Aliases for EIF4A2 Gene
External Ids for EIF4A2 Gene
Previous HGNC Symbols for EIF4A2 Gene
Previous GeneCards Identifiers for EIF4A2 Gene
GeneCards Summary for EIF4A2 Gene
EIF4A2 (Eukaryotic Translation Initiation Factor 4A2) is a Protein Coding gene. Among its related pathways are TGF-Beta Pathway and p70S6K Signaling. GO annotations related to this gene include ATP-dependent helicase activity and helicase activity. An important paralog of this gene is EIF4A3.
UniProtKB/Swiss-Prot for EIF4A2 Gene
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon