	--	--
--	rs35332676^1,2	C,F	95165147(+)	`GGAGCC/TGCCCG`	1	P/L	mis¹		5		NA EU EA WA	498
	rs1063999^1,2	H	95165095(+)	`CCCTGC/GAGAAC`	1	Q/E	mis¹ ese³		5		MN EU EA WA	580
	rs12308094^1,2	H	95185408(+)	`TGTGAA/TGCTTT`	1	--	ut3¹		4		EU EA WA	390
	rs2887095^1,2	A,C,F,H,O	95126351(+)	`AGTTCC/GCAGTT`	1	--	int¹		7		EA WA NA	512
	rs2268500^1,2	A,C,F,H,O	95181622(-)	`TCGATT/CGAAAT`	1	--	int¹		17		EA EU WA NA	2956

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HapMap Linkage Disequilibrium images for ELK3 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 600247

1 PharmGKB disease relationship for ELK3 gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Leukemia, Lymphocytic, Acute, L1	FA GN	12730115

About this table

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/26 PubMed articles for ELK3 gene (see all 26 ):

Comparative analysis of the ternary complex factors Elk-1, SAP-1a and SAP-2 (ERP/NET). (PubMed id 7540136)^{1, 3, 4} Price M.A.... Treisman R. (1995)
Mapping of the human SAP1 (SRF accessory protein 1) gene and SAP2, a gene encoding a related protein, to chromosomal bands 1q32 and 12q23, respectively. (PubMed id 7851904)^{1, 2, 3} Shipley J....Patel K. (1994)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Large-scale characterization of HeLa cell nuclear phosphoproteins. (PubMed id 15302935)^{3, 4} Beausoleil S.A....Gygi S.P. (2004)
Net, a new ets transcription factor that is activated by Ras. (PubMed id 7958835)^{3, 4} Giovane A.... Wasylyk B. (1994)
Net (ERP/SAP2) one of the Ras-inducible TCFs, has a novel inhibitory domain with resemblance to the helix-loop-helix motif. (PubMed id 8918463)^{1, 3} Maira S.M....Wasylyk B. (1996)
Growth inhibitory effect of the ternary complex factor Net on human pancreatic carcinoma cell lines. (PubMed id 18832796)³ Li B....Zhang Y. (2008)
Inhibition of the Ras-Net (Elk-3) pathway by a novel pyrazole that affects microtubules. (PubMed id 18316589)³ Wasylyk C....Wasylyk B. (2008)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)³ Barbe L....Andersson-Svahn H. (2008)
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)⁴ Daub H.... Mann M. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 2004	HGNC: 3325	AceView: ELK3	Ensembl:ENSG00000111145	euGenes: HUgn2004
ECgene: ELK3	H-InvDB: ELK3

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
ATLAS Chromosomes in Cancer entry for ELK3	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for ELK3
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for ELK3:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ELK3-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ELK3		Antibodies for ELK3
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ELK3		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
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	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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Tocris compounds for ELK3

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for ELK3

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ELK3 Gene

protein-coding GIFtS: 60

Aliases &
Descriptions
for ELK3

Summaries
for ELK3

Genomic Location
for ELK3

Proteins
for ELK3

Protein Domains/
Families
for ELK3

Gene Function
for ELK3

Pathways & Interactions
for ELK3

Drugs & Compounds
for ELK3

Transcripts
for ELK3

Expression
for ELK3

Orthologs
for ELK3

Paralogs
for ELK3

SNPs/Variants
for ELK3

Disorders & Mutations
for ELK3

Medical News
for ELK3

Publications
for ELK3

Search for ELK3

Genome Databases showing ELK3

Other Databases showing ELK3

Specialized Databases showing ELK3

Licensable Technologies
for ELK3

Services
for ELK3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ELK3 Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor ELK3

Summariesfor ELK3

Genomic Locationfor ELK3

Proteinsfor ELK3

Protein Domains/Familiesfor ELK3

Gene Functionfor ELK3

Pathways & Interactionsfor ELK3

Drugs & Compoundsfor ELK3

Transcriptsfor ELK3

Expression for ELK3

Orthologsfor ELK3

Paralogsfor ELK3

SNPs/Variantsfor ELK3

Disorders & Mutationsfor ELK3

Medical Newsfor ELK3

Publicationsfor ELK3

Search for ELK3

Genome Databases showing ELK3

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ELK3

Summaries
for ELK3

Genomic Location
for ELK3

Proteins
for ELK3

Protein Domains/
Families
for ELK3

Gene Function
for ELK3

Pathways & Interactions
for ELK3

Drugs & Compounds
for ELK3

Transcripts
for ELK3

Expression
for ELK3

Orthologs
for ELK3

Paralogs
for ELK3

SNPs/Variants
for ELK3

Disorders & Mutations
for ELK3

Medical News
for ELK3

Publications
for ELK3

Licensable Technologies
for ELK3

Services
for ELK3