Aliases for EIF4E3 Gene
External Ids for EIF4E3 Gene
Previous GeneCards Identifiers for EIF4E3 Gene
EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime cap structure of mRNA and recruit mRNA to the ribosome (Joshi et al., 2004 [PubMed 15153109]).[supplied by OMIM, Mar 2008]
GeneCards Summary for EIF4E3 Gene
EIF4E3 (Eukaryotic Translation Initiation Factor 4E Family Member 3) is a Protein Coding gene. Among its related pathways are Immune System and Interleukin receptor SHC signaling. GO annotations related to this gene include RNA binding and translation initiation factor activity. An important paralog of this gene is EIF4E1B.
UniProtKB/Swiss-Prot for EIF4E3 Gene
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis. May act as an inhibitor of EIF4E1 activity (By similarity).