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Aliases for EGOT Gene

Subcategory (RNA class) for EGOT Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for EGOT Gene

  • Eosinophil Granule Ontogeny Transcript (Non-Protein Coding) 2 3 5
  • Eosinophil Granule Ontogeny 2
  • Non-Protein Coding RNA 190 2
  • NCRNA00190 3
  • EGO 3

External Ids for EGOT Gene

Summaries for EGOT Gene

GeneCards Summary for EGOT Gene

EGOT (Eosinophil Granule Ontogeny Transcript (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with EGOT include Carpal Tunnel Syndrome, Familial and Nerve Compression Syndrome.

Gene Wiki entry for EGOT Gene

Additional gene information for EGOT Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for EGOT Gene

Genomics for EGOT Gene

Regulatory Elements for EGOT Gene

Enhancers for EGOT Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03H004717 1.9 FANTOM5 Ensembl ENCODE dbSUPER 12.8 +30.8 30834 5 FOXA2 ATF1 MLX ARNT ARID4B YBX1 YY1 GATA2 ZNF143 FOS ARL8B BHLHE40 EGOT BHLHE40-AS1 ENSG00000235978 EDEM1 ENSG00000275981 LOC105376933
GH03H004866 2 FANTOM5 Ensembl ENCODE dbSUPER 10.8 -116.6 -116560 3 HDGF FOXA2 PKNOX1 ARNT SIN3A FEZF1 YY1 ZNF766 CBX5 ZNF143 ARL8B EGOT BHLHE40 EDEM1 ITPR1 ENSG00000235978
GH03H004975 1.9 FANTOM5 ENCODE dbSUPER 11.3 -231.2 -231171 14 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 ZC3H11A MEF2D BHLHE40 ARL8B ENSG00000235978 EGOT SETMAR EDEM1 ITPR1 BHLHE40-AS1 LOC105376934
GH03H005051 1.7 FANTOM5 Ensembl ENCODE dbSUPER 11 -302.4 -302396 5 HDGF PKNOX1 RB1 ARNT NFXL1 YBX1 BATF GATA2 ZNF207 ATF7 BHLHE40 BHLHE40-AS1 ENSG00000235978 EGOT ARL8B EDEM1 GC03M005068 LOC105376934
GH03H004776 1.4 Ensembl ENCODE dbSUPER 13.2 -26.0 -26021 2 HDGF PKNOX1 BMI1 YBX1 BATF ZNF207 FOS ATF7 ETV6 RUNX3 EGOT ENSG00000235978
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around EGOT on UCSC Golden Path with GeneCards custom track

Genomic Location for EGOT Gene

Chromosome:
3
Start:
4,749,192 bp from pter
End:
4,751,590 bp from pter
Size:
2,399 bases
Orientation:
Minus strand

Genomic View for EGOT Gene

Genes around EGOT on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
EGOT Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for EGOT Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for EGOT Gene

Proteins for EGOT Gene

Post-translational modifications for EGOT Gene

No Post-translational modifications

No data available for DME Specific Peptides for EGOT Gene

Domains & Families for EGOT Gene

Gene Families for EGOT Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with EGOT: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for EGOT Gene

Function for EGOT Gene

Phenotypes From GWAS Catalog for EGOT Gene

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for EGOT
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for EGOT Gene

Localization for EGOT Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for EGOT Gene

Pathways & Interactions for EGOT Gene

No Data Available

Interacting Proteins for EGOT Gene

Gene Ontology (GO) - Biological Process for EGOT Gene

None

No data available for Pathways by source and SIGNOR curated interactions for EGOT Gene

Drugs & Compounds for EGOT Gene

No Compound Related Data Available

Transcripts for EGOT Gene

mRNA/cDNA for EGOT Gene

(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for EGOT Gene

Eosinophil granule ontogeny transcript (non-protein coding):
Representative Sequences:

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for EGOT
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for EGOT Gene

No ASD Table

Relevant External Links for EGOT Gene

GeneLoc Exon Structure for
EGOT
ECgene alternative splicing isoforms for
EGOT

Expression for EGOT Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for EGOT Gene

mRNA differential expression in normal tissues according to GTEx for EGOT Gene

This gene is overexpressed in Kidney - Cortex (x14.3), Pancreas (x4.6), and Breast - Mammary Tissue (x4.2).

NURSA nuclear receptor signaling pathways regulating expression of EGOT Gene:

EGOT

SOURCE GeneReport for Unigene cluster for EGOT Gene:

Hs.663059
genes like me logo Genes that share expression patterns with EGOT: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for EGOT Gene

Orthologs for EGOT Gene

Evolution for EGOT Gene

ENSEMBL:
Gene Tree for EGOT (if available)
TreeFam:
Gene Tree for EGOT (if available)

No data available for Orthologs for EGOT Gene

Paralogs for EGOT Gene

No data available for Paralogs for EGOT Gene

Variants for EGOT Gene

Sequence variations from dbSNP and Humsavar for EGOT Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1000015475 -- 4,748,962(+) GGGGA(C/T)TTAGA intron-variant
rs1000053562 -- 4,749,942(+) CTGTG(C/T)AGTGC intron-variant, nc-transcript-variant
rs1000109577 -- 4,752,318(+) GGTGC(A/G)CAAAT intron-variant, upstream-variant-2KB
rs1000151195 -- 4,749,187(+) AAGAA(C/T)AAACT intron-variant
rs1000652768 -- 4,748,793(+) TCGGT(A/T)ATCAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for EGOT Gene

Variant ID Type Subtype PubMed ID
esv3893643 CNV loss 25118596
nsv1005718 CNV gain 25217958
nsv460357 CNV loss 19166990
nsv589454 CNV loss 21841781

Relevant External Links for EGOT Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
EGOT

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for EGOT Gene

Disorders for EGOT Gene

MalaCards: The human disease database

(2) MalaCards diseases for EGOT Gene - From: DISEASES

Disorder Aliases PubMed IDs
carpal tunnel syndrome, familial
  • carpal tunnel syndrome
nerve compression syndrome
  • compression neuropathy
- elite association - COSMIC cancer census association via MalaCards
Search EGOT in MalaCards View complete list of genes associated with diseases

Relevant External Links for EGOT

Genetic Association Database (GAD)
EGOT
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
EGOT
genes like me logo Genes that share disorders with EGOT: view

No data available for UniProtKB/Swiss-Prot and Genatlas for EGOT Gene

Publications for EGOT Gene

  1. Molecular evolution of the non-coding eosinophil granule ontogeny transcript. (PMID: 22303364) Rose D … Stadler PF (Frontiers in genetics 2011) 2 3 60
  2. EGO, a novel, noncoding RNA gene, regulates eosinophil granule protein transcript expression. (PMID: 17351112) Wagner LA … Gleich GJ (Blood 2007) 2 3 60
  3. Long noncoding RNA EGOT negatively affects the antiviral response and favors HCV replication. (PMID: 27283940) Carnero E … Fortes P (EMBO reports 2016) 3 60
  4. Downregulation of the long noncoding RNA EGOT correlates with malignant status and poor prognosis in breast cancer. (PMID: 26159853) Xu SP … Pang D (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015) 3 60
  5. Large-scale genotyping identifies 41 new loci associated with breast cancer risk. (PMID: 23535729) Michailidou K … Easton DF (Nature genetics 2013) 3 60

Products for EGOT Gene

Sources for EGOT Gene

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