Aliases for EIF4E3 Gene
External Ids for EIF4E3 Gene
Previous GeneCards Identifiers for EIF4E3 Gene
EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime cap structure of mRNA and recruit mRNA to the ribosome (Joshi et al., 2004 [PubMed 15153109]).[supplied by OMIM, Mar 2008]
GeneCards Summary for EIF4E3 Gene
EIF4E3 (Eukaryotic Translation Initiation Factor 4E Family Member 3) is a Protein Coding gene. Among its related pathways are Regulation of Glucokinase by Glucokinase Regulatory Protein and Interleukin-3, 5 and GM-CSF signaling. GO annotations related to this gene include RNA binding and translation initiation factor activity. An important paralog of this gene is EIF4E2.
UniProtKB/Swiss-Prot for EIF4E3 Gene
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis. May act as an inhibitor of EIF4E1 activity (By similarity).