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EGR1 Gene

protein-coding GIFtS: 71

GC05P137829

early growth response 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
AT225 ^¹, ², ³
EGR-1 ^³
G0S30 ^¹, ²
KROX-24 ^¹, ²
NGFI-A ^¹, ², ³
TIS8 ^¹, ²
ZIF-268 ^¹, ²
ZNF225 ^¹, ², ³

Descriptions
Nerve growth factor-induced protein A ^², ³
Protein Krox-24 ^³
Transcription factor ETR103 ^², ³
Transcription factor Zif268 ^³
Zinc finger protein 225 ^², ³
early growth response 1 ^²
early growth response protein 1 ^²

External Ids
HGNC: 3238¹
Entrez Gene: 1958²
UniProtKB: P18146³
Ensembl: ENSG00000120738⁷

Search outside databases for aliases for EGR1 gene

Previous GC identifers: GC05P137675 GC05P138476 GC05P137832 GC05P137877

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for EGR1:

The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is

a nuclear protein and functions as a transcriptional regulator. The products of target genes it

activates are required for differentitation and mitogenesis. Studies suggest this is a cancer

suppresor gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: EGR1_HUMAN, P18146

Function: Transcriptional regulator. Recognizes and binds to the DNA sequence

5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required

for mitogenesis and differentiation

Gene Wiki entry for EGR1 (Zif268)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the EGR1 gene

Entrez Gene cytogenetic band: 5q31.1 Ensembl cytogenetic band: 5q31.2 HGNC cytogenetic band: 5q23-q31

EGR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 5 GeneLoc Exon Structure

GeneLoc location for GC05P137829: (about GC identifiers)

Start:	137,829,080 bp from pter
End:	137,832,903 bp from pter
Size:	3,824 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000005.8 NT_034772.5

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: EGR1_HUMAN, P18146 (See protein sequence)

Recommended Name: Early growth response protein 1

Size: 543 amino acids; 57507 Da

Subcellular location: Nucleus

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_001955.1

ENSEMBL proteins:

ENSP00000239938

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Sigma-Aldrich Proteins for EGR1
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Egr1 + Egr2, Egr1)
	Human Recombinant Proteins from Abnova (EGR1)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	IEA	--
GO:0005634	nucleus	IDA	14744935

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Antibodies for EGR1:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of EGR1
	Sigma-Aldrich Antibodies for EGR1
	R&D Systems Antibodies for EGR1
	Cell Signaling Technology (CST) Antibodies for EGR1 (Egr-1)
	Antibodies from Abcam (Egr1 + Egr2, Egr1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (EGR1)
	Novus Biologicals Antibodies for EGR1

Assays for EGR1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry P18146

ProtoNet protein and cluster: P18146

1 Blocks protein family: IPB007086 C2H2-type zinc finger signature

UniProtKB/Swiss-Prot: EGR1_HUMAN, P18146

Similarity: Belongs to the EGR C2H2-type zinc-finger protein family

Similarity: Contains 3 C2H2-type zinc fingers

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (EGR1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (EGR1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001964

Applied Biosystems Silencer® siRNAs for EGR1

Sigma-Aldrich siRNA for EGR1

Sigma-Aldrich shRNA Panels and shRNA for EGR1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_001964
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001964
untagged cDNA clone in CMV expression vector: NM_001964

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001964

UniProtKB/Swiss-Prot: EGR1_HUMAN, P18146

Function: Transcriptional regulator. Recognizes and binds to the DNA sequence

5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required

for mitogenesis and differentiation

Induction: By growth factors

Genatlas biochemistry entry for EGR1:

immediate early growth response,gene 1 (pAT225),nerve growth factor induced clone A,specifically

expressed in Schwann cells,induced by a wide variety of extracellular stimuli,involved in cell

proliferation,macrophage differentiation,synaptic activation and long term

potentiation,coactivated by CREBBP

6 MGI mutant phenotypes (inferred from 4 alleles) (MGI details for Egr1):

behavior/neurological	endocrine/exocrine gland	growth/size	homeostasis/metabolism	nervous system
reproductive system

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	transcription factor activity	IDA	12560508
GO:0008270	zinc ion binding	IEA	--
GO:0016563	transcription activator activity	IEA	--
GO:0046872	metal ion binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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4 Sigma-Aldrich "Your Favorite Gene" Pathways for EGR1 (Your Favorite Gene powered by Ingenuity)

CXCR4 Signaling
CDK5 Signaling
B Cell Receptor Signaling
GNRH Signaling

GeneDecks EGR1 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for EGR1

5/171 Interacting proteins for EGR1 (ENSP00000239938³ P18146²) via UniProtKB, MINT, and/or STRING (see all 171 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TP53	P04637²	STRING (score=.974) MINT-4793180
CDKN2A	Q8N726²	MINT-7011792 MINT-7011820 MINT-7011781 MINT-7011806
SUMO1	P63165²	MINT-7011835
SUMO1P3	P63165²	MINT-7011835
NAB1	ENSP00000336894³	STRING (score=.99)

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5/6 Gene Ontology (GO) biological process terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	IEA	--
GO:0007611	learning or memory	IEA	--
GO:0030217	T cell differentiation	IEA	--
GO:0045941	positive regulation of transcription	IDA	12560508

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for EGR1
10/47 Novoseek chemical compound relationships for EGR1 gene (see all 47 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
zinc	67.15	117	8132543 (4), 9485332 (3), 8336701 (2), 10671503 (2) (see all 69)
pd 98,059	63.57	21	17230532 (2), 11121417 (2), 12483323 (1), 12457461 (1) (see all 19)
ptx1	57.36	4	10859489 (2), 10082522 (1), 15469090 (1)
12-o-tetradecanoylphorbol 13-acetate	54.98	37	15910736 (4), 8018558 (2), 1417981 (2), 11751871 (1) (see all 16)
phorbol-12-myristate	49.35	4	7519845 (1), 11007455 (1), 15231681 (1), 10674404 (1)
phosphatidylinositol	42.39	27	10050043 (4), 8302296 (2), 16424010 (2), 11403719 (2) (see all 17)
okadaic acid	40.64	34	8174132 (9), 12570057 (6), 8381016 (6), 1320009 (3) (see all 8)
thymidine	37.56	12	19062733 (1), 16806337 (1), 8366092 (1), 8664375 (1) (see all 8)
oligonucleotide	36.75	19	11830539 (2), 12570057 (1), 16995904 (1), 7673192 (1) (see all 9)
tyrosine	34.84	38	16515541 (3), 11053775 (3), 8398902 (2), 9012782 (2) (see all 21)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (EGR1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (EGR1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001964

Sigma-Aldrich siRNA for EGR1

Sigma-Aldrich shRNA Panels and shRNA for EGR1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001964

REFSEQ mRNAs for EGR1 gene:

NM_001964.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001964

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001964
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001964
                                 untagged cDNA clone in CMV expression vector: NM_001964

Additional cDNA sequence: M24019.1

16 DOTS entries:

DT.451515 DT.92410441 DT.92444091 DT.100815176 DT.92444078 DT.100652567 DT.100815174 DT.100838251

DT.100815170 DT.120828084 DT.75188226 DT.92444088 DT.95168866 DT.95288077 DT.91927235 DT.95243780

24/292 AceView cDNA sequences (see all 292 ):

AI937024 AL602754 BQ447364 AI480152 BM310258 AI479169 NM_001964 BU952514

AA327331 BG059835 AI625815 D57841 AA679209 AI582664 M80583 AI701078

BX425480 AA366121 CK905254 AA300268 BQ723542 CA435715 CD238597 BX645009

highest scoring ESTs for EGR1:

X52541 AA158960 AA158961 AA298861 AA300267 AA318923 AA327331 AA327475 AA356929 AA366121

Unigene Clusters for EGR1:

Early growth response 1

Hs.326035 [show with all ESTs], Hs.708393 [show with all ESTs]

Unigene Representative Sequences: NM_001964, CD522629

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000239938

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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EGR1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for EGR1

¹ / ² / ³

5 probe-sets matching EGR1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
789_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	X52541	1.00	1.00	1.00	1
201694_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_001964	0.60	1.00	0.82	1
201693_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AV733950	0.60	1.00	0.82	1
201694_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
201693_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GGATATGTGG

SOURCE GeneReport for Unigene clusters: Hs.326035 Hs.708393
Expression variation in blood from EXPOLDB for EGR1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for EGR1 gene from 5/12 species (see all 12 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	EGR1¹	--	early growth response 1	91(n) 94.64(a)	481528 XM_846145.1 XP_851238.1
chimpanzee (Pan troglodytes)	EGR1¹	--	early growth response 1	98.69(n) 98.43(a)	462097 XM_517958.2 XP_517958.2
cow (Bos taurus)	EGR1¹	--	early growth response 1	91.16(n) 94.43(a)	407125 NM_001045875.1 NP_001039340.1
rat (Rattus norvegicus)	Egr1¹	--	early growth response 1	87.25(n) 92.5(a)	24330 NM_012551.1 NP_036683.1
mouse (Mus musculus)	Egr1^{1, 5}	18 (16.00 cM)⁵	early growth response 1^{1, 5}	87.59(n)¹ 93.42(a)¹	13653¹ NM_007913.5¹ NP_031939.1¹ AK037837⁵ AK040925⁵ (see all 19)

About this table Species with no ortholog for EGR1

ENSEMBL Gene Tree for EGR1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for EGR1 gene

EGR3² EGR2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/32 NCBI SNPs in EGR1 are shown (see all 32 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 33)

AB	SNP ID	Valid	Chr 5 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs3813321^1,2	A,C,F	137827923(+)	`CCAGAC/TAGCCC`	1	--	ng5¹		1	EA	1096
--	rs13181973^1,2	C,H	137829432(+)	`GCCCAC/TCATGG`	1	T/I	mis¹ ese³		4	EU EA WA	406
	rs6914^1,2	C,F	137832534(+)	`ATGATT/CTGGGG`	1	--	ut3¹		7	MN CSAM EA	776
	rs2294175^1,2	C,H	137831892(+)	`TGCCTG/CAAACA`	1	--	ut3¹		9	MN CSAM EA EU WA	826
	rs1800778^1,2	C,F	137828912(+)	`GGGCGC/TTGTCG`	1	--	ng5¹		2	MN	1088
--	rs35657506^1,2	F	137832409(+)	`TTCGTC/TCTTTT`	1	--	ut3¹		5	MN CSAM EA	400
	rs34944417^1,2	F	137832995(+)	`TCCTCC/TAGCCA`	1	--	ng3¹		5	MN CSAM EA	396
	rs1803556^1,2	C	137832140(+)	`TTCTAT/GTGTAT`	1	--	ut3¹		5	MN CSAM EA	408
--	rs34838824^1,2	F	137828153(+)	`ACAGGG/AGACCC`	1	--	ng5¹		5	MN CSAM EA	408
--	rs6865407^1,2	C	137832965(+)	`CTGAAG/AACTTG`	1	--	ng3¹		5	MN CSAM EA	404

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HapMap Linkage Disequilibrium images for EGR1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 128990

10/77 Novoseek disease relationships for EGR1 gene (see all 77 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
wilms tumor	51.60	17	11106242 (5), 7823937 (1), 11734301 (1), 1367123 (1) (see all 11)
tumors	45.06	164	9212230 (6), 15774784 (6), 16093249 (5), 11135623 (4) (see all 89)
myeloid leukemia	39.02	5	1864967 (1), 8381016 (1), 7690249 (1), 7706752 (1) (see all 5)
necrosis	36.73	29	11586099 (1), 14726502 (1), 18814180 (1), 1730654 (1) (see all 26)
monocytic leukemia	34.89	3	11734301 (2), 2064996 (1)
leukemia t-cell	32.93	1	1359492 (1)
fibrosarcoma	32.89	15	8876223 (2), 9714058 (2), 11121417 (2), 7585551 (1) (see all 9)
carcinoma embryonal	31.12	6	1909429 (1), 8180132 (1), 8176254 (1), 9824160 (1) (see all 5)
pheochromocytoma	29.26	2	10604389 (1), 17102092 (1)
glioblastoma	28.42	10	10783396 (4), 11555594 (1), 18316600 (1), 12890669 (1) (see all 6)

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1 PharmGKB disease relationship for EGR1 gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Asthma	FA	15003938

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Genetic Association Database: EGR1
Human Genome Epidemiology Navigator: EGR1 (4 documents)
Tumor Gene Database: EGR1

(Possibly Related Articles in Doctor's Guide)
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Scientists Discover New Approaches to Manipulating AIDS Virus

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/811 PubMed articles for EGR1 gene (see all 811 ):

Induction of early growth-response factor 1 by platelet-derived growth factor in human airway smooth muscle. (PubMed id 15003938)^{1, 3, 7} Hjoberg J....Silverman E.S. (2004)
A gene coding for a zinc finger protein is induced during 12-O- tetradecanoylphorbol-13-acetate-stimulated HL-60 cell differentiation. (PubMed id 1569051)^{1, 3, 4} Shimizu N....Utiyama H. (1992)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Expression of a zinc finger gene in HTLV-I- and HTLV-II-transformed cells. (PubMed id 2110381)^{3, 4} Wright J.J....Siebenlist U. (1990)
cDNA sequence of the human cellular early growth response gene Egr- 1. (PubMed id 2377485)^{3, 4} Suggs S.V.... Sukhatme V.P. (1990)
A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization. (PubMed id 3127059)^{2, 3} Sukhatme V.P....Curran T. (1988)
Basal EGR-1 (zif268, NGFI-A, Krox-24) expression in developing striatal patches: role of dopamine and glutamate. (PubMed id 12470865)^{1, 3} Snyder-Keller A....Mitchell E.S. (2002)
Concurrent down-regulation of Egr-1 and gelsolin in the majority of human breast cancer cells. (PubMed id 18204200)^{1, 3} Liu J....Huang R.P. (2007)
Regulation of expression of the early growth response gene-1 (EGR-1) in malignant and benign cells of the prostate. (PubMed id 15486985)^{1, 3} Mora G.R....Tindall D.J. (2005)
The egr-1 gene is induced by DNA-damaging agents and non-genotoxic drugs in both normal and neoplastic human cells. (PubMed id 12706485)^{1, 3} Quinones A....Rainov N.G. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 1958	HGNC: 3238	AceView: EGR1	Ensembl:ENSG00000120738	euGenes: HUgn1958
ECgene: EGR1	H-InvDB: EGR1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for EGR1	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for EGR1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for EGR1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for EGR1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for EGR1		Antibodies for EGR1
	Explore super-pooled esiRNAs		Proteins for EGR1
	Lentivirus-delivered shRNAs for EGR1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (EGR1)
	Antibodies (EGR1)
	Chimera RNAi (EGR1)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Antibodies & Assays for EGR1 (Egr-1)

	Recombinant Proteins (Egr1 + Egr2, Egr1)
	Antibodies (Egr1 + Egr2, Egr1)

Search OriGene for EGR1

Search Tocris compounds for EGR1

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Antibodies for EGR1

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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EGR1 Gene at Home site.
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EGR1 Gene

protein-coding GIFtS: 71

Aliases &
Descriptions
for EGR1

Summaries
for EGR1

Genomic Location
for EGR1

Proteins
for EGR1

Protein Domains/
Families
for EGR1

Gene Function
for EGR1

Pathways & Interactions
for EGR1

Drugs & Compounds
for EGR1

Transcripts
for EGR1

Expression
for EGR1

Orthologs
for EGR1

Paralogs
for EGR1

SNPs/Variants
for EGR1

Disorders & Mutations
for EGR1

Medical News
for EGR1

Publications
for EGR1

Search for EGR1

Genome Databases showing EGR1

Other Databases showing EGR1

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Licensable Technologies
for EGR1

Services
for EGR1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

EGR1 Gene

protein-coding GIFtS: 71

Aliases & Descriptionsfor EGR1

Summariesfor EGR1

Genomic Locationfor EGR1

Proteinsfor EGR1

Protein Domains/Familiesfor EGR1

Gene Functionfor EGR1

Pathways & Interactionsfor EGR1

Drugs & Compoundsfor EGR1

Transcriptsfor EGR1

Expression for EGR1

Orthologsfor EGR1

Paralogsfor EGR1

SNPs/Variantsfor EGR1

Disorders & Mutationsfor EGR1

Medical Newsfor EGR1

Publicationsfor EGR1

Search for EGR1

Genome Databases showing EGR1

Other Databases showing EGR1

Specialized Databases showing EGR1

Licensable Technologiesfor EGR1

Servicesfor EGR1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for EGR1

Summaries
for EGR1

Genomic Location
for EGR1

Proteins
for EGR1

Protein Domains/
Families
for EGR1

Gene Function
for EGR1

Pathways & Interactions
for EGR1

Drugs & Compounds
for EGR1

Transcripts
for EGR1

Expression
for EGR1

Orthologs
for EGR1

Paralogs
for EGR1

SNPs/Variants
for EGR1

Disorders & Mutations
for EGR1

Medical News
for EGR1

Publications
for EGR1

Licensable Technologies
for EGR1

Services
for EGR1