External Ids for EIF4B Gene
Previous GeneCards Identifiers for EIF4B Gene
GeneCards Summary for EIF4B Gene
EIF4B (Eukaryotic Translation Initiation Factor 4B) is a Protein Coding gene. Diseases associated with EIF4B include Mouth Disease. Among its related pathways are Gene Expression and Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S. GO annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is EIF4H.
UniProtKB/Swiss-Prot for EIF4B Gene
Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.