Aliases for EGFL7 Gene
External Ids for EGFL7 Gene
Previous GeneCards Identifiers for EGFL7 Gene
This gene encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. The encoded protein may play a role in regulating vasculogenesis. This protein may be involved in the growth and proliferation of tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
GeneCards Summary for EGFL7 Gene
EGFL7 (EGF Like Domain Multiple 7) is a Protein Coding gene. Diseases associated with EGFL7 include Myasthenic Syndrome, Congenital, 17 and Cenani-Lenz Syndactyly Syndrome. GO annotations related to this gene include calcium ion binding and Notch binding. An important paralog of this gene is EGFL8.
UniProtKB/Swiss-Prot for EGFL7 Gene
Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cell adhesion to the extracellular matrix and angiogenesis.