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Aliases for EGFR-AS1 Gene

Subcategory (RNA class) for EGFR-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for EGFR-AS1 Gene

  • EGFR Antisense RNA 1 2 3 5

External Ids for EGFR-AS1 Gene

Previous GeneCards Identifiers for EGFR-AS1 Gene

  • GC07M055249

Summaries for EGFR-AS1 Gene

GeneCards Summary for EGFR-AS1 Gene

EGFR-AS1 (EGFR Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for EGFR-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for EGFR-AS1 Gene

Genomics for EGFR-AS1 Gene

Regulatory Elements for EGFR-AS1 Gene

Enhancers for EGFR-AS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07H055124 1.9 FANTOM5 Ensembl ENCODE dbSUPER 11.5 +58.8 58808 11.3 PKNOX1 FOXA2 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ATF7 FOS RUNX3 EGFR EGFR-AS1 SEC61G GC07P055075
GH07H055060 2 FANTOM5 Ensembl ENCODE dbSUPER 10.5 +118.7 118694 19.4 HDGF PKNOX1 FOXA2 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 YBX1 EGFR EGFR-AS1 SEC61G GC07P055075
GH07H055080 1.8 FANTOM5 Ensembl ENCODE dbSUPER 11 +104.1 104082 8 ELF3 FOXA2 TBL1XR1 RB1 MLX BMI1 YBX1 BATF RARA ZSCAN5C EGFR EGFR-AS1 GC07P055075
GH07H054994 1.5 FANTOM5 Ensembl ENCODE 10 +193.1 193068 1.9 HDAC1 ELF3 TBP PKNOX1 FOXA2 TBL1XR1 SIN3A RAD21 BRCA1 RARA EGFR EGFR-AS1 LOC105375284
GH07H055139 1.3 Ensembl ENCODE dbSUPER 11.1 +48.4 48398 2.4 TFAP4 MAX CEBPG EBF1 RAD21 RELA YY1 POLR2A ATF7 RUNX3 EGFR EGFR-AS1 GC07P055075
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around EGFR-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for EGFR-AS1 Gene

Genomic Locations for EGFR-AS1 Gene
chr7:55,179,750-55,188,949
(GRCh38/hg38)
Size:
9,200 bases
Orientation:
Minus strand
chr7:55,247,443-55,256,648
(GRCh37/hg19)

Genomic View for EGFR-AS1 Gene

Genes around EGFR-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
EGFR-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for EGFR-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for EGFR-AS1 Gene

Proteins for EGFR-AS1 Gene

Post-translational modifications for EGFR-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for EGFR-AS1 Gene

Domains & Families for EGFR-AS1 Gene

Gene Families for EGFR-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with EGFR-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for EGFR-AS1 Gene

Function for EGFR-AS1 Gene

Phenotypes From GWAS Catalog for EGFR-AS1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for EGFR-AS1 Gene

Localization for EGFR-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for EGFR-AS1 Gene

Pathways & Interactions for EGFR-AS1 Gene

SuperPathways for EGFR-AS1 Gene

No Data Available

Interacting Proteins for EGFR-AS1 Gene

Gene Ontology (GO) - Biological Process for EGFR-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for EGFR-AS1 Gene

Drugs & Compounds for EGFR-AS1 Gene

No Compound Related Data Available

Transcripts for EGFR-AS1 Gene

mRNA/cDNA for EGFR-AS1 Gene

(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for EGFR-AS1 Gene

EGFR antisense RNA 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for EGFR-AS1 Gene

No ASD Table

Relevant External Links for EGFR-AS1 Gene

GeneLoc Exon Structure for
EGFR-AS1
ECgene alternative splicing isoforms for
EGFR-AS1

Expression for EGFR-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for EGFR-AS1 Gene

SOURCE GeneReport for Unigene cluster for EGFR-AS1 Gene:

Hs.720489
genes like me logo Genes that share expression patterns with EGFR-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for EGFR-AS1 Gene

Orthologs for EGFR-AS1 Gene

Evolution for EGFR-AS1 Gene

ENSEMBL:
Gene Tree for EGFR-AS1 (if available)
TreeFam:
Gene Tree for EGFR-AS1 (if available)

No data available for Orthologs for EGFR-AS1 Gene

Paralogs for EGFR-AS1 Gene

No data available for Paralogs for EGFR-AS1 Gene

Variants for EGFR-AS1 Gene

Sequence variations from dbSNP and Humsavar for EGFR-AS1 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs121913465 Pathogenic 55,181,312(+) GGCCA(G/T)CGTGG nc-transcript-variant, reference, missense
rs397517111 Pathogenic 55,181,319(+) TGGAC(-/GGGTTG)AACCC nc-transcript-variant, cds-indel
rs397517112 Pathogenic 55,181,323(+) CAACC(-/ACC)CCCAC nc-transcript-variant, cds-indel
rs121434569 Likely pathogenic 55,181,378(+) CATCA(C/T)GCAGC nc-transcript-variant, reference, missense
rs397517106 Likely pathogenic 55,181,299(+) AGCCT(-/ACCATC/TCCAGGAAGCCT)ACGTG nc-transcript-variant, cds-indel

Structural Variations from Database of Genomic Variants (DGV) for EGFR-AS1 Gene

Variant ID Type Subtype PubMed ID
esv2734425 CNV deletion 23290073

Relevant External Links for EGFR-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
EGFR-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for EGFR-AS1 Gene

Disorders for EGFR-AS1 Gene

Relevant External Links for EGFR-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
EGFR-AS1

No disorders were found for EGFR-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for EGFR-AS1 Gene

Publications for EGFR-AS1 Gene

  1. The long noncoding RNA, EGFR-AS1, a target of GHR, increases the expression of EGFR in hepatocellular carcinoma. (PMID: 26271667) Qi HL … Liu ZS (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016) 2 3 60
  2. Generation and analysis of 280,000 human expressed sequence tags. (PMID: 8889549) Hillier LD … Marra M (Genome research 1996) 3 60
  3. Long noncoding RNA EGFR-AS1 mediates epidermal growth factor receptor addiction and modulates treatment response in squamous cell carcinoma. (PMID: 28920960) Tan DSW … Iyer NG (Nature medicine 2017) 3

Products for EGFR-AS1 Gene

Sources for EGFR-AS1 Gene

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