Aliases for ELAVL3 Gene
External Ids for ELAVL3 Gene
Previous GeneCards Identifiers for ELAVL3 Gene
A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for ELAVL3 Gene
ELAVL3 (ELAV Like Neuron-Specific RNA Binding Protein 3) is a Protein Coding gene. Diseases associated with ELAVL3 include encephalitis and limbic encephalitis. GO annotations related to this gene include nucleotide binding and AU-rich element binding. An important paralog of this gene is PABPC1.
UniProtKB/Swiss-Prot for ELAVL3 Gene
Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3 (By similarity). May be involved in neuronal differentiation and maintenance.