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Aliases for EGOT Gene

Subcategory (RNA class) for EGOT Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for EGOT Gene

  • Eosinophil Granule Ontogeny Transcript (Non-Protein Coding) 2 3 5
  • Eosinophil Granule Ontogeny 2
  • Non-Protein Coding RNA 190 2
  • NCRNA00190 3
  • EGO 3

External Ids for EGOT Gene

Summaries for EGOT Gene

GeneCards Summary for EGOT Gene

EGOT (Eosinophil Granule Ontogeny Transcript (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with EGOT include Carpal Tunnel Syndrome, Familial and Nerve Compression Syndrome.

Gene Wiki entry for EGOT Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for EGOT Gene

Genomics for EGOT Gene

Regulatory Elements for EGOT Gene

Enhancers for EGOT Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03F004717 1.7 FANTOM5 Ensembl ENCODE 12.7 +30.2 30234 6.9 HDGF PKNOX1 ATF1 ARNT MLX ARID4B SIN3A ZNF48 YY1 ZNF766 ARL8B BHLHE40 EGOT BHLHE40-AS1 ENSG00000235978 EDEM1 ENSG00000275981 LOC105376933
GH03F004866 1.8 FANTOM5 Ensembl ENCODE 10.8 -116.6 -116560 4.0 HDGF PKNOX1 CREB3L1 SIN3A FEZF1 YY1 CBX5 ZNF143 FOS KLF13 ARL8B EGOT BHLHE40 EDEM1 ITPR1 ENSG00000235978
GH03F004975 1.7 FANTOM5 ENCODE 11.3 -231.2 -231171 14.4 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 BHLHE40 ARL8B ENSG00000235978 EGOT EDEM1 ITPR1 BHLHE40-AS1 LOC105376934
GH03F004770 1.3 Ensembl ENCODE 13.3 -20.8 -20799 2.8 HDGF ATF1 PKNOX1 ARNT CREB3L1 CBX5 KLF13 JUNB NCOA1 REST EGOT ENSG00000235978
GH03F004847 1.5 FANTOM5 Ensembl ENCODE 11 -98.3 -98313 4.0 HDGF HDAC1 PKNOX1 TBL1XR1 BMI1 ZBTB40 CHAMP1 GATA2 CBX5 ETV6 ENSG00000235978 EGOT BHLHE40
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around EGOT on UCSC Golden Path with GeneCards custom track

Genomic Location for EGOT Gene

Chromosome:
3
Start:
4,749,192 bp from pter
End:
4,751,590 bp from pter
Size:
2,399 bases
Orientation:
Minus strand

Genomic View for EGOT Gene

Genes around EGOT on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
EGOT Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for EGOT Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for EGOT Gene

Proteins for EGOT Gene

Post-translational modifications for EGOT Gene

No Post-translational modifications

No data available for DME Specific Peptides for EGOT Gene

Domains & Families for EGOT Gene

Gene Families for EGOT Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with EGOT: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for EGOT Gene

Function for EGOT Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for EGOT Gene

Localization for EGOT Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for EGOT Gene

Pathways & Interactions for EGOT Gene

No Data Available

Interacting Proteins for EGOT Gene

Gene Ontology (GO) - Biological Process for EGOT Gene

None

No data available for Pathways by source and SIGNOR curated interactions for EGOT Gene

Transcripts for EGOT Gene

mRNA/cDNA for EGOT Gene

(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for EGOT Gene

Eosinophil granule ontogeny transcript (non-protein coding):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for EGOT Gene

No ASD Table

Relevant External Links for EGOT Gene

GeneLoc Exon Structure for
EGOT
ECgene alternative splicing isoforms for
EGOT

Expression for EGOT Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for EGOT Gene

mRNA differential expression in normal tissues according to GTEx for EGOT Gene

This gene is overexpressed in Kidney - Cortex (x14.3), Pancreas (x4.6), and Breast - Mammary Tissue (x4.2).

NURSA nuclear receptor signaling pathways regulating expression of EGOT Gene:

EGOT

SOURCE GeneReport for Unigene cluster for EGOT Gene:

Hs.663059
genes like me logo Genes that share expression patterns with EGOT: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for EGOT Gene

Orthologs for EGOT Gene

Evolution for EGOT Gene

ENSEMBL:
Gene Tree for EGOT (if available)
TreeFam:
Gene Tree for EGOT (if available)

No data available for Orthologs for EGOT Gene

Paralogs for EGOT Gene

No data available for Paralogs for EGOT Gene

Variants for EGOT Gene

Sequence variations from dbSNP and Humsavar for EGOT Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1061774 -- 4,750,810(-) TTTCC(A/G)GAGAC intron-variant
rs112264323 -- 4,752,492(+) CAGCT(G/T)CCTTT intron-variant, upstream-variant-2KB
rs113319659 -- 4,749,363(+) ATCCC(A/G)TAGTA intron-variant, nc-transcript-variant
rs114292907 -- 4,748,888(+) GACGC(A/G)AAGTT intron-variant
rs114713260 -- 4,753,038(+) GAGAT(A/G)CCGTT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for EGOT Gene

Variant ID Type Subtype PubMed ID
esv3893643 CNV loss 25118596
nsv1005718 CNV gain 25217958
nsv460357 CNV loss 19166990
nsv589454 CNV loss 21841781

Relevant External Links for EGOT Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
EGOT

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for EGOT Gene

Disorders for EGOT Gene

MalaCards: The human disease database

(2) MalaCards diseases for EGOT Gene - From: DISEASES

Disorder Aliases PubMed IDs
carpal tunnel syndrome, familial
  • carpal tunnel syndrome
nerve compression syndrome
  • compression neuropathy
- elite association - COSMIC cancer census association via MalaCards
Search EGOT in MalaCards View complete list of genes associated with diseases

Relevant External Links for EGOT

Genetic Association Database (GAD)
EGOT
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
EGOT
genes like me logo Genes that share disorders with EGOT: view

No data available for UniProtKB/Swiss-Prot and Genatlas for EGOT Gene

Publications for EGOT Gene

  1. Molecular evolution of the non-coding eosinophil granule ontogeny transcript. (PMID: 22303364) Rose D. … Stadler P.F. (Front Genet 2011) 2 3 64
  2. EGO, a novel, noncoding RNA gene, regulates eosinophil granule protein transcript expression. (PMID: 17351112) Wagner L.A. … Gleich G.J. (Blood 2007) 2 3 64
  3. Downregulation of the long noncoding RNA EGOT correlates with malignant status and poor prognosis in breast cancer. (PMID: 26159853) Xu S.P. … Pang D. (Tumour Biol. 2015) 3 64
  4. Large-scale genotyping identifies 41 new loci associated with breast cancer risk. (PMID: 23535729) Michailidou K. … Easton D.F. (Nat. Genet. 2013) 3 64
  5. A genome-wide association study identifies a potential novel gene locus for keratoconus, one of the commonest causes for corneal transplantation in developed countries. (PMID: 21979947) Li X. … Rabinowitz Y.S. (Hum. Mol. Genet. 2012) 46 64

Products for EGOT Gene

Sources for EGOT Gene

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