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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

EIF1 Gene

protein-coding   GIFtS: 55
GCID: GC17P039845

Eukaryotic Translation Initiation Factor 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Eukaryotic Translation Initiation Factor 11 2     EIF1A2
Protein Translation Factor SUI1 Homolog2 3     ISO12
A1212 3     sui1iso12
SUI12 3     Sui1iso13
EIF-12     eIF13

External Ids:    HGNC: 32491   Entrez Gene: 102092   Ensembl: ENSG000001738127   UniProtKB: P415673   

Export aliases for EIF1 gene to outside databases

Previous GC identifers: GC00U990093 GC17P037099 GC17P035607


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for EIF1 Gene: 
EIF1 (eukaryotic translation initiation factor 1) is a protein-coding gene. Diseases associated with EIF1 include vestibular neuronitis, and hepatitis b. GO annotations related to this gene include translation factor activity, nucleic acid binding and translation initiation factor activity. An important paralog of this gene is EIF1B.

UniProtKB/Swiss-Prot: EIF1_HUMAN, P41567
Function: Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal
complexes at the authentic initiation codon of a conventional capped mRNA

Gene Wiki entry for EIF1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.2  NT_010783.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the EIF1 gene promoter:
         C/EBPbeta   C/EBPalpha   AREB6   NF-AT4   NF-AT2   Cart-1   NF-AT3   NF-Y   CBF(2)   NF-AT1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidEIF1 promoter sequence
   Search SABiosciences Chromatin IP Primers for EIF1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat EIF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.2   Ensembl cytogenetic band:  17q21.2   HGNC cytogenetic band: 17q21.2

EIF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
EIF1 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P039845:  view genomic region     (about GC identifiers)

Start:
39,845,127 bp from pter      End:
39,848,920 bp from pter
Size:
3,794 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: EIF1_HUMAN, P41567 (See protein sequence)
Recommended Name: Eukaryotic translation initiation factor 1  
Size: 113 amino acids; 12732 Da
Subunit: Interacts with RENT2
1 PDB 3D structure from and Proteopedia for EIF1:
2IF1 (3D)    
Secondary accessions: Q9UNQ9

Explore the universe of human proteins at neXtProt for EIF1: NX_P41567

Explore proteomics data for EIF1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P41567

  • EIF1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    EIF1 Protein Expression
    REFSEQ proteins: NP_005792.1  
    ENSEMBL proteins: 
     ENSP00000466321   ENSP00000419449   ENSP00000467918  

    Human Recombinant Protein Products for EIF1: 
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    OriGene MassSpec for EIF1 
    OriGene Custom Protein Services for EIF1
    GenScript Custom Purified and Recombinant Proteins Services for EIF1
    Novus Biologicals EIF1 Proteins
    Novus Biologicals EIF1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for EIF1
    Cloud-Clone Corp. Proteins for EIF1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm TAS10347211

    EIF1 for ontologies           About GeneDecksing



    EIF1 Antibody Products: 
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    Assay Products for EIF1: 
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for EIF1 
    Cloud-Clone Corp. CLIAs for EIF1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR001950 TIF_SUI1
     IPR005874 SUI1_euk

    Graphical View of Domain Structure for InterPro Entry P41567

    ProtoNet protein and cluster: P41567

    1 Blocks protein domain: IPB001950 Translation initiation factor SUI1

    UniProtKB/Swiss-Prot: EIF1_HUMAN, P41567
    Similarity: Belongs to the SUI1 family


    EIF1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: EIF1_HUMAN, P41567
    Function: Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal
    complexes at the authentic initiation codon of a conventional capped mRNA

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003743translation initiation factor activity NAS10347211
    GO:0008135translation factor activity, nucleic acid binding TAS10347211
         
    EIF1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for EIF1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for EIF1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for EIF1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for EIF1 

    miRNA
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    8/25 QIAGEN miScript miRNA Assays for microRNAs that regulate EIF1 (see all 25):
    hsa-miR-623 hsa-miR-323-3p hsa-miR-4317 hsa-miR-100* hsa-miR-4328 hsa-miR-300 hsa-miR-522 hsa-miR-570
    SwitchGear 3'UTR luciferase reporter plasmidEIF1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for EIF1
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    Gene Editing
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    Clone
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    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for EIF1
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EIF1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for EIF1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Translation Factors
    Translation Factors
    2RNA transport
    RNA transport
    3Translational Control
    Translational Control

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for EIF1
        Translational Control

    1 BioSystems Pathway for EIF1
        Translation Factors


    1         Kegg Pathway  (Kegg details for EIF1):
        RNA transport


    EIF1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for EIF1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/106 Interacting proteins for EIF1 (P415672, 3 ENSP000004194494) via UniProtKB, MINT, STRING, and/or I2D (see all 106)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    OLFM2O958972, 3MINT-63323 I2D: score=3 
    MAPK6Q166592, 3MINT-8261054 I2D: score=2 
    RASA1P209362, 3, ENSP000002743764MINT-8268207 I2D: score=2 STRING: ENSP00000274376
    EIF3CQ996133, ENSP000003326044I2D: score=8 STRING: ENSP00000332604
    EIF3BP558843, ENSP000003541254I2D: score=7 STRING: ENSP00000354125
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006413translational initiation NAS--
    GO:0006446regulation of translational initiation TAS10347211
    GO:0006950response to stress NAS10347211
    GO:0009048dosage compensation by inactivation of X chromosome IEA--

    EIF1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    EIF1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for EIF1

    2 Novoseek inferred chemical compound relationships for EIF1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    gtp 62.4 17 15601822 (5), 10659855 (1), 16362046 (1), 18593708 (1) (see all 6)
    trna 55.9 5 17956730 (2), 16362046 (1), 17434125 (1)

    Search CenterWatch for drugs/clinical trials and news about EIF1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for EIF1 gene: 
    NM_005801.3  

    Unigene Cluster for EIF1:

    Eukaryotic translation initiation factor 1
    Hs.150580  [show with all ESTs]
    Unigene Representative Sequence: BQ278455
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000462917(uc002hxj.3 uc002hxk.3) ENST00000591776 ENST00000469257
    ENST00000482111 ENST00000310837 ENST00000469308 ENST00000586699
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat EIF1
    8/25 QIAGEN miScript miRNA Assays for microRNAs that regulate EIF1 (see all 25):
    hsa-miR-623 hsa-miR-323-3p hsa-miR-4317 hsa-miR-100* hsa-miR-4328 hsa-miR-300 hsa-miR-522 hsa-miR-570
    SwitchGear 3'UTR luciferase reporter plasmidEIF1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for EIF1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat EIF1
    Clone
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    OriGene clones in human, mouse for EIF1 (see all 7)
    OriGene ORF clones in mouse, rat for EIF1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: EIF1 (NM_001412)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for EIF1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat EIF1
    Sirion Biotech Customized lentivirus for stable overexpression of EIF1 
                         Customized lentivirus expression plasmids for stable overexpression of EIF1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for EIF1
    OriGene qSTAR qPCR primer pairs in human, mouse for EIF1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat EIF1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat EIF1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat EIF1

    Additional mRNA sequence: 

    AF083441.1 AF100737.1 AJ012375.1 AK311209.1 AK311862.1 BC005118.1 BC008710.1 BT006645.1 
    CR457051.1 L26247.1 

    24/54 DOTS entries (see all 54):

    DT.87017930  DT.97857707  DT.87000962  DT.100060625  DT.100688807  DT.91769712  DT.100688802  DT.95170862 
    DT.91932427  DT.40124100  DT.95170828  DT.100688801  DT.95170729  DT.121022158  DT.92379834  DT.120959094 
    DT.120959090  DT.120959114  DT.100688811  DT.100866432  DT.120959199  DT.97852514  DT.97852539  DT.100688792 

    24/2215 AceView cDNA sequences (see all 2215):

    T70048 BU732309 BM661902 AA632428 F03160 AW515106 CR592450 AA576224 
    AA010890 W56503 AA009621 BI260437 BQ679393 BI833162 Z28719 F03369 
    CD251521 W94260 AV650601 CB160905 BQ684557 AV660497 BU579641 AW073398 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for EIF1 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b · 4c · 4d · 4e
    SP1:                          -     -                                                   
    SP2:                          -     -                                                   
    SP3:                          -     -     -                                             
    SP4:                          -     -                                                   
    SP5:                                -                                                   


    ECgene alternative splicing isoforms for EIF1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    EIF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAATAAACTG
    EIF1 Expression
    About this image


    See EIF1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for EIF1

    SOURCE GeneReport for Unigene cluster: Hs.150580
        SABiosciences Custom PCR Arrays for EIF1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EIF1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for EIF1 gene from 9/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Eif15
    Gm54711
    eukaryotic translation initiation factor 15
    predicted pseudogene 54711
    94.1(n)1
    91.15(a)1
      11 (63.46 cM)5
    4329501  XM_001473255.21  XP_001473305.11 
     1003198855 
    chicken
    (Gallus gallus)
    Aves EIF16
    Eukaryotic translation initiation factor 1
    83(a)
    1 ↔ 1
    27(4505836-4644100)
    lizard
    (Anolis carolinensis)
    Reptilia EIF16
    eukaryotic translation initiation factor 1
    99(a)
    1 ↔ 1
    6(70956314-70962904)
    zebrafish
    (Danio rerio)
    Actinopterygii wufb54a122 wufb54a12 82.2(n)   322237  AY398352.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG177376
    --
    70(a)
    1 → many
    3L(3223341-3224650)
    worm
    (Caenorhabditis elegans)
    Secernentea eif-16
    Protein EIF-1
    51(a)
    1 → many
    II(4990831-4993582)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SUI16
    Translation initiation factor eIF1; component of a...
    56(a)
    1 → many
    XIV(187170-187496)
    soybean
    (Glycine max)
    eudicotyledons 445176982   -- 73.36(n)  
    barley
    (Hordeum vulgare)
    Liliopsida AJ476519.12   -- 72.3(n)    AJ476519.1 


    ENSEMBL Gene Tree for EIF1 (if available)
    TreeFam Gene Tree for EIF1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for EIF1 gene
    EIF1B2  
    3 SIMAP similar genes for EIF1 using alignment to 3 protein entries:     EIF1_HUMAN (see all proteins):
    SUI1    EIF1B    GC20

    EIF1 for paralogs           About GeneDecksing


    5/7 Pseudogenes.org Pseudogenes for EIF1 (see all 7)
    PGOHUM00000248699 PGOHUM00000236978 PGOHUM00000234120 PGOHUM00000243973 PGOHUM00000245114


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/152 SNPs in EIF1 are shown (see all 152)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs571537921,2
    C,F--39843198(+) CAGCCA/GGAATG 1 -- us2k13Minor allele frequency- G:0.21WA CSA 122
    rs1857116441,2
    --39843287(+) TTGGCA/GCCTCT 1 -- us2k10--------
    rs596414681,2
    --39843370(+) ATGGCA/GCCATC 1 -- us2k10--------
    rs1893146831,2
    --39843401(+) CTTCCC/TGGGTT 1 -- us2k10--------
    rs556675601,2
    C,F--39843411(+) TCAAAT/CAATTA 1 -- us2k13Minor allele frequency- C:0.21WA CSA 122
    rs1389291681,2
    --39843434(+) CTCCCA/GAGTAG 1 -- us2k10--------
    rs1819057011,2
    C--39843457(+) GCACAC/TGCCAC 1 -- us2k10--------
    rs1159279111,2
    C,F--39843601(+) ACAGCG/ACCCAG 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1854897971,2
    --39843633(+) TTAGTC/GGCTCT 1 -- us2k10--------
    rs1172945551,2
    C,F--39843645(+) TCTCCC/TGCTGG 1 -- us2k11Minor allele frequency- T:0.01NA 120

    HapMap Linkage Disequilibrium report for EIF1 (39845127 - 39848920 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for EIF1:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv962e1CNV Complex17122850
    dgv961e1CNV Complex17122850

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    4 diseases for EIF1:    About MalaCards
    vestibular neuronitis    hepatitis b    neuronitis    hepatitis


    EIF1 for disorders           About GeneDecksing


    Export disorders for EIF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for EIF1 gene, integrated from 9 sources (see all 47):
    (articles sorted by number of sources associating them with EIF1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of a human genotoxic and endoplasmic reticulum stress-inducible cDNA that encodes translation initiation factor 1 (eIF1(A121/SUI1)). (PubMed id 10347211)1, 2, 3 Sheikh M.S.... Fornace A.J. Jr. (1999)
    2. Expressed sequence tags identify a human isolog of the suil translation initiation factor. (PubMed id 7904817)1, 2, 3 Fields C.A. and Adams M.D. (1994)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexes. (PubMed id 11073994)1, 2 Mendell J.T.... Dietz H.C. (2000)
    5. Structure and interactions of the translation initiation factor eIF1. (PubMed id 10228174)1, 2 Fletcher C.M.... Wagner G. (1999)
    6. Coordinated movements of eukaryotic translation initia tion factors eIF1, eIF1A, and eIF5 trigger phosphate release from eIF2 in respon se to start codon recognition by the ribosomal preinitiation complex. (PubMed id 23293029)1 Nanda J.S....Lorsch J.R. (2013)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    9. Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
    10. The C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2b. (PubMed id 22813744)1 Luna R.E....Wagner G. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10209 HGNC: 3249 AceView: SUI1 Ensembl:ENSG00000173812 euGenes: HUgn10209
    ECgene: EIF1 Kegg: 10209 H-InvDB: EIF1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for EIF1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for EIF1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for EIF1 gene:
    Search GeneIP for patents involving EIF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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