EIF4G3 Gene
protein-coding GIFtS: 63
GCID: GC01M021132
|
|
eukaryotic translation initiation factor 4 gamma, 3
| |
Aliases
for EIF4G3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Eukaryotic Translation Initiation Factor 4 Gamma, 31 2 | | EIF-4G 32 3 | | EIF4GII1 | | EIF4G 32 3 | | EIF-4-Gamma 32 3 | | Eukaryotic Translation Initiation Factor 4 Gamma 32 | | EIF-4-Gamma II2 3 | | |
Export aliases for EIF4G3 gene to outside databasesPrevious GC identifers: GC01M020703 GC01M020168 GC01M020278 GC01M020602 GC01M020878 GC01M021005 GC01M019378 |
Summaries
for EIF4G3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: IF4G3_HUMAN, O43432Function: Probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap,ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Thought to be afunctional homolog of EIF4G1
Gene Wiki entry for EIF4G3
|
Genomic Views
for EIF4G3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004610.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the EIF4G3 gene promoter:
Nkx3-1 SRF RP58 Nkx3-1 v4 AML1a SRF (504 AA) MyoD Nkx3-1 v1 Nkx3-1 v2 Nkx3-1 v3
Other transcription factors
Search SABiosciences Chromatin IP Primers for EIF4G3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat EIF4G3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p36.12 Ensembl cytogenetic band: 1p36.12 HGNC cytogenetic band: 1p36.12EIF4G3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M021132: view genomic region
(about GC identifiers)
Start:
|
21,132,972 bp from pter |
End:
|
21,503,377 bp from pter |
Size:
|
370,406 bases |
Orientation:
|
minus strand |
|
Proteins
for EIF4G3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: IF4G3_HUMAN, O43432 (See
protein sequence)Recommended Name: Eukaryotic translation initiation factor 4 gamma 3 Size: 1585 amino acids; 176652 Da
Subunit: Interacts with EIF4A, EIF4E, eIF3 and PABPC1. Part of a complex with EIF4E. eIF4F is a multi-subunit complex,the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A,EIF4E and EIF4G1/EIF4G3. EIF4G1/EIF4G3 interacts through its C-terminus with the serine/threonine kinases MKNK1, andwith MKNK2. Appears to act as a scaffold protein, holding these enzymes in place to phosphorylate eIF4E.Non-phosphorylated EIF4EBP1 competes with EIF4G1/EIFG3 to interact with EIF4E; insulin stimulated MAP-kinase (MAPK1and MAPK3) phosphorylation of EIF4EBP1 causes dissociation of the complex allowing EIF4G1/EIF4G3 to bind andconsequent initiation of translation. EIF4G1/EIF4G3 interacts with PABPC1 to bring about circularization of the mRNA(By similarity)
1 PDB 3D structure from  and Proteopedia  for EIF4G3:1HU3 (3D)
Secondary accessions: B9EGQ7 Q15597 Q5SWC3 Q8NEN1Alternative splicing: 3 isoforms: O43432-1 O43432-2 O43432-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for EIF4G3: NX_O43432
Post-translational modifications:
Following infection by certain enteroviruses, rhinoviruses and aphthoviruses, EIF4G1 is cleaved by the viral protease2A, or the leader protease in the case of aphthoviruses. This shuts down the capped cellular mRNA transcription1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O43432
EIF4G3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001185730.1 NP_001185731.1 NP_001185732.1 NP_003751.2
ENSEMBL proteins: ENSP00000264211 ENSP00000415717 ENSP00000364069 ENSP00000349386 ENSP00000395381 ENSP00000396083 ENSP00000383274 ENSP00000364071 ENSP00000364073 ENSP00000444693 ENSP00000442010 ENSP00000444401 ENSP00000364062 Reactome Protein details: O43432
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005829 | cytosol |
TAS | -- | | GO:0016281 | eukaryotic translation initiation factor 4F complex |
TAS | 9418880 |
EIF4G3 for ontologies About GeneDecksing
EIF4G3 Antibody Products:
Assay Products for EIF4G3: |
Protein
Domains /
Families
for EIF4G3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
EIF4G3 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O43432ProtoNet protein and cluster: O43432 2 Blocks protein families: IPB003307 eIF4-gamma/eIF5/eIF2-epsilon IPB003890 Initiation factor eIF-4 gamma
UniProtKB/Swiss-Prot: IF4G3_HUMAN, O43432Similarity: Belongs to the eukaryotic initiation factor 4G familySimilarity: Contains 5 HEAT repeatsSimilarity: Contains 1 MI domainSimilarity: Contains 1 MIF4G domainSimilarity: Contains 1 W2 domain |
Function
for EIF4G3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: IF4G3_HUMAN, O43432Function: Probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap,ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Thought to be afunctional homolog of EIF4G1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for EIF4G3 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for EIF4G3
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): EIF4G3 (NM_001198801) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for EIF4G3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat EIF4G3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EIF4G3 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
EIF4G3 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for EIF4G3:
Animal Models:
3 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Eif4g3):
EIF4G3 for phenotypes About GeneDecksing
|
Pathways & Interactions
for EIF4G3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/12 super-pathways (see all 12) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Development_CNTF receptor signaling | | | 2 | Translation_Translation regulation by Alpha-1 adrenergic receptors | | | 3 | Cytokine Signaling in Immune system | | | 4 | Translocation of Influenza A virus nonstructural protein 1 (NS1A) into the nucleus | | | 5 | Immune System | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 EMD Millipore Pathways for EIF4G3
4 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for EIF4G3
3  GeneGo (Thomson Reuters) Pathways for EIF4G3
1  BioSystems Pathway for EIF4G3
5 
Reactome Pathways for EIF4G3
2 
Kegg Pathways (Kegg details for EIF4G3):
EIF4G3 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for EIF4G3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/38 Interacting proteins for EIF4G3 (O434322, 3 ENSP000002642114) via UniProtKB, MINT, STRING, and/or I2D (see all 38)About this table
Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table
EIF4G3 for ontologies About GeneDecksing
|
Drugs & Compounds
for EIF4G3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for EIF4G3
Search CenterWatch for drugs/clinical trials and news about EIF4G3 / IF4G3
|
Transcripts
for EIF4G3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for EIF4G3 gene (4 alternative transcripts): NM_001198801.1 NM_001198802.1 NM_001198803.1 NM_003760.4 Unigene Cluster for EIF4G3: Eukaryotic translation initiation factor 4 gamma, 3 Hs.467084 [show with all ESTs]Unigene Representative Sequence: NM_00119880117 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000264211(uc010odi.2 uc010odj.2 uc009vpz.3 uc001bec.3)
ENST00000435383 ENST00000496705 ENST00000374933 ENST00000485722 ENST00000356916(uc001beg.3 uc010odk.2 uc001beh.3)
ENST00000438975 ENST00000411888 ENST00000476088 ENST00000463775 ENST00000400422(uc001bef.3 uc001bee.3)
ENST00000374935 ENST00000374937 ENST00000536266 ENST00000537738 ENST00000544689
ENST00000374927
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for EIF4G3 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for EIF4G3
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): EIF4G3 (NM_001198801) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for EIF4G3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat EIF4G3 |
Additional cDNA sequence: AB209119.1 AF012072.2 AK225489.1 AK294883.1 AK302087.1 AK302873.1 AK310195.1 BC030578.1 BC072413.1 BC094683.1 BC136643.1 BC144335.1 BX647897.1 Z34918.1 18 DOTS entries: DT.99973047 DT.446993 DT.100682647 DT.101973463 DT.121449040 DT.75113814 DT.75143879 DT.100660090 DT.95373783 DT.100817621 DT.121448922 DT.95373781 DT.95358735 DT.121448959 DT.86846346 DT.97800634 DT.121448903 DT.92437389 24/268 AceView cDNA sequences (see all 268): AI989287 AA665666 AL044898 BE466545 AA134568 AA678083 N66282 BE670847 BF057034 BU620826 AA903329 AA425125 BP359941 Z34918 BQ721592 BQ425011 BG390109 AI193058 T08424 AI566241 BQ084204 AW263704 CD106562 BM974377
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for EIF4G3 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 25 | ^ | 26 | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30 | ^ | 31 |
|---|
|
| SP1: | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for EIF4G3
|
Expression
for EIF4G3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| EIF4G3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTGTTTTAA
About this image
See EIF4G3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for EIF4G3
SOURCE GeneReport for Unigene cluster: Hs.467084
SABiosciences Custom PCR Arrays for EIF4G3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for EIF4G3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat EIF4G3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat EIF4G3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat EIF4G3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EIF4G3 |
Orthologs
for EIF4G3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for EIF4G3 gene from 8/27 species (see all 27) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
EIF4G31 |
eukaryotic translation initiation factor 4 gamma, 3 |
77.33(n)
79.48(a) |
|
425544 XM_423296.3 XP_423296.3 |
lizard
(Anolis carolinensis) |
Reptilia |
EIF4G36 |
-- |
72(a) |
1 ↔ 1 |
GL343609.1(6852-59904) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.208312 |
Xenopus laevis transcribed sequence with weak similarity more |
84.11(n) |
|
BQ884389.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.204892 |
Transcribed sequence with moderate similarity to protein more |
83.11(n) |
|
AW154022.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG101923 |
translational initiation translation
initiation more |
36(a)
(best of 2) |
|
-- |
worm
(Caenorhabditis elegans) |
Secernentea |
ifg-16 |
Initiation Factor 4G (eIF4G) family member (ifg-1)... |
14(a) |
possible ortholog |
II(8217181-8221459) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
EIF4G1 |
translation initiation factor eIF-4F |
41.18(n)
28.91(a) |
|
825194 NM_001084850.1 NP_001078319.1 |
rice
(Oryza sativa) |
Liliopsida |
Os07g05552001 |
hypothetical protein |
43.61(n)
32.06(a) |
|
4343565 NM_001066493.1 NP_001059958.1 |
ENSEMBL Gene Tree for EIF4G3 (if available)
TreeFam Gene Tree for EIF4G3 (if available) |
Paralogs
for EIF4G3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for EIF4G3 gene
- EIF4G22 EIF4G12
3 SIMAP similar genes for EIF4G3 using alignment to 10 protein entries: IF4G3_HUMAN (see all proteins):EIF4G1 EIF4G1 variant protein EIF4G2
EIF4G3 for paralogs About GeneDecksing
|
Genomic Variants
for EIF4G3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for EIF4G3 (21132972 - 21382972 bp, first 250kb of EIF4G3)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 10 variations for EIF4G3
9 CNVs: 74400 84113 84116 84115 74399 74401 5474 84117 84114
1 Indel: 24058 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing EIF4G3 |
|
Disorders
/ Diseases
for EIF4G3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
EIF4G3 for disorders About GeneDecksing
OMIM gene information: 603929
OMIM disorders: --
3  diseases for EIF4G3: About MalaCardsmouth disease pancreatic cancer pancreatitis
Human Genome Epidemiology (HuGE) Navigator: EIF4G3 (1 document)
Export disorders for EIF4G3 gene to outside databases
|
Publications
for EIF4G3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for EIF4G3 gene, integrated from 9 sources (see all 52):
(articles sorted by number of sources associating them with EIF4G3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel functional human eukaryotic translation initiation factor 4G. (PubMed id 9418880)1, 2, 3, 9 Gradi A....Sonenberg N. (1998)
- Phosphorylation screening identifies translational initiation factor 4GII as an intracellular target of Ca(2+)/calmodulin-dependent protein kinase I. (PubMed id 14507913)1, 2, 9 Qin H.... Edelman A.M. (2003)
- Cleavage of eukaryotic translation initiation factor 4GII within foot-and-mouth disease virus-infected cells: identification of the L- protease cleavage site in vitro. (PubMed id 15016848)1, 2, 9 Gradi A....Belsham G.J. (2004)
- Human rhin4ovirus 2A proteinase cleavage sites in eukaryotic initiation factors (eIF) 4GI and eIF4GII are different. (PubMed id 12663812)1, 2, 9 Gradi A.... Sonenberg N. (2003)
- A newly identified N-terminal amino acid sequence of human eIF4G binds poly(A)-binding protein and functions in poly(A)-dependent translation. (PubMed id 9857202)1, 2, 9 Imataka H.... Sonenberg N. (1998)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Backbone resonance assignment of human eukaryotic translation initiation factor 4E (eIF4E) in complex with 7-methylguanosine diphosphate (m7GDP) and a 17-amino acid peptide derived from human eIF4GII. (PubMed id 12975586)1, 2 Miura T.... Shimma N. (2003)
- A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery. (PubMed id 11172724)1, 2 Marcotrigiano J.... Burley S.K. (2001)
- eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation. (PubMed id 10872469)1, 2 Gingras A.-C.... Sonenberg N. (1999)
|
External Searches for EIF4G3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing EIF4G3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing EIF4G3 gene
(According to HUGE)
About This Section
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Specialized Databases showing EIF4G3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Patent Information for EIF4G3 gene:
Search GeneIP for patents involving EIF4G3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for EIF4G3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for EIF4G3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for EIF4G3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for EIF4G3 | | | OriGene Protein Over-expression Lysate for EIF4G3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for EIF4G3 | | OriGene 3'-UTR Clone for EIF4G3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for EIF4G3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for EIF4G3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for EIF4G3 | | OriGene Custom Protein Services for EIF4G3 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat EIF4G3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing EIF4G3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat EIF4G3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat EIF4G3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat EIF4G3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat EIF4G3 |
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| | | | Search Tocris compounds for EIF4G3 |
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 | | | EIF4G3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EIF4G3 |
|  |  |  | | | | ThermoFisher Antibodies for EIF4G3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat EIF4G3 |
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