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Aliases for EGID-106632268 Gene

Aliases for EGID-106632268 Gene

  • APOB 3' Scaffold/Matrix Attachment Region (S/MAR) 3
  • APOB 3 Scaffold/Matrix Attachment Region (S/MAR) 3
  • APOB A/T-Rich Hypervariable Region (HVR) 3
  • APOB3MAR 3

External Ids for EGID-106632268 Gene

Summaries for EGID-106632268 Gene

Entrez Gene Summary for EGID-106632268 Gene

  • This region represents a portion of an approximately 50 kb DNase I sensitive domain encompassing the apolipoprotein B (APOB) gene. It includes a matrix attachment region (S/MAR) that coincides with a DNase I hypersensitive site and contains over 30 copies of an approximately 15 nt AT-rich hypervariable repeat. There is also an additional DNase I hypersensitive site further upstream in the 3' UTR of APOB. The S/MAR element can confer position-independent expression to a transgene and functions as an insulator in a Drosophila model system. [provided by RefSeq, Oct 2015]

GeneCards Summary for EGID-106632268 Gene

EGID-106632268 (APOB 3' Scaffold/Matrix Attachment Region (S/MAR)) is an Uncategorized gene.

Additional gene information for EGID-106632268 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for EGID-106632268 Gene

Genomics for EGID-106632268 Gene

Genomic Location for EGID-106632268 Gene

Chromosome:
2
Orientation:
Unknown strand

Genomic View for EGID-106632268 Gene


Cytogenetic band:
GeneLoc Logo Gene Density

No data available for Regulatory Elements and RefSeq DNA sequence for EGID-106632268 Gene

Proteins for EGID-106632268 Gene

Post-translational modifications for EGID-106632268 Gene

No Post-translational modifications

No data available for DME Specific Peptides for EGID-106632268 Gene

Domains & Families for EGID-106632268 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for EGID-106632268 Gene

Function for EGID-106632268 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for EGID-106632268 Gene

Localization for EGID-106632268 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for EGID-106632268 Gene

Pathways & Interactions for EGID-106632268 Gene

SuperPathways for EGID-106632268 Gene

No Data Available

Interacting Proteins for EGID-106632268 Gene

Gene Ontology (GO) - Biological Process for EGID-106632268 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for EGID-106632268 Gene

Drugs & Compounds for EGID-106632268 Gene

No Compound Related Data Available

Transcripts for EGID-106632268 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for EGID-106632268 Gene

No ASD Table

No data available for mRNA/cDNA for EGID-106632268 Gene

Expression for EGID-106632268 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for EGID-106632268 Gene

Orthologs for EGID-106632268 Gene

No data available for Orthologs and Evolution for EGID-106632268 Gene

Paralogs for EGID-106632268 Gene

No data available for Paralogs for EGID-106632268 Gene

Variants for EGID-106632268 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for EGID-106632268 Gene

Disorders for EGID-106632268 Gene

No disorders were found for EGID-106632268 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for EGID-106632268 Gene

Publications for EGID-106632268 Gene

  1. Human matrix attachment regions are necessary for the establishment but not the maintenance of transgene insulation in Drosophila melanogaster. (PMID: 15542833) Namciu SJ … Fournier RE (Molecular and cellular biology 2004) 3 60
  2. Region-specific DNA damage by AT-specific DNA-reactive drugs is predicted by drug binding specificity. (PMID: 10933811) Woynarowski JM … Arnett B (Biochemistry 2000) 3 60
  3. Expression of large genomic clones in transgenic mice: new insights into apolipoprotein B structure, function and regulation. (PMID: 9559266) McCormick SP … Nielsen LB (Current opinion in lipidology 1998) 3 60
  4. Human matrix attachment regions insulate transgene expression from chromosomal position effects in Drosophila melanogaster. (PMID: 9528807) Namciu SJ … Fournier RE (Molecular and cellular biology 1998) 3 60
  5. Evaluation of the function of the human apolipoprotein B gene nuclear matrix association regions in transgenic mice. (PMID: 8906589) Wang DM … Levy-Wilson B (Journal of lipid research 1996) 3 60

Products for EGID-106632268 Gene

Sources for EGID-106632268 Gene

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